MAP2K4 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_003010.3	NP_003001.1	dual specificity mitogen-activated protein kinase kinase 4 isoform 1
NM_001281435.1	NP_001268364.1	dual specificity mitogen-activated protein kinase kinase 4 isoform 2
NM_001281435.2	NP_001268364.1	dual specificity mitogen-activated protein kinase kinase 4 isoform 2
NM_003010.4	NP_003001.1	dual specificity mitogen-activated protein kinase kinase 4 isoform 1
XM_005256753.3	XP_005256810.1	dual specificity mitogen-activated protein kinase kinase 4 isoform X2
XM_005256755.2	XP_005256812.1	dual specificity mitogen-activated protein kinase kinase 4 isoform X3
XM_011523976.2	XP_011522278.1	dual specificity mitogen-activated protein kinase kinase 4 isoform X1
XM_011523977.2	XP_011522279.1	dual specificity mitogen-activated protein kinase kinase 4 isoform X3
XM_005256753.2	XP_005256810.1	dual specificity mitogen-activated protein kinase kinase 4 isoform X2

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14638	NM_003010.4 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu20838	NM_001281435.2 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu49912	XM_005256753.3 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu49913	XM_011523977.2 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu49913	XM_005256755.2 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu60445	XM_011523976.2 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu20838	NM_001281435.1	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu14638	NM_003010.3	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu49912	XM_005256753.2	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

MAP2K4 ( NM_003010.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003001.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14638
Clone ID Related Accession (Same CDS sequence)	NM_003010.3 , NM_003010.4
Accession Version	NM_003010.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-19
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036032.1, L36870.1, BQ028457.1 and AU150695.1. On Jul 25, 2013 this sequence version replaced NM_003010.2. Transcript Variant: This variant (1) encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036032.1, BC060764.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGTAAA 
CGCAAAGCAC TGAAGTTGAA TTTTGCAAAT CCACCTTTCA AATCTACAGC AAGGTTTACT 
CTGAATCCCA ATCCTACAGG AGTTCAAAAC CCACACATAG AGAGACTGAG AACACACAGC 
ATTGAGTCAT CAGGAAAACT GAAGATCTCC CCTGAACAAC ACTGGGATTT CACTGCAGAG 
GACTTGAAAG ACCTTGGAGA AATTGGACGA GGAGCTTATG GTTCTGTCAA CAAAATGGTC 
CACAAACCAA GTGGGCAAAT AATGGCAGTT AAAAGAATTC GGTCAACAGT GGATGAAAAA 
GAACAAAAAC AACTTCTTAT GGATTTGGAT GTAGTAATGC GGAGTAGTGA TTGCCCATAC 
ATTGTTCAGT TTTATGGTGC ACTCTTCAGA GAGGGTGACT GTTGGATCTG TATGGAACTC 
ATGTCTACCT CGTTTGATAA GTTTTACAAA TATGTATATA GTGTATTAGA TGATGTTATT 
CCAGAAGAAA TTTTAGGCAA AATCACTTTA GCAACTGTGA AAGCACTAAA CCACTTAAAA 
GAAAACTTGA AAATTATTCA CAGAGATATC AAACCTTCCA ATATTCTTCT GGACAGAAGT 
GGAAATATTA AGCTCTGTGA CTTCGGCATC AGTGGACAGC TTGTGGACTC TATTGCCAAG 
ACAAGAGATG CTGGCTGTAG GCCATACATG GCACCTGAAA GAATAGACCC AAGCGCATCA 
CGACAAGGAT ATGATGTCCG CTCTGATGTC TGGAGTTTGG GGATCACATT GTATGAGTTG 
GCCACAGGCC GATTTCCTTA TCCAAAGTGG AATAGTGTAT TTGATCAACT AACACAAGTC 
GTGAAAGGAG ATCCTCCGCA GCTGAGTAAT TCTGAGGAAA GGGAATTCTC CCCGAGTTTC 
ATCAACTTTG TCAACTTGTG CCTTACGAAG GATGAATCCA AAAGGCCAAA GTATAAAGAG 
CTTCTGAAAC ATCCCTTTAT TTTGATGTAT GAAGAACGTG CCGTTGAGGT CGCATGCTAT 
GTTTGTAAAA TCCTGGATCA AATGCCAGCT ACTCCCAGCT CTCCCATGTA TGTCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003001.1
CDS	70..1269
Translation	MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	NM_003010.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003010.3

ORF Insert Sequence:

