KLHL25 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KLHL25
Entrez Gene ID	64410
Full Name	kelch like family member 25
Synonyms	ENC-2,ENC2
General protein information	Preferred Names kelch like family member 25 Names kelch-like protein 25 BTB/POZ KELCH domain protein ectoderm-neural cortex protein 2 ectodermal-neural cortex 2 kelch-like 25
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q25.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_022480.4	NP_071925.2	kelch-like protein 25
NM_022480.3	NP_071925.2	kelch-like protein 25

Pathways from BioSystems

Homologies

Bos taurus (cattle)	KLHL25	NP_001179615.1
	KLHL25	XP_001086777.1
Homo sapiens (human)	KLHL25	NP_071925.2
Canis lupus familiaris (dog)	KLHL25	XP_005618396.1
Pan troglodytes (chimpanzee)	KLHL25	XP_510571.2
Rattus norvegicus (Norway rat)	Klhl25	NP_001034095.1
Gallus gallus (chicken)	KLHL25	XP_004943913.1
Mus musculus (house mouse)	Klhl25	NP_001116252.1
Xenopus tropicalis (tropical clawed frog)	klhl25	NP_001072541.1

Gene Ontology
Bibliography

Related articles in PubMed

Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.
Zhang C, Liu J, Huang G, Zhao Y, Yue X, Wu H, Li J, Zhu J, Shen Z, Haffty BG, Hu W, Feng Z
Genes & development30(17)1956-70(2016 Sep)

Evidence for shared genetic risk between methamphetamine-induced psychosis and schizophrenia.
Ikeda M, Okahisa Y, Aleksic B, Won M, Kondo N, Naruse N, Aoyama-Uehara K, Sora I, Iyo M, Hashimoto R, Kawamura Y, Nishida N, Miyagawa T, Takeda M, Sasaki T, Tokunaga K, Ozaki N, Ujike H, Iwata N
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology38(10)1864-70(2013 Sep)

Update on the Kelch-like (KLHL) gene family.
Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS
Human genomics713(2013 May)

A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
Chung S, Low SK, Zembutsu H, Takahashi A, Kubo M, Sasa M, Nakamura Y
Breast cancer research : BCR15(5)R81(2013)

Translational homeostasis via the mRNA cap-binding protein, eIF4E.
Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N
Molecular cell46(6)847-58(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CUL3 interacts with ACLY through its adaptor protein, KLHL25 (Kelch-like family member 25), to ubiquitinate and degrade ACLY in cells
Title: Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.

The following KLHL25 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLHL25 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15634	NM_022480.4 Latest version!	Homo sapiens kelch like family member 25 (KLHL25), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu15634	NM_022480.3	Homo sapiens kelch like family member 25 (KLHL25), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KLHL25 ( NM_022480.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071925.2 Homo sapiens kelch like family member 25 (KLHL25), mRNA.

