ATXN1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATXN1
Entrez Gene ID	6310
Full Name	ataxin 1
Synonyms	ATX1,D6S504E,SCA1
General protein information	Preferred Names ataxin 1 Names ataxin-1 alternative ataxin1 spinocerebellar ataxia type 1 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.3
Summary	The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 40-83 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). Alternative splicing results in multiple transcript variants, with one variant encoding multiple distinct proteins, ATXN1 and Alt-ATXN1, due to the use of overlapping alternate reading frames. [provided by RefSeq, Nov 2017].
Disorder MIM:	601556
Disorder Html:	Spinocerebellar ataxia 1, 164400 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001357857.1	NP_001344786.1	ataxin-1 Alt-ATXN1
NM_001357857.2	NP_001344786.1	ataxin-1 Alt-ATXN1
NM_001128164.1	NP_001121636.1	ataxin-1 ATXN1
NM_000332.3	NP_000323.2	ataxin-1 ATXN1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ATXN1	NP_001121636.1
Rattus norvegicus (Norway rat)	Atxn1	NP_036858.1
Xenopus tropicalis (tropical clawed frog)	atxn1	XP_004915340.1
Pan troglodytes (chimpanzee)	ATXN1	XP_003311077.1
Bos taurus (cattle)	ATXN1	XP_005223892.1
Mus musculus (house mouse)	Atxn1	NP_001186234.1
Danio rerio (zebrafish)	atxn1a	NP_001038291.1
Canis lupus familiaris (dog)	ATXN1	XP_545354.2
Gallus gallus (chicken)	ATXN1	XP_003640803.1

Gene Ontology
Bibliography

Related articles in PubMed

ATXN1 intermediate-length polyglutamine expansions are associated with amyotrophic lateral sclerosis.
Lattante S, Pomponi MG, Conte A, Marangi G, Bisogni G, Patanella AK, Meleo E, Lunetta C, Riva N, Mosca L, Carrera P, Bee M, Zollino M, Sabatelli M
Neurobiology of aging(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In cervical cancer cells, ATXN1 knockdown induced EMT by directly regulating Snail expression, leading to matrix metalloproteinase activation and the promotion of cell migration and invasion.
Title: Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells.

ATXN1 underexpression is associated with metabolic diseases.
Title: Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.

SCA1 phenotypes could be reversed by partial suppression of human mutant ATXN1 mRNA by rAAV.miS1 when delivered after symptom onset in mice.
Title: RNAi prevents and reverses phenotypes induced by mutant human ataxin-1.

Data indicate that in spinocerebellar ataxia type 1 patients the spinocerebellar ataxia type 1 protein trinucleotide repeat expansion (CAG)n was great than 39, comparing with normal 6-38.
Title: [Spinocerebellar ataxia: eight cases from one pedigree].

data suggest GSK3b and mTOR pathways modulate this ATXN1 function in spinocerebellar ataxia type-1 (SCA1)pathogenesis that could be targeted therapeutically prior to the onset of disease symptoms in SCA1 and other pathologies involving dysregulation of ATXN1 functions.
Title: Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3?-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).

