MS4A5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MS4A5
Entrez Gene ID	64232
Full Name	membrane spanning 4-domains A5
Synonyms	CD20-L2,CD20L2,TETM4
General protein information	Preferred Names membrane spanning 4-domains A5 Names membrane-spanning 4-domains subfamily A member 5 CD20 antigen-like 2 testis-expressed transmembrane protein 4 testis-expressed transmembrane-4 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q12.2
Summary	This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Though this member is not expressed in hematopoietic cells specifically, it may be involved in signal transduction like many of its related family members. The gene encoding this protein is localized to 11q12, among a cluster of family members. [provided by RefSeq, Jul 2008].
Disorder MIM:	606499

mRNA and Protein(s)

mRNA	Protein	Name
NM_023945.3	NP_076434.2	membrane-spanning 4-domains subfamily A member 5
NM_023945.2	NP_076434.2	membrane-spanning 4-domains subfamily A member 5

Pathways from BioSystems

Homologies

	MS4A5	XP_001086601.1
Mus musculus (house mouse)	Ms4a5	NP_899013.1
Pan troglodytes (chimpanzee)	MS4A5	XP_508460.1
Canis lupus familiaris (dog)	MS4A5	XP_855393.1
Bos taurus (cattle)	MS4A5	NP_001071614.1
Rattus norvegicus (Norway rat)	Ms4a5	XP_003749114.1
Homo sapiens (human)	MS4A5	NP_076434.2

Gene Ontology
Bibliography

Related articles in PubMed

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Structural organization of the human MS4A gene cluster on Chromosome 11q12.
Liang Y, Buckley TR, Tu L, Langdon SD, Tedder TF
Immunogenetics53(5)357-68(2001 Jul)

Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse.
Liang Y, Tedder TF
Genomics72(2)119-27(2001 Mar)

Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor.
Ishibashi K, Suzuki M, Sasaki S, Imai M
Gene264(1)87-93(2001 Feb)

Isolation, tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-beta.
Hulett MD, Pagler E, Hornby JR, Hogarth PM, Eyre HJ, Baker E, Crawford J, Sutherland GR, Ohms SJ, Parish CR
Biochemical and biophysical research communications280(1)374-9(2001 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

The following MS4A5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MS4A5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29432	NM_023945.3 Latest version!	Homo sapiens membrane spanning 4-domains A5 (MS4A5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29432	NM_023945.2	Homo sapiens membrane spanning 4-domains A5 (MS4A5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MS4A5 ( NM_023945.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_076434.2 Homo sapiens membrane spanning 4-domains A5 (MS4A5), mRNA.

Price & Availability↑

CloneID	OHu29432
Clone ID Related Accession (Same CDS sequence)	NM_023945.3 , NM_023945.2
Accession Version	NM_023945.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003127.2 and BC029884.1. On Nov 23, 2018 this sequence version replaced NM_023945.2. ##Evidence-Data-START## Transcript exon combination :: SRR5189667.131933.1, BI829760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000300190.7/ ENSP00000300190.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT 
TCAGAATATG AGTCCACAGA ACTTTCAGCC ACGACCTTTT CAACTCAAAG CCCCTTGCAA 
AAATTATTTG CTAGAAAAAT GAAAATCTTA GGGACTATCC AGATCCTGTT TGGAATTATG 
ACCTTTTCTT TTGGAGTTAT CTTCCTTTTC ACCTTGTTAA AACCATATCC AAGGTTTCCC 
TTTATATTTC TTTCAGGATA TCCATTCTGG GGCTCTGTTT TGTTCATTAA TTCTGGAGCC 
TTCCTAATTG CAGTGAAAAG AAAAACCACA GAAACTCTGA TAATATTGAG CCGAATAATG 
AATTTTCTTA GTGCCCTGGG AGCAATAGCT GGAATCATTC TCCTCACATT TGGTTTCATC 
CTAGATCAAA ACTACATTTG TGGTTATTCT CACCAAAATA GTCAGTGTAA GGCTGTTACT 
GTCCTGTTCT TGGGAATTTT GATTACATTG ATGACTTTCA GCATTATTGA ATTATTCATT 
TCTCTGCCTT TCTCAATTTT GGGGTGCCAC TCAGAGGATT GTGATTGTGA ACAATGTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076434.2
CDS	104..706
Translation	MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSILGCHSEDCDCEQCC

Target ORF information:

RefSeq Version	NM_023945.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A5 (MS4A5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023945.3

ORF Insert Sequence:

ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT 
TCAGAATATG AGTCCACAGA ACTTTCAGCC ACGACCTTTT CAACTCAAAG CCCCTTGCAA 
AAATTATTTG CTAGAAAAAT GAAAATCTTA GGGACTATCC AGATCCTGTT TGGAATTATG 
ACCTTTTCTT TTGGAGTTAT CTTCCTTTTC ACCTTGTTAA AACCATATCC AAGGTTTCCC 
TTTATATTTC TTTCAGGATA TCCATTCTGG GGCTCTGTTT TGTTCATTAA TTCTGGAGCC 
TTCCTAATTG CAGTGAAAAG AAAAACCACA GAAACTCTGA TAATATTGAG CCGAATAATG 
AATTTTCTTA GTGCCCTGGG AGCAATAGCT GGAATCATTC TCCTCACATT TGGTTTCATC 
CTAGATCAAA ACTACATTTG TGGTTATTCT CACCAAAATA GTCAGTGTAA GGCTGTTACT 
GTCCTGTTCT TGGGAATTTT GATTACATTG ATGACTTTCA GCATTATTGA ATTATTCATT 
TCTCTGCCTT TCTCAATTTT GGGGTGCCAC TCAGAGGATT GTGATTGTGA ACAATGTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MS4A5 ( NM_023945.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_076434.2 Homo sapiens membrane spanning 4-domains A5 (MS4A5), mRNA.

Price & Availability↑

CloneID	OHu29432
Clone ID Related Accession (Same CDS sequence)	NM_023945.3 , NM_023945.2
Accession Version	NM_023945.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	membrane-spanning 4-domains subfamily A member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC029884.1. On Sep 18, 2002 this sequence version replaced NM_023945.1. ##Evidence-Data-START## Transcript exon combination :: BC029884.1, BQ429208.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT 
TCAGAATATG AGTCCACAGA ACTTTCAGCC ACGACCTTTT CAACTCAAAG CCCCTTGCAA 
AAATTATTTG CTAGAAAAAT GAAAATCTTA GGGACTATCC AGATCCTGTT TGGAATTATG 
ACCTTTTCTT TTGGAGTTAT CTTCCTTTTC ACCTTGTTAA AACCATATCC AAGGTTTCCC 
TTTATATTTC TTTCAGGATA TCCATTCTGG GGCTCTGTTT TGTTCATTAA TTCTGGAGCC 
TTCCTAATTG CAGTGAAAAG AAAAACCACA GAAACTCTGA TAATATTGAG CCGAATAATG 
AATTTTCTTA GTGCCCTGGG AGCAATAGCT GGAATCATTC TCCTCACATT TGGTTTCATC 
CTAGATCAAA ACTACATTTG TGGTTATTCT CACCAAAATA GTCAGTGTAA GGCTGTTACT 
GTCCTGTTCT TGGGAATTTT GATTACATTG ATGACTTTCA GCATTATTGA ATTATTCATT 
TCTCTGCCTT TCTCAATTTT GGGGTGCCAC TCAGAGGATT GTGATTGTGA ACAATGTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_076434.2
CDS	87..689
Translation	MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSILGCHSEDCDCEQCC

Target ORF information:

RefSeq Version	NM_023945.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane spanning 4-domains A5 (MS4A5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_023945.2

ORF Insert Sequence:

ATGGATTCAA GCACCGCACA CAGTCCGGTG TTTCTGGTAT TTCCTCCAGA AATCACTGCT 
TCAGAATATG AGTCCACAGA ACTTTCAGCC ACGACCTTTT CAACTCAAAG CCCCTTGCAA 
AAATTATTTG CTAGAAAAAT GAAAATCTTA GGGACTATCC AGATCCTGTT TGGAATTATG 
ACCTTTTCTT TTGGAGTTAT CTTCCTTTTC ACCTTGTTAA AACCATATCC AAGGTTTCCC 
TTTATATTTC TTTCAGGATA TCCATTCTGG GGCTCTGTTT TGTTCATTAA TTCTGGAGCC 
TTCCTAATTG CAGTGAAAAG AAAAACCACA GAAACTCTGA TAATATTGAG CCGAATAATG 
AATTTTCTTA GTGCCCTGGG AGCAATAGCT GGAATCATTC TCCTCACATT TGGTTTCATC 
CTAGATCAAA ACTACATTTG TGGTTATTCT CACCAAAATA GTCAGTGTAA GGCTGTTACT 
GTCCTGTTCT TGGGAATTTT GATTACATTG ATGACTTTCA GCATTATTGA ATTATTCATT 
TCTCTGCCTT TCTCAATTTT GGGGTGCCAC TCAGAGGATT GTGATTGTGA ACAATGTTGT 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Structural organization of the human MS4A gene cluster on Chromosome 11q12.
Immunogenetics53(5)357-68(2001 Jul)
Liang Y,Buckley TR,Tu L,Langdon SD,Tedder TF

Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse.
Genomics72(2)119-27(2001 Mar)
Liang Y,Tedder TF

Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor.
Gene264(1)87-93(2001 Feb)
Ishibashi K,Suzuki M,Sasaki S,Imai M

Isolation, tissue distribution, and chromosomal localization of a novel testis-specific human four-transmembrane gene related to CD20 and FcepsilonRI-beta.
Biochemical and biophysical research communications280(1)374-9(2001 Jan)
Hulett MD,Pagler E,Hornby JR,Hogarth PM,Eyre HJ,Baker E,Crawford J,Sutherland GR,Ohms SJ,Parish CR

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MS4A5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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