Price & Availability↑

CloneID	OHu15634
Clone ID Related Accession (Same CDS sequence)	NM_022480.4 , NM_022480.3
Accession Version	NM_022480.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	kelch-like protein 25
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA337553.1, DB063745.1 and AY764034.1. On Nov 23, 2018 this sequence version replaced NM_022480.3. ##Evidence-Data-START## Transcript exon combination :: AY764034.1, AK092231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000337975.6/ ENSP00000336800.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGTCA GTGTCCATGA GACCCGCAAG TCGCGGAGCA GCACGGGGTC CATGAACGTC 
ACCCTCTTCC ACAAGGCCTC CCACCCGGAC TGTGTGCTGG CCCACCTCAA CACGCTTCGC 
AAGCACTGCA TGTTCACCGA CGTCACACTC TGGGCGGGCG ACCGTGCCTT CCCCTGTCAC 
CGTGCCGTGC TGGCCGCCTC TAGCCGCTAT TTTGAGGCCA TGTTCAGCCA TGGCCTTCGG 
GAGAGCCGGG ATGACACTGT CAACTTCCAG GACAACCTGC ACCCGGAGGT GCTGGAGCTG 
CTGCTGGACT TTGCCTACTC CTCACGCATC GCCATCAACG AGGAGAACGC TGAGTCACTG 
CTGGAGGCAG GCGACATGCT GCAGTTCCAC GATGTGCGGG ATGCTGCCGC CGAGTTCCTG 
GAGAAGAACC TTTTCCCCTC CAACTGCCTG GGCATGATGC TGCTCTCGGA CGCCCACCAG 
TGCCGCCGGC TGTATGAGTT CTCCTGGCGC ATGTGCCTGG TGCACTTTGA GACGGTGAGG 
CAGAGCGAGG ACTTCAACAG CCTGTCCAAG GACACACTGC TGGACCTCAT CTCGAGTGAT 
GAGCTGGAGA CCGAGGACGA GCGGGTGGTC TTCGAGGCCA TCCTCCAGTG GGTGAAGCAC 
GACCTGGAGC CACGGAAGGT CCACTTGCCC GAGCTCCTCC GCAGCGTGCG TCTGGCCTTG 
CTGCCGTCCG ACTGCCTGCA GGAGGCCGTC TCCAGCGAGG CCCTCCTCAT GGCAGACGAG 
CGCACCAAGC TTATCATGGA TGAGGCCCTG CGCTGCAAGA CCAGGATCCT GCAGAATGAT 
GGCGTGGTCA CCAGCCCCTG TGCCCGGCCA CGCAAGGCGG GCCACACGCT ACTCATCCTG 
GGGGGCCAGA CCTTCATGTG TGACAAGATC TACCAGGTGG ACCACAAGGC CAAGGAGATC 
ATCCCCAAGG CCGACCTGCC CAGCCCCCGG AAGGAGTTCA GCGCCTCAGC GATCGGCTGC 
AAGGTCTATG TGACGGGGGG CAGGGGCTCC GAGAACGGGG TCTCCAAGGA TGTCTGGGTG 
TACGACACCG TACATGAGGA ATGGTCCAAG GCGGCGCCCA TGCTGATTGC CCGCTTTGGC 
CATGGCTCAG CTGAGCTGGA GAACTGCCTC TATGTGGTGG GGGGACACAC ATCCCTGGCA 
GGGGTCTTCC CGGCCTCGCC TTCTGTCTCC CTGAAACAAG TGGAGAAATA CGACCCTGGG 
GCCAACAAGT GGATGATGGT GGCCCCCTTG CGGGATGGCG TCAGCAATGC CGCAGTGGTG 
AGTGCCAAGC TGAAGCTCTT TGTTTTCGGA GGAACCAGCA TCCACCGGGA CATGGTGTCC 
AAGGTCCAGT GCTATGACCC CTCGGAGAAC AGGTGGACGA TCAAGGCCGA GTGCCCCCAG 
CCTTGGCGGT ACACAGCCGC TGCCGTCCTG GGCAGCCAGA TCTTCATCAT GGGAGGTGAC 
ACGGAATTCA CAGCCGCCTC GGCCTACCGC TTTGACTGTG AGACCAACCA GTGGACGCGG 
ATTGGGGACA TGACTGCCAA GCGCATGTCC TGCCATGCCC TGGCTTCCGG CAACAAGCTC 
TATGTGGTCG GGGGCTACTT TGGGACCCAG AGGTGTAAGA CTCTGGACTG CTATGACCCC 
ACTTCAGATA CATGGAACTG CATCACCACA GTGCCCTACT CACTTATCCC CACGGCCTTT 
GTCAGCACCT GGAAGCACCT GCCCGCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071925.2
CDS	171..1940
Translation	MSVSVHETRKSRSSTGSMNVTLFHKASHPDCVLAHLNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIAINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLFPSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFETVRQSEDFNSLSKDTLLDLISSDELETEDERVVFEAILQWVKHDLEPRKVHLPELLRSVRLALLPSDCLQEAVSSEALLMADERTKLIMDEALRCKTRILQNDGVVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSASAIGCKVYVTGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTSLAGVFPASPSVSLKQVEKYDPGANKWMMVAPLRDGVSNAAVVSAKLKLFVFGGTSIHRDMVSKVQCYDPSENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETNQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPA

Target ORF information:

RefSeq Version	NM_022480.4
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 25 (KLHL25), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022480.4

ORF Insert Sequence:

ATGTCGGTCA GTGTCCATGA GACCCGCAAG TCGCGGAGCA GCACGGGGTC CATGAACGTC 
ACCCTCTTCC ACAAGGCCTC CCACCCGGAC TGTGTGCTGG CCCACCTCAA CACGCTTCGC 
AAGCACTGCA TGTTCACCGA CGTCACACTC TGGGCGGGCG ACCGTGCCTT CCCCTGTCAC 
CGTGCCGTGC TGGCCGCCTC TAGCCGCTAT TTTGAGGCCA TGTTCAGCCA TGGCCTTCGG 
GAGAGCCGGG ATGACACTGT CAACTTCCAG GACAACCTGC ACCCGGAGGT GCTGGAGCTG 
CTGCTGGACT TTGCCTACTC CTCACGCATC GCCATCAACG AGGAGAACGC TGAGTCACTG 
CTGGAGGCAG GCGACATGCT GCAGTTCCAC GATGTGCGGG ATGCTGCCGC CGAGTTCCTG 
GAGAAGAACC TTTTCCCCTC CAACTGCCTG GGCATGATGC TGCTCTCGGA CGCCCACCAG 
TGCCGCCGGC TGTATGAGTT CTCCTGGCGC ATGTGCCTGG TGCACTTTGA GACGGTGAGG 
CAGAGCGAGG ACTTCAACAG CCTGTCCAAG GACACACTGC TGGACCTCAT CTCGAGTGAT 
GAGCTGGAGA CCGAGGACGA GCGGGTGGTC TTCGAGGCCA TCCTCCAGTG GGTGAAGCAC 
GACCTGGAGC CACGGAAGGT CCACTTGCCC GAGCTCCTCC GCAGCGTGCG TCTGGCCTTG 
CTGCCGTCCG ACTGCCTGCA GGAGGCCGTC TCCAGCGAGG CCCTCCTCAT GGCAGACGAG 
CGCACCAAGC TTATCATGGA TGAGGCCCTG CGCTGCAAGA CCAGGATCCT GCAGAATGAT 
GGCGTGGTCA CCAGCCCCTG TGCCCGGCCA CGCAAGGCGG GCCACACGCT ACTCATCCTG 
GGGGGCCAGA CCTTCATGTG TGACAAGATC TACCAGGTGG ACCACAAGGC CAAGGAGATC 
ATCCCCAAGG CCGACCTGCC CAGCCCCCGG AAGGAGTTCA GCGCCTCAGC GATCGGCTGC 
AAGGTCTATG TGACGGGGGG CAGGGGCTCC GAGAACGGGG TCTCCAAGGA TGTCTGGGTG 
TACGACACCG TACATGAGGA ATGGTCCAAG GCGGCGCCCA TGCTGATTGC CCGCTTTGGC 
CATGGCTCAG CTGAGCTGGA GAACTGCCTC TATGTGGTGG GGGGACACAC ATCCCTGGCA 
GGGGTCTTCC CGGCCTCGCC TTCTGTCTCC CTGAAACAAG TGGAGAAATA CGACCCTGGG 
GCCAACAAGT GGATGATGGT GGCCCCCTTG CGGGATGGCG TCAGCAATGC CGCAGTGGTG 
AGTGCCAAGC TGAAGCTCTT TGTTTTCGGA GGAACCAGCA TCCACCGGGA CATGGTGTCC 
AAGGTCCAGT GCTATGACCC CTCGGAGAAC AGGTGGACGA TCAAGGCCGA GTGCCCCCAG 
CCTTGGCGGT ACACAGCCGC TGCCGTCCTG GGCAGCCAGA TCTTCATCAT GGGAGGTGAC 
ACGGAATTCA CAGCCGCCTC GGCCTACCGC TTTGACTGTG AGACCAACCA GTGGACGCGG 
ATTGGGGACA TGACTGCCAA GCGCATGTCC TGCCATGCCC TGGCTTCCGG CAACAAGCTC 
TATGTGGTCG GGGGCTACTT TGGGACCCAG AGGTGTAAGA CTCTGGACTG CTATGACCCC 
ACTTCAGATA CATGGAACTG CATCACCACA GTGCCCTACT CACTTATCCC CACGGCCTTT 
GTCAGCACCT GGAAGCACCT GCCCGCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KLHL25 ( NM_022480.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071925.2 Homo sapiens kelch like family member 25 (KLHL25), mRNA.

Price & Availability↑

CloneID	OHu15634
Clone ID Related Accession (Same CDS sequence)	NM_022480.4 , NM_022480.3
Accession Version	NM_022480.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1770bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	kelch-like protein 25
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA337553.1, DB063745.1 and AY764034.1. On or before Jun 11, 2008 this sequence version replaced XM_001721166.1, XM_001719329.1, XM_001721147.1, NM_022480.2. ##Evidence-Data-START## Transcript exon combination :: AY764034.1, AK092231.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGTCA GTGTCCATGA GACCCGCAAG TCGCGGAGCA GCACGGGGTC CATGAACGTC 
ACCCTCTTCC ACAAGGCCTC CCACCCGGAC TGTGTGCTGG CCCACCTCAA CACGCTTCGC 
AAGCACTGCA TGTTCACCGA CGTCACACTC TGGGCGGGCG ACCGTGCCTT CCCCTGTCAC 
CGTGCCGTGC TGGCCGCCTC TAGCCGCTAT TTTGAGGCCA TGTTCAGCCA TGGCCTTCGG 
GAGAGCCGGG ATGACACTGT CAACTTCCAG GACAACCTGC ACCCGGAGGT GCTGGAGCTG 
CTGCTGGACT TTGCCTACTC CTCACGCATC GCCATCAACG AGGAGAACGC TGAGTCACTG 
CTGGAGGCAG GCGACATGCT GCAGTTCCAC GATGTGCGGG ATGCTGCCGC CGAGTTCCTG 
GAGAAGAACC TTTTCCCCTC CAACTGCCTG GGCATGATGC TGCTCTCGGA CGCCCACCAG 
TGCCGCCGGC TGTATGAGTT CTCCTGGCGC ATGTGCCTGG TGCACTTTGA GACGGTGAGG 
CAGAGCGAGG ACTTCAACAG CCTGTCCAAG GACACACTGC TGGACCTCAT CTCGAGTGAT 
GAGCTGGAGA CCGAGGACGA GCGGGTGGTC TTCGAGGCCA TCCTCCAGTG GGTGAAGCAC 
GACCTGGAGC CACGGAAGGT CCACTTGCCC GAGCTCCTCC GCAGCGTGCG TCTGGCCTTG 
CTGCCGTCCG ACTGCCTGCA GGAGGCCGTC TCCAGCGAGG CCCTCCTCAT GGCAGACGAG 
CGCACCAAGC TTATCATGGA TGAGGCCCTG CGCTGCAAGA CCAGGATCCT GCAGAATGAT 
GGCGTGGTCA CCAGCCCCTG TGCCCGGCCA CGCAAGGCGG GCCACACGCT ACTCATCCTG 
GGGGGCCAGA CCTTCATGTG TGACAAGATC TACCAGGTGG ACCACAAGGC CAAGGAGATC 
ATCCCCAAGG CCGACCTGCC CAGCCCCCGG AAGGAGTTCA GCGCCTCAGC GATCGGCTGC 
AAGGTCTATG TGACGGGGGG CAGGGGCTCC GAGAACGGGG TCTCCAAGGA TGTCTGGGTG 
TACGACACCG TACATGAGGA ATGGTCCAAG GCGGCGCCCA TGCTGATTGC CCGCTTTGGC 
CATGGCTCAG CTGAGCTGGA GAACTGCCTC TATGTGGTGG GGGGACACAC ATCCCTGGCA 
GGGGTCTTCC CGGCCTCGCC TTCTGTCTCC CTGAAACAAG TGGAGAAATA CGACCCTGGG 
GCCAACAAGT GGATGATGGT GGCCCCCTTG CGGGATGGCG TCAGCAATGC CGCAGTGGTG 
AGTGCCAAGC TGAAGCTCTT TGTTTTCGGA GGAACCAGCA TCCACCGGGA CATGGTGTCC 
AAGGTCCAGT GCTATGACCC CTCGGAGAAC AGGTGGACGA TCAAGGCCGA GTGCCCCCAG 
CCTTGGCGGT ACACAGCCGC TGCCGTCCTG GGCAGCCAGA TCTTCATCAT GGGAGGTGAC 
ACGGAATTCA CAGCCGCCTC GGCCTACCGC TTTGACTGTG AGACCAACCA GTGGACGCGG 
ATTGGGGACA TGACTGCCAA GCGCATGTCC TGCCATGCCC TGGCTTCCGG CAACAAGCTC 
TATGTGGTCG GGGGCTACTT TGGGACCCAG AGGTGTAAGA CTCTGGACTG CTATGACCCC 
ACTTCAGATA CATGGAACTG CATCACCACA GTGCCCTACT CACTTATCCC CACGGCCTTT 
GTCAGCACCT GGAAGCACCT GCCCGCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071925.2
CDS	204..1973
Translation	MSVSVHETRKSRSSTGSMNVTLFHKASHPDCVLAHLNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTVNFQDNLHPEVLELLLDFAYSSRIAINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLFPSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFETVRQSEDFNSLSKDTLLDLISSDELETEDERVVFEAILQWVKHDLEPRKVHLPELLRSVRLALLPSDCLQEAVSSEALLMADERTKLIMDEALRCKTRILQNDGVVTSPCARPRKAGHTLLILGGQTFMCDKIYQVDHKAKEIIPKADLPSPRKEFSASAIGCKVYVTGGRGSENGVSKDVWVYDTVHEEWSKAAPMLIARFGHGSAELENCLYVVGGHTSLAGVFPASPSVSLKQVEKYDPGANKWMMVAPLRDGVSNAAVVSAKLKLFVFGGTSIHRDMVSKVQCYDPSENRWTIKAECPQPWRYTAAAVLGSQIFIMGGDTEFTAASAYRFDCETNQWTRIGDMTAKRMSCHALASGNKLYVVGGYFGTQRCKTLDCYDPTSDTWNCITTVPYSLIPTAFVSTWKHLPA

