DPEP3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DPEP3
Entrez Gene ID	64180
Full Name	dipeptidase 3
Synonyms	MBD3
General protein information	Preferred Names dipeptidase 3 Names dipeptidase 3 membrane-bound dipeptidase 3 metallopeptidase (family M19) testis secretory sperm-binding protein Li 211a
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Summary	This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	609926

mRNA and Protein(s)

mRNA	Protein	Name
NM_022357.3	NP_071752.3	dipeptidase 3 isoform a precursor
NM_001129758.1	NP_001123230.1	dipeptidase 3 isoform b precursor
NM_001129758.2	NP_001123230.2	dipeptidase 3 isoform b precursor
NM_022357.4	NP_071752.3	dipeptidase 3 isoform a precursor
NM_001370198.1	NP_001357127.1	dipeptidase 3 isoform c precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	DPEP3	XP_005620859.1
Danio rerio (zebrafish)	LOC100534995	XP_003199021.2
	DPEP3	XP_001096561.1
Rattus norvegicus (Norway rat)	Dpep3	NP_001008384.1
Homo sapiens (human)	DPEP3	NP_071752.3
Pan troglodytes (chimpanzee)	DPEP3	XP_523398.3
Mus musculus (house mouse)	Dpep3	NP_082236.1
Bos taurus (cattle)	DPEP3	XP_002694950.1
Drosophila melanogaster (fruit fly)	CG34420	NP_648516.2

Gene Ontology
Bibliography

Related articles in PubMed

Biological insights from 108 schizophrenia-associated genetic loci.

Nature511(7510)421-7(2014 Jul)

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
Sabatti C, Service SK, Hartikainen AL, Pouta A, Ripatti S, Brodsky J, Jones CG, Zaitlen NA, Varilo T, Kaakinen M, Sovio U, Ruokonen A, Laitinen J, Jakkula E, Coin L, Hoggart C, Collins A, Turunen H, Gabriel S, Elliot P, McCarthy MI, Daly MJ, J?rvelin MR, Freimer NB, Peltonen L
Nature genetics41(1)35-46(2009 Jan)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

Identification of two additional members of the membrane-bound dipeptidase family.
Habib GM, Shi ZZ, Cuevas AA, Lieberman MW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology17(10)1313-5(2003 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This paper describes differences in substrate specificity and tissue distribution of membrane-bound dipeptidase 3 from mouse in comparison to other mouse members of this family.
Title: Identification of two additional members of the membrane-bound dipeptidase family.

The following DPEP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DPEP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31532	NM_022357.4 Latest version!	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu06904	NM_001129758.1 Latest version!	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu108549	NM_001370198.1 Latest version!	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu108553	NM_001129758.2 Latest version!	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu31532	NM_022357.3	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DPEP3 ( NM_022357.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071752.3 Homo sapiens dipeptidase 3 (DPEP3), transcript variant 1, mRNA.

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CloneID	OHu31532
Clone ID Related Accession (Same CDS sequence)	NM_022357.3 , NM_022357.4
Accession Version	NM_022357.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-21
Organism	Homo sapiens(human)
Product	dipeptidase 3 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK057401.1 and AJ291679.1. On Nov 22, 2018 this sequence version replaced NM_022357.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). CCDS Note: The translation start codon selected for this CCDS is conserved in primates. A possible downstream translation start codon, which is better conserved across species and is consistent with the dipeptidase 2 family member, would reduce the protein length by 25 aa. No experimental evidence exists regarding which start codon is used. ##Evidence-Data-START## Transcript exon combination :: AJ291679.1, AK057401.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGATCCGGA CCCCATTGTC GGCCTCTGCC CATCGCCTGC TCCTCCCAGG CTCCCGCGGC 
CGACCCCCGC GCAACATGCA GCCCACGGGC CGCGAGGGTT CCCGCGCGCT CAGCCGGCGG 
TATCTGCGGC GTCTGCTGCT CCTGCTACTG CTGCTGCTGC TGCGGCAGCC CGTAACCCGC 
GCGGAGACCA CGCCGGGCGC CCCCAGAGCC CTCTCCACGC TGGGCTCCCC CAGCCTCTTC 
ACCACGCCGG GTGTCCCCAG CGCCCTCACT ACCCCAGGCC TCACTACGCC AGGCACCCCC 
AAAACCCTGG ACCTTCGGGG TCGCGCGCAG GCCCTGATGC GGAGTTTCCC ACTCGTGGAC 
GGCCACAATG ACCTGCCCCA GGTCCTGAGA CAGCGTTACA AGAATGTGCT TCAGGATGTT 
AACCTGCGAA ATTTCAGCCA TGGTCAGACC AGCCTGGACA GGCTTAGAGA CGGCCTCGTG 
GGTGCCCAGT TCTGGTCAGC CTCCGTCTCA TGCCAGTCCC AGGACCAGAC TGCCGTGCGC 
CTCGCCCTGG AGCAGATTGA CCTCATTCAC CGCATGTGTG CCTCCTACTC TGAACTCGAG 
CTTGTGACCT CAGCTGAAGG TCTGAACAGC TCTCAAAAGC TGGCCTGCCT CATTGGCGTG 
GAGGGTGGTC ACTCACTGGA CAGCAGCCTC TCTGTGCTGC GCAGTTTCTA TGTGCTGGGG 
GTGCGCTACC TGACACTTAC CTTCACCTGC AGTACACCAT GGGCAGAGAG TTCCACCAAG 
TTCAGACACC ACATGTACAC CAACGTCAGC GGATTGACAA GCTTTGGTGA GAAAGTAGTA 
GAGGAGTTGA ACCGCCTGGG CATGATGATA GATTTGTCCT ATGCATCGGA CACCTTGATA 
AGAAGGGTCC TGGAAGTGTC TCAGGCTCCT GTGATCTTCT CCCACTCAGC TGCCAGAGCT 
GTGTGTGACA ATTTGTTGAA TGTTCCCGAT GATATCCTGC AGCTTCTGAA GAAGAACGGT 
GGCATCGTGA TGGTGACACT GTCCATGGGG GTGCTGCAGT GCAACCTGCT TGCTAACGTG 
TCCACTGTGG CAGATCACTT TGACCACATC AGGGCAGTCA TTGGATCTGA GTTCATCGGG 
ATTGGTGGAA ATTATGACGG GACTGGCCGG TTCCCTCAGG GGCTGGAGGA TGTGTCCACA 
TACCCAGTCC TGATAGAGGA GTTGCTGAGT CGTAGCTGGA GCGAGGAAGA GCTTCAAGGT 
GTCCTTCGTG GAAACCTGCT GCGGGTCTTC AGACAAGTGG AAAAGGTGAG AGAGGAGAGC 
AGGGCGCAGA GCCCCGTGGA GGCTGAGTTT CCATATGGGC AACTGAGCAC ATCCTGCCAC 
TCCCACCTCG TGCCTCAGAA TGGACACCAG GCTACTCATC TGGAGGTGAC CAAGCAGCCA 
ACCAATCGGG TCCCCTGGAG GTCCTCAAAT GCCTCCCCAT ACCTTGTTCC AGGCCTTGTG 
GCTGCTGCCA CCATCCCAAC CTTCACCCAG TGGCTCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071752.3
CDS	45..1586
Translation	MIRTPLSASAHRLLLPGSRGRPPRNMQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGVPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSPVEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATIPTFTQWLC

Target ORF information:

RefSeq Version	NM_022357.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022357.4

ORF Insert Sequence:

ATGATCCGGA CCCCATTGTC GGCCTCTGCC CATCGCCTGC TCCTCCCAGG CTCCCGCGGC 
CGACCCCCGC GCAACATGCA GCCCACGGGC CGCGAGGGTT CCCGCGCGCT CAGCCGGCGG 
TATCTGCGGC GTCTGCTGCT CCTGCTACTG CTGCTGCTGC TGCGGCAGCC CGTAACCCGC 
GCGGAGACCA CGCCGGGCGC CCCCAGAGCC CTCTCCACGC TGGGCTCCCC CAGCCTCTTC 
ACCACGCCGG GTGTCCCCAG CGCCCTCACT ACCCCAGGCC TCACTACGCC AGGCACCCCC 
AAAACCCTGG ACCTTCGGGG TCGCGCGCAG GCCCTGATGC GGAGTTTCCC ACTCGTGGAC 
GGCCACAATG ACCTGCCCCA GGTCCTGAGA CAGCGTTACA AGAATGTGCT TCAGGATGTT 
AACCTGCGAA ATTTCAGCCA TGGTCAGACC AGCCTGGACA GGCTTAGAGA CGGCCTCGTG 
GGTGCCCAGT TCTGGTCAGC CTCCGTCTCA TGCCAGTCCC AGGACCAGAC TGCCGTGCGC 
CTCGCCCTGG AGCAGATTGA CCTCATTCAC CGCATGTGTG CCTCCTACTC TGAACTCGAG 
CTTGTGACCT CAGCTGAAGG TCTGAACAGC TCTCAAAAGC TGGCCTGCCT CATTGGCGTG 
GAGGGTGGTC ACTCACTGGA CAGCAGCCTC TCTGTGCTGC GCAGTTTCTA TGTGCTGGGG 
GTGCGCTACC TGACACTTAC CTTCACCTGC AGTACACCAT GGGCAGAGAG TTCCACCAAG 
TTCAGACACC ACATGTACAC CAACGTCAGC GGATTGACAA GCTTTGGTGA GAAAGTAGTA 
GAGGAGTTGA ACCGCCTGGG CATGATGATA GATTTGTCCT ATGCATCGGA CACCTTGATA 
AGAAGGGTCC TGGAAGTGTC TCAGGCTCCT GTGATCTTCT CCCACTCAGC TGCCAGAGCT 
GTGTGTGACA ATTTGTTGAA TGTTCCCGAT GATATCCTGC AGCTTCTGAA GAAGAACGGT 
GGCATCGTGA TGGTGACACT GTCCATGGGG GTGCTGCAGT GCAACCTGCT TGCTAACGTG 
TCCACTGTGG CAGATCACTT TGACCACATC AGGGCAGTCA TTGGATCTGA GTTCATCGGG 
ATTGGTGGAA ATTATGACGG GACTGGCCGG TTCCCTCAGG GGCTGGAGGA TGTGTCCACA 
TACCCAGTCC TGATAGAGGA GTTGCTGAGT CGTAGCTGGA GCGAGGAAGA GCTTCAAGGT 
GTCCTTCGTG GAAACCTGCT GCGGGTCTTC AGACAAGTGG AAAAGGTGAG AGAGGAGAGC 
AGGGCGCAGA GCCCCGTGGA GGCTGAGTTT CCATATGGGC AACTGAGCAC ATCCTGCCAC 
TCCCACCTCG TGCCTCAGAA TGGACACCAG GCTACTCATC TGGAGGTGAC CAAGCAGCCA 
ACCAATCGGG TCCCCTGGAG GTCCTCAAAT GCCTCCCCAT ACCTTGTTCC AGGCCTTGTG 
GCTGCTGCCA CCATCCCAAC CTTCACCCAG TGGCTCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPEP3 ( NM_001129758.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001123230.1 Homo sapiens dipeptidase 3 (DPEP3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06904
Clone ID Related Accession (Same CDS sequence)	NM_001129758.1
Accession Version	NM_001129758.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	dipeptidase 3 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK057401.1, AY358390.1 and AJ291679.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: HM005556.1, AY358390.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCCGGA CCCCATTGTC GGCCTCTGCC CATCGCCTGC TCCTCCCAGG CTCCCGCGGC 
CGACCCCCGC GCAACATGCA GCCCACGGGC CGCGAGGGTT CCCGCGCGCT CAGCCGGCGG 
TATCTGCGGC GTCTGCTGCT CCTGCTACTG CTGCTGCTGC TGCGGCAGCC CGTAACCCGC 
GCGGAGACCA CGCCGGGCGC CCCCAGAGCC CTCTCCACGC TGGGCTCCCC CAGCCTCTTC 
ACCACGCCGG GTGTCCCCAG CGCCCTCACT ACCCCAGGCC TCACTACGCC AGGCACCCCC 
AAAACCCTGG ACCTTCGGGG TCGCGCGCAG GCCCTGATGC GGAGTTTCCC ACTCGTGGAC 
GGCCACAATG ACCTGCCCCA GGTCCTGAGA CAGCGTTACA AGAATGTGCT TCAGGATGTT 
AACCTGCGAA ATTTCAGCCA TGGTCAGACC AGCCTGGACA GGCTTAGAGA CGGCCTCGTG 
GGTGCCCAGT TCTGGTCAGC CTCCGTCTCA TGCCAGTCCC AGGACCAGAC TGCCGTGCGC 
CTCGCCCTGG AGCAGATTGA CCTCATTCAC CGCATGTGTG CCTCCTACTC TGAACTCGAG 
CTTGTGACCT CAGCTGAAGG TCTGAACAGC TCTCAAAAGC TGGCCTGCCT CATTGGCGTG 
GAGGGTGGTC ACTCACTGGA CAGCAGCCTC TCTGTGCTGC GCAGTTTCTA TGTGCTGGGG 
GTGCGCTACC TGACACTTAC CTTCACCTGC AGTACACCAT GGGCAGAGAG TTCCACCAAG 
TTCAGACACC ACATGTACAC CAACGTCAGC GGATTGACAA GCTTTGGTGA GAAAGTAGTA 
GAGGAGTTGA ACCGCCTGGG CATGATGATA GATTTGTCCT ATGCATCGGA CACCTTGATA 
AGAAGGGTCC TGGAAGTGTC TCAGGCTCCT GTGATCTTCT CCCACTCAGC TGCCAGAGCT 
GTGTGTGACA ATTTGTTGAA TGTTCCCGAT GATATCCTGC AGCTTCTGAA GAACGGTGGC 
ATCGTGATGG TGACACTGTC CATGGGGGTG CTGCAGTGCA ACCTGCTTGC TAACGTGTCC 
ACTGTGGCAG ATCACTTTGA CCACATCAGG GCAGTCATTG GATCTGAGTT CATCGGGATT 
GGTGGAAATT ATGACGGGAC TGGCCGGTTC CCTCAGGGGC TGGAGGATGT GTCCACATAC 
CCAGTCCTGA TAGAGGAGTT GCTGAGTCGT AGCTGGAGCG AGGAAGAGCT TCAAGGTGTC 
CTTCGTGGAA ACCTGCTGCG GGTCTTCAGA CAAGTGGAAA AGGTGAGAGA GGAGAGCAGG 
GCGCAGAGCC CCGTGGAGGC TGAGTTTCCA TATGGGCAAC TGAGCACATC CTGCCACTCC 
CACCTCGTGC CTCAGAATGG ACACCAGGCT ACTCATCTGG AGGTGACCAA GCAGCCAACC 
AATCGGGTCC CCTGGAGGTC CTCAAATGCC TCCCCATACC TTGTTCCAGG CCTTGTGGCT 
GCTGCCACCA TCCCAACCTT CACCCAGTGG CTCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123230.1
CDS	95..1633
Translation	MIRTPLSASAHRLLLPGSRGRPPRNMQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGVPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSPVEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATIPTFTQWLC

Target ORF information:

RefSeq Version	NM_001129758.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129758.1

ORF Insert Sequence:

