SHB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SHB
Entrez Gene ID	6461
Full Name	SH2 domain containing adaptor protein B
Synonyms	bA3J10.2
General protein information	Preferred Names SH2 domain containing adaptor protein B Names SH2 domain-containing adapter protein B SHB (Src homology 2 domain containing) adaptor protein B SHB adaptor protein (a Src homology 2 protein) Src homology 2 domain containing adaptor protein B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.1
Disorder MIM:	600314

mRNA and Protein(s)

mRNA	Protein	Name
NM_003028.2	NP_003019.2	SH2 domain-containing adapter protein B
NM_003028.3	NP_003019.2	SH2 domain-containing adapter protein B

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Shb	XP_006238210.1
Pan troglodytes (chimpanzee)	SHB	XP_003312143.2
Canis lupus familiaris (dog)	SHB	XP_538741.4
Xenopus tropicalis (tropical clawed frog)	LOC100489262	XP_002936369.1
Homo sapiens (human)	SHB	NP_003019.2
Mus musculus (house mouse)	Shb	NP_001028478.1
Bos taurus (cattle)	SHB	NP_001179863.1
Gallus gallus (chicken)	SHB	XP_424863.3

Gene Ontology
Bibliography

Related articles in PubMed

Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia.
Jamalpour M, Li X, Cavelier L, Gustafsson K, Mostoslavsky G, H?glund M, Welsh M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(10)1010428317720643(2017 Oct)

Evaluation and validation of commercial antibodies for the detection of Shb.
Vanli G, Cuesta-Marban A, Widmann C
PloS one12(12)e0188311(2017)

The role of the Src Homology-2 domain containing protein B (SHB) in ? cells.
Welsh M, Jamalpour M, Zang G, ?kerblom B
Journal of molecular endocrinology56(1)R21-31(2016 Jan)

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.
Yu B, Zheng Y, Alexander D, Manolio TA, Alonso A, Nettleton JA, Boerwinkle E
Genetic epidemiology37(8)840-5(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

It is concluded that tumor SHB gene expression relates to acute myeloid leukemia survival
Title: Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia.

This article provides a resource for the available molecular tools that can be used in future research on Shb
Title: Evaluation and validation of commercial antibodies for the detection of Shb.

SHB plays a role in integrating adaptive responses to various stimuli by simultaneously modulating cellular responses in different cell-types. [review]
Title: The role of the Src Homology-2 domain containing protein B (SHB) in ? cells.

It is concluded that SHB and angiogenic factors promote the development of cells expressing PDX-1 and insulin in EBs and that such cells can be separated by FACS.
Title: SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.

Taken together, our results suggest that SH2-Bbeta is a new signaling molecule involved in GDNF-induced neurite outgrowth.
Title: Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth.

The following SHB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SHB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25488	NM_003028.3 Latest version!	Homo sapiens SH2 domain containing adaptor protein B (SHB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu25488	NM_003028.2	Homo sapiens SH2 domain containing adaptor protein B (SHB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SHB ( NM_003028.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003019.2 Homo sapiens SH2 domain containing adaptor protein B (SHB), mRNA.

