GPATCH3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPATCH3
Entrez Gene ID	63906
Full Name	G-patch domain containing 3
Synonyms	GPATC3
General protein information	Preferred Names G-patch domain containing 3 Names G patch domain-containing protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.11
Disorder MIM:	617486

mRNA and Protein(s)

mRNA	Protein	Name
NM_022078.3	NP_071361.2	G patch domain-containing protein 3
NM_022078.2	NP_071361.2	G patch domain-containing protein 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	GPATCH3	XP_544476.2
Caenorhabditis elegans (roundworm)	K07B1.7	NP_505420.1
Xenopus tropicalis (tropical clawed frog)	gpatch3	NP_001120471.1
Bos taurus (cattle)	GPATCH3	NP_001092442.1
Mus musculus (house mouse)	Gpatch3	NP_766464.1
Rattus norvegicus (Norway rat)	Gpatch3	XP_342934.3
Gallus gallus (chicken)	GPATCH3	NP_001185469.1
Danio rerio (zebrafish)	gpatch3	NP_001074099.1
Homo sapiens (human)	GPATCH3	NP_071361.2
Pan troglodytes (chimpanzee)	GPATCH3	XP_513237.2
	GPATCH3	XP_001110411.1

Gene Ontology
Bibliography

Related articles in PubMed

GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome.
Nie Y, Ran Y, Zhang HY, Huang ZF, Pan ZY, Wang SY, Wang YY
PLoS pathogens13(4)e1006328(2017 Apr)

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development.
Ferre-Fern?ndez JJ, Aroca-Aguilar JD, Medina-Trillo C, Bonet-Fern?ndez JM, M?ndez-Hern?ndez CD, Morales-Fern?ndez L, Corton M, Caba?ero-Valera MJ, Gut M, Tonda R, Ayuso C, Coca-Prados M, Garc?a-Feijoo J, Escribano J
Scientific reports746175(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GPATCH3 interacts with VISA and disrupts the assembly of virus-induced VISA signalosome therefore acts as a negative regulator of RLR-mediated innate antiviral immune responses.
Title: GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome.

The following GPATCH3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPATCH3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03792	NM_022078.3 Latest version!	Homo sapiens G-patch domain containing 3 (GPATCH3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu03792	NM_022078.2	Homo sapiens G-patch domain containing 3 (GPATCH3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPATCH3 ( NM_022078.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071361.2 Homo sapiens G-patch domain containing 3 (GPATCH3), mRNA.

