SEL1L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SEL1L
Entrez Gene ID	6400
Full Name	SEL1L ERAD E3 ligase adaptor subunit
Synonyms	PRO1063,SEL1-LIKE,SEL1L1
General protein information	Preferred Names SEL1L ERAD E3 ligase adaptor subunit Names protein sel-1 homolog 1 Suppressor of lin 12 (sel-1), C. elegans, homolog of sel-1 suppressor of lin-12-like 1 suppressor of lin-12-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q31.1
Summary	The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Disorder MIM:	602329

mRNA and Protein(s)

mRNA	Protein	Name
XM_005267988.2	XP_005268045.1	protein sel-1 homolog 1 isoform X1
XM_005267989.4	XP_005268046.1	protein sel-1 homolog 1 isoform X2
NM_005065.6	NP_005056.3	protein sel-1 homolog 1 isoform 1 precursor
XM_005267989.3	XP_005268046.1	protein sel-1 homolog 1 isoform X2
NM_001244984.1	NP_001231913.1	protein sel-1 homolog 1 isoform 2 precursor
XM_005267988.3	XP_005268045.1	protein sel-1 homolog 1 isoform X1
NM_005065.5	NP_005056.3	protein sel-1 homolog 1 isoform 1 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	SEL1L	NP_005056.3
Arabidopsis thaliana (thale cress)	AT1G18260	NP_564049.1
Pan troglodytes (chimpanzee)	SEL1L	XP_510102.3
Bos taurus (cattle)	SEL1L	NP_001193837.1
Gallus gallus (chicken)	SEL1L	XP_421303.2
Danio rerio (zebrafish)	sel1l	NP_001038629.1
Caenorhabditis elegans (roundworm)	sel-1	NP_506144.1
Rattus norvegicus (Norway rat)	Sel1l	NP_808794.2
Mus musculus (house mouse)	Sel1l	NP_001034178.1
Drosophila melanogaster (fruit fly)	Hrd3	NP_001262882.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000615	XP_310466.4
Arabidopsis thaliana (thale cress)	AT1G73570	NP_177498.1
Xenopus tropicalis (tropical clawed frog)	sel1l	XP_002938416.1
	SEL1L	XP_001105925.1
Canis lupus familiaris (dog)	SEL1L	XP_537530.2
Oryza sativa (rice)	Os03g0259300	NP_001049611.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2.
Choi SI, Lee E, Jeong JB, Akuzum B, Maeng YS, Kim TI, Kim EK
Biochemical and biophysical research communications477(4)841-846(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Together, these results suggest that ER stress might comprise an important factor in GCD2 pathophysiology and that the effects of 4-PBA treatment might have important implications for the development of GCD2 therapeutics.
Title: 4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2.

The SEL1L critically regulates HRD1-mediated disposal of misfolded cargo through its short membrane spanning stretch.
Title: Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.

this is the first study reporting a significant association of the SEL1L SNP rs12435998 constitutive genetic variant with an improved overall survival in glioblastoma multiforme patients
Title: SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.

SEL1L down-modulation synergy enhances valporic acid cytotoxic effects by influencing glioma stem cells proliferation and self-renewal properties.
Title: Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.

Data revealed close interaction of these two proteins in regulating the cross-talk between extracellular matrix and insulin signalling to create a favourable micro-environment for ss-cell development and function.
Title: SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling.

The following SEL1L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEL1L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19523	NM_005065.6 Latest version!	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu15895	NM_001244984.1 Latest version!	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu47855	XM_005267988.3 Latest version!	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu47856	XM_005267989.4 Latest version!	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu47856	XM_005267989.3	Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu47855	XM_005267988.2	Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu19523	NM_005065.5	Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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Reference Sequences (Refseq)

SEL1L ( NM_005065.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_005056.3 Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19523
Clone ID Related Accession (Same CDS sequence)	NM_005065.6 , NM_005065.5
Accession Version	NM_005065.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP358857.1, AB020335.1, AF052059.1, BC040498.1, ES313707.1, DA833312.1, DA351814.1, CB986742.1 and CA447094.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_005065.5. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.251455.1, SRR1803614.1215.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000336735.9/ ENSP00000337053.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGAGAGC ATTTGACTAC 
TTCAATTTAG CAGCAAATGC TGGCAATTCA CATGCCATGG CCTTTTTGGG AAAGATGTAT 
TCGGAAGGAA GTGACATTGT ACCTCAGAGT AATGAGACAG CTCTCCACTA CTTTAAGAAA 
GCTGCTGACA TGGGCAACCC AGTTGGACAG AGTGGGCTTG GAATGGCCTA CCTCTATGGG 
AGAGGAGTTC AAGTTAATTA TGATCTAGCC CTTAAGTATT TCCAGAAAGC TGCTGAACAA 
GGCTGGGTGG ATGGGCAGCT ACAGCTTGGT TCCATGTACT ATAATGGCAT TGGAGTCAAG 
AGAGATTATA AACAGGCCTT GAAGTATTTT AATTTAGCTT CTCAGGGAGG CCATATCTTG 
GCTTTCTATA ACCTAGCTCA GATGCATGCC AGTGGCACCG GCGTGATGCG ATCATGTCAC 
ACTGCAGTGG AGTTGTTTAA GAATGTATGT GAACGAGGCC GTTGGTCTGA AAGGCTTATG 
ACTGCCTATA ACAGCTATAA AGATGGCGAT TACAATGCTG CAGTGATCCA GTACCTCCTC 
CTGGCTGAAC AGGGCTATGA AGTGGCACAA AGCAATGCAG CCTTTATTCT TGATCAGAGA 
GAAGCAAGCA TTGTAGGTGA GAATGAAACT TATCCCAGAG CTTTGCTACA TTGGAACAGG 
GCCGCCTCTC AAGGCTATAC TGTGGCTAGA ATTAAGCTCG GAGACTACCA TTTCTATGGG 
TTTGGCACCG ATGTAGATTA TGAAACTGCA TTTATTCATT ACCGTCTGGC TTCTGAGCAG 
CAACACAGTG CACAAGCTAT GTTTAATCTG GGATATATGC ATGAGAAAGG ACTGGGCATT 
AAACAGGATA TTCACCTTGC GAAACGTTTT TATGACATGG CAGCTGAAGC CAGCCCAGAT 
GCACAAGTTC CAGTCTTCCT AGCCCTCTGC AAATTGGGCG TCGTCTATTT CTTGCAGTAC 
ATACGGGAAA CAAACATTCG AGATATGTTC ACCCAACTTG ATATGGACCA GCTTTTGGGA 
CCTGAGTGGG ACCTTTACCT CATGACCATC ATTGCGCTGC TGTTGGGAAC AGTCATAGCT 
TACAGGCAAA GGCAGCACCA AGACATGCCT GCACCCAGGC CTCCAGGGCC ACGGCCAGCT 
CCACCCCAGC AGGAGGGGCC ACCAGAGCAG CAGCCACCAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005056.3
CDS	110..2494
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ

Target ORF information:

RefSeq Version	NM_005065.6
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005065.6

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGAGAGC ATTTGACTAC 
TTCAATTTAG CAGCAAATGC TGGCAATTCA CATGCCATGG CCTTTTTGGG AAAGATGTAT 
TCGGAAGGAA GTGACATTGT ACCTCAGAGT AATGAGACAG CTCTCCACTA CTTTAAGAAA 
GCTGCTGACA TGGGCAACCC AGTTGGACAG AGTGGGCTTG GAATGGCCTA CCTCTATGGG 
AGAGGAGTTC AAGTTAATTA TGATCTAGCC CTTAAGTATT TCCAGAAAGC TGCTGAACAA 
GGCTGGGTGG ATGGGCAGCT ACAGCTTGGT TCCATGTACT ATAATGGCAT TGGAGTCAAG 
AGAGATTATA AACAGGCCTT GAAGTATTTT AATTTAGCTT CTCAGGGAGG CCATATCTTG 
GCTTTCTATA ACCTAGCTCA GATGCATGCC AGTGGCACCG GCGTGATGCG ATCATGTCAC 
ACTGCAGTGG AGTTGTTTAA GAATGTATGT GAACGAGGCC GTTGGTCTGA AAGGCTTATG 
ACTGCCTATA ACAGCTATAA AGATGGCGAT TACAATGCTG CAGTGATCCA GTACCTCCTC 
CTGGCTGAAC AGGGCTATGA AGTGGCACAA AGCAATGCAG CCTTTATTCT TGATCAGAGA 
GAAGCAAGCA TTGTAGGTGA GAATGAAACT TATCCCAGAG CTTTGCTACA TTGGAACAGG 
GCCGCCTCTC AAGGCTATAC TGTGGCTAGA ATTAAGCTCG GAGACTACCA TTTCTATGGG 
TTTGGCACCG ATGTAGATTA TGAAACTGCA TTTATTCATT ACCGTCTGGC TTCTGAGCAG 
CAACACAGTG CACAAGCTAT GTTTAATCTG GGATATATGC ATGAGAAAGG ACTGGGCATT 
AAACAGGATA TTCACCTTGC GAAACGTTTT TATGACATGG CAGCTGAAGC CAGCCCAGAT 
GCACAAGTTC CAGTCTTCCT AGCCCTCTGC AAATTGGGCG TCGTCTATTT CTTGCAGTAC 
ATACGGGAAA CAAACATTCG AGATATGTTC ACCCAACTTG ATATGGACCA GCTTTTGGGA 
CCTGAGTGGG ACCTTTACCT CATGACCATC ATTGCGCTGC TGTTGGGAAC AGTCATAGCT 
TACAGGCAAA GGCAGCACCA AGACATGCCT GCACCCAGGC CTCCAGGGCC ACGGCCAGCT 
CCACCCCAGC AGGAGGGGCC ACCAGAGCAG CAGCCACCAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEL1L ( NM_005065.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005056.3 Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19523
Clone ID Related Accession (Same CDS sequence)	NM_005065.6 , NM_005065.5
Accession Version	NM_005065.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP358857.1, AB020335.1, AF052059.1, BC040498.1, ES313707.1, DA833312.1, DA351814.1, CB986742.1 and CA447094.1. This sequence is a reference standard in the RefSeqGene project. On Oct 8, 2011 this sequence version replaced NM_005065.4. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.1215.1, SRR1803612.130500.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGAGAGC ATTTGACTAC 
TTCAATTTAG CAGCAAATGC TGGCAATTCA CATGCCATGG CCTTTTTGGG AAAGATGTAT 
TCGGAAGGAA GTGACATTGT ACCTCAGAGT AATGAGACAG CTCTCCACTA CTTTAAGAAA 
GCTGCTGACA TGGGCAACCC AGTTGGACAG AGTGGGCTTG GAATGGCCTA CCTCTATGGG 
AGAGGAGTTC AAGTTAATTA TGATCTAGCC CTTAAGTATT TCCAGAAAGC TGCTGAACAA 
GGCTGGGTGG ATGGGCAGCT ACAGCTTGGT TCCATGTACT ATAATGGCAT TGGAGTCAAG 
AGAGATTATA AACAGGCCTT GAAGTATTTT AATTTAGCTT CTCAGGGAGG CCATATCTTG 
GCTTTCTATA ACCTAGCTCA GATGCATGCC AGTGGCACCG GCGTGATGCG ATCATGTCAC 
ACTGCAGTGG AGTTGTTTAA GAATGTATGT GAACGAGGCC GTTGGTCTGA AAGGCTTATG 
ACTGCCTATA ACAGCTATAA AGATGGCGAT TACAATGCTG CAGTGATCCA GTACCTCCTC 
CTGGCTGAAC AGGGCTATGA AGTGGCACAA AGCAATGCAG CCTTTATTCT TGATCAGAGA 
GAAGCAAGCA TTGTAGGTGA GAATGAAACT TATCCCAGAG CTTTGCTACA TTGGAACAGG 
GCCGCCTCTC AAGGCTATAC TGTGGCTAGA ATTAAGCTCG GAGACTACCA TTTCTATGGG 
TTTGGCACCG ATGTAGATTA TGAAACTGCA TTTATTCATT ACCGTCTGGC TTCTGAGCAG 
CAACACAGTG CACAAGCTAT GTTTAATCTG GGATATATGC ATGAGAAAGG ACTGGGCATT 
AAACAGGATA TTCACCTTGC GAAACGTTTT TATGACATGG CAGCTGAAGC CAGCCCAGAT 
GCACAAGTTC CAGTCTTCCT AGCCCTCTGC AAATTGGGCG TCGTCTATTT CTTGCAGTAC 
ATACGGGAAA CAAACATTCG AGATATGTTC ACCCAACTTG ATATGGACCA GCTTTTGGGA 
CCTGAGTGGG ACCTTTACCT CATGACCATC ATTGCGCTGC TGTTGGGAAC AGTCATAGCT 
TACAGGCAAA GGCAGCACCA AGACATGCCT GCACCCAGGC CTCCAGGGCC ACGGCCAGCT 
CCACCCCAGC AGGAGGGGCC ACCAGAGCAG CAGCCACCAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005056.3
CDS	118..2502
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ

Target ORF information:

RefSeq Version	NM_005065.5
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005065.5

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGAGAGC ATTTGACTAC 
TTCAATTTAG CAGCAAATGC TGGCAATTCA CATGCCATGG CCTTTTTGGG AAAGATGTAT 
TCGGAAGGAA GTGACATTGT ACCTCAGAGT AATGAGACAG CTCTCCACTA CTTTAAGAAA 
GCTGCTGACA TGGGCAACCC AGTTGGACAG AGTGGGCTTG GAATGGCCTA CCTCTATGGG 
AGAGGAGTTC AAGTTAATTA TGATCTAGCC CTTAAGTATT TCCAGAAAGC TGCTGAACAA 
GGCTGGGTGG ATGGGCAGCT ACAGCTTGGT TCCATGTACT ATAATGGCAT TGGAGTCAAG 
AGAGATTATA AACAGGCCTT GAAGTATTTT AATTTAGCTT CTCAGGGAGG CCATATCTTG 
GCTTTCTATA ACCTAGCTCA GATGCATGCC AGTGGCACCG GCGTGATGCG ATCATGTCAC 
ACTGCAGTGG AGTTGTTTAA GAATGTATGT GAACGAGGCC GTTGGTCTGA AAGGCTTATG 
ACTGCCTATA ACAGCTATAA AGATGGCGAT TACAATGCTG CAGTGATCCA GTACCTCCTC 
CTGGCTGAAC AGGGCTATGA AGTGGCACAA AGCAATGCAG CCTTTATTCT TGATCAGAGA 
GAAGCAAGCA TTGTAGGTGA GAATGAAACT TATCCCAGAG CTTTGCTACA TTGGAACAGG 
GCCGCCTCTC AAGGCTATAC TGTGGCTAGA ATTAAGCTCG GAGACTACCA TTTCTATGGG 
TTTGGCACCG ATGTAGATTA TGAAACTGCA TTTATTCATT ACCGTCTGGC TTCTGAGCAG 
CAACACAGTG CACAAGCTAT GTTTAATCTG GGATATATGC ATGAGAAAGG ACTGGGCATT 
AAACAGGATA TTCACCTTGC GAAACGTTTT TATGACATGG CAGCTGAAGC CAGCCCAGAT 
GCACAAGTTC CAGTCTTCCT AGCCCTCTGC AAATTGGGCG TCGTCTATTT CTTGCAGTAC 
ATACGGGAAA CAAACATTCG AGATATGTTC ACCCAACTTG ATATGGACCA GCTTTTGGGA 
CCTGAGTGGG ACCTTTACCT CATGACCATC ATTGCGCTGC TGTTGGGAAC AGTCATAGCT 
TACAGGCAAA GGCAGCACCA AGACATGCCT GCACCCAGGC CTCCAGGGCC ACGGCCAGCT 
CCACCCCAGC AGGAGGGGCC ACCAGAGCAG CAGCCACCAC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEL1L ( NM_001244984.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231913.1 Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant 2, mRNA.

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CloneID	OHu15895
Clone ID Related Accession (Same CDS sequence)	NM_001244984.1
Accession Version	NM_001244984.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP358857.1 and AY358651.1. Transcript Variant: This variant (2) differs at the 3' end compared to variant 1. This results in a shorter isoform (2) with a distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358651.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGTAAGTAGA 
CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231913.1
CDS	118..1023
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLVSRL

Target ORF information:

RefSeq Version	NM_001244984.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244984.1

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGTAAGTAGA 
CTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEL1L ( XM_005267988.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268045.1 Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant X1, mRNA.

