The following POLR1E gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POLR1E cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu11924 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_022490.3 , NM_022490.2 | |
| Accession Version | NM_022490.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-05-01 | |
| Organism | Homo sapiens(human) | |
| Product | DNA-directed RNA polymerase I subunit RPA49 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7, AK024032.1 and BC001337.1. On Nov 22, 2018 this sequence version replaced NM_022490.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1142558.1, SRR1803612.273198.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_071935.1 |
| CDS | 101..1360 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_022490.3 |
1 | ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu11924 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_022490.3 , NM_022490.2 | |
| Accession Version | NM_022490.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Homo sapiens(human) | |
| Product | DNA-directed RNA polymerase I subunit RPA49 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7, AK024032.1 and BC001337.1. On Sep 19, 2013 this sequence version replaced NM_022490.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC001337.1, BC014331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_071935.1 |
| CDS | 114..1373 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_022490.2 |
1 | ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu14186 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001282766.1 | |
| Accession Version | NM_001282766.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1050bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-24 | |
| Organism | Homo sapiens(human) | |
| Product | DNA-directed RNA polymerase I subunit RPA49 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7, AK303167.1 and BC001337.1. On Sep 19, 2013 this sequence version replaced XM_005251548.1. Transcript Variant: This variant (2) uses an alternate exon the coding region which results in the use of downstream start codon compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK303167.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGATGCTGA ATTGTTCAAC ATGCAGCCAC TATTTTCAGG TCTTTCACCA AGAAAGCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001269695.1 |
| CDS | 418..1467 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001282766.1 |
1 | ATGATGCTGA ATTGTTCAAC ATGCAGCCAC TATTTTCAGG TCTTTCACCA AGAAAGCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu42823 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005251547.2 | |
| Accession Version | XM_005251547.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-05 | |
| Organism | Homo sapiens(human) | |
| Product | DNA-directed RNA polymerase I subunit RPA49 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005251547.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTACCAGG CCTCTGCTGT CAGCCTCCTT CCGCGAGACA TTCCCTCCTG TCACAGCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005251604.1 |
| CDS | 173..1618 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005251547.2 |
1 | ATGTACCAGG CCTCTGCTGT CAGCCTCCTT CCGCGAGACA TTCCCTCCTG TCACAGCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu108813 | |
| Clone ID Related Accession (Same CDS sequence) | NM_022490.4 | |
| Accession Version | NM_022490.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-14 | |
| Organism | Homo sapiens(human) | |
| Product | DNA-directed RNA polymerase I subunit RPA49 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158156.7. On Aug 31, 2019 this sequence version replaced NM_022490.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK023452.1, BC001337.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377798.9/ ENSP00000367029.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_071935.1 |
| CDS | 101..1360 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_022490.4 |
1 | ATGGCGGCGG AGGTGTTGCC GAGTGCGAGG TGGCAGTATT GTGGGGCGCC CGACGGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7. |
The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription. |
Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription. |
Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth. |
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |
