PGA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PGA3
Entrez Gene ID	643834
Full Name	pepsinogen 3, group I (pepsinogen A)
General protein information	Preferred Names pepsinogen 3, group I (pepsinogen A) Names pepsin A-3 pepsinogen A3 pepsinogen-3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q12.2
Summary	This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015].
Disorder MIM:	169710

mRNA and Protein(s)

mRNA	Protein	Name
NM_001079807.3	NP_001073275.1	pepsin A-3 preproprotein
NM_001079807.4	NP_001073275.1	pepsin A-3 preproprotein

Pathways from BioSystems

Homologies

Homo sapiens (human)	PGA5	NP_055039.1
Pan troglodytes (chimpanzee)	PGA4	XP_001145457.1
	PGA4	NP_001098064.1
Homo sapiens (human)	PGA3	NP_001073275.1
Homo sapiens (human)	PGA4	NP_001073276.1
Gallus gallus (chicken)	LOC395926	NP_990385.1
Bos taurus (cattle)	PGA5	NP_001001600.2
Canis lupus familiaris (dog)	PGA	NP_001003117.1
Xenopus tropicalis (tropical clawed frog)	pga4	XP_002942158.1

Gene Ontology
Bibliography

Related articles in PubMed

Temporal changes in serum biomarkers and risk for progression of gastric precancerous lesions: a longitudinal study.
Tu H, Sun L, Dong X, Gong Y, Xu Q, Jing J, Long Q, Flanders WD, Bostick RM, Yuan Y
International journal of cancer136(2)425-34(2015 Jan)

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.
Zhang XM, Li JX, Zhang GY, Li XH, Gu H
BMC gastroenterology143(2014 Jan)

Screening of precancerous gastric lesions by serum pepsinogen, gastrin-17, anti-helicobacter pylori and anti- CagA antibodies in dyspeptic patients over 50 years old in Guilan Province, north of .
Mansour-Ghanaei F, Joukar F, Rajpout Y, Hasandokht T
Asian Pacific journal of cancer prevention : APJCP15(18)7635-8(2014)

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.
Terasawa T, Nishida H, Kato K, Miyashiro I, Yoshikawa T, Takaku R, Hamashima C
PloS one9(10)e109783(2014)

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.
Kageyama T
Cellular and molecular life sciences : CMLS59(2)288-306(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High serum Pepsinogen I level is associ9ated with the progression of gastric precancerous lesions.
Title: Temporal changes in serum biomarkers and risk for progression of gastric precancerous lesions: a longitudinal study.

Low Pepsinogen I is associated with precancerous gastric lesions.
Title: Screening of precancerous gastric lesions by serum pepsinogen, gastrin-17, anti-helicobacter pylori and anti- CagA antibodies in dyspeptic patients over 50 years old in Guilan Province, north of .

Significantly higher AUC was observed for the PGI/PGII ratio and is associated with atrophy and intestinal metaplasia.
Title: Serum gastrin and the pepsinogen I/II ratio as markers for diagnosis of premalignant gastric lesions.

A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I in atrophic gastritis patients with gastroesophageal reflux.
Title: Correlation of serum pepsinogens and gastrin-17 with atrophic gastritis in gastroesophageal reflux patients: a matched-pairs study.

Barrett's esophagus is characterized by the absence of Helicobacter pylori infection and high levels of serum pepsinogen I concentration in Japan.
Title: Barrett's esophagus is characterized by the absence of Helicobacter pylori infection and high levels of serum pepsinogen I concentration in Japan.

The following PGA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PGA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10185	NM_001079807.4 Latest version!	Homo sapiens pepsinogen A3 (PGA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu10185	NM_001079807.3	Homo sapiens pepsinogen 3, group I (pepsinogen A) (PGA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PGA3 ( NM_001079807.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073275.1 Homo sapiens pepsinogen 3, group I (pepsinogen A) (PGA3), mRNA.

Price & Availability↑

CloneID	OHu10185
Clone ID Related Accession (Same CDS sequence)	NM_001079807.3 , NM_001079807.4
Accession Version	NM_001079807.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	pepsin A-3 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312941.1, AP000437.5 and AK225679.1. On Jul 30, 2015 this sequence version replaced NM_001079807.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225679.1, AK225669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTGGC TGCTGCTGCT GGGTCTGGTG GCACTCTCTG AGTGCATCAT GTACAAGGTC 
CCCCTCATCA GAAAGAAGTC CTTGAGGCGC ACCCTGTCCG AGCGTGGCCT GCTGAAGGAC 
TTCCTGAAGA AGCACAACCT CAACCCAGCC AGAAAGTACT TCCCCCAGTG GAAGGCTCCC 
ACCCTGGTAG ATGAACAGCC CCTGGAGAAC TACCTGGATA TGGAGTACTT CGGCACTATC 
GGCATCGGAA CTCCTGCCCA GGATTTCACC GTCGTCTTTG ACACCGGCTC CTCCAACCTG 
TGGGTGCCCT CAGTCTACTG CTCCAGTCTT GCCTGCACCA ACCACAACCG CTTCAACCCT 
GAGGATTCTT CCACCTACCA GTCCACCAGC GAGACAGTCT CCATCACCTA CGGCACCGGC 
AGCATGACAG GCATCCTCGG ATACGACACT GTCCAGGTTG GAGGCATCTC TGACACCAAT 
CAGATCTTCG GCCTGAGCGA GACGGAACCT GGCTCCTTCC TGTATTATGC TCCCTTCGAT 
GGCATCCTGG GGCTGGCCTA CCCCAGCATT TCCTCCTCCG GGGCCACACC CGTCTTTGAC 
AACATCTGGA ACCAGGGCCT GGTTTCTCAG GACCTCTTCT CTGTCTACCT CAGCGCCGAT 
GACCAGAGTG GCAGCGTGGT GATCTTTGGT GGCATTGACT CTTCTTACTA CACTGGAAGT 
CTGAACTGGG TGCCTGTTAC CGTCGAGGGT TACTGGCAGA TCACCGTGGA CAGCATCACC 
ATGAACGGAG AGGCCATCGC CTGCGCTGAG GGCTGCCAGG CCATTGTTGA CACCGGCACC 
TCTCTGCTGA CCGGCCCAAC CAGCCCCATT GCCAACATCC AGAGCGACAT CGGAGCCAGC 
GAGAACTCAG ATGGCGACAT GGTGGTCAGC TGCTCAGCCA TCAGCAGCCT GCCCGACATC 
GTCTTCACCA TCAATGGAGT CCAGTACCCC GTGCCACCCA GTGCCTACAT CCTGCAGAGC 
GAGGGGAGCT GCATCAGTGG CTTCCAGGGC ATGAACCTCC CCACCGAATC TGGAGAGCTT 
TGGATCCTGG GTGATGTCTT CATCCGCCAG TACTTTACCG TCTTCGACAG GGCAAACAAC 
CAGGTCGGCC TGGCCCCCGT GGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073275.1
CDS	53..1219
Translation	MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA

Target ORF information:

RefSeq Version	NM_001079807.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pepsinogen 3, group I (pepsinogen A) (PGA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079807.3

ORF Insert Sequence:

ATGAAGTGGC TGCTGCTGCT GGGTCTGGTG GCACTCTCTG AGTGCATCAT GTACAAGGTC 
CCCCTCATCA GAAAGAAGTC CTTGAGGCGC ACCCTGTCCG AGCGTGGCCT GCTGAAGGAC 
TTCCTGAAGA AGCACAACCT CAACCCAGCC AGAAAGTACT TCCCCCAGTG GAAGGCTCCC 
ACCCTGGTAG ATGAACAGCC CCTGGAGAAC TACCTGGATA TGGAGTACTT CGGCACTATC 
GGCATCGGAA CTCCTGCCCA GGATTTCACC GTCGTCTTTG ACACCGGCTC CTCCAACCTG 
TGGGTGCCCT CAGTCTACTG CTCCAGTCTT GCCTGCACCA ACCACAACCG CTTCAACCCT 
GAGGATTCTT CCACCTACCA GTCCACCAGC GAGACAGTCT CCATCACCTA CGGCACCGGC 
AGCATGACAG GCATCCTCGG ATACGACACT GTCCAGGTTG GAGGCATCTC TGACACCAAT 
CAGATCTTCG GCCTGAGCGA GACGGAACCT GGCTCCTTCC TGTATTATGC TCCCTTCGAT 
GGCATCCTGG GGCTGGCCTA CCCCAGCATT TCCTCCTCCG GGGCCACACC CGTCTTTGAC 
AACATCTGGA ACCAGGGCCT GGTTTCTCAG GACCTCTTCT CTGTCTACCT CAGCGCCGAT 
GACCAGAGTG GCAGCGTGGT GATCTTTGGT GGCATTGACT CTTCTTACTA CACTGGAAGT 
CTGAACTGGG TGCCTGTTAC CGTCGAGGGT TACTGGCAGA TCACCGTGGA CAGCATCACC 
ATGAACGGAG AGGCCATCGC CTGCGCTGAG GGCTGCCAGG CCATTGTTGA CACCGGCACC 
TCTCTGCTGA CCGGCCCAAC CAGCCCCATT GCCAACATCC AGAGCGACAT CGGAGCCAGC 
GAGAACTCAG ATGGCGACAT GGTGGTCAGC TGCTCAGCCA TCAGCAGCCT GCCCGACATC 
GTCTTCACCA TCAATGGAGT CCAGTACCCC GTGCCACCCA GTGCCTACAT CCTGCAGAGC 
GAGGGGAGCT GCATCAGTGG CTTCCAGGGC ATGAACCTCC CCACCGAATC TGGAGAGCTT 
TGGATCCTGG GTGATGTCTT CATCCGCCAG TACTTTACCG TCTTCGACAG GGCAAACAAC 
CAGGTCGGCC TGGCCCCCGT GGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PGA3 ( NM_001079807.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073275.1 Homo sapiens pepsinogen A3 (PGA3), mRNA.