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGTAAA 
CGCAAAGCAC TGAAGTTGAA TTTTGCAAAT CCACCTTTCA AATCTACAGC AAGGTTTACT 
CTGAATCCCA ATCCTACAGG AGTTCAAAAC CCACACATAG AGAGACTGAG AACACACAGC 
ATTGAGTCAT CAGGAAAACT GAAGATCTCC CCTGAACAAC ACTGGGATTT CACTGCAGAG 
GACTTGAAAG ACCTTGGAGA AATTGGACGA GGAGCTTATG GTTCTGTCAA CAAAATGGTC 
CACAAACCAA GTGGGCAAAT AATGGCAGTT AAAAGAATTC GGTCAACAGT GGATGAAAAA 
GAACAAAAAC AACTTCTTAT GGATTTGGAT GTAGTAATGC GGAGTAGTGA TTGCCCATAC 
ATTGTTCAGT TTTATGGTGC ACTCTTCAGA GAGGGTGACT GTTGGATCTG TATGGAACTC 
ATGTCTACCT CGTTTGATAA GTTTTACAAA TATGTATATA GTGTATTAGA TGATGTTATT 
CCAGAAGAAA TTTTAGGCAA AATCACTTTA GCAACTGTGA AAGCACTAAA CCACTTAAAA 
GAAAACTTGA AAATTATTCA CAGAGATATC AAACCTTCCA ATATTCTTCT GGACAGAAGT 
GGAAATATTA AGCTCTGTGA CTTCGGCATC AGTGGACAGC TTGTGGACTC TATTGCCAAG 
ACAAGAGATG CTGGCTGTAG GCCATACATG GCACCTGAAA GAATAGACCC AAGCGCATCA 
CGACAAGGAT ATGATGTCCG CTCTGATGTC TGGAGTTTGG GGATCACATT GTATGAGTTG 
GCCACAGGCC GATTTCCTTA TCCAAAGTGG AATAGTGTAT TTGATCAACT AACACAAGTC 
GTGAAAGGAG ATCCTCCGCA GCTGAGTAAT TCTGAGGAAA GGGAATTCTC CCCGAGTTTC 
ATCAACTTTG TCAACTTGTG CCTTACGAAG GATGAATCCA AAAGGCCAAA GTATAAAGAG 
CTTCTGAAAC ATCCCTTTAT TTTGATGTAT GAAGAACGTG CCGTTGAGGT CGCATGCTAT 
GTTTGTAAAA TCCTGGATCA AATGCCAGCT ACTCCCAGCT CTCCCATGTA TGTCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( NM_003010.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003001.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14638
Clone ID Related Accession (Same CDS sequence)	NM_003010.3 , NM_003010.4
Accession Version	NM_003010.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1200bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC036032.1, L36870.1, BQ028457.1 and AU150695.1. On Nov 23, 2018 this sequence version replaced NM_003010.3. Transcript Variant: This variant (1) encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.39130.1, BC060764.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000353533.10/ ENSP00000262445.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGTAAA 
CGCAAAGCAC TGAAGTTGAA TTTTGCAAAT CCACCTTTCA AATCTACAGC AAGGTTTACT 
CTGAATCCCA ATCCTACAGG AGTTCAAAAC CCACACATAG AGAGACTGAG AACACACAGC 
ATTGAGTCAT CAGGAAAACT GAAGATCTCC CCTGAACAAC ACTGGGATTT CACTGCAGAG 
GACTTGAAAG ACCTTGGAGA AATTGGACGA GGAGCTTATG GTTCTGTCAA CAAAATGGTC 
CACAAACCAA GTGGGCAAAT AATGGCAGTT AAAAGAATTC GGTCAACAGT GGATGAAAAA 
GAACAAAAAC AACTTCTTAT GGATTTGGAT GTAGTAATGC GGAGTAGTGA TTGCCCATAC 
ATTGTTCAGT TTTATGGTGC ACTCTTCAGA GAGGGTGACT GTTGGATCTG TATGGAACTC 
ATGTCTACCT CGTTTGATAA GTTTTACAAA TATGTATATA GTGTATTAGA TGATGTTATT 
CCAGAAGAAA TTTTAGGCAA AATCACTTTA GCAACTGTGA AAGCACTAAA CCACTTAAAA 
GAAAACTTGA AAATTATTCA CAGAGATATC AAACCTTCCA ATATTCTTCT GGACAGAAGT 
GGAAATATTA AGCTCTGTGA CTTCGGCATC AGTGGACAGC TTGTGGACTC TATTGCCAAG 
ACAAGAGATG CTGGCTGTAG GCCATACATG GCACCTGAAA GAATAGACCC AAGCGCATCA 
CGACAAGGAT ATGATGTCCG CTCTGATGTC TGGAGTTTGG GGATCACATT GTATGAGTTG 
GCCACAGGCC GATTTCCTTA TCCAAAGTGG AATAGTGTAT TTGATCAACT AACACAAGTC 
GTGAAAGGAG ATCCTCCGCA GCTGAGTAAT TCTGAGGAAA GGGAATTCTC CCCGAGTTTC 
ATCAACTTTG TCAACTTGTG CCTTACGAAG GATGAATCCA AAAGGCCAAA GTATAAAGAG 
CTTCTGAAAC ATCCCTTTAT TTTGATGTAT GAAGAACGTG CCGTTGAGGT CGCATGCTAT 
GTTTGTAAAA TCCTGGATCA AATGCCAGCT ACTCCCAGCT CTCCCATGTA TGTCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003001.1
CDS	11..1210
Translation	MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	NM_003010.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003010.4

ORF Insert Sequence:

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGTAAA 
CGCAAAGCAC TGAAGTTGAA TTTTGCAAAT CCACCTTTCA AATCTACAGC AAGGTTTACT 
CTGAATCCCA ATCCTACAGG AGTTCAAAAC CCACACATAG AGAGACTGAG AACACACAGC 
ATTGAGTCAT CAGGAAAACT GAAGATCTCC CCTGAACAAC ACTGGGATTT CACTGCAGAG 
GACTTGAAAG ACCTTGGAGA AATTGGACGA GGAGCTTATG GTTCTGTCAA CAAAATGGTC 
CACAAACCAA GTGGGCAAAT AATGGCAGTT AAAAGAATTC GGTCAACAGT GGATGAAAAA 
GAACAAAAAC AACTTCTTAT GGATTTGGAT GTAGTAATGC GGAGTAGTGA TTGCCCATAC 
ATTGTTCAGT TTTATGGTGC ACTCTTCAGA GAGGGTGACT GTTGGATCTG TATGGAACTC 
ATGTCTACCT CGTTTGATAA GTTTTACAAA TATGTATATA GTGTATTAGA TGATGTTATT 
CCAGAAGAAA TTTTAGGCAA AATCACTTTA GCAACTGTGA AAGCACTAAA CCACTTAAAA 
GAAAACTTGA AAATTATTCA CAGAGATATC AAACCTTCCA ATATTCTTCT GGACAGAAGT 
GGAAATATTA AGCTCTGTGA CTTCGGCATC AGTGGACAGC TTGTGGACTC TATTGCCAAG 
ACAAGAGATG CTGGCTGTAG GCCATACATG GCACCTGAAA GAATAGACCC AAGCGCATCA 
CGACAAGGAT ATGATGTCCG CTCTGATGTC TGGAGTTTGG GGATCACATT GTATGAGTTG 
GCCACAGGCC GATTTCCTTA TCCAAAGTGG AATAGTGTAT TTGATCAACT AACACAAGTC 
GTGAAAGGAG ATCCTCCGCA GCTGAGTAAT TCTGAGGAAA GGGAATTCTC CCCGAGTTTC 
ATCAACTTTG TCAACTTGTG CCTTACGAAG GATGAATCCA AAAGGCCAAA GTATAAAGAG 
CTTCTGAAAC ATCCCTTTAT TTTGATGTAT GAAGAACGTG CCGTTGAGGT CGCATGCTAT 
GTTTGTAAAA TCCTGGATCA AATGCCAGCT ACTCCCAGCT CTCCCATGTA TGTCGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( NM_001281435.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001268364.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20838
Clone ID Related Accession (Same CDS sequence)	NM_001281435.1 , NM_001281435.2
Accession Version	NM_001281435.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005410.3, AK131544.1, AC005244.1 and AU150695.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) contains an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is longer compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK131544.1, SRR1803611.144078.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGCTTT 
CAGATAAACT TCTGTGAAAA GGCACAAAGT AAACGCAAAG CACTGAAGTT GAATTTTGCA 
AATCCACCTT TCAAATCTAC AGCAAGGTTT ACTCTGAATC CCAATCCTAC AGGAGTTCAA 
AACCCACACA TAGAGAGACT GAGAACACAC AGCATTGAGT CATCAGGAAA ACTGAAGATC 
TCCCCTGAAC AACACTGGGA TTTCACTGCA GAGGACTTGA AAGACCTTGG AGAAATTGGA 
CGAGGAGCTT ATGGTTCTGT CAACAAAATG GTCCACAAAC CAAGTGGGCA AATAATGGCA 
GTTAAAAGAA TTCGGTCAAC AGTGGATGAA AAAGAACAAA AACAACTTCT TATGGATTTG 
GATGTAGTAA TGCGGAGTAG TGATTGCCCA TACATTGTTC AGTTTTATGG TGCACTCTTC 
AGAGAGGGTG ACTGTTGGAT CTGTATGGAA CTCATGTCTA CCTCGTTTGA TAAGTTTTAC 
AAATATGTAT ATAGTGTATT AGATGATGTT ATTCCAGAAG AAATTTTAGG CAAAATCACT 
TTAGCAACTG TGAAAGCACT AAACCACTTA AAAGAAAACT TGAAAATTAT TCACAGAGAT 
ATCAAACCTT CCAATATTCT TCTGGACAGA AGTGGAAATA TTAAGCTCTG TGACTTCGGC 
ATCAGTGGAC AGCTTGTGGA CTCTATTGCC AAGACAAGAG ATGCTGGCTG TAGGCCATAC 
ATGGCACCTG AAAGAATAGA CCCAAGCGCA TCACGACAAG GATATGATGT CCGCTCTGAT 
GTCTGGAGTT TGGGGATCAC ATTGTATGAG TTGGCCACAG GCCGATTTCC TTATCCAAAG 
TGGAATAGTG TATTTGATCA ACTAACACAA GTCGTGAAAG GAGATCCTCC GCAGCTGAGT 
AATTCTGAGG AAAGGGAATT CTCCCCGAGT TTCATCAACT TTGTCAACTT GTGCCTTACG 
AAGGATGAAT CCAAAAGGCC AAAGTATAAA GAGCTTCTGA AACATCCCTT TATTTTGATG 
TATGAAGAAC GTGCCGTTGA GGTCGCATGC TATGTTTGTA AAATCCTGGA TCAAATGCCA 
GCTACTCCCA GCTCTCCCAT GTATGTCGAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001268364.1
CDS	70..1302
Translation	MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	NM_001281435.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001281435.1

ORF Insert Sequence:

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGCTTT 
CAGATAAACT TCTGTGAAAA GGCACAAAGT AAACGCAAAG CACTGAAGTT GAATTTTGCA 
AATCCACCTT TCAAATCTAC AGCAAGGTTT ACTCTGAATC CCAATCCTAC AGGAGTTCAA 
AACCCACACA TAGAGAGACT GAGAACACAC AGCATTGAGT CATCAGGAAA ACTGAAGATC 
TCCCCTGAAC AACACTGGGA TTTCACTGCA GAGGACTTGA AAGACCTTGG AGAAATTGGA 
CGAGGAGCTT ATGGTTCTGT CAACAAAATG GTCCACAAAC CAAGTGGGCA AATAATGGCA 
GTTAAAAGAA TTCGGTCAAC AGTGGATGAA AAAGAACAAA AACAACTTCT TATGGATTTG 
GATGTAGTAA TGCGGAGTAG TGATTGCCCA TACATTGTTC AGTTTTATGG TGCACTCTTC 
AGAGAGGGTG ACTGTTGGAT CTGTATGGAA CTCATGTCTA CCTCGTTTGA TAAGTTTTAC 
AAATATGTAT ATAGTGTATT AGATGATGTT ATTCCAGAAG AAATTTTAGG CAAAATCACT 
TTAGCAACTG TGAAAGCACT AAACCACTTA AAAGAAAACT TGAAAATTAT TCACAGAGAT 
ATCAAACCTT CCAATATTCT TCTGGACAGA AGTGGAAATA TTAAGCTCTG TGACTTCGGC 
ATCAGTGGAC AGCTTGTGGA CTCTATTGCC AAGACAAGAG ATGCTGGCTG TAGGCCATAC 
ATGGCACCTG AAAGAATAGA CCCAAGCGCA TCACGACAAG GATATGATGT CCGCTCTGAT 
GTCTGGAGTT TGGGGATCAC ATTGTATGAG TTGGCCACAG GCCGATTTCC TTATCCAAAG 
TGGAATAGTG TATTTGATCA ACTAACACAA GTCGTGAAAG GAGATCCTCC GCAGCTGAGT 
AATTCTGAGG AAAGGGAATT CTCCCCGAGT TTCATCAACT TTGTCAACTT GTGCCTTACG 
AAGGATGAAT CCAAAAGGCC AAAGTATAAA GAGCTTCTGA AACATCCCTT TATTTTGATG 
TATGAAGAAC GTGCCGTTGA GGTCGCATGC TATGTTTGTA AAATCCTGGA TCAAATGCCA 
GCTACTCCCA GCTCTCCCAT GTATGTCGAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( NM_001281435.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001268364.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20838
Clone ID Related Accession (Same CDS sequence)	NM_001281435.1 , NM_001281435.2
Accession Version	NM_001281435.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-25
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005410.3, AK131544.1 and AC005244.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_001281435.1. Transcript Variant: This variant (2) contains an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is longer compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.184439.1, SRR1803611.144078.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGCTTT 
CAGATAAACT TCTGTGAAAA GGCACAAAGT AAACGCAAAG CACTGAAGTT GAATTTTGCA 
AATCCACCTT TCAAATCTAC AGCAAGGTTT ACTCTGAATC CCAATCCTAC AGGAGTTCAA 
AACCCACACA TAGAGAGACT GAGAACACAC AGCATTGAGT CATCAGGAAA ACTGAAGATC 
TCCCCTGAAC AACACTGGGA TTTCACTGCA GAGGACTTGA AAGACCTTGG AGAAATTGGA 
CGAGGAGCTT ATGGTTCTGT CAACAAAATG GTCCACAAAC CAAGTGGGCA AATAATGGCA 
GTTAAAAGAA TTCGGTCAAC AGTGGATGAA AAAGAACAAA AACAACTTCT TATGGATTTG 
GATGTAGTAA TGCGGAGTAG TGATTGCCCA TACATTGTTC AGTTTTATGG TGCACTCTTC 
AGAGAGGGTG ACTGTTGGAT CTGTATGGAA CTCATGTCTA CCTCGTTTGA TAAGTTTTAC 
AAATATGTAT ATAGTGTATT AGATGATGTT ATTCCAGAAG AAATTTTAGG CAAAATCACT 
TTAGCAACTG TGAAAGCACT AAACCACTTA AAAGAAAACT TGAAAATTAT TCACAGAGAT 
ATCAAACCTT CCAATATTCT TCTGGACAGA AGTGGAAATA TTAAGCTCTG TGACTTCGGC 
ATCAGTGGAC AGCTTGTGGA CTCTATTGCC AAGACAAGAG ATGCTGGCTG TAGGCCATAC 
ATGGCACCTG AAAGAATAGA CCCAAGCGCA TCACGACAAG GATATGATGT CCGCTCTGAT 
GTCTGGAGTT TGGGGATCAC ATTGTATGAG TTGGCCACAG GCCGATTTCC TTATCCAAAG 
TGGAATAGTG TATTTGATCA ACTAACACAA GTCGTGAAAG GAGATCCTCC GCAGCTGAGT 
AATTCTGAGG AAAGGGAATT CTCCCCGAGT TTCATCAACT TTGTCAACTT GTGCCTTACG 
AAGGATGAAT CCAAAAGGCC AAAGTATAAA GAGCTTCTGA AACATCCCTT TATTTTGATG 
TATGAAGAAC GTGCCGTTGA GGTCGCATGC TATGTTTGTA AAATCCTGGA TCAAATGCCA 
GCTACTCCCA GCTCTCCCAT GTATGTCGAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001268364.1
CDS	11..1243
Translation	MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	NM_001281435.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001281435.2

ORF Insert Sequence:

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGCTTT 
CAGATAAACT TCTGTGAAAA GGCACAAAGT AAACGCAAAG CACTGAAGTT GAATTTTGCA 
AATCCACCTT TCAAATCTAC AGCAAGGTTT ACTCTGAATC CCAATCCTAC AGGAGTTCAA 
AACCCACACA TAGAGAGACT GAGAACACAC AGCATTGAGT CATCAGGAAA ACTGAAGATC 
TCCCCTGAAC AACACTGGGA TTTCACTGCA GAGGACTTGA AAGACCTTGG AGAAATTGGA 
CGAGGAGCTT ATGGTTCTGT CAACAAAATG GTCCACAAAC CAAGTGGGCA AATAATGGCA 
GTTAAAAGAA TTCGGTCAAC AGTGGATGAA AAAGAACAAA AACAACTTCT TATGGATTTG 
GATGTAGTAA TGCGGAGTAG TGATTGCCCA TACATTGTTC AGTTTTATGG TGCACTCTTC 
AGAGAGGGTG ACTGTTGGAT CTGTATGGAA CTCATGTCTA CCTCGTTTGA TAAGTTTTAC 
AAATATGTAT ATAGTGTATT AGATGATGTT ATTCCAGAAG AAATTTTAGG CAAAATCACT 
TTAGCAACTG TGAAAGCACT AAACCACTTA AAAGAAAACT TGAAAATTAT TCACAGAGAT 
ATCAAACCTT CCAATATTCT TCTGGACAGA AGTGGAAATA TTAAGCTCTG TGACTTCGGC 
ATCAGTGGAC AGCTTGTGGA CTCTATTGCC AAGACAAGAG ATGCTGGCTG TAGGCCATAC 
ATGGCACCTG AAAGAATAGA CCCAAGCGCA TCACGACAAG GATATGATGT CCGCTCTGAT 
GTCTGGAGTT TGGGGATCAC ATTGTATGAG TTGGCCACAG GCCGATTTCC TTATCCAAAG 
TGGAATAGTG TATTTGATCA ACTAACACAA GTCGTGAAAG GAGATCCTCC GCAGCTGAGT 
AATTCTGAGG AAAGGGAATT CTCCCCGAGT TTCATCAACT TTGTCAACTT GTGCCTTACG 
AAGGATGAAT CCAAAAGGCC AAAGTATAAA GAGCTTCTGA AACATCCCTT TATTTTGATG 
TATGAAGAAC GTGCCGTTGA GGTCGCATGC TATGTTTGTA AAATCCTGGA TCAAATGCCA 
GCTACTCCCA GCTCTCCCAT GTATGTCGAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( XM_005256753.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256810.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu49912
Clone ID Related Accession (Same CDS sequence)	XM_005256753.3 , XM_005256753.2
Accession Version	XM_005256753.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005256753.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCACA AACCAAGTGG GCAAATAATG GCAGTTAAAA GAATTCGGTC AACAGTGGAT 
GAAAAAGAAC AAAAACAACT TCTTATGGAT TTGGATGTAG TAATGCGGAG TAGTGATTGC 
CCATACATTG TTCAGTTTTA TGGTGCACTC TTCAGAGAGG GTGACTGTTG GATCTGTATG 
GAACTCATGT CTACCTCGTT TGATAAGTTT TACAAATATG TATATAGTGT ATTAGATGAT 
GTTATTCCAG AAGAAATTTT AGGCAAAATC ACTTTAGCAA CTGTGAAAGC ACTAAACCAC 
TTAAAAGAAA ACTTGAAAAT TATTCACAGA GATATCAAAC CTTCCAATAT TCTTCTGGAC 
AGAAGTGGAA ATATTAAGCT CTGTGACTTC GGCATCAGTG GACAGCTTGT GGACTCTATT 
GCCAAGACAA GAGATGCTGG CTGTAGGCCA TACATGGCAC CTGAAAGAAT AGACCCAAGC 
GCATCACGAC AAGGATATGA TGTCCGCTCT GATGTCTGGA GTTTGGGGAT CACATTGTAT 
GAGTTGGCCA CAGGCCGATT TCCTTATCCA AAGTGGAATA GTGTATTTGA TCAACTAACA 
CAAGTCGTGA AAGGAGATCC TCCGCAGCTG AGTAATTCTG AGGAAAGGGA ATTCTCCCCG 
AGTTTCATCA ACTTTGTCAA CTTGTGCCTT ACGAAGGATG AATCCAAAAG GCCAAAGTAT 
AAAGAGCTTC TGAAACATCC CTTTATTTTG ATGTATGAAG AACGTGCCGT TGAGGTCGCA 
TGCTATGTTT GTAAAATCCT GGATCAAATG CCAGCTACTC CCAGCTCTCC CATGTATGTC 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256810.1
CDS	235..1080
Translation	MVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	XM_005256753.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256753.3

ORF Insert Sequence:

ATGGTCCACA AACCAAGTGG GCAAATAATG GCAGTTAAAA GAATTCGGTC AACAGTGGAT 
GAAAAAGAAC AAAAACAACT TCTTATGGAT TTGGATGTAG TAATGCGGAG TAGTGATTGC 
CCATACATTG TTCAGTTTTA TGGTGCACTC TTCAGAGAGG GTGACTGTTG GATCTGTATG 
GAACTCATGT CTACCTCGTT TGATAAGTTT TACAAATATG TATATAGTGT ATTAGATGAT 
GTTATTCCAG AAGAAATTTT AGGCAAAATC ACTTTAGCAA CTGTGAAAGC ACTAAACCAC 
TTAAAAGAAA ACTTGAAAAT TATTCACAGA GATATCAAAC CTTCCAATAT TCTTCTGGAC 
AGAAGTGGAA ATATTAAGCT CTGTGACTTC GGCATCAGTG GACAGCTTGT GGACTCTATT 
GCCAAGACAA GAGATGCTGG CTGTAGGCCA TACATGGCAC CTGAAAGAAT AGACCCAAGC 
GCATCACGAC AAGGATATGA TGTCCGCTCT GATGTCTGGA GTTTGGGGAT CACATTGTAT 
GAGTTGGCCA CAGGCCGATT TCCTTATCCA AAGTGGAATA GTGTATTTGA TCAACTAACA 
CAAGTCGTGA AAGGAGATCC TCCGCAGCTG AGTAATTCTG AGGAAAGGGA ATTCTCCCCG 
AGTTTCATCA ACTTTGTCAA CTTGTGCCTT ACGAAGGATG AATCCAAAAG GCCAAAGTAT 
AAAGAGCTTC TGAAACATCC CTTTATTTTG ATGTATGAAG AACGTGCCGT TGAGGTCGCA 
TGCTATGTTT GTAAAATCCT GGATCAAATG CCAGCTACTC CCAGCTCTCC CATGTATGTC 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( XM_005256753.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256810.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu49912
Clone ID Related Accession (Same CDS sequence)	XM_005256753.3 , XM_005256753.2
Accession Version	XM_005256753.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 846bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005256753.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCCACA AACCAAGTGG GCAAATAATG GCAGTTAAAA GAATTCGGTC AACAGTGGAT 
GAAAAAGAAC AAAAACAACT TCTTATGGAT TTGGATGTAG TAATGCGGAG TAGTGATTGC 
CCATACATTG TTCAGTTTTA TGGTGCACTC TTCAGAGAGG GTGACTGTTG GATCTGTATG 
GAACTCATGT CTACCTCGTT TGATAAGTTT TACAAATATG TATATAGTGT ATTAGATGAT 
GTTATTCCAG AAGAAATTTT AGGCAAAATC ACTTTAGCAA CTGTGAAAGC ACTAAACCAC 
TTAAAAGAAA ACTTGAAAAT TATTCACAGA GATATCAAAC CTTCCAATAT TCTTCTGGAC 
AGAAGTGGAA ATATTAAGCT CTGTGACTTC GGCATCAGTG GACAGCTTGT GGACTCTATT 
GCCAAGACAA GAGATGCTGG CTGTAGGCCA TACATGGCAC CTGAAAGAAT AGACCCAAGC 
GCATCACGAC AAGGATATGA TGTCCGCTCT GATGTCTGGA GTTTGGGGAT CACATTGTAT 
GAGTTGGCCA CAGGCCGATT TCCTTATCCA AAGTGGAATA GTGTATTTGA TCAACTAACA 
CAAGTCGTGA AAGGAGATCC TCCGCAGCTG AGTAATTCTG AGGAAAGGGA ATTCTCCCCG 
AGTTTCATCA ACTTTGTCAA CTTGTGCCTT ACGAAGGATG AATCCAAAAG GCCAAAGTAT 
AAAGAGCTTC TGAAACATCC CTTTATTTTG ATGTATGAAG AACGTGCCGT TGAGGTCGCA 
TGCTATGTTT GTAAAATCCT GGATCAAATG CCAGCTACTC CCAGCTCTCC CATGTATGTC 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256810.1
CDS	263..1108
Translation	MVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	XM_005256753.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256753.2

