CCL5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL5
Entrez Gene ID	6352
Full Name	C-C motif chemokine ligand 5
Synonyms	D17S136E,RANTES,SCYA5,SIS-delta,SISd,TCP228,eoCP
General protein information	Preferred Names C-C motif chemokine ligand 5 Names C-C motif chemokine 5 T-cell specific protein p288 beta-chemokine RANTES chemokine (C-C motif) ligand 5 eosinophil chemotactic cytokine regulated upon activation, normally T-expressed, and presumably secreted small inducible cytokine subfamily A (Cys-Cys), member 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q12
Summary	This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].
Disorder MIM:	187011
Disorder Html:	{HIV-1 disease, delayed progression of} (3); {HIV-1 disease, rapid progression of} (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002985.2	NP_002976.2	C-C motif chemokine 5 isoform 1 precursor
NM_001278736.1	NP_001265665.1	C-C motif chemokine 5 isoform 2 precursor
NM_001278736.2	NP_001265665.1	C-C motif chemokine 5 isoform 2 precursor
NM_002985.3	NP_002976.2	C-C motif chemokine 5 isoform 1 precursor

Pathways from BioSystems

Homologies

	CCL5	NP_001028022.1
Homo sapiens (human)	CCL5	NP_002976.2
Gallus gallus (chicken)	CCL5	NP_001039297.1
Bos taurus (cattle)	CCL5	NP_787021.1
Pan troglodytes (chimpanzee)	CCL5	XP_001155572.3
Canis lupus familiaris (dog)	CCL5	NP_001003010.1
Mus musculus (house mouse)	Ccl5	NP_038681.2
Rattus norvegicus (Norway rat)	Ccl5	NP_112378.2

Gene Ontology
Bibliography

Related articles in PubMed

The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors.
Brau? TF, Winslow S, Lampe S, Scholz A, Weigert A, Dehne N, von Stedingk K, Schmid T, Br?ne B
Molecular carcinogenesis56(12)2620-2629(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mean RANTES concentrations in nasal fluid in patients with perennial allergic rhinitis and nonallergic and allergic chronic rhinosinusitis with nasal polyps patients were significantly higher in comparison to control subjects.
Title: Effects of Fluticasone Furoate Nasal Spray on Parameters of Eosinophilic Inflammation in Patients With Nasal Polyposis and Perennial Allergic Rhinitis.

Findings show the significant upregulated expression of chemokine CCL5 (RANTES) in plasma, compared to CSF and contused brain tissue following severe traumatic brain injury (TBI).
Title: RANTES levels in peripheral blood, CSF and contused brain tissue as a marker for outcome in traumatic brain injury (TBI) patients.

Intermolecular interactions of RANTES with its receptor CCR5 have been reported based on NMR spectroscopy measurements.
Title: Detection of intermolecular transferred-NOE interactions in small and medium size protein complexes: RANTES complexed with a CCR5 N-terminal peptide.

IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer
Title: IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer.

These data indicate that ECFCs, not SPCs, are the major players in MMD pathogenesis and that the chemokine CCL5 mediates the interactions. It can be hypothesized that in MMD patients, defective ECFCs direct aberrant SPC recruitment to critical vascular locations through the action of CCL5.
Title: Chemokine Ligand 5 (CCL5) Derived from Endothelial Colony-Forming Cells (ECFCs) Mediates Recruitment of Smooth Muscle Progenitor Cells (SPCs) toward Critical Vascular Locations in Moyamoya Disease.

The following CCL5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20442	NM_002985.3 Latest version!	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20423	NM_001278736.2 Latest version!	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu20423	NM_001278736.1	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu20442	NM_002985.2	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL5 ( NM_002985.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002976.2 Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20442
Clone ID Related Accession (Same CDS sequence)	NM_002985.2 , NM_002985.3
Accession Version	NM_002985.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-09
Organism	Homo sapiens(human)
Product	C-C motif chemokine 5 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD695497.1, BC008600.1, AA486131.1, AA443491.1, AW769950.1 and BG272739.1. This sequence is a reference standard in the RefSeqGene project. On Aug 29, 2002 this sequence version replaced NM_002985.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.131158.1, M21121.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150385, SAMN01820687 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCT TTGTCACCCG AAAGAACCGC CAAGTGTGTG CCAACCCAGA GAAGAAATGG 
GTTCGGGAGT ACATCAACTC TTTGGAGATG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002976.2
CDS	69..344
Translation	MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS

Target ORF information:

RefSeq Version	NM_002985.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002985.2

ORF Insert Sequence:

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCT TTGTCACCCG AAAGAACCGC CAAGTGTGTG CCAACCCAGA GAAGAAATGG 
GTTCGGGAGT ACATCAACTC TTTGGAGATG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL5 ( NM_002985.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002976.2 Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20442
Clone ID Related Accession (Same CDS sequence)	NM_002985.2 , NM_002985.3
Accession Version	NM_002985.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	C-C motif chemokine 5 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD695497.1, BC008600.1, AA486131.1, AA443491.1, AW769950.1 and BG272739.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_002985.2. Transcript Variant: This variant (1) represents the shorter transcript and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.83807.1, DRR138524.125927.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150385, SAMN01820687 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCT TTGTCACCCG AAAGAACCGC CAAGTGTGTG CCAACCCAGA GAAGAAATGG 
GTTCGGGAGT ACATCAACTC TTTGGAGATG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002976.2
CDS	56..331
Translation	MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS

Target ORF information:

RefSeq Version	NM_002985.3
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002985.3

ORF Insert Sequence:

