CCL24 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL24
Entrez Gene ID	6369
Full Name	C-C motif chemokine ligand 24
Synonyms	Ckb-6,MPIF-2,MPIF2,SCYA24
General protein information	Preferred Names C-C motif chemokine ligand 24 Names C-C motif chemokine 24 CK-beta-6 chemokine (C-C motif) ligand 24 eosinophil chemotactic protein 2 eotaxin-2 myeloid progenitor inhibitory factor 2 small inducible cytokine subfamily A (Cys-Cys), member 24 small-inducible cytokine A24
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q11.23
Summary	This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008].
Disorder MIM:	602495

mRNA and Protein(s)

mRNA	Protein	Name
XM_011516460.2	XP_011514762.1	C-C motif chemokine 24 isoform X1
NM_001371193.1	NP_001358122.1	C-C motif chemokine 24 precursor
NM_002991.3	NP_002982.2	C-C motif chemokine 24 precursor
XM_011516459.2	XP_011514761.1	C-C motif chemokine 24 isoform X1
NM_002991.2	NP_002982.2	C-C motif chemokine 24 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CCL24	XP_001155246.1
Rattus norvegicus (Norway rat)	Ccl24	NP_001013063.1
Homo sapiens (human)	CCL24	NP_002982.2
	CCL24	XP_001109757.1
Canis lupus familiaris (dog)	CCL24	NP_001003967.1
Bos taurus (cattle)	CCL24	NP_001040061.1
Mus musculus (house mouse)	Ccl24	NP_062523.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of Fluticasone Furoate Nasal Spray on Parameters of Eosinophilic Inflammation in Patients With Nasal Polyposis and Perennial Allergic Rhinitis.
?padijer Mirkovi? C, Peri? A, Vukomanovi? ?ur?evi? B, Vojvodi? D
The Annals of otology, rhinology, and laryngology126(8)573-580(2017 Aug)

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, D?ring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C
Science translational medicine9(384)(2017 Apr)

CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis.
Jin L, Liu WR, Tian MX, Jiang XF, Wang H, Zhou PY, Ding ZB, Peng YF, Dai Z, Qiu SJ, Zhou J, Fan J, Shi YH
Oncotarget8(3)5135-5148(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mean eotaxin 2 concentrations in nasal fluid in patients with perennial allergic rhinitis and nonallergic and allergic chronic rhinosinusitis with nasal polyps patients were significantly higher in comparison to control subjects.
Title: Effects of Fluticasone Furoate Nasal Spray on Parameters of Eosinophilic Inflammation in Patients With Nasal Polyposis and Perennial Allergic Rhinitis.

Review: eotaxins (CCL11, CCL24, and CCL26) play key role(s) during symptomatic inflammatory responses raised in response to allergic crisis of allergic asthma and atopic dermatitis
Title: An Overlook to the Characteristics and Roles Played by Eotaxin Network in the Pathophysiology of Food Allergies: Allergic Asthma and Atopic Dermatitis.

HMGB1 did not elicit chemotaxis of human eosinophils alone and had no effect in combination with the eosinophil chemotactic agent, eotaxin-2 (CCL24).
Title: Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24).

these data suggest that CCL26 and CCL24 are likely involved in the pathogenesis of chronic nasal hypereosinophilia, with a complex cooperation and different involvement of the various members of eotaxin family.
Title: Nasal fluid release of eotaxin-3 and eotaxin-2 in persistent sinonasal eosinophilic inflammation.

CCL11, CCL24, and CCL26 are increased in TB patients; hence, it seems that TB suppresses Th1 and the classic function of macrophages subsequently by inducing the chemokines' expression
Title: All eotaxins CCL11, CCL24 and CCL26 are increased but to various extents in pulmonary tuberculosis patients.

The following CCL24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15238	NM_002991.3 Latest version!	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu15238	NM_001371193.1 Latest version!	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu15238	XM_011516460.2 Latest version!	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu15238	XM_011516459.2 Latest version!	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu15238	NM_002991.2	Homo sapiens C-C motif chemokine ligand 24 (CCL24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL24 ( NM_002991.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002982.2 Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15238
Clone ID Related Accession (Same CDS sequence)	XM_011516460.2 , NM_001371193.1 , NM_002991.3 , XM_011516459.2 , NM_002991.2
Accession Version	NM_002991.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	C-C motif chemokine 24 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005102.1. On Jul 1, 2019 this sequence version replaced NM_002991.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138524.1242478.1, ERR279848.10084.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002982.2
CDS	92..451
Translation	MAGLMTIVTSLLFLGVCAHHIIPTGSVVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

Target ORF information:

RefSeq Version	NM_002991.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002991.3

ORF Insert Sequence:

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL24 ( NM_001371193.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001358122.1 Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15238
Clone ID Related Accession (Same CDS sequence)	XM_011516460.2 , NM_001371193.1 , NM_002991.3 , XM_011516459.2 , NM_002991.2
Accession Version	NM_001371193.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-30
Organism	Homo sapiens(human)
Product	C-C motif chemokine 24 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005102.1 and AK312216.1. On Jul 1, 2019 this sequence version replaced XM_011516459.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DB010139.1, AK312216.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001358122.1
CDS	111..470
Translation	MAGLMTIVTSLLFLGVCAHHIIPTGSVVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

Target ORF information:

RefSeq Version	NM_001371193.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001371193.1

ORF Insert Sequence:

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL24 ( NM_002991.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002982.2 Homo sapiens C-C motif chemokine ligand 24 (CCL24), mRNA.

Price & Availability↑

CloneID	OHu15238
Clone ID Related Accession (Same CDS sequence)	XM_011516460.2 , NM_001371193.1 , NM_002991.3 , XM_011516459.2 , NM_002991.2
Accession Version	NM_002991.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	C-C motif chemokine 24 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U85768.1. On Aug 9, 2002 this sequence version replaced NM_002991.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC069072.1, U85768.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146236, SAMEA2159764 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002982.2
CDS	1..360
Translation	MAGLMTIVTSLLFLGVCAHHIIPTGSVVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

Target ORF information:

RefSeq Version	NM_002991.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 24 (CCL24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002991.2

ORF Insert Sequence:

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL24 ( XM_011516460.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514762.1 Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu15238
Clone ID Related Accession (Same CDS sequence)	XM_011516460.2 , NM_001371193.1 , NM_002991.3 , XM_011516459.2 , NM_002991.2
Accession Version	XM_011516460.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-C motif chemokine 24 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516460.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514762.1
CDS	268..627
Translation	MAGLMTIVTSLLFLGVCAHHIIPTGSVVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

Target ORF information:

RefSeq Version	XM_011516460.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516460.2

ORF Insert Sequence:

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL24 ( XM_011516459.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514761.1 Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu15238
Clone ID Related Accession (Same CDS sequence)	XM_011516460.2 , NM_001371193.1 , NM_002991.3 , XM_011516459.2 , NM_002991.2
Accession Version	XM_011516459.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 360bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	C-C motif chemokine 24 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516459.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514761.1
CDS	95..454
Translation	MAGLMTIVTSLLFLGVCAHHIIPTGSVVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKAGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

Target ORF information:

RefSeq Version	XM_011516459.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 24 (CCL24), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516459.2

ORF Insert Sequence:

ATGGCAGGCC TGATGACCAT AGTAACCAGC CTTCTGTTCC TTGGTGTCTG TGCCCACCAC 
ATCATCCCTA CGGGCTCTGT GGTCATCCCC TCTCCCTGCT GCATGTTCTT TGTTTCCAAG 
AGAATTCCTG AGAACCGAGT GGTCAGCTAC CAGCTGTCCA GCAGGAGCAC ATGCCTCAAG 
GCAGGAGTGA TCTTCACCAC CAAGAAGGGC CAGCAGTTCT GTGGCGACCC CAAGCAGGAG 
TGGGTCCAGA GGTACATGAA GAACCTGGAC GCCAAGCAGA AGAAGGCTTC CCCTAGGGCC 
AGGGCAGTGG CTGTCAAGGG CCCTGTCCAG AGATATCCTG GCAACCAAAC CACCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of Fluticasone Furoate Nasal Spray on Parameters of Eosinophilic Inflammation in Patients With Nasal Polyposis and Perennial Allergic Rhinitis.
The Annals of otology, rhinology, and laryngology126(8)573-580(2017 Aug)
?padijer Mirkovi? C,Peri? A,Vukomanovi? ?ur?evi? B,Vojvodi? D

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
Science translational medicine9(384)(2017 Apr)
von Hundelshausen P,Agten SM,Eckardt V,Blanchet X,Schmitt MM,Ippel H,Neideck C,Bidzhekov K,Leberzammer J,Wichapong K,Faussner A,Drechsler M,Grommes J,van Geffen JP,Li H,Ortega-Gomez A,Megens RT,Naumann R,Dijkgraaf I,Nicolaes GA,D?ring Y,Soehnlein O,Lutgens E,Heemskerk JW,Koenen RR,Mayo KH,Hackeng TM,Weber C

CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis.
Oncotarget8(3)5135-5148(2017 Jan)
Jin L,Liu WR,Tian MX,Jiang XF,Wang H,Zhou PY,Ding ZB,Peng YF,Dai Z,Qiu SJ,Zhou J,Fan J,Shi YH

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CCL24 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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