ATGATCCGGA CCCCATTGTC GGCCTCTGCC CATCGCCTGC TCCTCCCAGG CTCCCGCGGC 
CGACCCCCGC GCAACATGCA GCCCACGGGC CGCGAGGGTT CCCGCGCGCT CAGCCGGCGG 
TATCTGCGGC GTCTGCTGCT CCTGCTACTG CTGCTGCTGC TGCGGCAGCC CGTAACCCGC 
GCGGAGACCA CGCCGGGCGC CCCCAGAGCC CTCTCCACGC TGGGCTCCCC CAGCCTCTTC 
ACCACGCCGG GTGTCCCCAG CGCCCTCACT ACCCCAGGCC TCACTACGCC AGGCACCCCC 
AAAACCCTGG ACCTTCGGGG TCGCGCGCAG GCCCTGATGC GGAGTTTCCC ACTCGTGGAC 
GGCCACAATG ACCTGCCCCA GGTCCTGAGA CAGCGTTACA AGAATGTGCT TCAGGATGTT 
AACCTGCGAA ATTTCAGCCA TGGTCAGACC AGCCTGGACA GGCTTAGAGA CGGCCTCGTG 
GGTGCCCAGT TCTGGTCAGC CTCCGTCTCA TGCCAGTCCC AGGACCAGAC TGCCGTGCGC 
CTCGCCCTGG AGCAGATTGA CCTCATTCAC CGCATGTGTG CCTCCTACTC TGAACTCGAG 
CTTGTGACCT CAGCTGAAGG TCTGAACAGC TCTCAAAAGC TGGCCTGCCT CATTGGCGTG 
GAGGGTGGTC ACTCACTGGA CAGCAGCCTC TCTGTGCTGC GCAGTTTCTA TGTGCTGGGG 
GTGCGCTACC TGACACTTAC CTTCACCTGC AGTACACCAT GGGCAGAGAG TTCCACCAAG 
TTCAGACACC ACATGTACAC CAACGTCAGC GGATTGACAA GCTTTGGTGA GAAAGTAGTA 
GAGGAGTTGA ACCGCCTGGG CATGATGATA GATTTGTCCT ATGCATCGGA CACCTTGATA 
AGAAGGGTCC TGGAAGTGTC TCAGGCTCCT GTGATCTTCT CCCACTCAGC TGCCAGAGCT 
GTGTGTGACA ATTTGTTGAA TGTTCCCGAT GATATCCTGC AGCTTCTGAA GAACGGTGGC 
ATCGTGATGG TGACACTGTC CATGGGGGTG CTGCAGTGCA ACCTGCTTGC TAACGTGTCC 
ACTGTGGCAG ATCACTTTGA CCACATCAGG GCAGTCATTG GATCTGAGTT CATCGGGATT 
GGTGGAAATT ATGACGGGAC TGGCCGGTTC CCTCAGGGGC TGGAGGATGT GTCCACATAC 
CCAGTCCTGA TAGAGGAGTT GCTGAGTCGT AGCTGGAGCG AGGAAGAGCT TCAAGGTGTC 
CTTCGTGGAA ACCTGCTGCG GGTCTTCAGA CAAGTGGAAA AGGTGAGAGA GGAGAGCAGG 
GCGCAGAGCC CCGTGGAGGC TGAGTTTCCA TATGGGCAAC TGAGCACATC CTGCCACTCC 
CACCTCGTGC CTCAGAATGG ACACCAGGCT ACTCATCTGG AGGTGACCAA GCAGCCAACC 
AATCGGGTCC CCTGGAGGTC CTCAAATGCC TCCCCATACC TTGTTCCAGG CCTTGTGGCT 
GCTGCCACCA TCCCAACCTT CACCCAGTGG CTCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPEP3 ( NM_022357.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071752.3 Homo sapiens dipeptidase 3 (DPEP3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu31532
Clone ID Related Accession (Same CDS sequence)	NM_022357.3 , NM_022357.4
Accession Version	NM_022357.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	dipeptidase 3 isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK057401.1 and AJ291679.1. On Jun 29, 2008 this sequence version replaced NM_022357.