BLMH cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BLMH
Entrez Gene ID	642
Full Name	bleomycin hydrolase
Synonyms	BH,BMH
General protein information	Preferred Names bleomycin hydrolase Names bleomycin hydrolase BLM hydrolase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2
Summary	Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008].
Disorder MIM:	602403

mRNA and Protein(s)

mRNA	Protein	Name
NM_000386.3	NP_000377.1	bleomycin hydrolase
NM_000386.4	NP_000377.1	bleomycin hydrolase

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BLMH	XP_002695724.3
Mus musculus (house mouse)	Blmh	NP_848760.1
Rattus norvegicus (Norway rat)	Blmh	NP_001029335.1
Drosophila melanogaster (fruit fly)	CG1440	NP_001096907.1
Eremothecium gossypii	AGOS_ABL204W	NP_982743.1
Neurospora crassa	NCU08333	XP_965236.2
	BLMH	XP_002800396.1
Canis lupus familiaris (dog)	BLMH	XP_537755.3
Gallus gallus (chicken)	BLMH	NP_990435.1
Homo sapiens (human)	BLMH	NP_000377.1
Pan troglodytes (chimpanzee)	BLMH	XP_511383.3
Danio rerio (zebrafish)	blmh	NP_956312.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001341	XP_321804.3
Saccharomyces cerevisiae (baker's yeast)	LAP3	NP_014160.2
Magnaporthe oryzae (rice blast fungus)	MGG_02695	XP_003721070.1
Xenopus tropicalis (tropical clawed frog)	blmh	NP_001006900.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents.
Chen Y, Zhang H, He Q
International journal of oncology50(1)223-231(2017 Jan)

An inter-species protein-protein interaction network across vast evolutionary distance.
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Ta?an M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barab?si AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M
Molecular systems biology12(4)865(2016 Apr)

Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.
J?na ?, Milt?nyi Z, P?liska S, B?lint BL, Ill?s ?
PloS one11(6)e0157651(2016)

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ubc9 plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase and poly(ADP-ribose) polymerase-1. The results are beneficial to deeply understanding of Ubc9 functions and for precise prediction of chemotherapy outcomes in tumors.
Title: Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents.

the BLMH gene single nucleotide polymorphism A1450G (rs1050565) influences BLMH activity and late pulmonary toxicity.
Title: Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.

Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of filaggrin gene mutations
Title: Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.

We also detected significant association between XRCC1, XRCC3, and BLHX polymorphisms and a high frequency of chromosomal damage
Title: Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer.

This study findings suggest that Blmh interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis.
Title: Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration.

The following BLMH gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BLMH cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19087	NM_000386.4 Latest version!	Homo sapiens bleomycin hydrolase (BLMH), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu19087	NM_000386.3	Homo sapiens bleomycin hydrolase (BLMH), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BLMH ( NM_000386.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000377.1 Homo sapiens bleomycin hydrolase (BLMH), mRNA.

Price & Availability↑

CloneID	OHu19087
Clone ID Related Accession (Same CDS sequence)	NM_000386.3 , NM_000386.4
Accession Version	NM_000386.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	bleomycin hydrolase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC346179.1, BC003616.2 and AI283058.1. This sequence is a reference standard in the RefSeqGene project. On Jan 7, 2011 this sequence version replaced NM_000386.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.246089.1, SRR1660803.139878.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGCAGCT CGGGACTGAA TTCGGAGAAG GTAGCTGCTC TGATACAGAA ACTGAATTCC 
GACCCCCAGT TCGTACTTGC CCAGAATGTC GGGACCACCC ACGACCTGCT GGACATCTGT 
CTGAAGCGGG CCACGGTGCA GCGCGCGCAG CATGTGTTCC AGCACGCCGT GCCCCAGGAG 
GGCAAGCCAA TCACCAACCA GAAGAGCTCA GGGCGATGCT GGATCTTTTC TTGTCTGAAT 
GTTATGAGGC TTCCATTCAT GAAAAAGTTA AATATTGAAG AATTTGAGTT TAGCCAATCT 
TACCTGTTTT TTTGGGACAA GGTTGAACGC TGTTATTTCT TCTTGAGTGC TTTTGTGGAC 
ACAGCCCAGA GAAAGGAGCC TGAGGATGGG AGGCTGGTGC AGTTTTTGCT TATGAACCCT 
GCAAATGATG GTGGCCAATG GGATATGCTT GTTAATATTG TTGAAAAATA TGGTGTTATC 
CCTAAGAAAT GCTTCCCTGA ATCTTATACA ACAGAGGCAA CCAGAAGGAT GAATGATATT 
CTGAATCACA AGATGAGAGA ATTCTGTATA CGACTGCGGA ACCTGGTACA CAGTGGAGCA 
ACCAAAGGAG AAATCTCGGC CACACAGGAC GTCATGATGG AGGAGATATT CCGAGTGGTG 
TGCATCTGTT TGGGTAATCC ACCAGAGACA TTCACCTGGG AATATCGAGA CAAAGATAAA 
AATTATCAGA AAATTGGCCC CATAACACCC TTGGAGTTTT ACAGGGAACA TGTCAAGCCA 
CTCTTCAATA TGGAAGATAA GATTTGTTTA GTGAATGACC CTAGGCCCCA GCACAAGTAC 
AACAAACTTT ACACAGTGGA ATACTTAAGC AATATGGTTG GAGGGAGAAA AACTCTATAC 
AACAACCAGC CCATTGACTT CCTGAAAAAG ATGGTTGCTG CCTCCATCAA AGATGGAGAG 
GCTGTGTGGT TTGGCTGTGA TGTTGGAAAA CACTTCAATA GCAAGCTGGG CCTCAGTGAC 
ATGAATCTCT ATGACCATGA GTTAGTGTTT GGTGTCTCCT TGAAGAACAT GAATAAAGCG 
GAGAGGCTGA CTTTTGGTGA GTCACTTATG ACCCACGCCA TGACCTTCAC TGCTGTCTCA 
GAGAAGGATG ATCAGGATGG TGCTTTCACA AAATGGAGAG TGGAGAATTC ATGGGGTGAA 
GACCATGGCC ACAAAGGTTA CCTGTGCATG ACAGATGAGT GGTTCTCTGA GTATGTCTAC 
GAAGTGGTGG TGGACAGGAA GCATGTCCCT GAAGAGGTGC TAGCTGTGTT AGAGCAGGAA 
CCCATTATCC TGCCAGCATG GGACCCCATG GGAGCTTTGG CTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000377.1
CDS	348..1715
Translation	MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE

Target ORF information:

RefSeq Version	NM_000386.3
Organism	Homo sapiens(human)
Definition	Homo sapiens bleomycin hydrolase (BLMH), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000386.3

ORF Insert Sequence:

ATGAGCAGCT CGGGACTGAA TTCGGAGAAG GTAGCTGCTC TGATACAGAA ACTGAATTCC 
GACCCCCAGT TCGTACTTGC CCAGAATGTC GGGACCACCC ACGACCTGCT GGACATCTGT 
CTGAAGCGGG CCACGGTGCA GCGCGCGCAG CATGTGTTCC AGCACGCCGT GCCCCAGGAG 
GGCAAGCCAA TCACCAACCA GAAGAGCTCA GGGCGATGCT GGATCTTTTC TTGTCTGAAT 
GTTATGAGGC TTCCATTCAT GAAAAAGTTA AATATTGAAG AATTTGAGTT TAGCCAATCT 
TACCTGTTTT TTTGGGACAA GGTTGAACGC TGTTATTTCT TCTTGAGTGC TTTTGTGGAC 
ACAGCCCAGA GAAAGGAGCC TGAGGATGGG AGGCTGGTGC AGTTTTTGCT TATGAACCCT 
GCAAATGATG GTGGCCAATG GGATATGCTT GTTAATATTG TTGAAAAATA TGGTGTTATC 
CCTAAGAAAT GCTTCCCTGA ATCTTATACA ACAGAGGCAA CCAGAAGGAT GAATGATATT 
CTGAATCACA AGATGAGAGA ATTCTGTATA CGACTGCGGA ACCTGGTACA CAGTGGAGCA 
ACCAAAGGAG AAATCTCGGC CACACAGGAC GTCATGATGG AGGAGATATT CCGAGTGGTG 
TGCATCTGTT TGGGTAATCC ACCAGAGACA TTCACCTGGG AATATCGAGA CAAAGATAAA 
AATTATCAGA AAATTGGCCC CATAACACCC TTGGAGTTTT ACAGGGAACA TGTCAAGCCA 
CTCTTCAATA TGGAAGATAA GATTTGTTTA GTGAATGACC CTAGGCCCCA GCACAAGTAC 
AACAAACTTT ACACAGTGGA ATACTTAAGC AATATGGTTG GAGGGAGAAA AACTCTATAC 
AACAACCAGC CCATTGACTT CCTGAAAAAG ATGGTTGCTG CCTCCATCAA AGATGGAGAG 
GCTGTGTGGT TTGGCTGTGA TGTTGGAAAA CACTTCAATA GCAAGCTGGG CCTCAGTGAC 
ATGAATCTCT ATGACCATGA GTTAGTGTTT GGTGTCTCCT TGAAGAACAT GAATAAAGCG 
GAGAGGCTGA CTTTTGGTGA GTCACTTATG ACCCACGCCA TGACCTTCAC TGCTGTCTCA 
GAGAAGGATG ATCAGGATGG TGCTTTCACA AAATGGAGAG TGGAGAATTC ATGGGGTGAA 
GACCATGGCC ACAAAGGTTA CCTGTGCATG ACAGATGAGT GGTTCTCTGA GTATGTCTAC 
GAAGTGGTGG TGGACAGGAA GCATGTCCCT GAAGAGGTGC TAGCTGTGTT AGAGCAGGAA 
CCCATTATCC TGCCAGCATG GGACCCCATG GGAGCTTTGG CTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLMH ( NM_000386.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000377.1 Homo sapiens bleomycin hydrolase (BLMH), mRNA.