ORF Insert Sequence:

ATGGTCCACA AACCAAGTGG GCAAATAATG GCAGTTAAAA GAATTCGGTC AACAGTGGAT 
GAAAAAGAAC AAAAACAACT TCTTATGGAT TTGGATGTAG TAATGCGGAG TAGTGATTGC 
CCATACATTG TTCAGTTTTA TGGTGCACTC TTCAGAGAGG GTGACTGTTG GATCTGTATG 
GAACTCATGT CTACCTCGTT TGATAAGTTT TACAAATATG TATATAGTGT ATTAGATGAT 
GTTATTCCAG AAGAAATTTT AGGCAAAATC ACTTTAGCAA CTGTGAAAGC ACTAAACCAC 
TTAAAAGAAA ACTTGAAAAT TATTCACAGA GATATCAAAC CTTCCAATAT TCTTCTGGAC 
AGAAGTGGAA ATATTAAGCT CTGTGACTTC GGCATCAGTG GACAGCTTGT GGACTCTATT 
GCCAAGACAA GAGATGCTGG CTGTAGGCCA TACATGGCAC CTGAAAGAAT AGACCCAAGC 
GCATCACGAC AAGGATATGA TGTCCGCTCT GATGTCTGGA GTTTGGGGAT CACATTGTAT 
GAGTTGGCCA CAGGCCGATT TCCTTATCCA AAGTGGAATA GTGTATTTGA TCAACTAACA 
CAAGTCGTGA AAGGAGATCC TCCGCAGCTG AGTAATTCTG AGGAAAGGGA ATTCTCCCCG 
AGTTTCATCA ACTTTGTCAA CTTGTGCCTT ACGAAGGATG AATCCAAAAG GCCAAAGTAT 
AAAGAGCTTC TGAAACATCC CTTTATTTTG ATGTATGAAG AACGTGCCGT TGAGGTCGCA 
TGCTATGTTT GTAAAATCCT GGATCAAATG CCAGCTACTC CCAGCTCTCC CATGTATGTC 
GATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( XM_005256755.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256812.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu49913
Clone ID Related Accession (Same CDS sequence)	XM_005256755.2 , XM_011523977.2
Accession Version	XM_005256755.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005256755.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATTTGG ATGTAGTAAT GCGGAGTAGT GATTGCCCAT ACATTGTTCA GTTTTATGGT 
GCACTCTTCA GAGAGGGTGA CTGTTGGATC TGTATGGAAC TCATGTCTAC CTCGTTTGAT 
AAGTTTTACA AATATGTATA TAGTGTATTA GATGATGTTA TTCCAGAAGA AATTTTAGGC 
AAAATCACTT TAGCAACTGT GAAAGCACTA AACCACTTAA AAGAAAACTT GAAAATTATT 
CACAGAGATA TCAAACCTTC CAATATTCTT CTGGACAGAA GTGGAAATAT TAAGCTCTGT 
GACTTCGGCA TCAGTGGACA GCTTGTGGAC TCTATTGCCA AGACAAGAGA TGCTGGCTGT 
AGGCCATACA TGGCACCTGA AAGAATAGAC CCAAGCGCAT CACGACAAGG ATATGATGTC 
CGCTCTGATG TCTGGAGTTT GGGGATCACA TTGTATGAGT TGGCCACAGG CCGATTTCCT 
TATCCAAAGT GGAATAGTGT ATTTGATCAA CTAACACAAG TCGTGAAAGG AGATCCTCCG 
CAGCTGAGTA ATTCTGAGGA AAGGGAATTC TCCCCGAGTT TCATCAACTT TGTCAACTTG 
TGCCTTACGA AGGATGAATC CAAAAGGCCA AAGTATAAAG AGCTTCTGAA ACATCCCTTT 
ATTTTGATGT ATGAAGAACG TGCCGTTGAG GTCGCATGCT ATGTTTGTAA AATCCTGGAT 
CAAATGCCAG CTACTCCCAG CTCTCCCATG TATGTCGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256812.1
CDS	329..1090
Translation	MDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	XM_005256755.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256755.2

ORF Insert Sequence:

ATGGATTTGG ATGTAGTAAT GCGGAGTAGT GATTGCCCAT ACATTGTTCA GTTTTATGGT 
GCACTCTTCA GAGAGGGTGA CTGTTGGATC TGTATGGAAC TCATGTCTAC CTCGTTTGAT 
AAGTTTTACA AATATGTATA TAGTGTATTA GATGATGTTA TTCCAGAAGA AATTTTAGGC 
AAAATCACTT TAGCAACTGT GAAAGCACTA AACCACTTAA AAGAAAACTT GAAAATTATT 
CACAGAGATA TCAAACCTTC CAATATTCTT CTGGACAGAA GTGGAAATAT TAAGCTCTGT 
GACTTCGGCA TCAGTGGACA GCTTGTGGAC TCTATTGCCA AGACAAGAGA TGCTGGCTGT 
AGGCCATACA TGGCACCTGA AAGAATAGAC CCAAGCGCAT CACGACAAGG ATATGATGTC 
CGCTCTGATG TCTGGAGTTT GGGGATCACA TTGTATGAGT TGGCCACAGG CCGATTTCCT 
TATCCAAAGT GGAATAGTGT ATTTGATCAA CTAACACAAG TCGTGAAAGG AGATCCTCCG 
CAGCTGAGTA ATTCTGAGGA AAGGGAATTC TCCCCGAGTT TCATCAACTT TGTCAACTTG 
TGCCTTACGA AGGATGAATC CAAAAGGCCA AAGTATAAAG AGCTTCTGAA ACATCCCTTT 
ATTTTGATGT ATGAAGAACG TGCCGTTGAG GTCGCATGCT ATGTTTGTAA AATCCTGGAT 
CAAATGCCAG CTACTCCCAG CTCTCCCATG TATGTCGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( XM_011523977.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522279.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu49913
Clone ID Related Accession (Same CDS sequence)	XM_005256755.2 , XM_011523977.2
Accession Version	XM_011523977.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011523977.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATTTGG ATGTAGTAAT GCGGAGTAGT GATTGCCCAT ACATTGTTCA GTTTTATGGT 
GCACTCTTCA GAGAGGGTGA CTGTTGGATC TGTATGGAAC TCATGTCTAC CTCGTTTGAT 
AAGTTTTACA AATATGTATA TAGTGTATTA GATGATGTTA TTCCAGAAGA AATTTTAGGC 
AAAATCACTT TAGCAACTGT GAAAGCACTA AACCACTTAA AAGAAAACTT GAAAATTATT 
CACAGAGATA TCAAACCTTC CAATATTCTT CTGGACAGAA GTGGAAATAT TAAGCTCTGT 
GACTTCGGCA TCAGTGGACA GCTTGTGGAC TCTATTGCCA AGACAAGAGA TGCTGGCTGT 
AGGCCATACA TGGCACCTGA AAGAATAGAC CCAAGCGCAT CACGACAAGG ATATGATGTC 
CGCTCTGATG TCTGGAGTTT GGGGATCACA TTGTATGAGT TGGCCACAGG CCGATTTCCT 
TATCCAAAGT GGAATAGTGT ATTTGATCAA CTAACACAAG TCGTGAAAGG AGATCCTCCG 
CAGCTGAGTA ATTCTGAGGA AAGGGAATTC TCCCCGAGTT TCATCAACTT TGTCAACTTG 
TGCCTTACGA AGGATGAATC CAAAAGGCCA AAGTATAAAG AGCTTCTGAA ACATCCCTTT 
ATTTTGATGT ATGAAGAACG TGCCGTTGAG GTCGCATGCT ATGTTTGTAA AATCCTGGAT 
CAAATGCCAG CTACTCCCAG CTCTCCCATG TATGTCGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522279.1
CDS	219..980
Translation	MDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD

Target ORF information:

RefSeq Version	XM_011523977.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011523977.2

ORF Insert Sequence:

ATGGATTTGG ATGTAGTAAT GCGGAGTAGT GATTGCCCAT ACATTGTTCA GTTTTATGGT 
GCACTCTTCA GAGAGGGTGA CTGTTGGATC TGTATGGAAC TCATGTCTAC CTCGTTTGAT 
AAGTTTTACA AATATGTATA TAGTGTATTA GATGATGTTA TTCCAGAAGA AATTTTAGGC 
AAAATCACTT TAGCAACTGT GAAAGCACTA AACCACTTAA AAGAAAACTT GAAAATTATT 
CACAGAGATA TCAAACCTTC CAATATTCTT CTGGACAGAA GTGGAAATAT TAAGCTCTGT 
GACTTCGGCA TCAGTGGACA GCTTGTGGAC TCTATTGCCA AGACAAGAGA TGCTGGCTGT 
AGGCCATACA TGGCACCTGA AAGAATAGAC CCAAGCGCAT CACGACAAGG ATATGATGTC 
CGCTCTGATG TCTGGAGTTT GGGGATCACA TTGTATGAGT TGGCCACAGG CCGATTTCCT 
TATCCAAAGT GGAATAGTGT ATTTGATCAA CTAACACAAG TCGTGAAAGG AGATCCTCCG 
CAGCTGAGTA ATTCTGAGGA AAGGGAATTC TCCCCGAGTT TCATCAACTT TGTCAACTTG 
TGCCTTACGA AGGATGAATC CAAAAGGCCA AAGTATAAAG AGCTTCTGAA ACATCCCTTT 
ATTTTGATGT ATGAAGAACG TGCCGTTGAG GTCGCATGCT ATGTTTGTAA AATCCTGGAT 
CAAATGCCAG CTACTCCCAG CTCTCCCATG TATGTCGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K4 ( XM_011523976.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011522278.1 Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X3, mRNA.

