CCL16 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL16
Entrez Gene ID	6360
Full Name	C-C motif chemokine ligand 16
Synonyms	CKb12,HCC-4,ILINCK,LCC-1,LEC,LMC,Mtn-1,NCC-4,NCC4,SCYA16,SCYL4
General protein information	Preferred Names C-C motif chemokine ligand 16 Names C-C motif chemokine 16 IL-10-inducible chemokine chemokine (C-C motif) ligand 16 chemokine LEC liver CC chemokine-1 liver-expressed chemokine lymphocyte and monocyte chemoattractant monotactin-1 new CC chemokine 4 small inducible cytokine subfamily A (Cys-Cys), member 16 small-inducible cytokine A16
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 17 Map Location: 17q12
Summary	This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008].
Disorder MIM:	601394

mRNA and Protein(s)

mRNA	Protein	Name
XM_005258020.3	XP_005258077.1	C-C motif chemokine 16 isoform X1
NM_004590.3	NP_004581.1	C-C motif chemokine 16 precursor
NM_004590.4	NP_004581.1	C-C motif chemokine 16 precursor
XM_005258020.4	XP_005258077.1	C-C motif chemokine 16 isoform X1
XM_006725334.2	XP_006725397.1	C-C motif chemokine 16 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CCL16	XP_511806.2
Canis lupus familiaris (dog)	CCL16	XP_537724.3
Bos taurus (cattle)	CCL16	XP_002695673.1
Homo sapiens (human)	CCL16	NP_004581.1
	LOC719008	XP_001112513.1

Gene Ontology
Bibliography

Related articles in PubMed

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
von Hundelshausen P, Agten SM, Eckardt V, Blanchet X, Schmitt MM, Ippel H, Neideck C, Bidzhekov K, Leberzammer J, Wichapong K, Faussner A, Drechsler M, Grommes J, van Geffen JP, Li H, Ortega-Gomez A, Megens RT, Naumann R, Dijkgraaf I, Nicolaes GA, D?ring Y, Soehnlein O, Lutgens E, Heemskerk JW, Koenen RR, Mayo KH, Hackeng TM, Weber C
Science translational medicine9(384)(2017 Apr)

Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels.
Ebbert MT, Staley LA, Parker J, Parker S, Bailey M, , Ridge PG, Goate AM, Kauwe JS
BMC genomics17 Suppl 3437(2016 06)

Therapeutic immunization and local low-dose tumor irradiation, a reinforcing combination.
Draghiciu O, Walczak M, Hoogeboom BN, Franken KL, Melief KJ, Nijman HW, Daemen T
International journal of cancer134(4)859-72(2014 Feb)

Expression pattern of serum cytokines in hepatitis B virus infected patients with persistently normal alanine aminotransferase levels.
He D, Li M, Guo S, Zhu P, Huang H, Yan G, Wu Q, Tao S, Tan Z, Wang Y
Journal of clinical immunology33(7)1240-9(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Single nucleotide polymorphism (SNPs) located in and around the C-C motif chemokine ligand 16 (CCL16) gene are associated with CCL16 protein levels in blood plasma, and rs80329614 is the SNP most strongly associated with CCL16 protein levels in plasma.
Title: Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels.

High umbilical artery CCL16 is prominently detected in preterm preeclamptic pregnancies with severe growth restriction.
Title: Umbilical artery chemokine CCL16 is associated with preterm preeclampsia and fetal growth restriction.

Data show that CCL-16 gene expression was upregulated by 7.46-fold in IBS patients when compared with controls and suggest a subclinical inflammatory component underlying IBS.
Title: Pro-inflammatory chemokine C-C motif ligand 16 (CCL-16) dysregulation in irritable bowel syndrome (IBS): a pilot study.

Low umbilical cord blood chemokine CCL16 associates with spontaneous preterm birth
Title: Cord blood chemokines differentiate between spontaneous and elective preterm births in singleton pregnancies.

Observational study of gene-disease association. (HuGE Navigator)
Title: Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.

The following CCL16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04477	NM_004590.4 Latest version!	Homo sapiens C-C motif chemokine ligand 16 (CCL16), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04477	XM_006725334.2 Latest version!	Homo sapiens chemokine (C-C motif) ligand 16 (CCL16), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04477	XM_005258020.4 Latest version!	Homo sapiens C-C motif chemokine ligand 16 (CCL16), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu04477	NM_004590.3	Homo sapiens C-C motif chemokine ligand 16 (CCL16), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04477	XM_005258020.3	Homo sapiens chemokine (C-C motif) ligand 16 (CCL16), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL16 ( NM_004590.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_004581.1 Homo sapiens C-C motif chemokine ligand 16 (CCL16), mRNA.

Price & Availability↑

CloneID	OHu04477
Clone ID Related Accession (Same CDS sequence)	XM_005258020.3 , NM_004590.3 , NM_004590.4 , XM_005258020.4 , XM_006725334.2
Accession Version	NM_004590.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	C-C motif chemokine 16 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB007454.1, AF039955.1, AC244100.3 and BQ722834.1. On Jan 15, 2015 this sequence version replaced NM_004590.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB007454.1, AF039955.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004581.1
CDS	77..439
Translation	MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ

Target ORF information:

RefSeq Version	NM_004590.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 16 (CCL16), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004590.3

ORF Insert Sequence:

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL16 ( NM_004590.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_004581.1 Homo sapiens C-C motif chemokine ligand 16 (CCL16), mRNA.