Price & Availability↑

CloneID	OHu25488
Clone ID Related Accession (Same CDS sequence)	NM_003028.2 , NM_003028.3
Accession Version	NM_003028.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	SH2 domain-containing adapter protein B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL161448.16, AL583849.10 and AL138752.5. On Jun 3, 2006 this sequence version replaced NM_003028.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X75342.1, BC136581.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAAGT GGCTAAACAA GTACTTCAGC TTGGGCAACA GCAAGACCAA GAGCCCCCCG 
CAGCCGCCGC GGCCAGACTA CCGCGAGCAG CGGCGCCGAG GCGAGCGGCC TTCGCAGCCC 
CCCCAGGCCG TGCCGCAGGC CTCCTCCGCC GCCTCGGCGT CCTGCGGTCC GGCCACCGCC 
TCCTGCTTCT CAGCCTCTTC GGGCTCGCTG CCCGACGACA GCGGCAGCAC CAGCGACCTC 
ATCCGCGCCT ACCGCGCGCA GAAGGAGCGA GACTTCGAGG ACCCCTACAA CGGGCCTGGC 
TCGTCGCTGC GCAAACTGCG CGCCATGTGC CGCCTGGACT ACTGCGGCGG CAGCGGGGAG 
CCAGGCGGGG TCCAGCGCGC CTTCTCGGCC TCGTCCGCGT CGGGCGCCGC GGGCTGTTGC 
TGCGCCTCCT CGGGCGCGGG GGCCGCCGCG TCCTCGTCCT CGTCCTCCGG CTCTCCGCAT 
CTCTACCGCA GCAGCAGCGA GCGGCGGCCC GCCACGCCGG CCGAGGTGCG CTACATCTCC 
CCCAAGCACC GCCTCATCAA AGTGGAGAGC GCCGCGGGCG GTGGGGCCGG GGACCCCCTG 
GGGGGCGCCT GCGCGGGCGG CCGCACCTGG AGCCCGACGG CCTGCGGAGG CAAGAAACTG 
CTCAACAAGT GCGCCGCCTC AGCCGCGGAG GAGAGCGGGG CCGGCAAGAA GGACAAGGTG 
ACCATAGCCG ATGACTACTC AGATCCCTTT GATGCCAAGA ATGATCTCAA GAGCAAAGCA 
GGAAAGGGGG AGAGTGCTGG CTACATGGAG CCCTATGAGG CACAGAGGAT CATGACAGAA 
TTTCAGAGGC AGGAAAGTGT CCGGTCCCAG CATAAAGGTA TCCAGTTATA TGACACCCCT 
TACGAACCTG AAGGCCAAAG TGTTGACTCA GACTCGGAGA GCACAGTCAG CCCCCGACTG 
CGGGAGAGCA AGCTGCCCCA GGATGACGAC AGGCCCGCCG ATGAGTACGA CCAGCCTTGG 
GAGTGGAACC GGGTCACCAT CCCAGCCCTG GCAGCACAGT TTAATGGCAA CGAGAAGCGG 
CAGTCATCCC CCTCACCTTC GCGGGACCGG CGGCGCCAGC TTCGTGCCCC TGGAGGGGGC 
TTTAAGCCTA TCAAACATGG GAGCCCTGAG TTCTGCGGGA TCCTAGGAGA AAGGGTGGAT 
CCTGCCGTCC CCCTGGAGAA GCAAATATGG TATCACGGAG CCATCAGCAG AGGAGACGCC 
GAGAACCTGC TGCGACTCTG CAAGGAGTGT AGCTACCTTG TCCGGAACAG CCAGACCAGC 
AAGCATGACT ACTCCCTCTC CCTGAGGAGC AACCAGGGTT TTATGCACAT GAAACTGGCC 
AAAACCAAAG AGAAATACGT TCTGGGTCAG AACAGCCCTC CGTTCGACAG TGTCCCGGAA 
GTCATCCACT ACTACACCAC CAGAAAGCTA CCCATCAAAG GGGCTGAGCA CTTGTCCCTC 
CTCTATCCCG TGGCTGTGAG GACCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003019.2
CDS	569..2098
Translation	MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQASSAASASCGPATASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGSGEPGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGGGAGDPLGGACAGGRTWSPTACGGKKLLNKCAASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL

Target ORF information:

RefSeq Version	NM_003028.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing adaptor protein B (SHB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003028.2

ORF Insert Sequence:

ATGGCCAAGT GGCTAAACAA GTACTTCAGC TTGGGCAACA GCAAGACCAA GAGCCCCCCG 
CAGCCGCCGC GGCCAGACTA CCGCGAGCAG CGGCGCCGAG GCGAGCGGCC TTCGCAGCCC 
CCCCAGGCCG TGCCGCAGGC CTCCTCCGCC GCCTCGGCGT CCTGCGGTCC GGCCACCGCC 
TCCTGCTTCT CAGCCTCTTC GGGCTCGCTG CCCGACGACA GCGGCAGCAC CAGCGACCTC 
ATCCGCGCCT ACCGCGCGCA GAAGGAGCGA GACTTCGAGG ACCCCTACAA CGGGCCTGGC 
TCGTCGCTGC GCAAACTGCG CGCCATGTGC CGCCTGGACT ACTGCGGCGG CAGCGGGGAG 
CCAGGCGGGG TCCAGCGCGC CTTCTCGGCC TCGTCCGCGT CGGGCGCCGC GGGCTGTTGC 
TGCGCCTCCT CGGGCGCGGG GGCCGCCGCG TCCTCGTCCT CGTCCTCCGG CTCTCCGCAT 
CTCTACCGCA GCAGCAGCGA GCGGCGGCCC GCCACGCCGG CCGAGGTGCG CTACATCTCC 
CCCAAGCACC GCCTCATCAA AGTGGAGAGC GCCGCGGGCG GTGGGGCCGG GGACCCCCTG 
GGGGGCGCCT GCGCGGGCGG CCGCACCTGG AGCCCGACGG CCTGCGGAGG CAAGAAACTG 
CTCAACAAGT GCGCCGCCTC AGCCGCGGAG GAGAGCGGGG CCGGCAAGAA GGACAAGGTG 
ACCATAGCCG ATGACTACTC AGATCCCTTT GATGCCAAGA ATGATCTCAA GAGCAAAGCA 
GGAAAGGGGG AGAGTGCTGG CTACATGGAG CCCTATGAGG CACAGAGGAT CATGACAGAA 
TTTCAGAGGC AGGAAAGTGT CCGGTCCCAG CATAAAGGTA TCCAGTTATA TGACACCCCT 
TACGAACCTG AAGGCCAAAG TGTTGACTCA GACTCGGAGA GCACAGTCAG CCCCCGACTG 
CGGGAGAGCA AGCTGCCCCA GGATGACGAC AGGCCCGCCG ATGAGTACGA CCAGCCTTGG 
GAGTGGAACC GGGTCACCAT CCCAGCCCTG GCAGCACAGT TTAATGGCAA CGAGAAGCGG 
CAGTCATCCC CCTCACCTTC GCGGGACCGG CGGCGCCAGC TTCGTGCCCC TGGAGGGGGC 
TTTAAGCCTA TCAAACATGG GAGCCCTGAG TTCTGCGGGA TCCTAGGAGA AAGGGTGGAT 
CCTGCCGTCC CCCTGGAGAA GCAAATATGG TATCACGGAG CCATCAGCAG AGGAGACGCC 
GAGAACCTGC TGCGACTCTG CAAGGAGTGT AGCTACCTTG TCCGGAACAG CCAGACCAGC 
AAGCATGACT ACTCCCTCTC CCTGAGGAGC AACCAGGGTT TTATGCACAT GAAACTGGCC 
AAAACCAAAG AGAAATACGT TCTGGGTCAG AACAGCCCTC CGTTCGACAG TGTCCCGGAA 
GTCATCCACT ACTACACCAC CAGAAAGCTA CCCATCAAAG GGGCTGAGCA CTTGTCCCTC 
CTCTATCCCG TGGCTGTGAG GACCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SHB ( NM_003028.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003019.2 Homo sapiens SH2 domain containing adaptor protein B (SHB), mRNA.

Price & Availability↑

CloneID	OHu25488
Clone ID Related Accession (Same CDS sequence)	NM_003028.2 , NM_003028.3
Accession Version	NM_003028.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	SH2 domain-containing adapter protein B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL161448.16, AL583849.10 and AL138752.5. On Nov 23, 2018 this sequence version replaced NM_003028.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X75342.1, BC136581.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377707.4/ ENSP00000366936.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAAGT GGCTAAACAA GTACTTCAGC TTGGGCAACA GCAAGACCAA GAGCCCCCCG 
CAGCCGCCGC GGCCAGACTA CCGCGAGCAG CGGCGCCGAG GCGAGCGGCC TTCGCAGCCC 
CCCCAGGCCG TGCCGCAGGC CTCCTCCGCC GCCTCGGCGT CCTGCGGTCC GGCCACCGCC 
TCCTGCTTCT CAGCCTCTTC GGGCTCGCTG CCCGACGACA GCGGCAGCAC CAGCGACCTC 
ATCCGCGCCT ACCGCGCGCA GAAGGAGCGA GACTTCGAGG ACCCCTACAA CGGGCCTGGC 
TCGTCGCTGC GCAAACTGCG CGCCATGTGC CGCCTGGACT ACTGCGGCGG CAGCGGGGAG 
CCAGGCGGGG TCCAGCGCGC CTTCTCGGCC TCGTCCGCGT CGGGCGCCGC GGGCTGTTGC 
TGCGCCTCCT CGGGCGCGGG GGCCGCCGCG TCCTCGTCCT CGTCCTCCGG CTCTCCGCAT 
CTCTACCGCA GCAGCAGCGA GCGGCGGCCC GCCACGCCGG CCGAGGTGCG CTACATCTCC 
CCCAAGCACC GCCTCATCAA AGTGGAGAGC GCCGCGGGCG GTGGGGCCGG GGACCCCCTG 
GGGGGCGCCT GCGCGGGCGG CCGCACCTGG AGCCCGACGG CCTGCGGAGG CAAGAAACTG 
CTCAACAAGT GCGCCGCCTC AGCCGCGGAG GAGAGCGGGG CCGGCAAGAA GGACAAGGTG 
ACCATAGCCG ATGACTACTC AGATCCCTTT GATGCCAAGA ATGATCTCAA GAGCAAAGCA 
GGAAAGGGGG AGAGTGCTGG CTACATGGAG CCCTATGAGG CACAGAGGAT CATGACAGAA 
TTTCAGAGGC AGGAAAGTGT CCGGTCCCAG CATAAAGGTA TCCAGTTATA TGACACCCCT 
TACGAACCTG AAGGCCAAAG TGTTGACTCA GACTCGGAGA GCACAGTCAG CCCCCGACTG 
CGGGAGAGCA AGCTGCCCCA GGATGACGAC AGGCCCGCCG ATGAGTACGA CCAGCCTTGG 
GAGTGGAACC GGGTCACCAT CCCAGCCCTG GCAGCACAGT TTAATGGCAA CGAGAAGCGG 
CAGTCATCCC CCTCACCTTC GCGGGACCGG CGGCGCCAGC TTCGTGCCCC TGGAGGGGGC 
TTTAAGCCTA TCAAACATGG GAGCCCTGAG TTCTGCGGGA TCCTAGGAGA AAGGGTGGAT 
CCTGCCGTCC CCCTGGAGAA GCAAATATGG TATCACGGAG CCATCAGCAG AGGAGACGCC 
GAGAACCTGC TGCGACTCTG CAAGGAGTGT AGCTACCTTG TCCGGAACAG CCAGACCAGC 
AAGCATGACT ACTCCCTCTC CCTGAGGAGC AACCAGGGTT TTATGCACAT GAAACTGGCC 
AAAACCAAAG AGAAATACGT TCTGGGTCAG AACAGCCCTC CGTTCGACAG TGTCCCGGAA 
GTCATCCACT ACTACACCAC CAGAAAGCTA CCCATCAAAG GGGCTGAGCA CTTGTCCCTC 
CTCTATCCCG TGGCTGTGAG GACCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003019.2
CDS	583..2112
Translation	MAKWLNKYFSLGNSKTKSPPQPPRPDYREQRRRGERPSQPPQAVPQASSAASASCGPATASCFSASSGSLPDDSGSTSDLIRAYRAQKERDFEDPYNGPGSSLRKLRAMCRLDYCGGSGEPGGVQRAFSASSASGAAGCCCASSGAGAAASSSSSSGSPHLYRSSSERRPATPAEVRYISPKHRLIKVESAAGGGAGDPLGGACAGGRTWSPTACGGKKLLNKCAASAAEESGAGKKDKVTIADDYSDPFDAKNDLKSKAGKGESAGYMEPYEAQRIMTEFQRQESVRSQHKGIQLYDTPYEPEGQSVDSDSESTVSPRLRESKLPQDDDRPADEYDQPWEWNRVTIPALAAQFNGNEKRQSSPSPSRDRRRQLRAPGGGFKPIKHGSPEFCGILGERVDPAVPLEKQIWYHGAISRGDAENLLRLCKECSYLVRNSQTSKHDYSLSLRSNQGFMHMKLAKTKEKYVLGQNSPPFDSVPEVIHYYTTRKLPIKGAEHLSLLYPVAVRTL

Target ORF information:

RefSeq Version	NM_003028.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing adaptor protein B (SHB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003028.3

ORF Insert Sequence:

ATGGCCAAGT GGCTAAACAA GTACTTCAGC TTGGGCAACA GCAAGACCAA GAGCCCCCCG 
CAGCCGCCGC GGCCAGACTA CCGCGAGCAG CGGCGCCGAG GCGAGCGGCC TTCGCAGCCC 
CCCCAGGCCG TGCCGCAGGC CTCCTCCGCC GCCTCGGCGT CCTGCGGTCC GGCCACCGCC 
TCCTGCTTCT CAGCCTCTTC GGGCTCGCTG CCCGACGACA GCGGCAGCAC CAGCGACCTC 
ATCCGCGCCT ACCGCGCGCA GAAGGAGCGA GACTTCGAGG ACCCCTACAA CGGGCCTGGC 
TCGTCGCTGC GCAAACTGCG CGCCATGTGC CGCCTGGACT ACTGCGGCGG CAGCGGGGAG 
CCAGGCGGGG TCCAGCGCGC CTTCTCGGCC TCGTCCGCGT CGGGCGCCGC GGGCTGTTGC 
TGCGCCTCCT CGGGCGCGGG GGCCGCCGCG TCCTCGTCCT CGTCCTCCGG CTCTCCGCAT 
CTCTACCGCA GCAGCAGCGA GCGGCGGCCC GCCACGCCGG CCGAGGTGCG CTACATCTCC 
CCCAAGCACC GCCTCATCAA AGTGGAGAGC GCCGCGGGCG GTGGGGCCGG GGACCCCCTG 
GGGGGCGCCT GCGCGGGCGG CCGCACCTGG AGCCCGACGG CCTGCGGAGG CAAGAAACTG 
CTCAACAAGT GCGCCGCCTC AGCCGCGGAG GAGAGCGGGG CCGGCAAGAA GGACAAGGTG 
ACCATAGCCG ATGACTACTC AGATCCCTTT GATGCCAAGA ATGATCTCAA GAGCAAAGCA 
GGAAAGGGGG AGAGTGCTGG CTACATGGAG CCCTATGAGG CACAGAGGAT CATGACAGAA 
TTTCAGAGGC AGGAAAGTGT CCGGTCCCAG CATAAAGGTA TCCAGTTATA TGACACCCCT 
TACGAACCTG AAGGCCAAAG TGTTGACTCA GACTCGGAGA GCACAGTCAG CCCCCGACTG 
CGGGAGAGCA AGCTGCCCCA GGATGACGAC AGGCCCGCCG ATGAGTACGA CCAGCCTTGG 
GAGTGGAACC GGGTCACCAT CCCAGCCCTG GCAGCACAGT TTAATGGCAA CGAGAAGCGG 
CAGTCATCCC CCTCACCTTC GCGGGACCGG CGGCGCCAGC TTCGTGCCCC TGGAGGGGGC 
TTTAAGCCTA TCAAACATGG GAGCCCTGAG TTCTGCGGGA TCCTAGGAGA AAGGGTGGAT 
CCTGCCGTCC CCCTGGAGAA GCAAATATGG TATCACGGAG CCATCAGCAG AGGAGACGCC 
GAGAACCTGC TGCGACTCTG CAAGGAGTGT AGCTACCTTG TCCGGAACAG CCAGACCAGC 
AAGCATGACT ACTCCCTCTC CCTGAGGAGC AACCAGGGTT TTATGCACAT GAAACTGGCC 
AAAACCAAAG AGAAATACGT TCTGGGTCAG AACAGCCCTC CGTTCGACAG TGTCCCGGAA 
GTCATCCACT ACTACACCAC CAGAAAGCTA CCCATCAAAG GGGCTGAGCA CTTGTCCCTC 
CTCTATCCCG TGGCTGTGAG GACCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tumor SHB gene expression affects disease characteristics in human acute myeloid leukemia.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(10)1010428317720643(2017 Oct)
Jamalpour M,Li X,Cavelier L,Gustafsson K,Mostoslavsky G,H?glund M,Welsh M

Evaluation and validation of commercial antibodies for the detection of Shb.
PloS one12(12)e0188311(2017)
Vanli G,Cuesta-Marban A,Widmann C

The role of the Src Homology-2 domain containing protein B (SHB) in ? cells.
Journal of molecular endocrinology56(1)R21-31(2016 Jan)
Welsh M,Jamalpour M,Zang G,?kerblom B

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.
Molecular & cellular proteomics : MCP13(7)1705-23(2014 Jul)
Leung KK,Hause RJ Jr,Barkinge JL,Ciaccio MF,Chuu CP,Jones RB

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.
Genetic epidemiology37(8)840-5(2013 Dec)
Yu B,Zheng Y,Alexander D,Manolio TA,Alonso A,Nettleton JA,Boerwinkle E

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SHB cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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