DCLRE1B cDNA ORF clone, Homo sapiens(human)

The following DCLRE1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DCLRE1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu16705 NM_022836.4
Latest version!
Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$219.50-$307.30
$439.00
OHu33705 NM_001319946.2
Latest version!
Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00
OHu33705 NM_001319947.2
Latest version!
Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00
OHu106776 NM_001363690.2
Latest version!
Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu106779 NM_001363691.2
Latest version!
Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 5, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OHu106776 NM_001363690.1 Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $223.30
$319.00
OHu33705 NM_001319947.1 Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00
OHu106779 NM_001363691.1 Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 5, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
OHu33705 NM_001319946.1 Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $223.30
$319.00
OHu16705 NM_022836.3 Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$219.50-$307.30
$439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu16705
    Clone ID Related Accession (Same CDS sequence) NM_022836.3 , NM_022836.4
    Accession Version NM_022836.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1599bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-10-01
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform a
    Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR005221.1, BC029687.1 and AI669133.1. On May 21, 2010 this sequence version replaced NM_022836.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.162258.1, SRR1803614.276786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGTGA GTCTCAAAAG
    AGGGTGACTA TGTTGACGGC CCCACTGGGA TTTTCAGTGC ACTTAAGGTC TACAGATGAG
    GAGTTTATTT CTCAAAAAAC CAGGGAGGAA ATTGGTTTAG GGTCCCCCTT GGTACCCATG
    GGAGATGATG ATGGAGGTCC AGAAGCCACA GGGAATCAGA GTGCCTGGAT GGGCCATGGT
    TCTCCCCTGT CCCACAGCAG CAAGGGCACC CCTCTTCTAG CTACTGAATT CAGGGGTCTA
    GCACTCAAAT ATCTTCTGAC TCCAGTGAAC TTTTTCCAGG CAGGGTATTC TTCCAGGAGA
    TTTGACCAGC AAGTGGAAAA ATACCATAAA CCCTGCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_073747.1
    CDS295..1893
    Translation

    Target ORF information:

    RefSeq Version NM_022836.3
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_022836.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGTGA GTCTCAAAAG
    AGGGTGACTA TGTTGACGGC CCCACTGGGA TTTTCAGTGC ACTTAAGGTC TACAGATGAG
    GAGTTTATTT CTCAAAAAAC CAGGGAGGAA ATTGGTTTAG GGTCCCCCTT GGTACCCATG
    GGAGATGATG ATGGAGGTCC AGAAGCCACA GGGAATCAGA GTGCCTGGAT GGGCCATGGT
    TCTCCCCTGT CCCACAGCAG CAAGGGCACC CCTCTTCTAG CTACTGAATT CAGGGGTCTA
    GCACTCAAAT ATCTTCTGAC TCCAGTGAAC TTTTTCCAGG CAGGGTATTC TTCCAGGAGA
    TTTGACCAGC AAGTGGAAAA ATACCATAAA CCCTGCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu16705
    Clone ID Related Accession (Same CDS sequence) NM_022836.3 , NM_022836.4
    Accession Version NM_022836.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1599bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-11-16
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform a
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR005221.1, BC029687.1 and AI669133.1. This sequence is a reference standard in the RefSeqGene project. On May 25, 2018 this sequence version replaced NM_022836.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.162258.1, SRR1803614.276786.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000650450.2/ ENSP00000498042.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGTGA GTCTCAAAAG
    AGGGTGACTA TGTTGACGGC CCCACTGGGA TTTTCAGTGC ACTTAAGGTC TACAGATGAG
    GAGTTTATTT CTCAAAAAAC CAGGGAGGAA ATTGGTTTAG GGTCCCCCTT GGTACCCATG
    GGAGATGATG ATGGAGGTCC AGAAGCCACA GGGAATCAGA GTGCCTGGAT GGGCCATGGT
    TCTCCCCTGT CCCACAGCAG CAAGGGCACC CCTCTTCTAG CTACTGAATT CAGGGGTCTA
    GCACTCAAAT ATCTTCTGAC TCCAGTGAAC TTTTTCCAGG CAGGGTATTC TTCCAGGAGA
    TTTGACCAGC AAGTGGAAAA ATACCATAAA CCCTGCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_073747.1
    CDS262..1860
    Translation