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCT TTGTCACCCG AAAGAACCGC CAAGTGTGTG CCAACCCAGA GAAGAAATGG 
GTTCGGGAGT ACATCAACTC TTTGGAGATG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL5 ( NM_001278736.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265665.1 Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20423
Clone ID Related Accession (Same CDS sequence)	NM_001278736.1 , NM_001278736.2
Accession Version	NM_001278736.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	C-C motif chemokine 5 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD695497.1, CR980938.1, CB111656.1, HY265548.1, AA443491.1, AW769950.1, GD136908.1 and BG272739.1. Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a longer and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.49186.1, SRR1163655.600143.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCC ACAGGTCAAG GATGCCAAAG AGAGAGGGAC AGCAAGTCTG GCAGGATTTC 
CTGTATGACT CCCGGCTGAA CAAGGGCAAG CTTTGTCACC CGAAAGAACC GCCAAGTGTG 
TGCCAACCCA GAGAAGAAAT GGGTTCGGGA GTACATCAAC TCTTTGGAGA TGAGCTAGGA 
TGGAGAGTCC TTGAACCTGA ACTTACACAA ATTTGCCTGT TTCTGCTTGC TCTTGTCCTA 
GCTTGGGAGG CTTCCCCTCA CTATCCTACC CCACCCGCTC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265665.1
CDS	69..533
Translation	MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVHRSRMPKREGQQVWQDFLYDSRLNKGKLCHPKEPPSVCQPREEMGSGVHQLFGDELGWRVLEPELTQICLFLLALVLAWEASPHYPTPPAP

Target ORF information:

RefSeq Version	NM_001278736.1
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278736.1

ORF Insert Sequence:

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCC ACAGGTCAAG GATGCCAAAG AGAGAGGGAC AGCAAGTCTG GCAGGATTTC 
CTGTATGACT CCCGGCTGAA CAAGGGCAAG CTTTGTCACC CGAAAGAACC GCCAAGTGTG 
TGCCAACCCA GAGAAGAAAT GGGTTCGGGA GTACATCAAC TCTTTGGAGA TGAGCTAGGA 
TGGAGAGTCC TTGAACCTGA ACTTACACAA ATTTGCCTGT TTCTGCTTGC TCTTGTCCTA 
GCTTGGGAGG CTTCCCCTCA CTATCCTACC CCACCCGCTC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL5 ( NM_001278736.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265665.1 Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20423
Clone ID Related Accession (Same CDS sequence)	NM_001278736.1 , NM_001278736.2
Accession Version	NM_001278736.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 465bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-22
Organism	Homo sapiens(human)
Product	C-C motif chemokine 5 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD695497.1, CR980938.1, CB111656.1, HY265548.1, AA443491.1, AW769950.1, GD136908.1 and BG272739.1. On Nov 23, 2018 this sequence version replaced NM_001278736.1. Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a longer and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR980938.1, SRR1163657.348271.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000651122.1/ ENSP00000499138.1 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCC ACAGGTCAAG GATGCCAAAG AGAGAGGGAC AGCAAGTCTG GCAGGATTTC 
CTGTATGACT CCCGGCTGAA CAAGGGCAAG CTTTGTCACC CGAAAGAACC GCCAAGTGTG 
TGCCAACCCA GAGAAGAAAT GGGTTCGGGA GTACATCAAC TCTTTGGAGA TGAGCTAGGA 
TGGAGAGTCC TTGAACCTGA ACTTACACAA ATTTGCCTGT TTCTGCTTGC TCTTGTCCTA 
GCTTGGGAGG CTTCCCCTCA CTATCCTACC CCACCCGCTC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265665.1
CDS	56..520
Translation	MKVSAAALAVILIATALCAPASASPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVHRSRMPKREGQQVWQDFLYDSRLNKGKLCHPKEPPSVCQPREEMGSGVHQLFGDELGWRVLEPELTQICLFLLALVLAWEASPHYPTPPAP

Target ORF information:

RefSeq Version	NM_001278736.2
Organism	Homo sapiens(human)
Definition	Homo sapiens C-C motif chemokine ligand 5 (CCL5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278736.2

ORF Insert Sequence:

ATGAAGGTCT CCGCGGCAGC CCTCGCTGTC ATCCTCATTG CTACTGCCCT CTGCGCTCCT 
GCATCTGCCT CCCCATATTC CTCGGACACC ACACCCTGCT GCTTTGCCTA CATTGCCCGC 
CCACTGCCCC GTGCCCACAT CAAGGAGTAT TTCTACACCA GTGGCAAGTG CTCCAACCCA 
GCAGTCGTCC ACAGGTCAAG GATGCCAAAG AGAGAGGGAC AGCAAGTCTG GCAGGATTTC 
CTGTATGACT CCCGGCTGAA CAAGGGCAAG CTTTGTCACC CGAAAGAACC GCCAAGTGTG 
TGCCAACCCA GAGAAGAAAT GGGTTCGGGA GTACATCAAC TCTTTGGAGA TGAGCTAGGA 
TGGAGAGTCC TTGAACCTGA ACTTACACAA ATTTGCCTGT TTCTGCTTGC TCTTGTCCTA 
GCTTGGGAGG CTTCCCCTCA CTATCCTACC CCACCCGCTC CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors.
Molecular carcinogenesis56(12)2620-2629(2017 Dec)
Brau? TF,Winslow S,Lampe S,Scholz A,Weigert A,Dehne N,von Stedingk K,Schmid T,Br?ne B

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CCL5 cDNA ORF clone, Homo sapiens(human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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