Price & Availability↑

CloneID	OHu10185
Clone ID Related Accession (Same CDS sequence)	NM_001079807.3 , NM_001079807.4
Accession Version	NM_001079807.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	pepsin A-3 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312941.1, AP000437.5 and AK225679.1. On May 17, 2019 this sequence version replaced NM_001079807.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225679.1, AK225669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000325558.11/ ENSP00000322192.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGTGGC TGCTGCTGCT GGGTCTGGTG GCACTCTCTG AGTGCATCAT GTACAAGGTC 
CCCCTCATCA GAAAGAAGTC CTTGAGGCGC ACCCTGTCCG AGCGTGGCCT GCTGAAGGAC 
TTCCTGAAGA AGCACAACCT CAACCCAGCC AGAAAGTACT TCCCCCAGTG GAAGGCTCCC 
ACCCTGGTAG ATGAACAGCC CCTGGAGAAC TACCTGGATA TGGAGTACTT CGGCACTATC 
GGCATCGGAA CTCCTGCCCA GGATTTCACC GTCGTCTTTG ACACCGGCTC CTCCAACCTG 
TGGGTGCCCT CAGTCTACTG CTCCAGTCTT GCCTGCACCA ACCACAACCG CTTCAACCCT 
GAGGATTCTT CCACCTACCA GTCCACCAGC GAGACAGTCT CCATCACCTA CGGCACCGGC 
AGCATGACAG GCATCCTCGG ATACGACACT GTCCAGGTTG GAGGCATCTC TGACACCAAT 
CAGATCTTCG GCCTGAGCGA GACGGAACCT GGCTCCTTCC TGTATTATGC TCCCTTCGAT 
GGCATCCTGG GGCTGGCCTA CCCCAGCATT TCCTCCTCCG GGGCCACACC CGTCTTTGAC 
AACATCTGGA ACCAGGGCCT GGTTTCTCAG GACCTCTTCT CTGTCTACCT CAGCGCCGAT 
GACCAGAGTG GCAGCGTGGT GATCTTTGGT GGCATTGACT CTTCTTACTA CACTGGAAGT 
CTGAACTGGG TGCCTGTTAC CGTCGAGGGT TACTGGCAGA TCACCGTGGA CAGCATCACC 
ATGAACGGAG AGGCCATCGC CTGCGCTGAG GGCTGCCAGG CCATTGTTGA CACCGGCACC 
TCTCTGCTGA CCGGCCCAAC CAGCCCCATT GCCAACATCC AGAGCGACAT CGGAGCCAGC 
GAGAACTCAG ATGGCGACAT GGTGGTCAGC TGCTCAGCCA TCAGCAGCCT GCCCGACATC 
GTCTTCACCA TCAATGGAGT CCAGTACCCC GTGCCACCCA GTGCCTACAT CCTGCAGAGC 
GAGGGGAGCT GCATCAGTGG CTTCCAGGGC ATGAACCTCC CCACCGAATC TGGAGAGCTT 
TGGATCCTGG GTGATGTCTT CATCCGCCAG TACTTTACCG TCTTCGACAG GGCAAACAAC 
CAGGTCGGCC TGGCCCCCGT GGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073275.1
CDS	51..1217
Translation	MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA

Target ORF information:

RefSeq Version	NM_001079807.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pepsinogen A3 (PGA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001079807.4

ORF Insert Sequence:

ATGAAGTGGC TGCTGCTGCT GGGTCTGGTG GCACTCTCTG AGTGCATCAT GTACAAGGTC 
CCCCTCATCA GAAAGAAGTC CTTGAGGCGC ACCCTGTCCG AGCGTGGCCT GCTGAAGGAC 
TTCCTGAAGA AGCACAACCT CAACCCAGCC AGAAAGTACT TCCCCCAGTG GAAGGCTCCC 
ACCCTGGTAG ATGAACAGCC CCTGGAGAAC TACCTGGATA TGGAGTACTT CGGCACTATC 
GGCATCGGAA CTCCTGCCCA GGATTTCACC GTCGTCTTTG ACACCGGCTC CTCCAACCTG 
TGGGTGCCCT CAGTCTACTG CTCCAGTCTT GCCTGCACCA ACCACAACCG CTTCAACCCT 
GAGGATTCTT CCACCTACCA GTCCACCAGC GAGACAGTCT CCATCACCTA CGGCACCGGC 
AGCATGACAG GCATCCTCGG ATACGACACT GTCCAGGTTG GAGGCATCTC TGACACCAAT 
CAGATCTTCG GCCTGAGCGA GACGGAACCT GGCTCCTTCC TGTATTATGC TCCCTTCGAT 
GGCATCCTGG GGCTGGCCTA CCCCAGCATT TCCTCCTCCG GGGCCACACC CGTCTTTGAC 
AACATCTGGA ACCAGGGCCT GGTTTCTCAG GACCTCTTCT CTGTCTACCT CAGCGCCGAT 
GACCAGAGTG GCAGCGTGGT GATCTTTGGT GGCATTGACT CTTCTTACTA CACTGGAAGT 
CTGAACTGGG TGCCTGTTAC CGTCGAGGGT TACTGGCAGA TCACCGTGGA CAGCATCACC 
ATGAACGGAG AGGCCATCGC CTGCGCTGAG GGCTGCCAGG CCATTGTTGA CACCGGCACC 
TCTCTGCTGA CCGGCCCAAC CAGCCCCATT GCCAACATCC AGAGCGACAT CGGAGCCAGC 
GAGAACTCAG ATGGCGACAT GGTGGTCAGC TGCTCAGCCA TCAGCAGCCT GCCCGACATC 
GTCTTCACCA TCAATGGAGT CCAGTACCCC GTGCCACCCA GTGCCTACAT CCTGCAGAGC 
GAGGGGAGCT GCATCAGTGG CTTCCAGGGC ATGAACCTCC CCACCGAATC TGGAGAGCTT 
TGGATCCTGG GTGATGTCTT CATCCGCCAG TACTTTACCG TCTTCGACAG GGCAAACAAC 
CAGGTCGGCC TGGCCCCCGT GGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Temporal changes in serum biomarkers and risk for progression of gastric precancerous lesions: a longitudinal study.
International journal of cancer136(2)425-34(2015 Jan)
Tu H,Sun L,Dong X,Gong Y,Xu Q,Jing J,Long Q,Flanders WD,Bostick RM,Yuan Y

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.
BMC gastroenterology143(2014 Jan)
Zhang XM,Li JX,Zhang GY,Li XH,Gu H

Screening of precancerous gastric lesions by serum pepsinogen, gastrin-17, anti-helicobacter pylori and anti- CagA antibodies in dyspeptic patients over 50 years old in Guilan Province, north of Iran.
Asian Pacific journal of cancer prevention : APJCP15(18)7635-8(2014)
Mansour-Ghanaei F,Joukar F,Rajpout Y,Hasandokht T

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.
PloS one9(10)e109783(2014)
Terasawa T,Nishida H,Kato K,Miyashiro I,Yoshikawa T,Takaku R,Hamashima C

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.
Cellular and molecular life sciences : CMLS59(2)288-306(2002 Feb)
Kageyama T

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PGA3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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