    Target ORF information:

    RefSeq Version NM_022836.4
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_022836.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGTGA GTCTCAAAAG
    AGGGTGACTA TGTTGACGGC CCCACTGGGA TTTTCAGTGC ACTTAAGGTC TACAGATGAG
    GAGTTTATTT CTCAAAAAAC CAGGGAGGAA ATTGGTTTAG GGTCCCCCTT GGTACCCATG
    GGAGATGATG ATGGAGGTCC AGAAGCCACA GGGAATCAGA GTGCCTGGAT GGGCCATGGT
    TCTCCCCTGT CCCACAGCAG CAAGGGCACC CCTCTTCTAG CTACTGAATT CAGGGGTCTA
    GCACTCAAAT ATCTTCTGAC TCCAGTGAAC TTTTTCCAGG CAGGGTATTC TTCCAGGAGA
    TTTGACCAGC AAGTGGAAAA ATACCATAAA CCCTGCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu33705
    Clone ID Related Accession (Same CDS sequence) NM_001319947.2 , NM_001319947.1 , NM_001319946.1 , NM_001319946.2
    Accession Version NM_001319947.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1221bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-11-16
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA414122.1, BC029687.1 and AI669133.1. On May 25, 2018 this sequence version replaced NM_001319947.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: CR936679.1, SRR1660803.129023.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2161674, SAMN03267770 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001306876.1
    CDS421..1641
    Translation

    Target ORF information:

    RefSeq Version NM_001319947.2
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001319947.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu33705
    Clone ID Related Accession (Same CDS sequence) NM_001319947.2 , NM_001319947.1 , NM_001319946.1 , NM_001319946.2
    Accession Version NM_001319947.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1221bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-10-02
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform b
    Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA414122.1, BC029687.1 and AI669133.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: CR936679.1, SRR1660803.129023.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2161674, SAMN03267770 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001306876.1
    CDS421..1641
    Translation

    Target ORF information:

    RefSeq Version NM_001319947.1
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001319947.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu33705
    Clone ID Related Accession (Same CDS sequence) NM_001319947.2 , NM_001319947.1 , NM_001319946.1 , NM_001319946.2
    Accession Version NM_001319946.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1221bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-10-02
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform b
    Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR005221.1, CR936679.1 and AI669133.1. On Feb 6, 2016 this sequence version replaced XM_005271130.2. Transcript Variant: This variant (2) lacks an alternate 5' exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.167069.1, CR936679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001306875.1
    CDS507..1727
    Translation

    Target ORF information:

    RefSeq Version NM_001319946.1
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001319946.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu33705
    Clone ID Related Accession (Same CDS sequence) NM_001319947.2 , NM_001319947.1 , NM_001319946.1 , NM_001319946.2
    Accession Version NM_001319946.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1221bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-06-07
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform b
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR005221.1, CR936679.1 and AI669133.1. On May 25, 2018 this sequence version replaced NM_001319946.1. Transcript Variant: This variant (2) lacks an alternate 5' exon compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.167069.1, CR936679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001306875.1
    CDS474..1694
    Translation

    Target ORF information:

    RefSeq Version NM_001319946.2
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001319946.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGT GAGTCTCAAA AGAGGGTGAC TATGTTGACG
    GCCCCACTGG GATTTTCAGT GCACTTAAGG TCTACAGATG AGGAGTTTAT TTCTCAAAAA
    ACCAGGGAGG AAATTGGTTT AGGGTCCCCC TTGGTACCCA TGGGAGATGA TGATGGAGGT
    CCAGAAGCCA CAGGGAATCA GAGTGCCTGG ATGGGCCATG GTTCTCCCCT GTCCCACAGC
    AGCAAGGGCA CCCCTCTTCT AGCTACTGAA TTCAGGGGTC TAGCACTCAA ATATCTTCTG
    ACTCCAGTGA ACTTTTTCCA GGCAGGGTAT TCTTCCAGGA GATTTGACCA GCAAGTGGAA
    AAATACCATA AACCCTGCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106776
    Clone ID Related Accession (Same CDS sequence) NM_001363690.1 , NM_001363690.2
    Accession Version NM_001363690.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1272bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-06-30
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform c
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137856.24. Transcript Variant: This variant (4) includes alternate splicing in the 3' coding region, which results in a frameshift compared to variant 1. The encoded isoform (c) has a shorter and distinct C-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.505321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGCAG GGTATTCTTC
    CAGGAGATTT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001350619.1
    CDS262..1533
    Translation

    Target ORF information:

    RefSeq Version NM_001363690.1
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001363690.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGCAG GGTATTCTTC
    CAGGAGATTT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106776
    Clone ID Related Accession (Same CDS sequence) NM_001363690.1 , NM_001363690.2
    Accession Version NM_001363690.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1272bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-05-30
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform c
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137856.24. On May 31, 2019 this sequence version replaced NM_001363690.1. Transcript Variant: This variant (4) includes alternate splicing in the 3' coding region, which results in a frameshift compared to variant 1. The encoded isoform (c) has a shorter and distinct C-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.505321.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGCAG GGTATTCTTC
    CAGGAGATTT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001350619.1
    CDS262..1533
    Translation

    Target ORF information:

    RefSeq Version NM_001363690.2
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001363690.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAATGGGG TCCTGATCCC CCATACGCCC ATCGCAGTGG ACTTCTGGAG CCTGCGCCGG 
    GCTGGCACCG CACGTCTCTT CTTCTTGTCT CACATGCACT CGGACCACAC CGTGGGCCTG
    TCTAGCACCT GGGCCCGGCC CCTCTACTGC TCCCCAATTA CAGCCCACCT CTTGCATCGT
    CACCTACAGG TATCTAAGCA ATGGATCCAA GCCCTGGAGG TTGGTGAGAG CCATGTATTA
    CCCCTAGATG AAATTGGACA AGAGACCATG ACCGTAACCC TCCTCGATGC CAATCACTGT
    CCTGGTTCTG TCATGTTTCT CTTTGAAGGA TATTTTGGAA CCATCCTCTA CACAGGTGAT
    TTTCGATACA CACCATCCAT GCTAAAGGAG CCAGCCCTGA CACTGGGGAA ACAGATCCAT
    ACTTTATACC TAGACAACAC CAATTGCAAT CCAGCCCTGG TTCTTCCTTC CCGACAAGAA
    GCTGCCCACC AGATTGTCCA GCTCATTCGA AAACACCCAC AACATAACAT AAAGATTGGA
    CTCTACAGCC TGGGAAAGGA ATCACTGCTG GAGCAGCTGG CCCTGGAGTT TCAGACCTGG
    GTGGTATTGA GTCCTCGGCG CCTGGAGTTG GTACAGCTAC TGGGCCTGGC AGATGTGTTC
    ACAGTGGAGG AGAAGGCTGG CCGCATCCAT GCAGTAGACC ATATGGAGAT CTGCCATTCC
    AACATGCTGC GTTGGAACCA GACCCACCCT ACGATTGCTA TCCTTCCCAC AAGCCGAAAA
    ATCCACAGCT CCCACCCTGA TATCCACGTC ATCCCTTACT CTGACCATTC CTCTTACTCC
    GAGCTTCGTG CCTTTGTCGC AGCACTGAAG CCTTGCCAGG TGGTGCCCAT TGTAAGTCGG
    CGGCCCTGTG GAGGCTTTCA GGACAGTCTG AGCCCCAGGA TCTCCGTGCC CCTGATTCCG
    GACTCTGTAC AGCAATACAT GAGTTCTTCC TCTAGAAAAC CAAGCCTTCT CTGGCTGTTA
    GAAAGGAGGC TAAAGAGGCC GAGAACCCAA GGTGTTGTGT TTGAATCCCC TGAGGAAAGT
    GCTGATCAAT CTCAAGCTGA CAGAGACTCA AAGAAGGCCA AGAAAGAGAA ACTTTCTCCC
    TGGCCTGCGG ACCTTGAAAA GCAGCCTTCC CACCATCCTT TGCGGATCAA GAAGCAGTTG
    TTCCCAGATC TCTATAGCAA AGAATGGAAC AAGGCAGTGC CTTTCTGCAG GGTATTCTTC
    CAGGAGATTT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106779
    Clone ID Related Accession (Same CDS sequence) NM_001363691.1 , NM_001363691.2
    Accession Version NM_001363691.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 894bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-06-30
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform d
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137856.24, AF306691.1 and AI669133.1. Transcript Variant: This variant (5) differs in the 5' and 3' coding regions, compared to variant 1. The encoded isoform (d) has a shorter N-terminus and a shorter distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF306691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGC AGGGTATTCT TCCAGGAGAT TTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001350620.1
    CDS474..1367
    Translation