Price & Availability↑

CloneID	OHu19087
Clone ID Related Accession (Same CDS sequence)	NM_000386.3 , NM_000386.4
Accession Version	NM_000386.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	bleomycin hydrolase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC346179.1 and BC003616.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000386.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.224542.1, SRR1163658.220035.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261714.11/ ENSP00000261714.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCAGCT CGGGACTGAA TTCGGAGAAG GTAGCTGCTC TGATACAGAA ACTGAATTCC 
GACCCCCAGT TCGTACTTGC CCAGAATGTC GGGACCACCC ACGACCTGCT GGACATCTGT 
CTGAAGCGGG CCACGGTGCA GCGCGCGCAG CATGTGTTCC AGCACGCCGT GCCCCAGGAG 
GGCAAGCCAA TCACCAACCA GAAGAGCTCA GGGCGATGCT GGATCTTTTC TTGTCTGAAT 
GTTATGAGGC TTCCATTCAT GAAAAAGTTA AATATTGAAG AATTTGAGTT TAGCCAATCT 
TACCTGTTTT TTTGGGACAA GGTTGAACGC TGTTATTTCT TCTTGAGTGC TTTTGTGGAC 
ACAGCCCAGA GAAAGGAGCC TGAGGATGGG AGGCTGGTGC AGTTTTTGCT TATGAACCCT 
GCAAATGATG GTGGCCAATG GGATATGCTT GTTAATATTG TTGAAAAATA TGGTGTTATC 
CCTAAGAAAT GCTTCCCTGA ATCTTATACA ACAGAGGCAA CCAGAAGGAT GAATGATATT 
CTGAATCACA AGATGAGAGA ATTCTGTATA CGACTGCGGA ACCTGGTACA CAGTGGAGCA 
ACCAAAGGAG AAATCTCGGC CACACAGGAC GTCATGATGG AGGAGATATT CCGAGTGGTG 
TGCATCTGTT TGGGTAATCC ACCAGAGACA TTCACCTGGG AATATCGAGA CAAAGATAAA 
AATTATCAGA AAATTGGCCC CATAACACCC TTGGAGTTTT ACAGGGAACA TGTCAAGCCA 
CTCTTCAATA TGGAAGATAA GATTTGTTTA GTGAATGACC CTAGGCCCCA GCACAAGTAC 
AACAAACTTT ACACAGTGGA ATACTTAAGC AATATGGTTG GAGGGAGAAA AACTCTATAC 
AACAACCAGC CCATTGACTT CCTGAAAAAG ATGGTTGCTG CCTCCATCAA AGATGGAGAG 
GCTGTGTGGT TTGGCTGTGA TGTTGGAAAA CACTTCAATA GCAAGCTGGG CCTCAGTGAC 
ATGAATCTCT ATGACCATGA GTTAGTGTTT GGTGTCTCCT TGAAGAACAT GAATAAAGCG 
GAGAGGCTGA CTTTTGGTGA GTCACTTATG ACCCACGCCA TGACCTTCAC TGCTGTCTCA 
GAGAAGGATG ATCAGGATGG TGCTTTCACA AAATGGAGAG TGGAGAATTC ATGGGGTGAA 
GACCATGGCC ACAAAGGTTA CCTGTGCATG ACAGATGAGT GGTTCTCTGA GTATGTCTAC 
GAAGTGGTGG TGGACAGGAA GCATGTCCCT GAAGAGGTGC TAGCTGTGTT AGAGCAGGAA 
CCCATTATCC TGCCAGCATG GGACCCCATG GGAGCTTTGG CTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000377.1
CDS	126..1493
Translation	MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVDTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE

Target ORF information:

RefSeq Version	NM_000386.4
Organism	Homo sapiens(human)
Definition	Homo sapiens bleomycin hydrolase (BLMH), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000386.4

ORF Insert Sequence:

ATGAGCAGCT CGGGACTGAA TTCGGAGAAG GTAGCTGCTC TGATACAGAA ACTGAATTCC 
GACCCCCAGT TCGTACTTGC CCAGAATGTC GGGACCACCC ACGACCTGCT GGACATCTGT 
CTGAAGCGGG CCACGGTGCA GCGCGCGCAG CATGTGTTCC AGCACGCCGT GCCCCAGGAG 
GGCAAGCCAA TCACCAACCA GAAGAGCTCA GGGCGATGCT GGATCTTTTC TTGTCTGAAT 
GTTATGAGGC TTCCATTCAT GAAAAAGTTA AATATTGAAG AATTTGAGTT TAGCCAATCT 
TACCTGTTTT TTTGGGACAA GGTTGAACGC TGTTATTTCT TCTTGAGTGC TTTTGTGGAC 
ACAGCCCAGA GAAAGGAGCC TGAGGATGGG AGGCTGGTGC AGTTTTTGCT TATGAACCCT 
GCAAATGATG GTGGCCAATG GGATATGCTT GTTAATATTG TTGAAAAATA TGGTGTTATC 
CCTAAGAAAT GCTTCCCTGA ATCTTATACA ACAGAGGCAA CCAGAAGGAT GAATGATATT 
CTGAATCACA AGATGAGAGA ATTCTGTATA CGACTGCGGA ACCTGGTACA CAGTGGAGCA 
ACCAAAGGAG AAATCTCGGC CACACAGGAC GTCATGATGG AGGAGATATT CCGAGTGGTG 
TGCATCTGTT TGGGTAATCC ACCAGAGACA TTCACCTGGG AATATCGAGA CAAAGATAAA 
AATTATCAGA AAATTGGCCC CATAACACCC TTGGAGTTTT ACAGGGAACA TGTCAAGCCA 
CTCTTCAATA TGGAAGATAA GATTTGTTTA GTGAATGACC CTAGGCCCCA GCACAAGTAC 
AACAAACTTT ACACAGTGGA ATACTTAAGC AATATGGTTG GAGGGAGAAA AACTCTATAC 
AACAACCAGC CCATTGACTT CCTGAAAAAG ATGGTTGCTG CCTCCATCAA AGATGGAGAG 
GCTGTGTGGT TTGGCTGTGA TGTTGGAAAA CACTTCAATA GCAAGCTGGG CCTCAGTGAC 
ATGAATCTCT ATGACCATGA GTTAGTGTTT GGTGTCTCCT TGAAGAACAT GAATAAAGCG 
GAGAGGCTGA CTTTTGGTGA GTCACTTATG ACCCACGCCA TGACCTTCAC TGCTGTCTCA 
GAGAAGGATG ATCAGGATGG TGCTTTCACA AAATGGAGAG TGGAGAATTC ATGGGGTGAA 
GACCATGGCC ACAAAGGTTA CCTGTGCATG ACAGATGAGT GGTTCTCTGA GTATGTCTAC 
GAAGTGGTGG TGGACAGGAA GCATGTCCCT GAAGAGGTGC TAGCTGTGTT AGAGCAGGAA 
CCCATTATCC TGCCAGCATG GGACCCCATG GGAGCTTTGG CTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents.
International journal of oncology50(1)223-231(2017 Jan)
Chen Y,Zhang H,He Q

An inter-species protein-protein interaction network across vast evolutionary distance.
Molecular systems biology12(4)865(2016 Apr)
Zhong Q,Pevzner SJ,Hao T,Wang Y,Mosca R,Menche J,Taipale M,Ta?an M,Fan C,Yang X,Haley P,Murray RR,Mer F,Gebreab F,Tam S,MacWilliams A,Dricot A,Reichert P,Santhanam B,Ghamsari L,Calderwood MA,Rolland T,Charloteaux B,Lindquist S,Barab?si AL,Hill DE,Aloy P,Cusick ME,Xia Y,Roth FP,Vidal M

Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.
PloS one11(6)e0157651(2016)
J?na ?,Milt?nyi Z,P?liska S,B?lint BL,Ill?s ?

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

BLMH cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報