SMOC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SMOC1
Entrez Gene ID	64093
Full Name	SPARC related modular calcium binding 1
Synonyms	OAS
General protein information	Preferred Names SPARC related modular calcium binding 1 Names SPARC-related modular calcium-binding protein 1 secreted modular calcium-binding protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q24.2
Summary	This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
Disorder MIM:	608488
Disorder Html:	Microphthalmia with limb anomalies, 206920 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_022137.6	NP_071420.1	SPARC-related modular calcium-binding protein 1 isoform 2 precursor
XM_005267996.1	XP_005268053.1	SPARC-related modular calcium-binding protein 1 isoform X2
NM_001034852.2	NP_001030024.1	SPARC-related modular calcium-binding protein 1 isoform 1 precursor
NM_001034852.3	NP_001030024.1	SPARC-related modular calcium-binding protein 1 isoform 1 precursor
XM_005267995.1	XP_005268052.1	SPARC-related modular calcium-binding protein 1 isoform X1
NM_022137.5	NP_071420.1	SPARC-related modular calcium-binding protein 1 isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	SMOC1	NP_001030024.1
Pan troglodytes (chimpanzee)	SMOC1	XP_510036.4
Mus musculus (house mouse)	Smoc1	NP_001139689.1
Rattus norvegicus (Norway rat)	Smoc1	NP_001002835.1
Bos taurus (cattle)	SMOC1	NP_001073239.1
	LOC712994	XP_001110348.2
Canis lupus familiaris (dog)	SMOC1	XP_005623640.1
Gallus gallus (chicken)	SMOC1	XP_001231761.2
Danio rerio (zebrafish)	smoc1	NP_001188322.1
Xenopus tropicalis (tropical clawed frog)	smoc1	NP_001120579.1

Gene Ontology
Bibliography

Related articles in PubMed

A novel mutation in SMOC1 and variable phenotypic expression in two patients with Waardenburg anophthalmia syndrome.
Jamshidi J, Abdollahi S, Ghaedi H, Alehabib E, Tafakhori A, Alinaghi S, Chapi M, Johari AH, Darvish H
European journal of medical genetics60(11)578-582(2017 Nov)

A novel homozygous variant in the SMOC1 gene underlying Waardenburg anophthalmia syndrome.
Ullah A, Umair M, Ahmad F, Muhammad D, Basit S, Ahmad W
Ophthalmic genetics38(4)335-339(2017 Jul-Aug)

SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.
Thomas JT, Chhuy-Hy L, Andrykovich KR, Moos M Jr
PloS one11(4)e0154294(2016)

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, Han Y, Ran S, Hai R, Zhu XZ, Wu S, Yan H, Liu X, Yang TL, Guo Y, Zhang F, Guo YF, Chen Y, Chen X, Tan L, Zhang L, Deng FY, Deng H, Rivadeneira F, Duncan EL, Lee JY, Han BG, Cho NH, Nicholson GC, McCloskey E, Eastell R, Prince RL, Eisman JA, Jones G, Reid IR, Sambrook PN, Dennison EM, Danoy P, Yerges-Armstrong LM, Streeten EA, Hu T, Xiang S, Papasian CJ, Brown MA, Shin CS, Uitterlinden AG, Deng HW
Human molecular genetics23(7)1923-33(2014 Apr)

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.
Chimusa ER, Zaitlen N, Daya M, M?ller M, van Helden PD, Mulder NJ, Price AL, Hoal EG
Human molecular genetics23(3)796-809(2014 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Missense mutation in exon 3 of SMOC1 segregated with the Waardenburg anophthalmia syndrome in the ian family.
Title: A novel mutation in SMOC1 and variable phenotypic expression in two patients with Waardenburg anophthalmia syndrome.

This is the first report of Waardenburg anophthalmia syndrome (WAS) caused by a SMOC1 variant in a Pakistani population. The mutation identified in the present investigation extends the body of evidence implicating the gene SMOC-1 in causing WAS.
Title: A novel homozygous variant in the SMOC1 gene underlying Waardenburg anophthalmia syndrome.

SMOC binds to Pro-EGF, but does not induce Erk phosphorylation via the EGFR.
Title: SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.

SMOC1 provides a link between prenatal hormone exposure and digit ratio.
Title: Genetic association suggests that SMOC1 mediates between prenatal sex hormones and digit ratio.

IL-17A but not IL-22 suppresses the replication of hepatitis B virus by inducing the expression of MxA and OAS.
Title: IL-17A but not IL-22 suppresses the replication of hepatitis B virus mediated by over-expression of MxA and OAS mRNA in the HepG2.2.15 cell line.

The following SMOC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMOC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15591	NM_001034852.3 Latest version!	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu19209	NM_022137.6 Latest version!	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu47860	XM_005267995.1 Latest version!	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu47861	XM_005267996.1 Latest version!	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu15591	NM_001034852.2	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu19209	NM_022137.5	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SMOC1 ( NM_001034852.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001030024.1 Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15591
Clone ID Related Accession (Same CDS sequence)	NM_001034852.2 , NM_001034852.3
Accession Version	NM_001034852.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	SPARC-related modular calcium-binding protein 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA805236.1, BC011548.1, AJ249900.1, AK098441.1 and BQ183777.1. On Mar 10, 2011 this sequence version replaced NM_001034852.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289988.1, BC011548.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GTAGGACGCC TCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030024.1
CDS	283..1590
Translation	MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEVGRLV

Target ORF information:

RefSeq Version	NM_001034852.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034852.2

ORF Insert Sequence:

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GTAGGACGCC TCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMOC1 ( NM_001034852.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001030024.1 Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15591
Clone ID Related Accession (Same CDS sequence)	NM_001034852.2 , NM_001034852.3
Accession Version	NM_001034852.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-28
Organism	Homo sapiens(human)
Product	SPARC-related modular calcium-binding protein 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA805236.1, BC011548.1, AJ249900.1, AK098441.1 and BQ183777.1. On Jun 2, 2019 this sequence version replaced NM_001034852.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289988.1, BC011548.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GTAGGACGCC TCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030024.1
CDS	264..1571
Translation	MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEVGRLV

Target ORF information:

RefSeq Version	NM_001034852.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034852.3

ORF Insert Sequence:

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GTAGGACGCC TCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMOC1 ( NM_022137.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_071420.1 Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu19209
Clone ID Related Accession (Same CDS sequence)	NM_022137.6 , NM_022137.5
Accession Version	NM_022137.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1305bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-28
Organism	Homo sapiens(human)
Product	SPARC-related modular calcium-binding protein 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA805236.1, BC011548.1, BC008608.1, AK289988.1, AJ249900.1, AK098441.1 and BQ183777.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_022137.5. Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site at the 3' terminal exon compared to variant 1. This results in an isoform (2) that is 1 aa shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249900.1, SRR1803613.169064.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GGACGCCTCG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071420.1
CDS	264..1568
Translation	MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGRLV

Target ORF information:

RefSeq Version	NM_022137.6
Organism	Homo sapiens(human)
Definition	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022137.6

ORF Insert Sequence:

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GGACGCCTCG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMOC1 ( NM_022137.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_071420.1 Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 2, mRNA.

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CloneID	OHu19209
Clone ID Related Accession (Same CDS sequence)	NM_022137.6 , NM_022137.5
Accession Version	NM_022137.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1305bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	SPARC-related modular calcium-binding protein 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA805236.1, BC011548.1, BC008608.1, AK289988.1, AJ249900.1, AK098441.1 and BQ183777.1. This sequence is a reference standard in the RefSeqGene project. On Mar 10, 2011 this sequence version replaced NM_022137.4. Transcript Variant: This variant (2) uses an alternate in-frame acceptor splice site at the 3' terminal exon compared to variant 1. This results in an isoform (2) that is 1 aa shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ249900.1, SRR1660805.176033.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GGACGCCTCG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071420.1
CDS	283..1587
Translation	MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGRLV

Target ORF information:

RefSeq Version	NM_022137.5
Organism	Homo sapiens(human)
Definition	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022137.5

ORF Insert Sequence:

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGATGA CGGGTCTAAG 
CCGACACCCA CGATGGAGAC CCAGCCGGTG TTCGATGGAG ATGAAATCAC AGCCCCAACT 
CTATGGATTA AACACTTGGT GATCAAGGAC TCCAAACTGA ACAACACCAA CATAAGAAAT 
TCAGAGAAAG TCTATTCGTG TGACCAGGAG AGGCAGAGTG CCCTGGAAGA GGCCCAGCAG 
AATCCCCGTG AGGGTATTGT CATCCCTGAA TGTGCCCCTG GGGGACTCTA TAAGCCAGTG 
CAATGCCACC AGTCCACTGG CTACTGCTGG TGTGTGCTGG TGGACACAGG GCGCCCGCTG 
CCTGGGACCT CCACACGCTA CGTGATGCCC AGTTGTGAGA GCGACGCCAG GGCCAAGACT 
ACAGAGGCGG ATGACCCCTT CAAGGACAGG GAGCTACCAG GCTGTCCAGA AGGGAAGAAA 
ATGGAGTTTA TCACCAGCCT ACTGGATGCT CTCACCACTG ACATGGTTCA GGCCATTAAC 
TCAGCAGCGC CCACTGGAGG TGGGAGGTTC TCAGAGCCAG ACCCCAGCCA CACCCTGGAG 
GAGCGGGTAG TGCACTGGTA TTTCAGCCAG CTGGACAGCA ATAGCAGCAA CGACATTAAC 
AAGCGGGAGA TGAAGCCCTT CAAGCGCTAC GTGAAGAAGA AAGCCAAGCC CAAGAAATGT 
GCCCGGCGTT TCACCGACTA CTGTGACCTG AACAAAGACA AGGTCATTTC ACTGCCTGAG 
CTGAAGGGCT GCCTGGGTGT TAGCAAAGAA GGACGCCTCG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMOC1 ( XM_005267995.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268052.1 Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant X1, mRNA.

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CloneID	OHu47860
Clone ID Related Accession (Same CDS sequence)	XM_005267995.1
Accession Version	XM_005267995.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1341bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	SPARC-related modular calcium-binding protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGTCTC CTTTCGATTC 
TTTTTAACCC TCAATTCAGA TGACGGGTCT AAGCCGACAC CCACGATGGA GACCCAGCCG 
GTGTTCGATG GAGATGAAAT CACAGCCCCA ACTCTATGGA TTAAACACTT GGTGATCAAG 
GACTCCAAAC TGAACAACAC CAACATAAGA AATTCAGAGA AAGTCTATTC GTGTGACCAG 
GAGAGGCAGA GTGCCCTGGA AGAGGCCCAG CAGAATCCCC GTGAGGGTAT TGTCATCCCT 
GAATGTGCCC CTGGGGGACT CTATAAGCCA GTGCAATGCC ACCAGTCCAC TGGCTACTGC 
TGGTGTGTGC TGGTGGACAC AGGGCGCCCG CTGCCTGGGA CCTCCACACG CTACGTGATG 
CCCAGTTGTG AGAGCGACGC CAGGGCCAAG ACTACAGAGG CGGATGACCC CTTCAAGGAC 
AGGGAGCTAC CAGGCTGTCC AGAAGGGAAG AAAATGGAGT TTATCACCAG CCTACTGGAT 
GCTCTCACCA CTGACATGGT TCAGGCCATT AACTCAGCAG CGCCCACTGG AGGTGGGAGG 
TTCTCAGAGC CAGACCCCAG CCACACCCTG GAGGAGCGGG TAGTGCACTG GTATTTCAGC 
CAGCTGGACA GCAATAGCAG CAACGACATT AACAAGCGGG AGATGAAGCC CTTCAAGCGC 
TACGTGAAGA AGAAAGCCAA GCCCAAGAAA TGTGCCCGGC GTTTCACCGA CTACTGTGAC 
CTGAACAAAG ACAAGGTCAT TTCACTGCCT GAGCTGAAGG GCTGCCTGGG TGTTAGCAAA 
GAAGTAGGAC GCCTCGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268052.1
CDS	292..1632
Translation	MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEVGRLV

Target ORF information:

RefSeq Version	XM_005267995.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267995.1

ORF Insert Sequence:

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGTCTC CTTTCGATTC 
TTTTTAACCC TCAATTCAGA TGACGGGTCT AAGCCGACAC CCACGATGGA GACCCAGCCG 
GTGTTCGATG GAGATGAAAT CACAGCCCCA ACTCTATGGA TTAAACACTT GGTGATCAAG 
GACTCCAAAC TGAACAACAC CAACATAAGA AATTCAGAGA AAGTCTATTC GTGTGACCAG 
GAGAGGCAGA GTGCCCTGGA AGAGGCCCAG CAGAATCCCC GTGAGGGTAT TGTCATCCCT 
GAATGTGCCC CTGGGGGACT CTATAAGCCA GTGCAATGCC ACCAGTCCAC TGGCTACTGC 
TGGTGTGTGC TGGTGGACAC AGGGCGCCCG CTGCCTGGGA CCTCCACACG CTACGTGATG 
CCCAGTTGTG AGAGCGACGC CAGGGCCAAG ACTACAGAGG CGGATGACCC CTTCAAGGAC 
AGGGAGCTAC CAGGCTGTCC AGAAGGGAAG AAAATGGAGT TTATCACCAG CCTACTGGAT 
GCTCTCACCA CTGACATGGT TCAGGCCATT AACTCAGCAG CGCCCACTGG AGGTGGGAGG 
TTCTCAGAGC CAGACCCCAG CCACACCCTG GAGGAGCGGG TAGTGCACTG GTATTTCAGC 
CAGCTGGACA GCAATAGCAG CAACGACATT AACAAGCGGG AGATGAAGCC CTTCAAGCGC 
TACGTGAAGA AGAAAGCCAA GCCCAAGAAA TGTGCCCGGC GTTTCACCGA CTACTGTGAC 
CTGAACAAAG ACAAGGTCAT TTCACTGCCT GAGCTGAAGG GCTGCCTGGG TGTTAGCAAA 
GAAGTAGGAC GCCTCGTCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SMOC1 ( XM_005267996.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268053.1 Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu47861
Clone ID Related Accession (Same CDS sequence)	XM_005267996.1
Accession Version	XM_005267996.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	SPARC-related modular calcium-binding protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGTCTC CTTTCGATTC 
TTTTTAACCC TCAATTCAGA TGACGGGTCT AAGCCGACAC CCACGATGGA GACCCAGCCG 
GTGTTCGATG GAGATGAAAT CACAGCCCCA ACTCTATGGA TTAAACACTT GGTGATCAAG 
GACTCCAAAC TGAACAACAC CAACATAAGA AATTCAGAGA AAGTCTATTC GTGTGACCAG 
GAGAGGCAGA GTGCCCTGGA AGAGGCCCAG CAGAATCCCC GTGAGGGTAT TGTCATCCCT 
GAATGTGCCC CTGGGGGACT CTATAAGCCA GTGCAATGCC ACCAGTCCAC TGGCTACTGC 
TGGTGTGTGC TGGTGGACAC AGGGCGCCCG CTGCCTGGGA CCTCCACACG CTACGTGATG 
CCCAGTTGTG AGAGCGACGC CAGGGCCAAG ACTACAGAGG CGGATGACCC CTTCAAGGAC 
AGGGAGCTAC CAGGCTGTCC AGAAGGGAAG AAAATGGAGT TTATCACCAG CCTACTGGAT 
GCTCTCACCA CTGACATGGT TCAGGCCATT AACTCAGCAG CGCCCACTGG AGGTGGGAGG 
TTCTCAGAGC CAGACCCCAG CCACACCCTG GAGGAGCGGG TAGTGCACTG GTATTTCAGC 
CAGCTGGACA GCAATAGCAG CAACGACATT AACAAGCGGG AGATGAAGCC CTTCAAGCGC 
TACGTGAAGA AGAAAGCCAA GCCCAAGAAA TGTGCCCGGC GTTTCACCGA CTACTGTGAC 
CTGAACAAAG ACAAGGTCAT TTCACTGCCT GAGCTGAAGG GCTGCCTGGG TGTTAGCAAA 
GAAGGACGCC TCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268053.1
CDS	292..1629
Translation	MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGRLV

Target ORF information:

RefSeq Version	XM_005267996.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267996.1

ORF Insert Sequence:

ATGCTGCCCG CGCGCTGCGC CCGCCTGCTC ACGCCCCACT TGCTGCTGGT GTTGGTGCAG 
CTGTCCCCTG CTCGCGGCCA CCGCACCACA GGCCCCAGGT TTCTAATAAG TGACCGTGAC 
CCACAGTGCA ACCTCCACTG CTCCAGGACT CAACCCAAAC CCATCTGTGC CTCTGATGGC 
AGGTCCTACG AGTCCATGTG TGAGTACCAG CGAGCCAAGT GCCGAGACCC GACCCTGGGC 
GTGGTGCATC GAGGTAGATG CAAAGATGCT GGCCAGAGCA AGTGTCGCCT GGAGCGGGCT 
CAAGCCCTGG AGCAAGCCAA GAAGCCTCAG GAAGCTGTGT TTGTCCCAGA GTGTGGCGAG 
GATGGCTCCT TTACCCAGGT GCAGTGCCAT ACTTACACTG GGTACTGCTG GTGTGTCACC 
CCGGATGGGA AGCCCATCAG TGGCTCTTCT GTGCAGAATA AAACTCCTGT ATGTTCAGGT 
TCAGTCACCG ACAAGCCCTT GAGCCAGGGT AACTCAGGAA GGAAAGTCTC CTTTCGATTC 
TTTTTAACCC TCAATTCAGA TGACGGGTCT AAGCCGACAC CCACGATGGA GACCCAGCCG 
GTGTTCGATG GAGATGAAAT CACAGCCCCA ACTCTATGGA TTAAACACTT GGTGATCAAG 
GACTCCAAAC TGAACAACAC CAACATAAGA AATTCAGAGA AAGTCTATTC GTGTGACCAG 
GAGAGGCAGA GTGCCCTGGA AGAGGCCCAG CAGAATCCCC GTGAGGGTAT TGTCATCCCT 
GAATGTGCCC CTGGGGGACT CTATAAGCCA GTGCAATGCC ACCAGTCCAC TGGCTACTGC 
TGGTGTGTGC TGGTGGACAC AGGGCGCCCG CTGCCTGGGA CCTCCACACG CTACGTGATG 
CCCAGTTGTG AGAGCGACGC CAGGGCCAAG ACTACAGAGG CGGATGACCC CTTCAAGGAC 
AGGGAGCTAC CAGGCTGTCC AGAAGGGAAG AAAATGGAGT TTATCACCAG CCTACTGGAT 
GCTCTCACCA CTGACATGGT TCAGGCCATT AACTCAGCAG CGCCCACTGG AGGTGGGAGG 
TTCTCAGAGC CAGACCCCAG CCACACCCTG GAGGAGCGGG TAGTGCACTG GTATTTCAGC 
CAGCTGGACA GCAATAGCAG CAACGACATT AACAAGCGGG AGATGAAGCC CTTCAAGCGC 
TACGTGAAGA AGAAAGCCAA GCCCAAGAAA TGTGCCCGGC GTTTCACCGA CTACTGTGAC 
CTGAACAAAG ACAAGGTCAT TTCACTGCCT GAGCTGAAGG GCTGCCTGGG TGTTAGCAAA 
GAAGGACGCC TCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel mutation in SMOC1 and variable phenotypic expression in two patients with Waardenburg anophthalmia syndrome.
European journal of medical genetics60(11)578-582(2017 Nov)
Jamshidi J,Abdollahi S,Ghaedi H,Alehabib E,Tafakhori A,Alinaghi S,Chapi M,Johari AH,Darvish H

A novel homozygous variant in the SMOC1 gene underlying Waardenburg anophthalmia syndrome.
Ophthalmic genetics38(4)335-339(2017 Jul-Aug)
Ullah A,Umair M,Ahmad F,Muhammad D,Basit S,Ahmad W

SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.
PloS one11(4)e0154294(2016)
Thomas JT,Chhuy-Hy L,Andrykovich KR,Moos M Jr

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
Human molecular genetics23(7)1923-33(2014 Apr)
Zhang L,Choi HJ,Estrada K,Leo PJ,Li J,Pei YF,Zhang Y,Lin Y,Shen H,Liu YZ,Liu Y,Zhao Y,Zhang JG,Tian Q,Wang YP,Han Y,Ran S,Hai R,Zhu XZ,Wu S,Yan H,Liu X,Yang TL,Guo Y,Zhang F,Guo YF,Chen Y,Chen X,Tan L,Zhang L,Deng FY,Deng H,Rivadeneira F,Duncan EL,Lee JY,Han BG,Cho NH,Nicholson GC,McCloskey E,Eastell R,Prince RL,Eisman JA,Jones G,Reid IR,Sambrook PN,Dennison EM,Danoy P,Yerges-Armstrong LM,Streeten EA,Hu T,Xiang S,Papasian CJ,Brown MA,Shin CS,Uitterlinden AG,Deng HW

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.
Human molecular genetics23(3)796-809(2014 Feb)
Chimusa ER,Zaitlen N,Daya M,M?ller M,van Helden PD,Mulder NJ,Price AL,Hoal EG

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SMOC1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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