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). CCDS Note: The translation start codon selected for this CCDS is conserved in primates. A possible downstream translation start codon, which is better conserved across species and is consistent with the dipeptidase 2 family member, would reduce the protein length by 25 aa. No experimental evidence exists regarding which start codon is used. ##Evidence-Data-START## Transcript exon combination :: AK057401.1, BC057789.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATCCGGA CCCCATTGTC GGCCTCTGCC CATCGCCTGC TCCTCCCAGG CTCCCGCGGC 
CGACCCCCGC GCAACATGCA GCCCACGGGC CGCGAGGGTT CCCGCGCGCT CAGCCGGCGG 
TATCTGCGGC GTCTGCTGCT CCTGCTACTG CTGCTGCTGC TGCGGCAGCC CGTAACCCGC 
GCGGAGACCA CGCCGGGCGC CCCCAGAGCC CTCTCCACGC TGGGCTCCCC CAGCCTCTTC 
ACCACGCCGG GTGTCCCCAG CGCCCTCACT ACCCCAGGCC TCACTACGCC AGGCACCCCC 
AAAACCCTGG ACCTTCGGGG TCGCGCGCAG GCCCTGATGC GGAGTTTCCC ACTCGTGGAC 
GGCCACAATG ACCTGCCCCA GGTCCTGAGA CAGCGTTACA AGAATGTGCT TCAGGATGTT 
AACCTGCGAA ATTTCAGCCA TGGTCAGACC AGCCTGGACA GGCTTAGAGA CGGCCTCGTG 
GGTGCCCAGT TCTGGTCAGC CTCCGTCTCA TGCCAGTCCC AGGACCAGAC TGCCGTGCGC 
CTCGCCCTGG AGCAGATTGA CCTCATTCAC CGCATGTGTG CCTCCTACTC TGAACTCGAG 
CTTGTGACCT CAGCTGAAGG TCTGAACAGC TCTCAAAAGC TGGCCTGCCT CATTGGCGTG 
GAGGGTGGTC ACTCACTGGA CAGCAGCCTC TCTGTGCTGC GCAGTTTCTA TGTGCTGGGG 
GTGCGCTACC TGACACTTAC CTTCACCTGC AGTACACCAT GGGCAGAGAG TTCCACCAAG 
TTCAGACACC ACATGTACAC CAACGTCAGC GGATTGACAA GCTTTGGTGA GAAAGTAGTA 
GAGGAGTTGA ACCGCCTGGG CATGATGATA GATTTGTCCT ATGCATCGGA CACCTTGATA 
AGAAGGGTCC TGGAAGTGTC TCAGGCTCCT GTGATCTTCT CCCACTCAGC TGCCAGAGCT 
GTGTGTGACA ATTTGTTGAA TGTTCCCGAT GATATCCTGC AGCTTCTGAA GAAGAACGGT 
GGCATCGTGA TGGTGACACT GTCCATGGGG GTGCTGCAGT GCAACCTGCT TGCTAACGTG 
TCCACTGTGG CAGATCACTT TGACCACATC AGGGCAGTCA TTGGATCTGA GTTCATCGGG 
ATTGGTGGAA ATTATGACGG GACTGGCCGG TTCCCTCAGG GGCTGGAGGA TGTGTCCACA 
TACCCAGTCC TGATAGAGGA GTTGCTGAGT CGTAGCTGGA GCGAGGAAGA GCTTCAAGGT 
GTCCTTCGTG GAAACCTGCT GCGGGTCTTC AGACAAGTGG AAAAGGTGAG AGAGGAGAGC 
AGGGCGCAGA GCCCCGTGGA GGCTGAGTTT CCATATGGGC AACTGAGCAC ATCCTGCCAC 
TCCCACCTCG TGCCTCAGAA TGGACACCAG GCTACTCATC TGGAGGTGAC CAAGCAGCCA 
ACCAATCGGG TCCCCTGGAG GTCCTCAAAT GCCTCCCCAT ACCTTGTTCC AGGCCTTGTG 
GCTGCTGCCA CCATCCCAAC CTTCACCCAG TGGCTCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071752.3
CDS	95..1636
Translation	MIRTPLSASAHRLLLPGSRGRPPRNMQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGVPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSPVEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATIPTFTQWLC

Target ORF information:

RefSeq Version	NM_022357.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022357.3

ORF Insert Sequence:

ATGATCCGGA CCCCATTGTC GGCCTCTGCC CATCGCCTGC TCCTCCCAGG CTCCCGCGGC 
CGACCCCCGC GCAACATGCA GCCCACGGGC CGCGAGGGTT CCCGCGCGCT CAGCCGGCGG 
TATCTGCGGC GTCTGCTGCT CCTGCTACTG CTGCTGCTGC TGCGGCAGCC CGTAACCCGC 
GCGGAGACCA CGCCGGGCGC CCCCAGAGCC CTCTCCACGC TGGGCTCCCC CAGCCTCTTC 
ACCACGCCGG GTGTCCCCAG CGCCCTCACT ACCCCAGGCC TCACTACGCC AGGCACCCCC 
AAAACCCTGG ACCTTCGGGG TCGCGCGCAG GCCCTGATGC GGAGTTTCCC ACTCGTGGAC 
GGCCACAATG ACCTGCCCCA GGTCCTGAGA CAGCGTTACA AGAATGTGCT TCAGGATGTT 
AACCTGCGAA ATTTCAGCCA TGGTCAGACC AGCCTGGACA GGCTTAGAGA CGGCCTCGTG 
GGTGCCCAGT TCTGGTCAGC CTCCGTCTCA TGCCAGTCCC AGGACCAGAC TGCCGTGCGC 
CTCGCCCTGG AGCAGATTGA CCTCATTCAC CGCATGTGTG CCTCCTACTC TGAACTCGAG 
CTTGTGACCT CAGCTGAAGG TCTGAACAGC TCTCAAAAGC TGGCCTGCCT CATTGGCGTG 
GAGGGTGGTC ACTCACTGGA CAGCAGCCTC TCTGTGCTGC GCAGTTTCTA TGTGCTGGGG 
GTGCGCTACC TGACACTTAC CTTCACCTGC AGTACACCAT GGGCAGAGAG TTCCACCAAG 
TTCAGACACC ACATGTACAC CAACGTCAGC GGATTGACAA GCTTTGGTGA GAAAGTAGTA 
GAGGAGTTGA ACCGCCTGGG CATGATGATA GATTTGTCCT ATGCATCGGA CACCTTGATA 
AGAAGGGTCC TGGAAGTGTC TCAGGCTCCT GTGATCTTCT CCCACTCAGC TGCCAGAGCT 
GTGTGTGACA ATTTGTTGAA TGTTCCCGAT GATATCCTGC AGCTTCTGAA GAAGAACGGT 
GGCATCGTGA TGGTGACACT GTCCATGGGG GTGCTGCAGT GCAACCTGCT TGCTAACGTG 
TCCACTGTGG CAGATCACTT TGACCACATC AGGGCAGTCA TTGGATCTGA GTTCATCGGG 
ATTGGTGGAA ATTATGACGG GACTGGCCGG TTCCCTCAGG GGCTGGAGGA TGTGTCCACA 
TACCCAGTCC TGATAGAGGA GTTGCTGAGT CGTAGCTGGA GCGAGGAAGA GCTTCAAGGT 
GTCCTTCGTG GAAACCTGCT GCGGGTCTTC AGACAAGTGG AAAAGGTGAG AGAGGAGAGC 
AGGGCGCAGA GCCCCGTGGA GGCTGAGTTT CCATATGGGC AACTGAGCAC ATCCTGCCAC 
TCCCACCTCG TGCCTCAGAA TGGACACCAG GCTACTCATC TGGAGGTGAC CAAGCAGCCA 
ACCAATCGGG TCCCCTGGAG GTCCTCAAAT GCCTCCCCAT ACCTTGTTCC AGGCCTTGTG 
GCTGCTGCCA CCATCCCAAC CTTCACCCAG TGGCTCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPEP3 ( NM_001370198.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001357127.1 Homo sapiens dipeptidase 3 (DPEP3), transcript variant 3, mRNA.