    Target ORF information:

    RefSeq Version NM_001363691.1
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 5, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001363691.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGC AGGGTATTCT TCCAGGAGAT TTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu106779
    Clone ID Related Accession (Same CDS sequence) NM_001363691.1 , NM_001363691.2
    Accession Version NM_001363691.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 894bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-05-30
    Organism Homo sapiens(human)
    Product 5' exonuclease Apollo isoform d
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL137856.24, AF306691.1 and AI669133.1. On May 31, 2019 this sequence version replaced NM_001363691.1. Transcript Variant: This variant (5) differs in the 5' and 3' coding regions, compared to variant 1. The encoded isoform (d) has a shorter N-terminus and a shorter distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF306691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGC AGGGTATTCT TCCAGGAGAT TTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001350620.1
    CDS474..1367
    Translation

    Target ORF information:

    RefSeq Version NM_001363691.2
    Organism Homo sapiens(human)
    Definition Homo sapiens DNA cross-link repair 1B (DCLRE1B), transcript variant 5, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001363691.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCTAAAGG AGCCAGCCCT GACACTGGGG AAACAGATCC ATACTTTATA CCTAGACAAC 
    ACCAATTGCA ATCCAGCCCT GGTTCTTCCT TCCCGACAAG AAGCTGCCCA CCAGATTGTC
    CAGCTCATTC GAAAACACCC ACAACATAAC ATAAAGATTG GACTCTACAG CCTGGGAAAG
    GAATCACTGC TGGAGCAGCT GGCCCTGGAG TTTCAGACCT GGGTGGTATT GAGTCCTCGG
    CGCCTGGAGT TGGTACAGCT ACTGGGCCTG GCAGATGTGT TCACAGTGGA GGAGAAGGCT
    GGCCGCATCC ATGCAGTAGA CCATATGGAG ATCTGCCATT CCAACATGCT GCGTTGGAAC
    CAGACCCACC CTACGATTGC TATCCTTCCC ACAAGCCGAA AAATCCACAG CTCCCACCCT
    GATATCCACG TCATCCCTTA CTCTGACCAT TCCTCTTACT CCGAGCTTCG TGCCTTTGTC
    GCAGCACTGA AGCCTTGCCA GGTGGTGCCC ATTGTAAGTC GGCGGCCCTG TGGAGGCTTT
    CAGGACAGTC TGAGCCCCAG GATCTCCGTG CCCCTGATTC CGGACTCTGT ACAGCAATAC
    ATGAGTTCTT CCTCTAGAAA ACCAAGCCTT CTCTGGCTGT TAGAAAGGAG GCTAAAGAGG
    CCGAGAACCC AAGGTGTTGT GTTTGAATCC CCTGAGGAAA GTGCTGATCA ATCTCAAGCT
    GACAGAGACT CAAAGAAGGC CAAGAAAGAG AAACTTTCTC CCTGGCCTGC GGACCTTGAA
    AAGCAGCCTT CCCACCATCC TTTGCGGATC AAGAAGCAGT TGTTCCCAGA TCTCTATAGC
    AAAGAATGGA ACAAGGCAGT GCCTTTCTGC AGGGTATTCT TCCAGGAGAT TTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities.
    Nucleic acids research43(22)11047-60(2015 Dec)
    Allerston CK,Lee SY,Newman JA,Schofield CJ,McHugh PJ,Gileadi O


    A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
    Cell163(3)712-23(2015 Oct)
    Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M


    The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.
    Human molecular genetics22(24)4901-13(2013 Dec)
    Mason JM,Das I,Arlt M,Patel N,Kraftson S,Glover TW,Sekiguchi JM


    Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
    Nature genetics45(4)353-61, 361e1-2(2013 Apr)
    Michailidou K,Hall P,Gonzalez-Neira A,Ghoussaini M,Dennis J,Milne RL,Schmidt MK,Chang-Claude J,Bojesen SE,Bolla MK,Wang Q,Dicks E,Lee A,Turnbull C,Rahman N,,Fletcher O,Peto J,Gibson L,Dos Santos Silva I,Nevanlinna H,Muranen TA,Aittom?ki K,Blomqvist C,Czene K,Irwanto A,Liu J,Waisfisz Q,Meijers-Heijboer H,Adank M,,van der Luijt RB,Hein R,Dahmen N,Beckman L,Meindl A,Schmutzler RK,M?ller-Myhsok B,Lichtner P,Hopper JL,Southey MC,Makalic E,Schmidt DF,Uitterlinden AG,Hofman A,Hunter DJ,Chanock SJ,Vincent D,Bacot F,Tessier DC,Canisius S,Wessels LF,Haiman CA,Shah M,Luben R,Brown J,Luccarini C,Schoof N,Humphreys K,Li J,Nordestgaard BG,Nielsen SF,Flyger H,Couch FJ,Wang X,Vachon C,Stevens KN,Lambrechts D,Moisse M,Paridaens R,Christiaens MR,Rudolph A,Nickels S,Flesch-Janys D,Johnson N,Aitken Z,Aaltonen K,Heikkinen T,Broeks A,Veer LJ,van der Schoot CE,Gu?nel P,Truong T,Laurent-Puig P,Menegaux F,Marme F,Schneeweiss A,Sohn C,Burwinkel B,Zamora MP,Perez JI,Pita G,Alonso MR,Cox A,Brock IW,Cross SS,Reed MW,Sawyer EJ,Tomlinson I,Kerin MJ,Miller N,Henderson BE,Schumacher F,Le Marchand L,Andrulis IL,Knight JA,Glendon G,Mulligan AM,,,Lindblom A,Margolin S,Hooning MJ,Hollestelle A,van den Ouweland AM,Jager A,Bui QM,Stone J,Dite GS,Apicella C,Tsimiklis H,Giles GG,Severi G,Baglietto L,Fasching PA,Haeberle L,Ekici AB,Beckmann MW,Brenner H,M?ller H,Arndt V,Stegmaier C,Swerdlow A,Ashworth A,Orr N,Jones M,Figueroa J,Lissowska J,Brinton L,Goldberg MS,Labr?che F,Dumont M,Winqvist R,Pylk?s K,Jukkola-Vuorinen A,Grip M,Brauch H,Hamann U,Br?ning T,,Radice P,Peterlongo P,Manoukian S,Bonanni B,Devilee P,Tollenaar RA,Seynaeve C,van Asperen CJ,Jakubowska A,Lubinski J,Jaworska K,Durda K,Mannermaa A,Kataja V,Kosma VM,Hartikainen JM,Bogdanova NV,Antonenkova NN,D?rk T,Kristensen VN,Anton-Culver H,Slager S,Toland AE,Edge S,Fostira F,Kang D,Yoo KY,Noh DY,Matsuo K,Ito H,Iwata H,Sueta A,Wu AH,Tseng CC,Van Den Berg D,Stram DO,Shu XO,Lu W,Gao YT,Cai H,Teo SH,Yip CH,Phuah SY,Cornes BK,Hartman M,Miao H,Lim WY,Sng JH,Muir K,Lophatananon A,Stewart-Brown S,Siriwanarangsan P,Shen CY,Hsiung CN,Wu PE,Ding SL,Sangrajrang S,Gaborieau V,Brennan P,McKay J,Blot WJ,Signorello LB,Cai Q,Zheng W,Deming-Halverson S,Shrubsole M,Long J,Simard J,Garcia-Closas M,Pharoah PD,Chenevix-Trench G,Dunning AM,Benitez J,Easton DF


    A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
    Nature communications42848(2013)
    Grolimund L,Aeby E,Hamelin R,Armand F,Chiappe D,Moniatte M,Lingner J