Price & Availability↑

CloneID	OHu03792
Clone ID Related Accession (Same CDS sequence)	NM_022078.3 , NM_022078.2
Accession Version	NM_022078.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	G patch domain-containing protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA513389.1, BC007767.2 and AW137695.1. On Nov 22, 2018 this sequence version replaced NM_022078.2. ##Evidence-Data-START## Transcript exon combination :: CR936767.1, AK022517.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000361720.10/ ENSP00000354645.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGTGC CCGGCGAGGC GGAGGAGGAG GCGACAGTTT ACCTGGTAGT GAGCGGTATC 
CCCTCCGTGT TGCGCTCGGC CCATTTACGG AGCTATTTTA GCCAGTTCCG AGAAGAGCGC 
GGCGGTGGCT TCCTCTGTTT CCACTACCGG CATCGGCCTG AGCGGGCCCC TCCGCAGGCC 
GCTCCTAACT CTGCCCTAAT TCCTACCGAC CCAGCCGCTG AGGGCCAGCT TCTCTCTCAG 
ACTTCGGCCA CCGATGTCCG GCCTCTCTCC ACTCGAGACT CTACTCCAAT CCAGACCCGC 
ACCTGCTGCT GCGTCATCTC GGTAAGGGGG TTGGCTCAAG CTCAGAGGCT TATTCGCATG 
TACTCGGGCC GCCGGTGGCT GGATTCTCAC GGGACTTGGC TACCGGGTCG CTGTCTCATC 
CGCAGACTTC GGCTACCTAC GGAGGCATCA GGTCTGGGCT CCTTTCCCTT CAAGACCCGG 
AAGGAACTGC AGAGTTGGAA GGCAGAGAAT GAAGCCTTCA CCCTGGCTGA CCTGAAGCAA 
CTGCCGGAGC TGAACCCACC AGTGCTGATG CCCAGAGGGA ATGTGGGGAC TCCCCTGCGG 
GTCTTTTTGG AGTTGATCCG GGCCTGCCGC CTACCCCCTC GGATCATCAC CCAGCTGCAG 
CTCCAGTTCC CCAAGACAGG TTCCTCCCGG CGCTACGGCA ATGTGCCTTT TGAGTATGAG 
GACTCAGAGA CTGTGGAGCA GGAAGAGCTT GTGTATACAG CAGAGGGTGA AGAAATACCC 
CAAGGAACCT ACCTGGCAGA TATACCAGCC AGCCCCTGTG GAGAGCCTGA GGAAGAAGTG 
GGGAAGGAAG AGGAAGAAGA GTCTCACTCA GATGAGGACG ATGACCGGGG TGAGGAATGG 
GAACGGCATG AAGCGCTGCA TGAGGACGTG ACCGGGCAGG AGCGGACCAC TGAGCAGCTC 
TTTGAGGAGG AGATTGAGCT CAAGTGGGAG AAGGGTGGCT CTGGCCTGGT GTTTTATACT 
GATGCCCAGT TCTGGCAGGA GGAAGAAGGA GATTTTGATG AACAGACAGC CGATGACTGG 
GATGTGGACA TGAGTGTGTA CTATGACAGA GATGGTGGAG ACAAGGATGC CCGAGACTCT 
GTCCAAATGC GTCTGGAACA GAGACTCCGA GATGGACAGG AAGATGGCTC TGTGATCGAA 
CGCCAGGTGG GCACCTTTGA GCGCCACACC AAGGGCATTG GGCGGAAGGT GATGGAGCGG 
CAGGGCTGGG CTGAGGGCCA GGGCCTGGGC TGCAGGTGCT CAGGGGTGCC TGAGGCCCTG 
GATAGTGATG GCCAACACCC CAGATGCAAG CGTGGATTGG GGTACCATGG AGAGAAGCTA 
CAGCCATTTG GGCAACTGAA GAGGCCCCGT AGAAATGGCT TGGGGCTCAT CTCCACCATC 
TATGATGAGC CTCTACCCCA AGACCAGACG GAGTCACTGC TCCGCCGCCA GCCACCCACC 
AGCATGAAGT TTCGGACAGA CATGGCCTTT GTGAGGGGTT CCAGTTGTGC TTCAGACAGC 
CCCTCATTGC CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071361.2
CDS	26..1603
Translation	MAVPGEAEEEATVYLVVSGIPSVLRSAHLRSYFSQFREERGGGFLCFHYRHRPERAPPQAAPNSALIPTDPAAEGQLLSQTSATDVRPLSTRDSTPIQTRTCCCVISVRGLAQAQRLIRMYSGRRWLDSHGTWLPGRCLIRRLRLPTEASGLGSFPFKTRKELQSWKAENEAFTLADLKQLPELNPPVLMPRGNVGTPLRVFLELIRACRLPPRIITQLQLQFPKTGSSRRYGNVPFEYEDSETVEQEELVYTAEGEEIPQGTYLADIPASPCGEPEEEVGKEEEEESHSDEDDDRGEEWERHEALHEDVTGQERTTEQLFEEEIELKWEKGGSGLVFYTDAQFWQEEEGDFDEQTADDWDVDMSVYYDRDGGDKDARDSVQMRLEQRLRDGQEDGSVIERQVGTFERHTKGIGRKVMERQGWAEGQGLGCRCSGVPEALDSDGQHPRCKRGLGYHGEKLQPFGQLKRPRRNGLGLISTIYDEPLPQDQTESLLRRQPPTSMKFRTDMAFVRGSSCASDSPSLPD

Target ORF information:

RefSeq Version	NM_022078.3
Organism	Homo sapiens(human)
Definition	Homo sapiens G-patch domain containing 3 (GPATCH3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022078.3

ORF Insert Sequence:

ATGGCGGTGC CCGGCGAGGC GGAGGAGGAG GCGACAGTTT ACCTGGTAGT GAGCGGTATC 
CCCTCCGTGT TGCGCTCGGC CCATTTACGG AGCTATTTTA GCCAGTTCCG AGAAGAGCGC 
GGCGGTGGCT TCCTCTGTTT CCACTACCGG CATCGGCCTG AGCGGGCCCC TCCGCAGGCC 
GCTCCTAACT CTGCCCTAAT TCCTACCGAC CCAGCCGCTG AGGGCCAGCT TCTCTCTCAG 
ACTTCGGCCA CCGATGTCCG GCCTCTCTCC ACTCGAGACT CTACTCCAAT CCAGACCCGC 
ACCTGCTGCT GCGTCATCTC GGTAAGGGGG TTGGCTCAAG CTCAGAGGCT TATTCGCATG 
TACTCGGGCC GCCGGTGGCT GGATTCTCAC GGGACTTGGC TACCGGGTCG CTGTCTCATC 
CGCAGACTTC GGCTACCTAC GGAGGCATCA GGTCTGGGCT CCTTTCCCTT CAAGACCCGG 
AAGGAACTGC AGAGTTGGAA GGCAGAGAAT GAAGCCTTCA CCCTGGCTGA CCTGAAGCAA 
CTGCCGGAGC TGAACCCACC AGTGCTGATG CCCAGAGGGA ATGTGGGGAC TCCCCTGCGG 
GTCTTTTTGG AGTTGATCCG GGCCTGCCGC CTACCCCCTC GGATCATCAC CCAGCTGCAG 
CTCCAGTTCC CCAAGACAGG TTCCTCCCGG CGCTACGGCA ATGTGCCTTT TGAGTATGAG 
GACTCAGAGA CTGTGGAGCA GGAAGAGCTT GTGTATACAG CAGAGGGTGA AGAAATACCC 
CAAGGAACCT ACCTGGCAGA TATACCAGCC AGCCCCTGTG GAGAGCCTGA GGAAGAAGTG 
GGGAAGGAAG AGGAAGAAGA GTCTCACTCA GATGAGGACG ATGACCGGGG TGAGGAATGG 
GAACGGCATG AAGCGCTGCA TGAGGACGTG ACCGGGCAGG AGCGGACCAC TGAGCAGCTC 
TTTGAGGAGG AGATTGAGCT CAAGTGGGAG AAGGGTGGCT CTGGCCTGGT GTTTTATACT 
GATGCCCAGT TCTGGCAGGA GGAAGAAGGA GATTTTGATG AACAGACAGC CGATGACTGG 
GATGTGGACA TGAGTGTGTA CTATGACAGA GATGGTGGAG ACAAGGATGC CCGAGACTCT 
GTCCAAATGC GTCTGGAACA GAGACTCCGA GATGGACAGG AAGATGGCTC TGTGATCGAA 
CGCCAGGTGG GCACCTTTGA GCGCCACACC AAGGGCATTG GGCGGAAGGT GATGGAGCGG 
CAGGGCTGGG CTGAGGGCCA GGGCCTGGGC TGCAGGTGCT CAGGGGTGCC TGAGGCCCTG 
GATAGTGATG GCCAACACCC CAGATGCAAG CGTGGATTGG GGTACCATGG AGAGAAGCTA 
CAGCCATTTG GGCAACTGAA GAGGCCCCGT AGAAATGGCT TGGGGCTCAT CTCCACCATC 
TATGATGAGC CTCTACCCCA AGACCAGACG GAGTCACTGC TCCGCCGCCA GCCACCCACC 
AGCATGAAGT TTCGGACAGA CATGGCCTTT GTGAGGGGTT CCAGTTGTGC TTCAGACAGC 
CCCTCATTGC CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPATCH3 ( NM_022078.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_071361.2 Homo sapiens G-patch domain containing 3 (GPATCH3), mRNA.