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CloneID	OHu108549
Clone ID Related Accession (Same CDS sequence)	NM_001370198.1
Accession Version	NM_001370198.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1467bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	dipeptidase 3 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK057401.1 and AY358390.1. CCDS Note: The coding region has been updated to start at an alternate start codon that is better supported by conservation data. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved MANE Ensembl match :: ENST00000268793.6/ ENSP00000268793.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGCAGCCCA CGGGCCGCGA GGGTTCCCGC GCGCTCAGCC GGCGGTATCT GCGGCGTCTG 
CTGCTCCTGC TACTGCTGCT GCTGCTGCGG CAGCCCGTAA CCCGCGCGGA GACCACGCCG 
GGCGCCCCCA GAGCCCTCTC CACGCTGGGC TCCCCCAGCC TCTTCACCAC GCCGGGTGTC 
CCCAGCGCCC TCACTACCCC AGGCCTCACT ACGCCAGGCA CCCCCAAAAC CCTGGACCTT 
CGGGGTCGCG CGCAGGCCCT GATGCGGAGT TTCCCACTCG TGGACGGCCA CAATGACCTG 
CCCCAGGTCC TGAGACAGCG TTACAAGAAT GTGCTTCAGG ATGTTAACCT GCGAAATTTC 
AGCCATGGTC AGACCAGCCT GGACAGGCTT AGAGACGGCC TCGTGGGTGC CCAGTTCTGG 
TCAGCCTCCG TCTCATGCCA GTCCCAGGAC CAGACTGCCG TGCGCCTCGC CCTGGAGCAG 
ATTGACCTCA TTCACCGCAT GTGTGCCTCC TACTCTGAAC TCGAGCTTGT GACCTCAGCT 
GAAGGTCTGA ACAGCTCTCA AAAGCTGGCC TGCCTCATTG GCGTGGAGGG TGGTCACTCA 
CTGGACAGCA GCCTCTCTGT GCTGCGCAGT TTCTATGTGC TGGGGGTGCG CTACCTGACA 
CTTACCTTCA CCTGCAGTAC ACCATGGGCA GAGAGTTCCA CCAAGTTCAG ACACCACATG 
TACACCAACG TCAGCGGATT GACAAGCTTT GGTGAGAAAG TAGTAGAGGA GTTGAACCGC 
CTGGGCATGA TGATAGATTT GTCCTATGCA TCGGACACCT TGATAAGAAG GGTCCTGGAA 
GTGTCTCAGG CTCCTGTGAT CTTCTCCCAC TCAGCTGCCA GAGCTGTGTG TGACAATTTG 
TTGAATGTTC CCGATGATAT CCTGCAGCTT CTGAAGAAGA ACGGTGGCAT CGTGATGGTG 
ACACTGTCCA TGGGGGTGCT GCAGTGCAAC CTGCTTGCTA ACGTGTCCAC TGTGGCAGAT 
CACTTTGACC ACATCAGGGC AGTCATTGGA TCTGAGTTCA TCGGGATTGG TGGAAATTAT 
GACGGGACTG GCCGGTTCCC TCAGGGGCTG GAGGATGTGT CCACATACCC AGTCCTGATA 
GAGGAGTTGC TGAGTCGTAG CTGGAGCGAG GAAGAGCTTC AAGGTGTCCT TCGTGGAAAC 
CTGCTGCGGG TCTTCAGACA AGTGGAAAAG GTGAGAGAGG AGAGCAGGGC GCAGAGCCCC 
GTGGAGGCTG AGTTTCCATA TGGGCAACTG AGCACATCCT GCCACTCCCA CCTCGTGCCT 
CAGAATGGAC ACCAGGCTAC TCATCTGGAG GTGACCAAGC AGCCAACCAA TCGGGTCCCC 
TGGAGGTCCT CAAATGCCTC CCCATACCTT GTTCCAGGCC TTGTGGCTGC TGCCACCATC 
CCAACCTTCA CCCAGTGGCT CTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001357127.1
CDS	120..1586
Translation	MQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGVPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSPVEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATIPTFTQWLC

Target ORF information:

RefSeq Version	NM_001370198.1
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001370198.1

ORF Insert Sequence:

ATGCAGCCCA CGGGCCGCGA GGGTTCCCGC GCGCTCAGCC GGCGGTATCT GCGGCGTCTG 
CTGCTCCTGC TACTGCTGCT GCTGCTGCGG CAGCCCGTAA CCCGCGCGGA GACCACGCCG 
GGCGCCCCCA GAGCCCTCTC CACGCTGGGC TCCCCCAGCC TCTTCACCAC GCCGGGTGTC 
CCCAGCGCCC TCACTACCCC AGGCCTCACT ACGCCAGGCA CCCCCAAAAC CCTGGACCTT 
CGGGGTCGCG CGCAGGCCCT GATGCGGAGT TTCCCACTCG TGGACGGCCA CAATGACCTG 
CCCCAGGTCC TGAGACAGCG TTACAAGAAT GTGCTTCAGG ATGTTAACCT GCGAAATTTC 
AGCCATGGTC AGACCAGCCT GGACAGGCTT AGAGACGGCC TCGTGGGTGC CCAGTTCTGG 
TCAGCCTCCG TCTCATGCCA GTCCCAGGAC CAGACTGCCG TGCGCCTCGC CCTGGAGCAG 
ATTGACCTCA TTCACCGCAT GTGTGCCTCC TACTCTGAAC TCGAGCTTGT GACCTCAGCT 
GAAGGTCTGA ACAGCTCTCA AAAGCTGGCC TGCCTCATTG GCGTGGAGGG TGGTCACTCA 
CTGGACAGCA GCCTCTCTGT GCTGCGCAGT TTCTATGTGC TGGGGGTGCG CTACCTGACA 
CTTACCTTCA CCTGCAGTAC ACCATGGGCA GAGAGTTCCA CCAAGTTCAG ACACCACATG 
TACACCAACG TCAGCGGATT GACAAGCTTT GGTGAGAAAG TAGTAGAGGA GTTGAACCGC 
CTGGGCATGA TGATAGATTT GTCCTATGCA TCGGACACCT TGATAAGAAG GGTCCTGGAA 
GTGTCTCAGG CTCCTGTGAT CTTCTCCCAC TCAGCTGCCA GAGCTGTGTG TGACAATTTG 
TTGAATGTTC CCGATGATAT CCTGCAGCTT CTGAAGAAGA ACGGTGGCAT CGTGATGGTG 
ACACTGTCCA TGGGGGTGCT GCAGTGCAAC CTGCTTGCTA ACGTGTCCAC TGTGGCAGAT 
CACTTTGACC ACATCAGGGC AGTCATTGGA TCTGAGTTCA TCGGGATTGG TGGAAATTAT 
GACGGGACTG GCCGGTTCCC TCAGGGGCTG GAGGATGTGT CCACATACCC AGTCCTGATA 
GAGGAGTTGC TGAGTCGTAG CTGGAGCGAG GAAGAGCTTC AAGGTGTCCT TCGTGGAAAC 
CTGCTGCGGG TCTTCAGACA AGTGGAAAAG GTGAGAGAGG AGAGCAGGGC GCAGAGCCCC 
GTGGAGGCTG AGTTTCCATA TGGGCAACTG AGCACATCCT GCCACTCCCA CCTCGTGCCT 
CAGAATGGAC ACCAGGCTAC TCATCTGGAG GTGACCAAGC AGCCAACCAA TCGGGTCCCC 
TGGAGGTCCT CAAATGCCTC CCCATACCTT GTTCCAGGCC TTGTGGCTGC TGCCACCATC 
CCAACCTTCA CCCAGTGGCT CTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DPEP3 ( NM_001129758.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001123230.2 Homo sapiens dipeptidase 3 (DPEP3), transcript variant 2, mRNA.

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CloneID	OHu108553
Clone ID Related Accession (Same CDS sequence)	NM_001129758.2
Accession Version	NM_001129758.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-24
Organism	Homo sapiens(human)
Product	dipeptidase 3 isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HM005556.1. On May 2, 2019 this sequence version replaced NM_001129758.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter, compared to isoform a. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCAGCCCA CGGGCCGCGA GGGTTCCCGC GCGCTCAGCC GGCGGTATCT GCGGCGTCTG 
CTGCTCCTGC TACTGCTGCT GCTGCTGCGG CAGCCCGTAA CCCGCGCGGA GACCACGCCG 
GGCGCCCCCA GAGCCCTCTC CACGCTGGGC TCCCCCAGCC TCTTCACCAC GCCGGGTGTC 
CCCAGCGCCC TCACTACCCC AGGCCTCACT ACGCCAGGCA CCCCCAAAAC CCTGGACCTT 
CGGGGTCGCG CGCAGGCCCT GATGCGGAGT TTCCCACTCG TGGACGGCCA CAATGACCTG 
CCCCAGGTCC TGAGACAGCG TTACAAGAAT GTGCTTCAGG ATGTTAACCT GCGAAATTTC 
AGCCATGGTC AGACCAGCCT GGACAGGCTT AGAGACGGCC TCGTGGGTGC CCAGTTCTGG 
TCAGCCTCCG TCTCATGCCA GTCCCAGGAC CAGACTGCCG TGCGCCTCGC CCTGGAGCAG 
ATTGACCTCA TTCACCGCAT GTGTGCCTCC TACTCTGAAC TCGAGCTTGT GACCTCAGCT 
GAAGGTCTGA ACAGCTCTCA AAAGCTGGCC TGCCTCATTG GCGTGGAGGG TGGTCACTCA 
CTGGACAGCA GCCTCTCTGT GCTGCGCAGT TTCTATGTGC TGGGGGTGCG CTACCTGACA 
CTTACCTTCA CCTGCAGTAC ACCATGGGCA GAGAGTTCCA CCAAGTTCAG ACACCACATG 
TACACCAACG TCAGCGGATT GACAAGCTTT GGTGAGAAAG TAGTAGAGGA GTTGAACCGC 
CTGGGCATGA TGATAGATTT GTCCTATGCA TCGGACACCT TGATAAGAAG GGTCCTGGAA 
GTGTCTCAGG CTCCTGTGAT CTTCTCCCAC TCAGCTGCCA GAGCTGTGTG TGACAATTTG 
TTGAATGTTC CCGATGATAT CCTGCAGCTT CTGAAGAACG GTGGCATCGT GATGGTGACA 
CTGTCCATGG GGGTGCTGCA GTGCAACCTG CTTGCTAACG TGTCCACTGT GGCAGATCAC 
TTTGACCACA TCAGGGCAGT CATTGGATCT GAGTTCATCG GGATTGGTGG AAATTATGAC 
GGGACTGGCC GGTTCCCTCA GGGGCTGGAG GATGTGTCCA CATACCCAGT CCTGATAGAG 
GAGTTGCTGA GTCGTAGCTG GAGCGAGGAA GAGCTTCAAG GTGTCCTTCG TGGAAACCTG 
CTGCGGGTCT TCAGACAAGT GGAAAAGGTG AGAGAGGAGA GCAGGGCGCA GAGCCCCGTG 
GAGGCTGAGT TTCCATATGG GCAACTGAGC ACATCCTGCC ACTCCCACCT CGTGCCTCAG 
AATGGACACC AGGCTACTCA TCTGGAGGTG ACCAAGCAGC CAACCAATCG GGTCCCCTGG 
AGGTCCTCAA ATGCCTCCCC ATACCTTGTT CCAGGCCTTG TGGCTGCTGC CACCATCCCA 
ACCTTCACCC AGTGGCTCTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123230.2
CDS	120..1583
Translation	MQPTGREGSRALSRRYLRRLLLLLLLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPGVPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRNFSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYSELELVTSAEGLNSSQKLACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLTFTCSTPWAESSTKFRHHMYTNVSGLTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCDNLLNVPDDILQLLKNGGIVMVTLSMGVLQCNLLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRSWSEEELQGVLRGNLLRVFRQVEKVREESRAQSPVEAEFPYGQLSTSCHSHLVPQNGHQATHLEVTKQPTNRVPWRSSNASPYLVPGLVAAATIPTFTQWLC