Target ORF information:

RefSeq Version	NM_022480.3
Organism	Homo sapiens(human)
Definition	Homo sapiens kelch like family member 25 (KLHL25), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022480.3

ORF Insert Sequence:

ATGTCGGTCA GTGTCCATGA GACCCGCAAG TCGCGGAGCA GCACGGGGTC CATGAACGTC 
ACCCTCTTCC ACAAGGCCTC CCACCCGGAC TGTGTGCTGG CCCACCTCAA CACGCTTCGC 
AAGCACTGCA TGTTCACCGA CGTCACACTC TGGGCGGGCG ACCGTGCCTT CCCCTGTCAC 
CGTGCCGTGC TGGCCGCCTC TAGCCGCTAT TTTGAGGCCA TGTTCAGCCA TGGCCTTCGG 
GAGAGCCGGG ATGACACTGT CAACTTCCAG GACAACCTGC ACCCGGAGGT GCTGGAGCTG 
CTGCTGGACT TTGCCTACTC CTCACGCATC GCCATCAACG AGGAGAACGC TGAGTCACTG 
CTGGAGGCAG GCGACATGCT GCAGTTCCAC GATGTGCGGG ATGCTGCCGC CGAGTTCCTG 
GAGAAGAACC TTTTCCCCTC CAACTGCCTG GGCATGATGC TGCTCTCGGA CGCCCACCAG 
TGCCGCCGGC TGTATGAGTT CTCCTGGCGC ATGTGCCTGG TGCACTTTGA GACGGTGAGG 
CAGAGCGAGG ACTTCAACAG CCTGTCCAAG GACACACTGC TGGACCTCAT CTCGAGTGAT 
GAGCTGGAGA CCGAGGACGA GCGGGTGGTC TTCGAGGCCA TCCTCCAGTG GGTGAAGCAC 
GACCTGGAGC CACGGAAGGT CCACTTGCCC GAGCTCCTCC GCAGCGTGCG TCTGGCCTTG 
CTGCCGTCCG ACTGCCTGCA GGAGGCCGTC TCCAGCGAGG CCCTCCTCAT GGCAGACGAG 
CGCACCAAGC TTATCATGGA TGAGGCCCTG CGCTGCAAGA CCAGGATCCT GCAGAATGAT 
GGCGTGGTCA CCAGCCCCTG TGCCCGGCCA CGCAAGGCGG GCCACACGCT ACTCATCCTG 
GGGGGCCAGA CCTTCATGTG TGACAAGATC TACCAGGTGG ACCACAAGGC CAAGGAGATC 
ATCCCCAAGG CCGACCTGCC CAGCCCCCGG AAGGAGTTCA GCGCCTCAGC GATCGGCTGC 
AAGGTCTATG TGACGGGGGG CAGGGGCTCC GAGAACGGGG TCTCCAAGGA TGTCTGGGTG 
TACGACACCG TACATGAGGA ATGGTCCAAG GCGGCGCCCA TGCTGATTGC CCGCTTTGGC 
CATGGCTCAG CTGAGCTGGA GAACTGCCTC TATGTGGTGG GGGGACACAC ATCCCTGGCA 
GGGGTCTTCC CGGCCTCGCC TTCTGTCTCC CTGAAACAAG TGGAGAAATA CGACCCTGGG 
GCCAACAAGT GGATGATGGT GGCCCCCTTG CGGGATGGCG TCAGCAATGC CGCAGTGGTG 
AGTGCCAAGC TGAAGCTCTT TGTTTTCGGA GGAACCAGCA TCCACCGGGA CATGGTGTCC 
AAGGTCCAGT GCTATGACCC CTCGGAGAAC AGGTGGACGA TCAAGGCCGA GTGCCCCCAG 
CCTTGGCGGT ACACAGCCGC TGCCGTCCTG GGCAGCCAGA TCTTCATCAT GGGAGGTGAC 
ACGGAATTCA CAGCCGCCTC GGCCTACCGC TTTGACTGTG AGACCAACCA GTGGACGCGG 
ATTGGGGACA TGACTGCCAA GCGCATGTCC TGCCATGCCC TGGCTTCCGG CAACAAGCTC 
TATGTGGTCG GGGGCTACTT TGGGACCCAG AGGTGTAAGA CTCTGGACTG CTATGACCCC 
ACTTCAGATA CATGGAACTG CATCACCACA GTGCCCTACT CACTTATCCC CACGGCCTTT 
GTCAGCACCT GGAAGCACCT GCCCGCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.
Genes & development30(17)1956-70(2016 Sep)
Zhang C,Liu J,Huang G,Zhao Y,Yue X,Wu H,Li J,Zhu J,Shen Z,Haffty BG,Hu W,Feng Z

Evidence for shared genetic risk between methamphetamine-induced psychosis and schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology38(10)1864-70(2013 Sep)
Ikeda M,Okahisa Y,Aleksic B,Won M,Kondo N,Naruse N,Aoyama-Uehara K,Sora I,Iyo M,Hashimoto R,Kawamura Y,Nishida N,Miyagawa T,Takeda M,Sasaki T,Tokunaga K,Ozaki N,Ujike H,Iwata N

Update on the Kelch-like (KLHL) gene family.
Human genomics713(2013 May)
Dhanoa BS,Cogliati T,Satish AG,Bruford EA,Friedman JS

A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
Breast cancer research : BCR15(5)R81(2013)
Chung S,Low SK,Zembutsu H,Takahashi A,Kubo M,Sasa M,Nakamura Y

Translational homeostasis via the mRNA cap-binding protein, eIF4E.
Molecular cell46(6)847-58(2012 Jun)
Yanagiya A,Suyama E,Adachi H,Svitkin YV,Aza-Blanc P,Imataka H,Mikami S,Martineau Y,Ronai ZA,Sonenberg N

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KLHL25 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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