Gene Symbol | BCL11B |
Entrez Gene ID | 64919 |
Full Name | B cell CLL/lymphoma 11B |
Synonyms | ATL1,ATL1-alpha,ATL1-beta,ATL1-delta,ATL1-gamma,CTIP-2,CTIP2,IMD49,RIT1,ZNF856B,hRIT1-alpha |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]. |
Disorder MIM: | |
Disorder Html: | ?Immunodeficiency 49, 617237 (3) |