Target ORF information:

RefSeq Version	NM_001129758.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dipeptidase 3 (DPEP3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129758.2

ORF Insert Sequence:

ATGCAGCCCA CGGGCCGCGA GGGTTCCCGC GCGCTCAGCC GGCGGTATCT GCGGCGTCTG 
CTGCTCCTGC TACTGCTGCT GCTGCTGCGG CAGCCCGTAA CCCGCGCGGA GACCACGCCG 
GGCGCCCCCA GAGCCCTCTC CACGCTGGGC TCCCCCAGCC TCTTCACCAC GCCGGGTGTC 
CCCAGCGCCC TCACTACCCC AGGCCTCACT ACGCCAGGCA CCCCCAAAAC CCTGGACCTT 
CGGGGTCGCG CGCAGGCCCT GATGCGGAGT TTCCCACTCG TGGACGGCCA CAATGACCTG 
CCCCAGGTCC TGAGACAGCG TTACAAGAAT GTGCTTCAGG ATGTTAACCT GCGAAATTTC 
AGCCATGGTC AGACCAGCCT GGACAGGCTT AGAGACGGCC TCGTGGGTGC CCAGTTCTGG 
TCAGCCTCCG TCTCATGCCA GTCCCAGGAC CAGACTGCCG TGCGCCTCGC CCTGGAGCAG 
ATTGACCTCA TTCACCGCAT GTGTGCCTCC TACTCTGAAC TCGAGCTTGT GACCTCAGCT 
GAAGGTCTGA ACAGCTCTCA AAAGCTGGCC TGCCTCATTG GCGTGGAGGG TGGTCACTCA 
CTGGACAGCA GCCTCTCTGT GCTGCGCAGT TTCTATGTGC TGGGGGTGCG CTACCTGACA 
CTTACCTTCA CCTGCAGTAC ACCATGGGCA GAGAGTTCCA CCAAGTTCAG ACACCACATG 
TACACCAACG TCAGCGGATT GACAAGCTTT GGTGAGAAAG TAGTAGAGGA GTTGAACCGC 
CTGGGCATGA TGATAGATTT GTCCTATGCA TCGGACACCT TGATAAGAAG GGTCCTGGAA 
GTGTCTCAGG CTCCTGTGAT CTTCTCCCAC TCAGCTGCCA GAGCTGTGTG TGACAATTTG 
TTGAATGTTC CCGATGATAT CCTGCAGCTT CTGAAGAACG GTGGCATCGT GATGGTGACA 
CTGTCCATGG GGGTGCTGCA GTGCAACCTG CTTGCTAACG TGTCCACTGT GGCAGATCAC 
TTTGACCACA TCAGGGCAGT CATTGGATCT GAGTTCATCG GGATTGGTGG AAATTATGAC 
GGGACTGGCC GGTTCCCTCA GGGGCTGGAG GATGTGTCCA CATACCCAGT CCTGATAGAG 
GAGTTGCTGA GTCGTAGCTG GAGCGAGGAA GAGCTTCAAG GTGTCCTTCG TGGAAACCTG 
CTGCGGGTCT TCAGACAAGT GGAAAAGGTG AGAGAGGAGA GCAGGGCGCA GAGCCCCGTG 
GAGGCTGAGT TTCCATATGG GCAACTGAGC ACATCCTGCC ACTCCCACCT CGTGCCTCAG 
AATGGACACC AGGCTACTCA TCTGGAGGTG ACCAAGCAGC CAACCAATCG GGTCCCCTGG 
AGGTCCTCAA ATGCCTCCCC ATACCTTGTT CCAGGCCTTG TGGCTGCTGC CACCATCCCA 
ACCTTCACCC AGTGGCTCTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
Nature genetics41(1)35-46(2009 Jan)
Sabatti C,Service SK,Hartikainen AL,Pouta A,Ripatti S,Brodsky J,Jones CG,Zaitlen NA,Varilo T,Kaakinen M,Sovio U,Ruokonen A,Laitinen J,Jakkula E,Coin L,Hoggart C,Collins A,Turunen H,Gabriel S,Elliot P,McCarthy MI,Daly MJ,J?rvelin MR,Freimer NB,Peltonen L

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

Identification of two additional members of the membrane-bound dipeptidase family.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology17(10)1313-5(2003 Jul)
Habib GM,Shi ZZ,Cuevas AA,Lieberman MW

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DPEP3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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