Price & Availability↑

CloneID	OHu04477
Clone ID Related Accession (Same CDS sequence)	XM_005258020.3 , NM_004590.3 , NM_004590.4 , XM_005258020.4 , XM_006725334.2
Accession Version	NM_004590.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	C-C motif chemokine 16 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC244100.3, AB007454.1 and AF039955.1. On Nov 22, 2018 this sequence version replaced NM_004590.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF039955.1, AB007454.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000611905.2/ ENSP00000478024.1 RefSeq Select criteria :: based on expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004581.1
CDS	78..440
Translation	MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ

Target ORF information:

RefSeq Version	NM_004590.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 16 (CCL16), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004590.4

ORF Insert Sequence:

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL16 ( XM_005258020.3 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005258077.1 Homo sapiens chemokine (C-C motif) ligand 16 (CCL16), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu04477
Clone ID Related Accession (Same CDS sequence)	XM_005258020.3 , NM_004590.3 , NM_004590.4 , XM_005258020.4 , XM_006725334.2
Accession Version	XM_005258020.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	C-C motif chemokine 16 isoform X1
Comment

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258077.1
Translation	MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ

Target ORF information:

RefSeq Version	XM_005258020.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens chemokine (C-C motif) ligand 16 (CCL16), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258020.3

ORF Insert Sequence:

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL16 ( XM_005258020.4 ) cDNA ORF clone, Homo sapiens(Human) -> XP_005258077.1 Homo sapiens C-C motif chemokine ligand 16 (CCL16), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu04477
Clone ID Related Accession (Same CDS sequence)	XM_005258020.3 , NM_004590.3 , NM_004590.4 , XM_005258020.4 , XM_006725334.2
Accession Version	XM_005258020.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	C-C motif chemokine 16 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005258020.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005258077.1
CDS	359..721
Translation	MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ

Target ORF information:

RefSeq Version	XM_005258020.4
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 16 (CCL16), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005258020.4

ORF Insert Sequence:

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL16 ( XM_006725334.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_006725397.1 Homo sapiens chemokine (C-C motif) ligand 16 (CCL16), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu04477
Clone ID Related Accession (Same CDS sequence)	XM_005258020.3 , NM_004590.3 , NM_004590.4 , XM_005258020.4 , XM_006725334.2
Accession Version	XM_006725334.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 363bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	C-C motif chemokine 16 isoform X1
Comment

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006725397.1
Translation	MKVSEAALSLLVLILIITSASRSQPKVPEWVNTPSTCCLKYYEKVLPRRLVVGYRKALNCHLPAIIFVTKRNREVCTNPNDDWVQEYIKDPNLPLLPTRNLSTVKIITAKNGQPQLLNSQ

Target ORF information:

RefSeq Version	XM_006725334.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens chemokine (C-C motif) ligand 16 (CCL16), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006725334.2

ORF Insert Sequence:

ATGAAGGTCT CCGAGGCTGC CCTGTCTCTC CTTGTCCTCA TCCTTATCAT TACTTCGGCT 
TCTCGCAGCC AGCCAAAAGT TCCTGAGTGG GTGAACACCC CATCCACCTG CTGCCTGAAG 
TATTATGAGA AAGTGTTGCC AAGGAGACTA GTGGTGGGAT ACAGAAAGGC CCTCAACTGT 
CACCTGCCAG CAATCATCTT CGTCACCAAG AGGAACCGAG AAGTCTGCAC CAACCCCAAT 
GACGACTGGG TCCAAGAGTA CATCAAGGAT CCCAACCTAC CTTTGCTGCC TACCAGGAAC 
TTGTCCACGG TTAAAATTAT TACAGCAAAG AATGGTCAAC CCCAGCTCCT CAACTCCCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.
Science translational medicine9(384)(2017 Apr)
von Hundelshausen P,Agten SM,Eckardt V,Blanchet X,Schmitt MM,Ippel H,Neideck C,Bidzhekov K,Leberzammer J,Wichapong K,Faussner A,Drechsler M,Grommes J,van Geffen JP,Li H,Ortega-Gomez A,Megens RT,Naumann R,Dijkgraaf I,Nicolaes GA,D?ring Y,Soehnlein O,Lutgens E,Heemskerk JW,Koenen RR,Mayo KH,Hackeng TM,Weber C

Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels.
BMC genomics17 Suppl 3437(2016 06)
Ebbert MT,Staley LA,Parker J,Parker S,Bailey M,,Ridge PG,Goate AM,Kauwe JS

Therapeutic immunization and local low-dose tumor irradiation, a reinforcing combination.
International journal of cancer134(4)859-72(2014 Feb)
Draghiciu O,Walczak M,Hoogeboom BN,Franken KL,Melief KJ,Nijman HW,Daemen T

Expression pattern of serum cytokines in hepatitis B virus infected patients with persistently normal alanine aminotransferase levels.
Journal of clinical immunology33(7)1240-9(2013 Oct)
He D,Li M,Guo S,Zhu P,Huang H,Yan G,Wu Q,Tao S,Tan Z,Wang Y

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CCL16 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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