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CloneID	OHu60445
Clone ID Related Accession (Same CDS sequence)	XM_011523976.2
Accession Version	XM_011523976.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 960bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011523976.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGCTTT 
CAGATAAACT TCTGTGAAAA GGCACAAAGT AAACGCAAAG CACTGAAGTT GAATTTTGCA 
AATCCACCTT TCAAATCTAC AGCAAGGTTT ACTCTGAATC CCAATCCTAC AGGAGTTCAA 
AACCCACACA TAGAGAGACT GAGAACACAC AGCATTGAGT CATCAGGAAA ACTGAAGATC 
TCCCCTGAAC AACACTGGGA TTTCACTGCA GAGGACTTGA AAGACCTTGG AGAAATTGGA 
CGAGGAGCTT ATGGTTCTGT CAACAAAATG GTCCACAAAC CAAGTGGGCA AATAATGGCA 
GTTAAAAGAA TTCGGTCAAC AGTGGATGAA AAAGAACAAA AACAACTTCT TATGGATTTG 
GATGTAGTAA TGCGGAGTAG TGATTGCCCA TACATTGTTC AGTTTTATGG TGCACTCTTC 
AGAGAGGGTG ACTGTTGGAT CTGTATGGAA CTCATGTCTA CCTCGTTTGA TAAGTTTTAC 
AAATATGTAT ATAGTGTATT AGATGATGTT ATTCCAGAAG AAATTTTAGG CAAAATCACT 
TTAGCAACTG TGAAAGCACT AAACCACTTA AAAGAAAACT TGAAAATTAT TCACAGAGAT 
ATCAAACCTT CCAATATTCT TCTGGACAGA AGTGGAAATA TTAAGCTCTG TGACTTCGGC 
ATCAGTGGAC AGCTTGTGGA CTCTATTGCC AAGACAAGAG ATGCTGGCTG TAGGCCATAC 
ATGGCACCTG AAAGAATAGA CCCAAGCGCA TCACGACAAG GATATGATGT CCGCTCTGAT 
GTCTGGAGTT TGGGGATCAC ATTGATAATA GGAGTCAACT ATTATCTGCA ACTGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011522278.1
CDS	54..1013
Translation	MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFANPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLIIGVNYYLQLH

Target ORF information:

RefSeq Version	XM_011523976.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 4 (MAP2K4), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011523976.2

ORF Insert Sequence:

ATGGCGGCTC CGAGCCCGAG CGGCGGCGGC GGCTCCGGGG GCGGCAGCGG CAGCGGCACC 
CCCGGCCCCG TAGGGTCCCC GGCGCCAGGC CACCCGGCCG TCAGCAGCAT GCAGGGCTTT 
CAGATAAACT TCTGTGAAAA GGCACAAAGT AAACGCAAAG CACTGAAGTT GAATTTTGCA 
AATCCACCTT TCAAATCTAC AGCAAGGTTT ACTCTGAATC CCAATCCTAC AGGAGTTCAA 
AACCCACACA TAGAGAGACT GAGAACACAC AGCATTGAGT CATCAGGAAA ACTGAAGATC 
TCCCCTGAAC AACACTGGGA TTTCACTGCA GAGGACTTGA AAGACCTTGG AGAAATTGGA 
CGAGGAGCTT ATGGTTCTGT CAACAAAATG GTCCACAAAC CAAGTGGGCA AATAATGGCA 
GTTAAAAGAA TTCGGTCAAC AGTGGATGAA AAAGAACAAA AACAACTTCT TATGGATTTG 
GATGTAGTAA TGCGGAGTAG TGATTGCCCA TACATTGTTC AGTTTTATGG TGCACTCTTC 
AGAGAGGGTG ACTGTTGGAT CTGTATGGAA CTCATGTCTA CCTCGTTTGA TAAGTTTTAC 
AAATATGTAT ATAGTGTATT AGATGATGTT ATTCCAGAAG AAATTTTAGG CAAAATCACT 
TTAGCAACTG TGAAAGCACT AAACCACTTA AAAGAAAACT TGAAAATTAT TCACAGAGAT 
ATCAAACCTT CCAATATTCT TCTGGACAGA AGTGGAAATA TTAAGCTCTG TGACTTCGGC 
ATCAGTGGAC AGCTTGTGGA CTCTATTGCC AAGACAAGAG ATGCTGGCTG TAGGCCATAC 
ATGGCACCTG AAAGAATAGA CCCAAGCGCA TCACGACAAG GATATGATGT CCGCTCTGAT 
GTCTGGAGTT TGGGGATCAC ATTGATAATA GGAGTCAACT ATTATCTGCA ACTGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	MAP2K4
Entrez Gene ID	6416
Full Name	mitogen-activated protein kinase kinase 4
Synonyms	JNKK,JNKK1,MAPKK4,MEK4,MKK4,PRKMK4,SAPKK-1,SAPKK1,SEK1,SERK1,SKK1
General protein information	Preferred Names mitogen-activated protein kinase kinase 4 Names dual specificity mitogen-activated protein kinase kinase 4 JNK-activated kinase 1 JNK-activating kinase 1 MAP kinase kinase 4 MAPK/ERK kinase 4 MAPKK 4 MEK 4 SAPK/ERK kinase 1 c-Jun N-terminal kinase kinase 1 stress-activated protein kinase kinase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p12
Summary	This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
Disorder MIM:	601335

Mus musculus (house mouse)	Map2k4	NP_033183.1
Drosophila melanogaster (fruit fly)	Mkk4	NP_001163551.1
Canis lupus familiaris (dog)	MAP2K4	XP_005620383.1
Bos taurus (cattle)	MAP2K4	NP_001092508.1
Rattus norvegicus (Norway rat)	Map2k4	NP_001025194.1
Danio rerio (zebrafish)	map2k4a	NP_991299.2
Homo sapiens (human)	MAP2K4	NP_001268364.1
Pan troglodytes (chimpanzee)	MAP2K4	XP_001163981.1
	MAP2K4	XP_001114292.1
Gallus gallus (chicken)	MAP2K4	XP_415583.4
Xenopus tropicalis (tropical clawed frog)	map2k4	NP_001107157.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003365	XP_314266.5
Schizosaccharomyces pombe (fission yeast)	wis1	NP_595457.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

MAP2K4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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