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CloneID	OHu47855
Clone ID Related Accession (Same CDS sequence)	XM_005267988.2 , XM_005267988.3
Accession Version	XM_005267988.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267988.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG ATAAGGAGTA TGATGAATGT 
ACATCAGATG GGAGGGAAGA TGGCAGACTG TGGTGTGCTA CAACCTATGA CTACAAAGCA 
GATGAAAAGT GGGGCTTTTG TGAAACTGAA GAAGAGGCTG CTAAGAGACG GCAGATGCAG 
GAAGCAGAAA TGATGTATCA AACTGGAATG AAAATCCTTA ATGGAAGCAA TAAGAAAAGC 
CAAAAAAGAG AAGCATATCG GTATCTCCAA AAGGCAGCAA GCATGAACCA TACCAAAGCC 
CTGGAGAGAG TGTCATATGC TCTTTTATTT GGTGATTACT TGCCACAGAA TATCCAGGCA 
GCGAGAGAGA TGTTTGAGAA GCTGACTGAG GAAGGCTCTC CCAAGGGACA GACTGCTCTT 
GGCTTTCTGT ATGCCTCTGG ACTTGGTGTT AATTCAAGTC AGGCAAAGGC TCTTGTATAT 
TATACATTTG GAGCTCTTGG GGGCAATCTA ATAGCCCACA TGGTTTTGGG TTACAGATAC 
TGGGCTGGCA TCGGCGTCCT CCAGAGTTGT GAATCTGCCC TGACTCACTA TCGTCTTGTT 
GCCAATCATG TTGCTAGTGA TATCTCGCTA ACAGGAGGCT CAGTAGTACA GAGAATACGG 
CTGCCTGATG AAGTGGAAAA TCCAGGAATG AACAGTGGAA TGCTAGAAGA AGATTTGATT 
CAATATTACC AGTTCCTAGC TGAAAAAGGT GATGTACAAG CACAGGTTGG TCTTGGACAA 
CTGCACCTGC ACGGAGGGCG TGGAGTAGAA CAGAATCATC AGAGAGCATT TGACTACTTC 
AATTTAGCAG CAAATGCTGG CAATTCACAT GCCATGGCCT TTTTGGGAAA GATGTATTCG 
GAAGGAAGTG ACATTGTACC TCAGAGTAAT GAGACAGCTC TCCACTACTT TAAGAAAGCT 
GCTGACATGG GCAACCCAGT TGGACAGAGT GGGCTTGGAA TGGCCTACCT CTATGGGAGA 
GGAGTTCAAG TTAATTATGA TCTAGCCCTT AAGTATTTCC AGAAAGCTGC TGAACAAGGC 
TGGGTGGATG GGCAGCTACA GCTTGGTTCC ATGTACTATA ATGGCATTGG AGTCAAGAGA 
GATTATAAAC AGGCCTTGAA GTATTTTAAT TTAGCTTCTC AGGGAGGCCA TATCTTGGCT 
TTCTATAACC TAGCTCAGAT GCATGCCAGT GGCACCGGCG TGATGCGATC ATGTCACACT 
GCAGTGGAGT TGTTTAAGAA TGTATGTGAA CGAGGCCGTT GGTCTGAAAG GCTTATGACT 
GCCTATAACA GCTATAAAGA TGGCGATTAC AATGCTGCAG TGATCCAGTA CCTCCTCCTG 
GCTGAACAGG GCTATGAAGT GGCACAAAGC AATGCAGCCT TTATTCTTGA TCAGAGAGAA 
GCAAGCATTG TAGGTGAGAA TGAAACTTAT CCCAGAGCTT TGCTACATTG GAACAGGGCC 
GCCTCTCAAG GCTATACTGT GGCTAGAATT AAGCTCGGAG ACTACCATTT CTATGGGTTT 
GGCACCGATG TAGATTATGA AACTGCATTT ATTCATTACC GTCTGGCTTC TGAGCAGCAA 
CACAGTGCAC AAGCTATGTT TAATCTGGGA TATATGCATG AGAAAGGACT GGGCATTAAA 
CAGGATATTC ACCTTGCGAA ACGTTTTTAT GACATGGCAG CTGAAGCCAG CCCAGATGCA 
CAAGTTCCAG TCTTCCTAGC CCTCTGCAAA TTGGGCGTCG TCTATTTCTT GCAGTACATA 
CGGGAAACAA ACATTCGAGA TATGTTCACC CAACTTGATA TGGACCAGCT TTTGGGACCT 
GAGTGGGACC TTTACCTCAT GACCATCATT GCGCTGCTGT TGGGAACAGT CATAGCTTAC 
AGGCAAAGGC AGCACCAAGA CATGCCTGCA CCCAGGCCTC CAGGGCCACG GCCAGCTCCA 
CCCCAGCAGG AGGGGCCACC AGAGCAGCAG CCACCACAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268045.1
CDS	64..2385
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ

Target ORF information:

RefSeq Version	XM_005267988.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267988.2