Price & Availability↑

CloneID	OHu03792
Clone ID Related Accession (Same CDS sequence)	NM_022078.3 , NM_022078.2
Accession Version	NM_022078.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1578bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	G patch domain-containing protein 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA513389.1, BC007767.2 and AW137695.1. On Sep 19, 2008 this sequence version replaced NM_022078.1. ##Evidence-Data-START## Transcript exon combination :: CR936767.1, AK022517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144, SAMN03267755 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGTGC CCGGCGAGGC GGAGGAGGAG GCGACAGTTT ACCTGGTAGT GAGCGGTATC 
CCCTCCGTGT TGCGCTCGGC CCATTTACGG AGCTATTTTA GCCAGTTCCG AGAAGAGCGC 
GGCGGTGGCT TCCTCTGTTT CCACTACCGG CATCGGCCTG AGCGGGCCCC TCCGCAGGCC 
GCTCCTAACT CTGCCCTAAT TCCTACCGAC CCAGCCGCTG AGGGCCAGCT TCTCTCTCAG 
ACTTCGGCCA CCGATGTCCG GCCTCTCTCC ACTCGAGACT CTACTCCAAT CCAGACCCGC 
ACCTGCTGCT GCGTCATCTC GGTAAGGGGG TTGGCTCAAG CTCAGAGGCT TATTCGCATG 
TACTCGGGCC GCCGGTGGCT GGATTCTCAC GGGACTTGGC TACCGGGTCG CTGTCTCATC 
CGCAGACTTC GGCTACCTAC GGAGGCATCA GGTCTGGGCT CCTTTCCCTT CAAGACCCGG 
AAGGAACTGC AGAGTTGGAA GGCAGAGAAT GAAGCCTTCA CCCTGGCTGA CCTGAAGCAA 
CTGCCGGAGC TGAACCCACC AGTGCTGATG CCCAGAGGGA ATGTGGGGAC TCCCCTGCGG 
GTCTTTTTGG AGTTGATCCG GGCCTGCCGC CTACCCCCTC GGATCATCAC CCAGCTGCAG 
CTCCAGTTCC CCAAGACAGG TTCCTCCCGG CGCTACGGCA ATGTGCCTTT TGAGTATGAG 
GACTCAGAGA CTGTGGAGCA GGAAGAGCTT GTGTATACAG CAGAGGGTGA AGAAATACCC 
CAAGGAACCT ACCTGGCAGA TATACCAGCC AGCCCCTGTG GAGAGCCTGA GGAAGAAGTG 
GGGAAGGAAG AGGAAGAAGA GTCTCACTCA GATGAGGACG ATGACCGGGG TGAGGAATGG 
GAACGGCATG AAGCGCTGCA TGAGGACGTG ACCGGGCAGG AGCGGACCAC TGAGCAGCTC 
TTTGAGGAGG AGATTGAGCT CAAGTGGGAG AAGGGTGGCT CTGGCCTGGT GTTTTATACT 
GATGCCCAGT TCTGGCAGGA GGAAGAAGGA GATTTTGATG AACAGACAGC CGATGACTGG 
GATGTGGACA TGAGTGTGTA CTATGACAGA GATGGTGGAG ACAAGGATGC CCGAGACTCT 
GTCCAAATGC GTCTGGAACA GAGACTCCGA GATGGACAGG AAGATGGCTC TGTGATCGAA 
CGCCAGGTGG GCACCTTTGA GCGCCACACC AAGGGCATTG GGCGGAAGGT GATGGAGCGG 
CAGGGCTGGG CTGAGGGCCA GGGCCTGGGC TGCAGGTGCT CAGGGGTGCC TGAGGCCCTG 
GATAGTGATG GCCAACACCC CAGATGCAAG CGTGGATTGG GGTACCATGG AGAGAAGCTA 
CAGCCATTTG GGCAACTGAA GAGGCCCCGT AGAAATGGCT TGGGGCTCAT CTCCACCATC 
TATGATGAGC CTCTACCCCA AGACCAGACG GAGTCACTGC TCCGCCGCCA GCCACCCACC 
AGCATGAAGT TTCGGACAGA CATGGCCTTT GTGAGGGGTT CCAGTTGTGC TTCAGACAGC 
CCCTCATTGC CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071361.2
CDS	30..1607
Translation	MAVPGEAEEEATVYLVVSGIPSVLRSAHLRSYFSQFREERGGGFLCFHYRHRPERAPPQAAPNSALIPTDPAAEGQLLSQTSATDVRPLSTRDSTPIQTRTCCCVISVRGLAQAQRLIRMYSGRRWLDSHGTWLPGRCLIRRLRLPTEASGLGSFPFKTRKELQSWKAENEAFTLADLKQLPELNPPVLMPRGNVGTPLRVFLELIRACRLPPRIITQLQLQFPKTGSSRRYGNVPFEYEDSETVEQEELVYTAEGEEIPQGTYLADIPASPCGEPEEEVGKEEEEESHSDEDDDRGEEWERHEALHEDVTGQERTTEQLFEEEIELKWEKGGSGLVFYTDAQFWQEEEGDFDEQTADDWDVDMSVYYDRDGGDKDARDSVQMRLEQRLRDGQEDGSVIERQVGTFERHTKGIGRKVMERQGWAEGQGLGCRCSGVPEALDSDGQHPRCKRGLGYHGEKLQPFGQLKRPRRNGLGLISTIYDEPLPQDQTESLLRRQPPTSMKFRTDMAFVRGSSCASDSPSLPD

Target ORF information:

RefSeq Version	NM_022078.2
Organism	Homo sapiens(human)
Definition	Homo sapiens G-patch domain containing 3 (GPATCH3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022078.2