The following ATXN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATXN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26181	NM_001128164.1 Latest version!	Homo sapiens ataxin 1 (ATXN1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu26181	NM_000332.3 Latest version!	Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu102879	NM_001357857.2 Latest version!	Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu102879	NM_001357857.1	Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATXN1 ( NM_001128164.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001121636.1 Homo sapiens ataxin 1 (ATXN1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26181
Clone ID Related Accession (Same CDS sequence)	NM_001128164.1 , NM_000332.3
Accession Version	NM_001128164.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2448bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	ataxin-1 ATXN1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011026.1, BP365416.1, X79204.1 and AL009031.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. This variant encodes the same protein represented by the longer protein encoded by variant 1, ATXN1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: X79204.1, BC117125.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAATCCA ACCAAGAGCG GAGCAACGAA TGCCTGCCTC CCAAGAAGCG CGAGATCCCC 
GCCACCAGCC GGTCCTCCGA GGAGAAGGCC CCTACCCTGC CCAGCGACAA CCACCGGGTG 
GAGGGCACAG CATGGCTCCC GGGCAACCCT GGTGGCCGGG GCCACGGGGG CGGGAGGCAT 
GGGCCGGCAG GGACCTCGGT GGAGCTTGGT TTACAACAGG GAATAGGTTT ACACAAAGCA 
TTGTCCACAG GGCTGGACTA CTCCCCGCCC AGCGCTCCCA GGTCTGTCCC CGTGGCCACC 
ACGCTGCCTG CCGCGTACGC CACCCCGCAG CCAGGGACCC CGGTGTCCCC CGTGCAGTAC 
GCTCACCTGC CGCACACCTT CCAGTTCATT GGGTCCTCCC AATACAGTGG AACCTATGCC 
AGCTTCATCC CATCACAGCT GATCCCCCCA ACCGCCAACC CCGTCACCAG TGCAGTGGCC 
TCGGCCGCAG GGGCCACCAC TCCATCCCAG CGCTCCCAGC TGGAGGCCTA TTCCACTCTG 
CTGGCCAACA TGGGCAGTCT GAGCCAGACG CCGGGACACA AGGCTGAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCAGCA GCAGCATCAG CATCAGCAGC AGCAGCAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCACCT CAGCAGGGCT CCGGGGCTCA TCACCCCGGG GTCCCCCCCA 
CCAGCCCAGC AGAACCAGTA CGTCCACATT TCCAGTTCTC CGCAGAACAC CGGCCGCACC 
GCCTCTCCTC CGGCCATCCC CGTCCACCTC CACCCCCACC AGACGATGAT CCCACACACG 
CTCACCCTGG GGCCCCCCTC CCAGGTCGTC ATGCAATACG CCGACTCCGG CAGCCACTTT 
GTCCCTCGGG AGGCCACCAA GAAAGCTGAG AGCAGCCGGC TGCAGCAGGC CATCCAGGCC 
AAGGAGGTCC TGAACGGTGA GATGGAGAAG AGCCGGCGGT ACGGGGCCCC GTCCTCAGCC 
GACCTGGGCC TGGGCAAGGC AGGCGGCAAG TCGGTTCCTC ACCCGTACGA GTCCAGGCAC 
GTGGTGGTCC ACCCGAGCCC CTCAGACTAC AGCAGTCGTG ATCCTTCGGG GGTCCGGGCC 
TCTGTGATGG TCCTGCCCAA CAGCAACACG CCCGCAGCTG ACCTGGAGGT GCAACAGGCC 
ACTCATCGTG AAGCCTCCCC TTCTACCCTC AACGACAAAA GTGGCCTGCA TTTAGGGAAG 
CCTGGCCACC GGTCCTACGC GCTCTCACCC CACACGGTCA TTCAGACCAC ACACAGTGCT 
TCAGAGCCAC TCCCGGTGGG ACTGCCAGCC ACGGCCTTCT ACGCAGGGAC TCAACCCCCT 
GTCATCGGCT ACCTGAGCGG CCAGCAGCAA GCAATCACCT ACGCCGGCAG CCTGCCCCAG 
CACCTGGTGA TCCCCGGCAC ACAGCCCCTG CTCATCCCGG TCGGCAGCAC TGACATGGAA 
GCGTCGGGGG CAGCCCCGGC CATAGTCACG TCATCCCCCC AGTTTGCTGC AGTGCCTCAC 
ACGTTCGTCA CCACCGCCCT TCCCAAGAGC GAGAACTTCA ACCCTGAGGC CCTGGTCACC 
CAGGCCGCCT ACCCAGCCAT GGTGCAGGCC CAGATCCACC TGCCTGTGGT GCAGTCCGTG 
GCCTCCCCGG CGGCGGCTCC CCCTACGCTG CCTCCCTACT TCATGAAAGG CTCCATCATC 
CAGTTGGCCA ACGGGGAGCT AAAGAAGGTG GAAGACTTAA AAACAGAAGA TTTCATCCAG 
AGTGCAGAGA TAAGCAACGA CCTGAAGATC GACTCCAGCA CCGTAGAGAG GATTGAAGAC 
AGCCATAGCC CGGGCGTGGC CGTGATACAG TTCGCCGTCG GGGAGCACCG AGCCCAGGTC 
AGCGTTGAAG TTTTGGTAGA GTATCCTTTT TTTGTGTTTG GACAGGGCTG GTCATCCTGC 
TGTCCGGAGA GAACCAGCCA GCTCTTTGAT TTGCCGTGTT CCAAACTCTC AGTTGGGGAT 
GTCTGCATCT CGCTTACCCT CAAGAACCTG AAGAACGGCT CTGTTAAAAA GGGCCAGCCC 
GTGGATCCCG CCAGCGTCCT GCTGAAGCAC TCAAAGGCCG ACGGCCTGGC GGGCAGCAGA 
CACAGGTATG CCGAGCAGGA AAACGGAATC AACCAGGGGA GTGCCCAGAT GCTCTCTGAG 
AATGGCGAAC TGAAGTTTCC AGAGAAAATG GGATTGCCTG CAGCGCCCTT CCTCACCAAA 
ATAGAACCCA GCAAGCCCGC GGCAACGAGG AAGAGGAGGT GGTCGGCGCC AGAGAGCCGC 
AAACTGGAGA AGTCAGAAGA CGAACCACCT TTGACTCTTC CTAAGCCTTC TCTAATTCCT 
CAGGAGGTTA AGATTTGCAT TGAAGGCCGG TCTAATGTAG GCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121636.1
CDS	923..3370
Translation	MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK

Target ORF information:

RefSeq Version	NM_001128164.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ataxin 1 (ATXN1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001128164.1

ORF Insert Sequence:

ATGAAATCCA ACCAAGAGCG GAGCAACGAA TGCCTGCCTC CCAAGAAGCG CGAGATCCCC 
GCCACCAGCC GGTCCTCCGA GGAGAAGGCC CCTACCCTGC CCAGCGACAA CCACCGGGTG 
GAGGGCACAG CATGGCTCCC GGGCAACCCT GGTGGCCGGG GCCACGGGGG CGGGAGGCAT 
GGGCCGGCAG GGACCTCGGT GGAGCTTGGT TTACAACAGG GAATAGGTTT ACACAAAGCA 
TTGTCCACAG GGCTGGACTA CTCCCCGCCC AGCGCTCCCA GGTCTGTCCC CGTGGCCACC 
ACGCTGCCTG CCGCGTACGC CACCCCGCAG CCAGGGACCC CGGTGTCCCC CGTGCAGTAC 
GCTCACCTGC CGCACACCTT CCAGTTCATT GGGTCCTCCC AATACAGTGG AACCTATGCC 
AGCTTCATCC CATCACAGCT GATCCCCCCA ACCGCCAACC CCGTCACCAG TGCAGTGGCC 
TCGGCCGCAG GGGCCACCAC TCCATCCCAG CGCTCCCAGC TGGAGGCCTA TTCCACTCTG 
CTGGCCAACA TGGGCAGTCT GAGCCAGACG CCGGGACACA AGGCTGAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCAGCA GCAGCATCAG CATCAGCAGC AGCAGCAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCACCT CAGCAGGGCT CCGGGGCTCA TCACCCCGGG GTCCCCCCCA 
CCAGCCCAGC AGAACCAGTA CGTCCACATT TCCAGTTCTC CGCAGAACAC CGGCCGCACC 
GCCTCTCCTC CGGCCATCCC CGTCCACCTC CACCCCCACC AGACGATGAT CCCACACACG 
CTCACCCTGG GGCCCCCCTC CCAGGTCGTC ATGCAATACG CCGACTCCGG CAGCCACTTT 
GTCCCTCGGG AGGCCACCAA GAAAGCTGAG AGCAGCCGGC TGCAGCAGGC CATCCAGGCC 
AAGGAGGTCC TGAACGGTGA GATGGAGAAG AGCCGGCGGT ACGGGGCCCC GTCCTCAGCC 
GACCTGGGCC TGGGCAAGGC AGGCGGCAAG TCGGTTCCTC ACCCGTACGA GTCCAGGCAC 
GTGGTGGTCC ACCCGAGCCC CTCAGACTAC AGCAGTCGTG ATCCTTCGGG GGTCCGGGCC 
TCTGTGATGG TCCTGCCCAA CAGCAACACG CCCGCAGCTG ACCTGGAGGT GCAACAGGCC 
ACTCATCGTG AAGCCTCCCC TTCTACCCTC AACGACAAAA GTGGCCTGCA TTTAGGGAAG 
CCTGGCCACC GGTCCTACGC GCTCTCACCC CACACGGTCA TTCAGACCAC ACACAGTGCT 
TCAGAGCCAC TCCCGGTGGG ACTGCCAGCC ACGGCCTTCT ACGCAGGGAC TCAACCCCCT 
GTCATCGGCT ACCTGAGCGG CCAGCAGCAA GCAATCACCT ACGCCGGCAG CCTGCCCCAG 
CACCTGGTGA TCCCCGGCAC ACAGCCCCTG CTCATCCCGG TCGGCAGCAC TGACATGGAA 
GCGTCGGGGG CAGCCCCGGC CATAGTCACG TCATCCCCCC AGTTTGCTGC AGTGCCTCAC 
ACGTTCGTCA CCACCGCCCT TCCCAAGAGC GAGAACTTCA ACCCTGAGGC CCTGGTCACC 
CAGGCCGCCT ACCCAGCCAT GGTGCAGGCC CAGATCCACC TGCCTGTGGT GCAGTCCGTG 
GCCTCCCCGG CGGCGGCTCC CCCTACGCTG CCTCCCTACT TCATGAAAGG CTCCATCATC 
CAGTTGGCCA ACGGGGAGCT AAAGAAGGTG GAAGACTTAA AAACAGAAGA TTTCATCCAG 
AGTGCAGAGA TAAGCAACGA CCTGAAGATC GACTCCAGCA CCGTAGAGAG GATTGAAGAC 
AGCCATAGCC CGGGCGTGGC CGTGATACAG TTCGCCGTCG GGGAGCACCG AGCCCAGGTC 
AGCGTTGAAG TTTTGGTAGA GTATCCTTTT TTTGTGTTTG GACAGGGCTG GTCATCCTGC 
TGTCCGGAGA GAACCAGCCA GCTCTTTGAT TTGCCGTGTT CCAAACTCTC AGTTGGGGAT 
GTCTGCATCT CGCTTACCCT CAAGAACCTG AAGAACGGCT CTGTTAAAAA GGGCCAGCCC 
GTGGATCCCG CCAGCGTCCT GCTGAAGCAC TCAAAGGCCG ACGGCCTGGC GGGCAGCAGA 
CACAGGTATG CCGAGCAGGA AAACGGAATC AACCAGGGGA GTGCCCAGAT GCTCTCTGAG 
