SRSF4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SRSF4
Entrez Gene ID	6429
Full Name	serine and arginine rich splicing factor 4
Synonyms	SFRS4,SRP75
General protein information	Preferred Names serine and arginine rich splicing factor 4 Names serine/arginine-rich splicing factor 4 SR splicing factor 4 SRP001LB pre-mRNA-splicing factor SRP75 splicing factor, arginine/serine-rich 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p35.3
Summary	This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009].
Disorder MIM:	601940

mRNA and Protein(s)

mRNA	Protein	Name
NM_005626.5	NP_005617.2	serine/arginine-rich splicing factor 4
XM_011541951.2	XP_011540253.1	serine/arginine-rich splicing factor 4 isoform X1
NM_005626.4	NP_005617.2	serine/arginine-rich splicing factor 4
XM_011541951.3	XP_011540253.1	serine/arginine-rich splicing factor 4 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Srsf4	NP_065612.2
Rattus norvegicus (Norway rat)	Srsf4	NP_001102155.1
Homo sapiens (human)	SRSF4	NP_005617.2
	SRSF4	XP_001113540.1
Bos taurus (cattle)	SRSF4	NP_001094701.1
Gallus gallus (chicken)	SRSF4	XP_004947787.1
Canis lupus familiaris (dog)	SRSF4	XP_005617748.1
Pan troglodytes (chimpanzee)	SRSF4	XP_001155042.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis.
Gabriel M, Delforge Y, Deward A, Habraken Y, Hennuy B, Piette J, Klinck R, Chabot B, Colige A, Lambert C
BMC cancer15227(2015 Apr)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Many of the splicing alterations induced by cisplatin are caused by SRSF4 and they contribute to apoptosis in a process requires class I PI3K.
Title: Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis.

SRp75 inhibits splicing of tau exon 10 by binding to the CA repeat in the intronic splicing silencer downstream of the exon, and requires hnRNPG to exert its full regulatory effect on tau exon 10.
Title: An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia.

Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3.
Title: Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3.

the c.1002-1110_1113delTAAG mutation creates a new intronic splicing regulatory element in intron 6b of the CFTR gene exclusively recognized by SRp75
Title: Characterization of a disease-associated mutation affecting a putative splicing regulatory element in intron 6b of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

The following SRSF4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SRSF4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12604	NM_005626.5 Latest version!	Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu60447	XM_011541951.3 Latest version!	Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu12604	NM_005626.4	Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu60447	XM_011541951.2	Homo sapiens serine/arginine-rich splicing factor 4 (SRSF4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SRSF4 ( NM_005626.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005617.2 Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), mRNA.

Price & Availability↑

CloneID	OHu12604
Clone ID Related Accession (Same CDS sequence)	NM_005626.5 , NM_005626.4
Accession Version	NM_005626.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	serine/arginine-rich splicing factor 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590729.14, BC002781.2 and CV814357.1. On Nov 22, 2018 this sequence version replaced NM_005626.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.805643.1, SRR1660803.180030.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373795.7/ ENSP00000362900.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CTCGCTCTCG AAGCAGACAT 
TCCCGTAAGA GCAGAAGCCG AAGTGGCAGC AGCAAAAGCA GTCATTCTAA GAGTAGATCT 
CGGTCCAGGT CGGGCTCCCG CTCCCGGAGC AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC 
CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT 
AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA GACCAAGCTG AAGAGAAGAT CCAAAACAAT 
GACAATGTCG GGAAACCCAA GAGCCGGAGT CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT 
CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC 
AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC 
AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC AAGGACAAGA GGAAGGGCAG GAAGAGAAGC 
AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA 
GGCAGCAAGC GAGACAGCAA GGCGGGCAGC AGCAAGAAGA AGAAGAAGGA AGACACTGAC 
CGCTCCCAGT CCAGATCTCC ATCCCGCTCC GTGTCAAAGG AGCGGGAACA TGCCAAGTCT 
GAATCCAGCC AGAGGGAAGG TCGAGGAGAG AGTGAGAATG CTGGCACCAA TCAGGAGACC 
CGGTCCAGGT CGAGATCCAA TTCCAAATCG AAACCAAACC TTCCATCAGA ATCACGCTCC 
AGATCAAAGT CAGCTTCAAA AACCCGATCT CGGTCCAAGT CTAGATCCAG GTCTGCTTCC 
AGATCGCCCT CCCGATCTAG ATCTAGGTCC CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005617.2
CDS	149..1633
Translation	MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS

Target ORF information:

RefSeq Version	NM_005626.5
Organism	Homo sapiens(human)
Definition	Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005626.5

ORF Insert Sequence:

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CTCGCTCTCG AAGCAGACAT 
TCCCGTAAGA GCAGAAGCCG AAGTGGCAGC AGCAAAAGCA GTCATTCTAA GAGTAGATCT 
CGGTCCAGGT CGGGCTCCCG CTCCCGGAGC AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC 
CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT 
AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA GACCAAGCTG AAGAGAAGAT CCAAAACAAT 
GACAATGTCG GGAAACCCAA GAGCCGGAGT CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT 
CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC 
AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC 
AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC AAGGACAAGA GGAAGGGCAG GAAGAGAAGC 
AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA 
GGCAGCAAGC GAGACAGCAA GGCGGGCAGC AGCAAGAAGA AGAAGAAGGA AGACACTGAC 
CGCTCCCAGT CCAGATCTCC ATCCCGCTCC GTGTCAAAGG AGCGGGAACA TGCCAAGTCT 
GAATCCAGCC AGAGGGAAGG TCGAGGAGAG AGTGAGAATG CTGGCACCAA TCAGGAGACC 
CGGTCCAGGT CGAGATCCAA TTCCAAATCG AAACCAAACC TTCCATCAGA ATCACGCTCC 
AGATCAAAGT CAGCTTCAAA AACCCGATCT CGGTCCAAGT CTAGATCCAG GTCTGCTTCC 
AGATCGCCCT CCCGATCTAG ATCTAGGTCC CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRSF4 ( NM_005626.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005617.2 Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), mRNA.

Price & Availability↑

CloneID	OHu12604
Clone ID Related Accession (Same CDS sequence)	NM_005626.5 , NM_005626.4
Accession Version	NM_005626.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	serine/arginine-rich splicing factor 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC391985.1, AL590729.14, BC002781.2 and CV814357.1. On Feb 27, 2009 this sequence version replaced NM_005626.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.180030.1, SRR1660803.148181.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CTCGCTCTCG AAGCAGACAT 
TCCCGTAAGA GCAGAAGCCG AAGTGGCAGC AGCAAAAGCA GTCATTCTAA GAGTAGATCT 
CGGTCCAGGT CGGGCTCCCG CTCCCGGAGC AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC 
CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT 
AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA GACCAAGCTG AAGAGAAGAT CCAAAACAAT 
GACAATGTCG GGAAACCCAA GAGCCGGAGT CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT 
CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC 
AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC 
AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC AAGGACAAGA GGAAGGGCAG GAAGAGAAGC 
AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA 
GGCAGCAAGC GAGACAGCAA GGCGGGCAGC AGCAAGAAGA AGAAGAAGGA AGACACTGAC 
CGCTCCCAGT CCAGATCTCC ATCCCGCTCC GTGTCAAAGG AGCGGGAACA TGCCAAGTCT 
GAATCCAGCC AGAGGGAAGG TCGAGGAGAG AGTGAGAATG CTGGCACCAA TCAGGAGACC 
CGGTCCAGGT CGAGATCCAA TTCCAAATCG AAACCAAACC TTCCATCAGA ATCACGCTCC 
AGATCAAAGT CAGCTTCAAA AACCCGATCT CGGTCCAAGT CTAGATCCAG GTCTGCTTCC 
AGATCGCCCT CCCGATCTAG ATCTAGGTCC CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005617.2
CDS	374..1858
Translation	MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS

Target ORF information:

RefSeq Version	NM_005626.4
Organism	Homo sapiens(human)
Definition	Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005626.4

ORF Insert Sequence:

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CTCGCTCTCG AAGCAGACAT 
TCCCGTAAGA GCAGAAGCCG AAGTGGCAGC AGCAAAAGCA GTCATTCTAA GAGTAGATCT 
CGGTCCAGGT CGGGCTCCCG CTCCCGGAGC AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC 
CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT 
AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA GACCAAGCTG AAGAGAAGAT CCAAAACAAT 
GACAATGTCG GGAAACCCAA GAGCCGGAGT CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT 
CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC 
AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC 
AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC AAGGACAAGA GGAAGGGCAG GAAGAGAAGC 
AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA 
GGCAGCAAGC GAGACAGCAA GGCGGGCAGC AGCAAGAAGA AGAAGAAGGA AGACACTGAC 
CGCTCCCAGT CCAGATCTCC ATCCCGCTCC GTGTCAAAGG AGCGGGAACA TGCCAAGTCT 
GAATCCAGCC AGAGGGAAGG TCGAGGAGAG AGTGAGAATG CTGGCACCAA TCAGGAGACC 
CGGTCCAGGT CGAGATCCAA TTCCAAATCG AAACCAAACC TTCCATCAGA ATCACGCTCC 
AGATCAAAGT CAGCTTCAAA AACCCGATCT CGGTCCAAGT CTAGATCCAG GTCTGCTTCC 
AGATCGCCCT CCCGATCTAG ATCTAGGTCC CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRSF4 ( XM_011541951.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540253.1 Homo sapiens serine/arginine-rich splicing factor 4 (SRSF4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu60447
Clone ID Related Accession (Same CDS sequence)	XM_011541951.2 , XM_011541951.3
Accession Version	XM_011541951.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	serine/arginine-rich splicing factor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541951.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CGGGCTCCCG CTCCCGGAGC 
AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC 
AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA 
GACCAAGCTG AAGAGAAGAT CCAAAACAAT GACAATGTCG GGAAACCCAA GAGCCGGAGT 
CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG 
GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT 
CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC 
AAGGACAAGA GGAAGGGCAG GAAGAGAAGC AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC 
CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA GGCAGCAAGC GAGACAGCAA GGCGGGCAGC 
AGCAAGAAGA AGAAGAAGGA AGACACTGAC CGCTCCCAGT CCAGATCTCC ATCCCGCTCC 
GTGTCAAAGG AGCGGGAACA TGCCAAGTCT GAATCCAGCC AGAGGGAAGG TCGAGGAGAG 
AGTGAGAATG CTGGCACCAA TCAGGAGACC CGGTCCAGGT CGAGATCCAA TTCCAAATCG 
AAACCAAACC TTCCATCAGA ATCACGCTCC AGATCAAAGT CAGCTTCAAA AACCCGATCT 
CGGTCCAAGT CTAGATCCAG GTCTGCTTCC AGATCGCCCT CCCGATCTAG ATCTAGGTCC 
CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540253.1
CDS	174..1568
Translation	MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS

Target ORF information:

RefSeq Version	XM_011541951.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/arginine-rich splicing factor 4 (SRSF4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541951.2

ORF Insert Sequence:

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CGGGCTCCCG CTCCCGGAGC 
AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC 
AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA 
GACCAAGCTG AAGAGAAGAT CCAAAACAAT GACAATGTCG GGAAACCCAA GAGCCGGAGT 
CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG 
GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT 
CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC 
AAGGACAAGA GGAAGGGCAG GAAGAGAAGC AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC 
CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA GGCAGCAAGC GAGACAGCAA GGCGGGCAGC 
AGCAAGAAGA AGAAGAAGGA AGACACTGAC CGCTCCCAGT CCAGATCTCC ATCCCGCTCC 
GTGTCAAAGG AGCGGGAACA TGCCAAGTCT GAATCCAGCC AGAGGGAAGG TCGAGGAGAG 
AGTGAGAATG CTGGCACCAA TCAGGAGACC CGGTCCAGGT CGAGATCCAA TTCCAAATCG 
AAACCAAACC TTCCATCAGA ATCACGCTCC AGATCAAAGT CAGCTTCAAA AACCCGATCT 
CGGTCCAAGT CTAGATCCAG GTCTGCTTCC AGATCGCCCT CCCGATCTAG ATCTAGGTCC 
CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRSF4 ( XM_011541951.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540253.1 Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), transcript variant X1, mRNA.

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CloneID	OHu60447
Clone ID Related Accession (Same CDS sequence)	XM_011541951.2 , XM_011541951.3
Accession Version	XM_011541951.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine/arginine-rich splicing factor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011541951.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CGGGCTCCCG CTCCCGGAGC 
AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC 
AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA 
GACCAAGCTG AAGAGAAGAT CCAAAACAAT GACAATGTCG GGAAACCCAA GAGCCGGAGT 
CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG 
GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT 
CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC 
AAGGACAAGA GGAAGGGCAG GAAGAGAAGC AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC 
CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA GGCAGCAAGC GAGACAGCAA GGCGGGCAGC 
AGCAAGAAGA AGAAGAAGGA AGACACTGAC CGCTCCCAGT CCAGATCTCC ATCCCGCTCC 
GTGTCAAAGG AGCGGGAACA TGCCAAGTCT GAATCCAGCC AGAGGGAAGG TCGAGGAGAG 
AGTGAGAATG CTGGCACCAA TCAGGAGACC CGGTCCAGGT CGAGATCCAA TTCCAAATCG 
AAACCAAACC TTCCATCAGA ATCACGCTCC AGATCAAAGT CAGCTTCAAA AACCCGATCT 
CGGTCCAAGT CTAGATCCAG GTCTGCTTCC AGATCGCCCT CCCGATCTAG ATCTAGGTCC 
CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540253.1
CDS	147..1541
Translation	MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS

Target ORF information:

RefSeq Version	XM_011541951.3
Organism	Homo sapiens(human)
Definition	Homo sapiens serine and arginine rich splicing factor 4 (SRSF4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011541951.3

ORF Insert Sequence:

ATGCCGCGGG TGTACATCGG CCGCCTGAGC TACCAGGCCC GGGAGCGCGA TGTGGAGCGC 
TTCTTTAAGG GCTACGGGAA GATCCTGGAG GTGGATCTGA AGAACGGATA TGGTTTTGTG 
GAGTTTGATG ATCTGCGTGA TGCAGATGAT GCTGTTTATG AACTGAATGG CAAAGACCTT 
TGTGGTGAGC GAGTAATTGT TGAGCATGCC CGCGGCCCAC GGCGAGATGG CAGTTACGGT 
TCTGGACGCA GTGGATATGG TTATAGAAGA AGTGGCCGAG ATAAATATGG CCCTCCTACT 
CGCACAGAGT ACAGACTTAT TGTGGAGAAT TTGTCAAGTC GGTGCAGCTG GCAAGACCTA 
AAGGATTATA TGCGTCAGGC AGGAGAAGTG ACTTATGCAG ATGCTCACAA GGGACGCAAA 
AATGAAGGGG TGATTGAATT TGTATCTTAT TCTGATATGA AAAGAGCTTT GGAAAAGTTG 
GATGGAACTG AAGTCAATGG GAGAAAAATC AGATTAGTTG AAGACAAGCC AGGTTCCAGA 
CGACGCCGGT CCTACTCCAG AAGCCGGAGT CATTCAAGGT CGGGCTCCCG CTCCCGGAGC 
AAGAGCCGGA GCCGGAGCCA GAGTCGGAGC CGGAGCAAGA AAGAGAAAAG CAGGAGCCCC 
AGCAAGGAAA AGAGCCGCAG CCGCAGCCAT AGCGCTGGCA AGAGCCGCAG CAAGAGCAAA 
GACCAAGCTG AAGAGAAGAT CCAAAACAAT GACAATGTCG GGAAACCCAA GAGCCGGAGT 
CCTAGCAGGC ATAAAAGTAA GAGCAAAAGT CGGAGCAGGA GTCAGGAGAG GAGAGTGGAG 
GAGGAGAAGC GAGGGAGTGT GAGCAGGGGC AGGAGCCAGG AGAAGAGCCT CCGCCAGAGT 
CGGAGCCGGA GCAGGAGCAA AGGGGGCAGC AGGAGCCGGA GCAGGAGCCG CAGCAAGAGC 
AAGGACAAGA GGAAGGGCAG GAAGAGAAGC AGAGAGGAGA GCCGCAGTCG CAGTCGCAGC 
CGCAGCAAGA GTGAGAGGAG CAGAAAGCGA GGCAGCAAGC GAGACAGCAA GGCGGGCAGC 
AGCAAGAAGA AGAAGAAGGA AGACACTGAC CGCTCCCAGT CCAGATCTCC ATCCCGCTCC 
GTGTCAAAGG AGCGGGAACA TGCCAAGTCT GAATCCAGCC AGAGGGAAGG TCGAGGAGAG 
AGTGAGAATG CTGGCACCAA TCAGGAGACC CGGTCCAGGT CGAGATCCAA TTCCAAATCG 
AAACCAAACC TTCCATCAGA ATCACGCTCC AGATCAAAGT CAGCTTCAAA AACCCGATCT 
CGGTCCAAGT CTAGATCCAG GTCTGCTTCC AGATCGCCCT CCCGATCTAG ATCTAGGTCC 
CACTCAAGGT CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis.
BMC cancer15227(2015 Apr)
Gabriel M,Delforge Y,Deward A,Habraken Y,Hennuy B,Piette J,Klinck R,Chabot B,Colige A,Lambert C

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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SRSF4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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