ORF Insert Sequence:

ATGGCGGTGC CCGGCGAGGC GGAGGAGGAG GCGACAGTTT ACCTGGTAGT GAGCGGTATC 
CCCTCCGTGT TGCGCTCGGC CCATTTACGG AGCTATTTTA GCCAGTTCCG AGAAGAGCGC 
GGCGGTGGCT TCCTCTGTTT CCACTACCGG CATCGGCCTG AGCGGGCCCC TCCGCAGGCC 
GCTCCTAACT CTGCCCTAAT TCCTACCGAC CCAGCCGCTG AGGGCCAGCT TCTCTCTCAG 
ACTTCGGCCA CCGATGTCCG GCCTCTCTCC ACTCGAGACT CTACTCCAAT CCAGACCCGC 
ACCTGCTGCT GCGTCATCTC GGTAAGGGGG TTGGCTCAAG CTCAGAGGCT TATTCGCATG 
TACTCGGGCC GCCGGTGGCT GGATTCTCAC GGGACTTGGC TACCGGGTCG CTGTCTCATC 
CGCAGACTTC GGCTACCTAC GGAGGCATCA GGTCTGGGCT CCTTTCCCTT CAAGACCCGG 
AAGGAACTGC AGAGTTGGAA GGCAGAGAAT GAAGCCTTCA CCCTGGCTGA CCTGAAGCAA 
CTGCCGGAGC TGAACCCACC AGTGCTGATG CCCAGAGGGA ATGTGGGGAC TCCCCTGCGG 
GTCTTTTTGG AGTTGATCCG GGCCTGCCGC CTACCCCCTC GGATCATCAC CCAGCTGCAG 
CTCCAGTTCC CCAAGACAGG TTCCTCCCGG CGCTACGGCA ATGTGCCTTT TGAGTATGAG 
GACTCAGAGA CTGTGGAGCA GGAAGAGCTT GTGTATACAG CAGAGGGTGA AGAAATACCC 
CAAGGAACCT ACCTGGCAGA TATACCAGCC AGCCCCTGTG GAGAGCCTGA GGAAGAAGTG 
GGGAAGGAAG AGGAAGAAGA GTCTCACTCA GATGAGGACG ATGACCGGGG TGAGGAATGG 
GAACGGCATG AAGCGCTGCA TGAGGACGTG ACCGGGCAGG AGCGGACCAC TGAGCAGCTC 
TTTGAGGAGG AGATTGAGCT CAAGTGGGAG AAGGGTGGCT CTGGCCTGGT GTTTTATACT 
GATGCCCAGT TCTGGCAGGA GGAAGAAGGA GATTTTGATG AACAGACAGC CGATGACTGG 
GATGTGGACA TGAGTGTGTA CTATGACAGA GATGGTGGAG ACAAGGATGC CCGAGACTCT 
GTCCAAATGC GTCTGGAACA GAGACTCCGA GATGGACAGG AAGATGGCTC TGTGATCGAA 
CGCCAGGTGG GCACCTTTGA GCGCCACACC AAGGGCATTG GGCGGAAGGT GATGGAGCGG 
CAGGGCTGGG CTGAGGGCCA GGGCCTGGGC TGCAGGTGCT CAGGGGTGCC TGAGGCCCTG 
GATAGTGATG GCCAACACCC CAGATGCAAG CGTGGATTGG GGTACCATGG AGAGAAGCTA 
CAGCCATTTG GGCAACTGAA GAGGCCCCGT AGAAATGGCT TGGGGCTCAT CTCCACCATC 
TATGATGAGC CTCTACCCCA AGACCAGACG GAGTCACTGC TCCGCCGCCA GCCACCCACC 
AGCATGAAGT TTCGGACAGA CATGGCCTTT GTGAGGGGTT CCAGTTGTGC TTCAGACAGC 
CCCTCATTGC CTGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome.
PLoS pathogens13(4)e1006328(2017 Apr)
Nie Y,Ran Y,Zhang HY,Huang ZF,Pan ZY,Wang SY,Wang YY

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development.
Scientific reports746175(2017 Apr)
Ferre-Fern?ndez JJ,Aroca-Aguilar JD,Medina-Trillo C,Bonet-Fern?ndez JM,M?ndez-Hern?ndez CD,Morales-Fern?ndez L,Corton M,Caba?ero-Valera MJ,Gut M,Tonda R,Ayuso C,Coca-Prados M,Garc?a-Feijoo J,Escribano J

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GPATCH3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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