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG ATAAGGAGTA TGATGAATGT 
ACATCAGATG GGAGGGAAGA TGGCAGACTG TGGTGTGCTA CAACCTATGA CTACAAAGCA 
GATGAAAAGT GGGGCTTTTG TGAAACTGAA GAAGAGGCTG CTAAGAGACG GCAGATGCAG 
GAAGCAGAAA TGATGTATCA AACTGGAATG AAAATCCTTA ATGGAAGCAA TAAGAAAAGC 
CAAAAAAGAG AAGCATATCG GTATCTCCAA AAGGCAGCAA GCATGAACCA TACCAAAGCC 
CTGGAGAGAG TGTCATATGC TCTTTTATTT GGTGATTACT TGCCACAGAA TATCCAGGCA 
GCGAGAGAGA TGTTTGAGAA GCTGACTGAG GAAGGCTCTC CCAAGGGACA GACTGCTCTT 
GGCTTTCTGT ATGCCTCTGG ACTTGGTGTT AATTCAAGTC AGGCAAAGGC TCTTGTATAT 
TATACATTTG GAGCTCTTGG GGGCAATCTA ATAGCCCACA TGGTTTTGGG TTACAGATAC 
TGGGCTGGCA TCGGCGTCCT CCAGAGTTGT GAATCTGCCC TGACTCACTA TCGTCTTGTT 
GCCAATCATG TTGCTAGTGA TATCTCGCTA ACAGGAGGCT CAGTAGTACA GAGAATACGG 
CTGCCTGATG AAGTGGAAAA TCCAGGAATG AACAGTGGAA TGCTAGAAGA AGATTTGATT 
CAATATTACC AGTTCCTAGC TGAAAAAGGT GATGTACAAG CACAGGTTGG TCTTGGACAA 
CTGCACCTGC ACGGAGGGCG TGGAGTAGAA CAGAATCATC AGAGAGCATT TGACTACTTC 
AATTTAGCAG CAAATGCTGG CAATTCACAT GCCATGGCCT TTTTGGGAAA GATGTATTCG 
GAAGGAAGTG ACATTGTACC TCAGAGTAAT GAGACAGCTC TCCACTACTT TAAGAAAGCT 
GCTGACATGG GCAACCCAGT TGGACAGAGT GGGCTTGGAA TGGCCTACCT CTATGGGAGA 
GGAGTTCAAG TTAATTATGA TCTAGCCCTT AAGTATTTCC AGAAAGCTGC TGAACAAGGC 
TGGGTGGATG GGCAGCTACA GCTTGGTTCC ATGTACTATA ATGGCATTGG AGTCAAGAGA 
GATTATAAAC AGGCCTTGAA GTATTTTAAT TTAGCTTCTC AGGGAGGCCA TATCTTGGCT 
TTCTATAACC TAGCTCAGAT GCATGCCAGT GGCACCGGCG TGATGCGATC ATGTCACACT 
GCAGTGGAGT TGTTTAAGAA TGTATGTGAA CGAGGCCGTT GGTCTGAAAG GCTTATGACT 
GCCTATAACA GCTATAAAGA TGGCGATTAC AATGCTGCAG TGATCCAGTA CCTCCTCCTG 
GCTGAACAGG GCTATGAAGT GGCACAAAGC AATGCAGCCT TTATTCTTGA TCAGAGAGAA 
GCAAGCATTG TAGGTGAGAA TGAAACTTAT CCCAGAGCTT TGCTACATTG GAACAGGGCC 
GCCTCTCAAG GCTATACTGT GGCTAGAATT AAGCTCGGAG ACTACCATTT CTATGGGTTT 
GGCACCGATG TAGATTATGA AACTGCATTT ATTCATTACC GTCTGGCTTC TGAGCAGCAA 
CACAGTGCAC AAGCTATGTT TAATCTGGGA TATATGCATG AGAAAGGACT GGGCATTAAA 
CAGGATATTC ACCTTGCGAA ACGTTTTTAT GACATGGCAG CTGAAGCCAG CCCAGATGCA 
CAAGTTCCAG TCTTCCTAGC CCTCTGCAAA TTGGGCGTCG TCTATTTCTT GCAGTACATA 
CGGGAAACAA ACATTCGAGA TATGTTCACC CAACTTGATA TGGACCAGCT TTTGGGACCT 
GAGTGGGACC TTTACCTCAT GACCATCATT GCGCTGCTGT TGGGAACAGT CATAGCTTAC 
AGGCAAAGGC AGCACCAAGA CATGCCTGCA CCCAGGCCTC CAGGGCCACG GCCAGCTCCA 
CCCCAGCAGG AGGGGCCACC AGAGCAGCAG CCACCACAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEL1L ( XM_005267988.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268045.1 Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu47855
Clone ID Related Accession (Same CDS sequence)	XM_005267988.2 , XM_005267988.3
Accession Version	XM_005267988.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2322bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005267988.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG ATAAGGAGTA TGATGAATGT 
ACATCAGATG GGAGGGAAGA TGGCAGACTG TGGTGTGCTA CAACCTATGA CTACAAAGCA 
GATGAAAAGT GGGGCTTTTG TGAAACTGAA GAAGAGGCTG CTAAGAGACG GCAGATGCAG 
GAAGCAGAAA TGATGTATCA AACTGGAATG AAAATCCTTA ATGGAAGCAA TAAGAAAAGC 
CAAAAAAGAG AAGCATATCG GTATCTCCAA AAGGCAGCAA GCATGAACCA TACCAAAGCC 
CTGGAGAGAG TGTCATATGC TCTTTTATTT GGTGATTACT TGCCACAGAA TATCCAGGCA 
GCGAGAGAGA TGTTTGAGAA GCTGACTGAG GAAGGCTCTC CCAAGGGACA GACTGCTCTT 
GGCTTTCTGT ATGCCTCTGG ACTTGGTGTT AATTCAAGTC AGGCAAAGGC TCTTGTATAT 
TATACATTTG GAGCTCTTGG GGGCAATCTA ATAGCCCACA TGGTTTTGGG TTACAGATAC 
TGGGCTGGCA TCGGCGTCCT CCAGAGTTGT GAATCTGCCC TGACTCACTA TCGTCTTGTT 
GCCAATCATG TTGCTAGTGA TATCTCGCTA ACAGGAGGCT CAGTAGTACA GAGAATACGG 
CTGCCTGATG AAGTGGAAAA TCCAGGAATG AACAGTGGAA TGCTAGAAGA AGATTTGATT 
CAATATTACC AGTTCCTAGC TGAAAAAGGT GATGTACAAG CACAGGTTGG TCTTGGACAA 
CTGCACCTGC ACGGAGGGCG TGGAGTAGAA CAGAATCATC AGAGAGCATT TGACTACTTC 
AATTTAGCAG CAAATGCTGG CAATTCACAT GCCATGGCCT TTTTGGGAAA GATGTATTCG 
GAAGGAAGTG ACATTGTACC TCAGAGTAAT GAGACAGCTC TCCACTACTT TAAGAAAGCT 
GCTGACATGG GCAACCCAGT TGGACAGAGT GGGCTTGGAA TGGCCTACCT CTATGGGAGA 
GGAGTTCAAG TTAATTATGA TCTAGCCCTT AAGTATTTCC AGAAAGCTGC TGAACAAGGC 
TGGGTGGATG GGCAGCTACA GCTTGGTTCC ATGTACTATA ATGGCATTGG AGTCAAGAGA 
GATTATAAAC AGGCCTTGAA GTATTTTAAT TTAGCTTCTC AGGGAGGCCA TATCTTGGCT 
TTCTATAACC TAGCTCAGAT GCATGCCAGT GGCACCGGCG TGATGCGATC ATGTCACACT 
GCAGTGGAGT TGTTTAAGAA TGTATGTGAA CGAGGCCGTT GGTCTGAAAG GCTTATGACT 
GCCTATAACA GCTATAAAGA TGGCGATTAC AATGCTGCAG TGATCCAGTA CCTCCTCCTG 
GCTGAACAGG GCTATGAAGT GGCACAAAGC AATGCAGCCT TTATTCTTGA TCAGAGAGAA 
GCAAGCATTG TAGGTGAGAA TGAAACTTAT CCCAGAGCTT TGCTACATTG GAACAGGGCC 
GCCTCTCAAG GCTATACTGT GGCTAGAATT AAGCTCGGAG ACTACCATTT CTATGGGTTT 
GGCACCGATG TAGATTATGA AACTGCATTT ATTCATTACC GTCTGGCTTC TGAGCAGCAA 
CACAGTGCAC AAGCTATGTT TAATCTGGGA TATATGCATG AGAAAGGACT GGGCATTAAA 
CAGGATATTC ACCTTGCGAA ACGTTTTTAT GACATGGCAG CTGAAGCCAG CCCAGATGCA 
CAAGTTCCAG TCTTCCTAGC CCTCTGCAAA TTGGGCGTCG TCTATTTCTT GCAGTACATA 
CGGGAAACAA ACATTCGAGA TATGTTCACC CAACTTGATA TGGACCAGCT TTTGGGACCT 
GAGTGGGACC TTTACCTCAT GACCATCATT GCGCTGCTGT TGGGAACAGT CATAGCTTAC 
AGGCAAAGGC AGCACCAAGA CATGCCTGCA CCCAGGCCTC CAGGGCCACG GCCAGCTCCA 
CCCCAGCAGG AGGGGCCACC AGAGCAGCAG CCACCACAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268045.1
CDS	64..2385
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ

Target ORF information:

RefSeq Version	XM_005267988.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267988.3

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG ATAAGGAGTA TGATGAATGT 
ACATCAGATG GGAGGGAAGA TGGCAGACTG TGGTGTGCTA CAACCTATGA CTACAAAGCA 
GATGAAAAGT GGGGCTTTTG TGAAACTGAA GAAGAGGCTG CTAAGAGACG GCAGATGCAG 
GAAGCAGAAA TGATGTATCA AACTGGAATG AAAATCCTTA ATGGAAGCAA TAAGAAAAGC 
CAAAAAAGAG AAGCATATCG GTATCTCCAA AAGGCAGCAA GCATGAACCA TACCAAAGCC 
CTGGAGAGAG TGTCATATGC TCTTTTATTT GGTGATTACT TGCCACAGAA TATCCAGGCA 
GCGAGAGAGA TGTTTGAGAA GCTGACTGAG GAAGGCTCTC CCAAGGGACA GACTGCTCTT 
GGCTTTCTGT ATGCCTCTGG ACTTGGTGTT AATTCAAGTC AGGCAAAGGC TCTTGTATAT 
TATACATTTG GAGCTCTTGG GGGCAATCTA ATAGCCCACA TGGTTTTGGG TTACAGATAC 
TGGGCTGGCA TCGGCGTCCT CCAGAGTTGT GAATCTGCCC TGACTCACTA TCGTCTTGTT 
GCCAATCATG TTGCTAGTGA TATCTCGCTA ACAGGAGGCT CAGTAGTACA GAGAATACGG 
CTGCCTGATG AAGTGGAAAA TCCAGGAATG AACAGTGGAA TGCTAGAAGA AGATTTGATT 
CAATATTACC AGTTCCTAGC TGAAAAAGGT GATGTACAAG CACAGGTTGG TCTTGGACAA 
CTGCACCTGC ACGGAGGGCG TGGAGTAGAA CAGAATCATC AGAGAGCATT TGACTACTTC 
AATTTAGCAG CAAATGCTGG CAATTCACAT GCCATGGCCT TTTTGGGAAA GATGTATTCG 
GAAGGAAGTG ACATTGTACC TCAGAGTAAT GAGACAGCTC TCCACTACTT TAAGAAAGCT 
GCTGACATGG GCAACCCAGT TGGACAGAGT GGGCTTGGAA TGGCCTACCT CTATGGGAGA 
GGAGTTCAAG TTAATTATGA TCTAGCCCTT AAGTATTTCC AGAAAGCTGC TGAACAAGGC 
TGGGTGGATG GGCAGCTACA GCTTGGTTCC ATGTACTATA ATGGCATTGG AGTCAAGAGA 
GATTATAAAC AGGCCTTGAA GTATTTTAAT TTAGCTTCTC AGGGAGGCCA TATCTTGGCT 
TTCTATAACC TAGCTCAGAT GCATGCCAGT GGCACCGGCG TGATGCGATC ATGTCACACT 
GCAGTGGAGT TGTTTAAGAA TGTATGTGAA CGAGGCCGTT GGTCTGAAAG GCTTATGACT 
GCCTATAACA GCTATAAAGA TGGCGATTAC AATGCTGCAG TGATCCAGTA CCTCCTCCTG 
GCTGAACAGG GCTATGAAGT GGCACAAAGC AATGCAGCCT TTATTCTTGA TCAGAGAGAA 
GCAAGCATTG TAGGTGAGAA TGAAACTTAT CCCAGAGCTT TGCTACATTG GAACAGGGCC 
GCCTCTCAAG GCTATACTGT GGCTAGAATT AAGCTCGGAG ACTACCATTT CTATGGGTTT 
GGCACCGATG TAGATTATGA AACTGCATTT ATTCATTACC GTCTGGCTTC TGAGCAGCAA 
CACAGTGCAC AAGCTATGTT TAATCTGGGA TATATGCATG AGAAAGGACT GGGCATTAAA 
CAGGATATTC ACCTTGCGAA ACGTTTTTAT GACATGGCAG CTGAAGCCAG CCCAGATGCA 
CAAGTTCCAG TCTTCCTAGC CCTCTGCAAA TTGGGCGTCG TCTATTTCTT GCAGTACATA 
CGGGAAACAA ACATTCGAGA TATGTTCACC CAACTTGATA TGGACCAGCT TTTGGGACCT 
GAGTGGGACC TTTACCTCAT GACCATCATT GCGCTGCTGT TGGGAACAGT CATAGCTTAC 
AGGCAAAGGC AGCACCAAGA CATGCCTGCA CCCAGGCCTC CAGGGCCACG GCCAGCTCCA 
CCCCAGCAGG AGGGGCCACC AGAGCAGCAG CCACCACAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEL1L ( XM_005267989.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268046.1 Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu47856
Clone ID Related Accession (Same CDS sequence)	XM_005267989.4 , XM_005267989.3
Accession Version	XM_005267989.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2316bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005267989.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGATGTA TTCGGAAGGA 
AGTGACATTG TACCTCAGAG TAATGAGACA GCTCTCCACT ACTTTAAGAA AGCTGCTGAC 
ATGGGCAACC CAGTTGGACA GAGTGGGCTT GGAATGGCCT ACCTCTATGG GAGAGGAGTT 
CAAGTTAATT ATGATCTAGC CCTTAAGTAT TTCCAGAAAG CTGCTGAACA AGGCTGGGTG 
GATGGGCAGC TACAGCTTGG TTCCATGTAC TATAATGGCA TTGGAGTCAA GAGAGATTAT 
AAACAGGCCT TGAAGTATTT TAATTTAGCT TCTCAGGGAG GCCATATCTT GGCTTTCTAT 
AACCTAGCTC AGATGCATGC CAGTGGCACC GGCGTGATGC GATCATGTCA CACTGCAGTG 
GAGTTGTTTA AGAATGTATG TGAACGAGGC CGTTGGTCTG AAAGGCTTAT GACTGCCTAT 
AACAGCTATA AAGATGGCGA TTACAATGCT GCAGTGATCC AGTACCTCCT CCTGGCTGAA 
CAGGGCTATG AAGTGGCACA AAGCAATGCA GCCTTTATTC TTGATCAGAG AGAAGCAAGC 
ATTGTAGGTG AGAATGAAAC TTATCCCAGA GCTTTGCTAC ATTGGAACAG GGCCGCCTCT 
CAAGGCTATA CTGTGGCTAG AATTAAGCTC GGAGACTACC ATTTCTATGG GTTTGGCACC 
GATGTAGATT ATGAAACTGC ATTTATTCAT TACCGTCTGG CTTCTGAGCA GCAACACAGT 
GCACAAGCTA TGTTTAATCT GGGATATATG CATGAGAAAG GACTGGGCAT TAAACAGGAT 
ATTCACCTTG CGAAACGTTT TTATGACATG GCAGCTGAAG CCAGCCCAGA TGCACAAGTT 
CCAGTCTTCC TAGCCCTCTG CAAATTGGGC GTCGTCTATT TCTTGCAGTA CATACGGGAA 
ACAAACATTC GAGATATGTT CACCCAACTT GATATGGACC AGCTTTTGGG ACCTGAGTGG 
GACCTTTACC TCATGACCAT CATTGCGCTG CTGTTGGGAA CAGTCATAGC TTACAGGCAA 
AGGCAGCACC AAGACATGCC TGCACCCAGG CCTCCAGGGC CACGGCCAGC TCCACCCCAG 
CAGGAGGGGC CACCAGAGCA GCAGCCACCA CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268046.1
CDS	109..2424
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ

Target ORF information:

RefSeq Version	XM_005267989.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L adaptor subunit of ERAD E3 ubiquitin ligase (SEL1L), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267989.4

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGATGTA TTCGGAAGGA 
AGTGACATTG TACCTCAGAG TAATGAGACA GCTCTCCACT ACTTTAAGAA AGCTGCTGAC 
ATGGGCAACC CAGTTGGACA GAGTGGGCTT GGAATGGCCT ACCTCTATGG GAGAGGAGTT 
CAAGTTAATT ATGATCTAGC CCTTAAGTAT TTCCAGAAAG CTGCTGAACA AGGCTGGGTG 
GATGGGCAGC TACAGCTTGG TTCCATGTAC TATAATGGCA TTGGAGTCAA GAGAGATTAT 
AAACAGGCCT TGAAGTATTT TAATTTAGCT TCTCAGGGAG GCCATATCTT GGCTTTCTAT 
AACCTAGCTC AGATGCATGC CAGTGGCACC GGCGTGATGC GATCATGTCA CACTGCAGTG 
GAGTTGTTTA AGAATGTATG TGAACGAGGC CGTTGGTCTG AAAGGCTTAT GACTGCCTAT 
AACAGCTATA AAGATGGCGA TTACAATGCT GCAGTGATCC AGTACCTCCT CCTGGCTGAA 
CAGGGCTATG AAGTGGCACA AAGCAATGCA GCCTTTATTC TTGATCAGAG AGAAGCAAGC 
ATTGTAGGTG AGAATGAAAC TTATCCCAGA GCTTTGCTAC ATTGGAACAG GGCCGCCTCT 
CAAGGCTATA CTGTGGCTAG AATTAAGCTC GGAGACTACC ATTTCTATGG GTTTGGCACC 
GATGTAGATT ATGAAACTGC ATTTATTCAT TACCGTCTGG CTTCTGAGCA GCAACACAGT 
GCACAAGCTA TGTTTAATCT GGGATATATG CATGAGAAAG GACTGGGCAT TAAACAGGAT 
ATTCACCTTG CGAAACGTTT TTATGACATG GCAGCTGAAG CCAGCCCAGA TGCACAAGTT 
CCAGTCTTCC TAGCCCTCTG CAAATTGGGC GTCGTCTATT TCTTGCAGTA CATACGGGAA 
ACAAACATTC GAGATATGTT CACCCAACTT GATATGGACC AGCTTTTGGG ACCTGAGTGG 
GACCTTTACC TCATGACCAT CATTGCGCTG CTGTTGGGAA CAGTCATAGC TTACAGGCAA 
AGGCAGCACC AAGACATGCC TGCACCCAGG CCTCCAGGGC CACGGCCAGC TCCACCCCAG 
CAGGAGGGGC CACCAGAGCA GCAGCCACCA CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEL1L ( XM_005267989.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268046.1 Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu47856
Clone ID Related Accession (Same CDS sequence)	XM_005267989.4 , XM_005267989.3
Accession Version	XM_005267989.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2316bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	protein sel-1 homolog 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267989.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGATGTA TTCGGAAGGA 
AGTGACATTG TACCTCAGAG TAATGAGACA GCTCTCCACT ACTTTAAGAA AGCTGCTGAC 
ATGGGCAACC CAGTTGGACA GAGTGGGCTT GGAATGGCCT ACCTCTATGG GAGAGGAGTT 
CAAGTTAATT ATGATCTAGC CCTTAAGTAT TTCCAGAAAG CTGCTGAACA AGGCTGGGTG 
GATGGGCAGC TACAGCTTGG TTCCATGTAC TATAATGGCA TTGGAGTCAA GAGAGATTAT 
AAACAGGCCT TGAAGTATTT TAATTTAGCT TCTCAGGGAG GCCATATCTT GGCTTTCTAT 
AACCTAGCTC AGATGCATGC CAGTGGCACC GGCGTGATGC GATCATGTCA CACTGCAGTG 
GAGTTGTTTA AGAATGTATG TGAACGAGGC CGTTGGTCTG AAAGGCTTAT GACTGCCTAT 
AACAGCTATA AAGATGGCGA TTACAATGCT GCAGTGATCC AGTACCTCCT CCTGGCTGAA 
CAGGGCTATG AAGTGGCACA AAGCAATGCA GCCTTTATTC TTGATCAGAG AGAAGCAAGC 
ATTGTAGGTG AGAATGAAAC TTATCCCAGA GCTTTGCTAC ATTGGAACAG GGCCGCCTCT 
CAAGGCTATA CTGTGGCTAG AATTAAGCTC GGAGACTACC ATTTCTATGG GTTTGGCACC 
GATGTAGATT ATGAAACTGC ATTTATTCAT TACCGTCTGG CTTCTGAGCA GCAACACAGT 
GCACAAGCTA TGTTTAATCT GGGATATATG CATGAGAAAG GACTGGGCAT TAAACAGGAT 
ATTCACCTTG CGAAACGTTT TTATGACATG GCAGCTGAAG CCAGCCCAGA TGCACAAGTT 
CCAGTCTTCC TAGCCCTCTG CAAATTGGGC GTCGTCTATT TCTTGCAGTA CATACGGGAA 
ACAAACATTC GAGATATGTT CACCCAACTT GATATGGACC AGCTTTTGGG ACCTGAGTGG 
GACCTTTACC TCATGACCAT CATTGCGCTG CTGTTGGGAA CAGTCATAGC TTACAGGCAA 
AGGCAGCACC AAGACATGCC TGCACCCAGG CCTCCAGGGC CACGGCCAGC TCCACCCCAG 
CAGGAGGGGC CACCAGAGCA GCAGCCACCA CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268046.1
CDS	121..2436
Translation	MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ

Target ORF information:

RefSeq Version	XM_005267989.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SEL1L ERAD E3 ligase adaptor subunit (SEL1L), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267989.3

ORF Insert Sequence:

ATGCGGGTCC GGATAGGGCT GACGCTGCTG CTGTGTGCGG TGCTGCTGAG CTTGGCCTCG 
GCGTCCTCGG ATGAAGAAGG CAGCCAGGAT GAATCCTTAG ATTCCAAGAC TACTTTGACA 
TCAGATGAGT CAGTAAAGGA CCATACTACT GCAGGCAGAG TAGTTGCTGG TCAAATATTT 
CTTGATTCAG AAGAATCTGA ATTAGAATCC TCTATTCAAG AAGAGGAAGA CAGCCTCAAG 
AGCCAAGAGG GGGAAAGTGT CACAGAAGAT ATCAGCTTTC TAGAGTCTCC AAATCCAGAA 
AACAAGGACT ATGAAGAGCC AAAGAAAGTA CGGAAACCAG CTTTGACCGC CATTGAAGGC 
ACAGCACATG GGGAGCCCTG CCACTTCCCT TTTCTTTTCC TAGATAAGGA GTATGATGAA 
TGTACATCAG ATGGGAGGGA AGATGGCAGA CTGTGGTGTG CTACAACCTA TGACTACAAA 
GCAGATGAAA AGTGGGGCTT TTGTGAAACT GAAGAAGAGG CTGCTAAGAG ACGGCAGATG 
CAGGAAGCAG AAATGATGTA TCAAACTGGA ATGAAAATCC TTAATGGAAG CAATAAGAAA 
AGCCAAAAAA GAGAAGCATA TCGGTATCTC CAAAAGGCAG CAAGCATGAA CCATACCAAA 
GCCCTGGAGA GAGTGTCATA TGCTCTTTTA TTTGGTGATT ACTTGCCACA GAATATCCAG 
GCAGCGAGAG AGATGTTTGA GAAGCTGACT GAGGAAGGCT CTCCCAAGGG ACAGACTGCT 
CTTGGCTTTC TGTATGCCTC TGGACTTGGT GTTAATTCAA GTCAGGCAAA GGCTCTTGTA 
TATTATACAT TTGGAGCTCT TGGGGGCAAT CTAATAGCCC ACATGGTTTT GGGTTACAGA 
TACTGGGCTG GCATCGGCGT CCTCCAGAGT TGTGAATCTG CCCTGACTCA CTATCGTCTT 
GTTGCCAATC ATGTTGCTAG TGATATCTCG CTAACAGGAG GCTCAGTAGT ACAGAGAATA 
CGGCTGCCTG ATGAAGTGGA AAATCCAGGA ATGAACAGTG GAATGCTAGA AGAAGATTTG 
ATTCAATATT ACCAGTTCCT AGCTGAAAAA GGTGATGTAC AAGCACAGGT TGGTCTTGGA 
CAACTGCACC TGCACGGAGG GCGTGGAGTA GAACAGAATC ATCAGATGTA TTCGGAAGGA 
AGTGACATTG TACCTCAGAG TAATGAGACA GCTCTCCACT ACTTTAAGAA AGCTGCTGAC 
ATGGGCAACC CAGTTGGACA GAGTGGGCTT GGAATGGCCT ACCTCTATGG GAGAGGAGTT 
CAAGTTAATT ATGATCTAGC CCTTAAGTAT TTCCAGAAAG CTGCTGAACA AGGCTGGGTG 
GATGGGCAGC TACAGCTTGG TTCCATGTAC TATAATGGCA TTGGAGTCAA GAGAGATTAT 
AAACAGGCCT TGAAGTATTT TAATTTAGCT TCTCAGGGAG GCCATATCTT GGCTTTCTAT 
AACCTAGCTC AGATGCATGC CAGTGGCACC GGCGTGATGC GATCATGTCA CACTGCAGTG 
GAGTTGTTTA AGAATGTATG TGAACGAGGC CGTTGGTCTG AAAGGCTTAT GACTGCCTAT 
AACAGCTATA AAGATGGCGA TTACAATGCT GCAGTGATCC AGTACCTCCT CCTGGCTGAA 
CAGGGCTATG AAGTGGCACA AAGCAATGCA GCCTTTATTC TTGATCAGAG AGAAGCAAGC 
ATTGTAGGTG AGAATGAAAC TTATCCCAGA GCTTTGCTAC ATTGGAACAG GGCCGCCTCT 
CAAGGCTATA CTGTGGCTAG AATTAAGCTC GGAGACTACC ATTTCTATGG GTTTGGCACC 
GATGTAGATT ATGAAACTGC ATTTATTCAT TACCGTCTGG CTTCTGAGCA GCAACACAGT 
GCACAAGCTA TGTTTAATCT GGGATATATG CATGAGAAAG GACTGGGCAT TAAACAGGAT 
ATTCACCTTG CGAAACGTTT TTATGACATG GCAGCTGAAG CCAGCCCAGA TGCACAAGTT 
CCAGTCTTCC TAGCCCTCTG CAAATTGGGC GTCGTCTATT TCTTGCAGTA CATACGGGAA 
ACAAACATTC GAGATATGTT CACCCAACTT GATATGGACC AGCTTTTGGG ACCTGAGTGG 
GACCTTTACC TCATGACCAT CATTGCGCTG CTGTTGGGAA CAGTCATAGC TTACAGGCAA 
AGGCAGCACC AAGACATGCC TGCACCCAGG CCTCCAGGGC CACGGCCAGC TCCACCCCAG 
CAGGAGGGGC CACCAGAGCA GCAGCCACCA CAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2.
Biochemical and biophysical research communications477(4)841-846(2016 09)
Choi SI,Lee E,Jeong JB,Akuzum B,Maeng YS,Kim TI,Kim EK

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SEL1L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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