AATGGCGAAC TGAAGTTTCC AGAGAAAATG GGATTGCCTG CAGCGCCCTT CCTCACCAAA 
ATAGAACCCA GCAAGCCCGC GGCAACGAGG AAGAGGAGGT GGTCGGCGCC AGAGAGCCGC 
AAACTGGAGA AGTCAGAAGA CGAACCACCT TTGACTCTTC CTAAGCCTTC TCTAATTCCT 
CAGGAGGTTA AGATTTGCAT TGAAGGCCGG TCTAATGTAG GCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATXN1 ( NM_000332.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000323.2 Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26181
Clone ID Related Accession (Same CDS sequence)	NM_001128164.1 , NM_000332.3
Accession Version	NM_000332.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2448bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	ataxin-1 ATXN1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011026.1, X79204.1 and AL009031.1. This sequence is a reference standard in the RefSeqGene project. On Jun 8, 2008 this sequence version replaced NM_000332.2. Transcript Variant: This variant (1) encodes multiple distinct proteins due to the use of alternative translation initiation codons. The longer 815 aa protein (ATXN1, PMID:23705062) represents the canonical protein, while a shorter protein (Alt-ATXN1, PMID:23705062) that uses a different reading frame has also been described. This RefSeq represents the longer protein, ATXN1. Variant 2 also encodes ATXN1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X79204.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAATCCA ACCAAGAGCG GAGCAACGAA TGCCTGCCTC CCAAGAAGCG CGAGATCCCC 
GCCACCAGCC GGTCCTCCGA GGAGAAGGCC CCTACCCTGC CCAGCGACAA CCACCGGGTG 
GAGGGCACAG CATGGCTCCC GGGCAACCCT GGTGGCCGGG GCCACGGGGG CGGGAGGCAT 
GGGCCGGCAG GGACCTCGGT GGAGCTTGGT TTACAACAGG GAATAGGTTT ACACAAAGCA 
TTGTCCACAG GGCTGGACTA CTCCCCGCCC AGCGCTCCCA GGTCTGTCCC CGTGGCCACC 
ACGCTGCCTG CCGCGTACGC CACCCCGCAG CCAGGGACCC CGGTGTCCCC CGTGCAGTAC 
GCTCACCTGC CGCACACCTT CCAGTTCATT GGGTCCTCCC AATACAGTGG AACCTATGCC 
AGCTTCATCC CATCACAGCT GATCCCCCCA ACCGCCAACC CCGTCACCAG TGCAGTGGCC 
TCGGCCGCAG GGGCCACCAC TCCATCCCAG CGCTCCCAGC TGGAGGCCTA TTCCACTCTG 
CTGGCCAACA TGGGCAGTCT GAGCCAGACG CCGGGACACA AGGCTGAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCAGCA GCAGCATCAG CATCAGCAGC AGCAGCAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCACCT CAGCAGGGCT CCGGGGCTCA TCACCCCGGG GTCCCCCCCA 
CCAGCCCAGC AGAACCAGTA CGTCCACATT TCCAGTTCTC CGCAGAACAC CGGCCGCACC 
GCCTCTCCTC CGGCCATCCC CGTCCACCTC CACCCCCACC AGACGATGAT CCCACACACG 
CTCACCCTGG GGCCCCCCTC CCAGGTCGTC ATGCAATACG CCGACTCCGG CAGCCACTTT 
GTCCCTCGGG AGGCCACCAA GAAAGCTGAG AGCAGCCGGC TGCAGCAGGC CATCCAGGCC 
AAGGAGGTCC TGAACGGTGA GATGGAGAAG AGCCGGCGGT ACGGGGCCCC GTCCTCAGCC 
GACCTGGGCC TGGGCAAGGC AGGCGGCAAG TCGGTTCCTC ACCCGTACGA GTCCAGGCAC 
GTGGTGGTCC ACCCGAGCCC CTCAGACTAC AGCAGTCGTG ATCCTTCGGG GGTCCGGGCC 
TCTGTGATGG TCCTGCCCAA CAGCAACACG CCCGCAGCTG ACCTGGAGGT GCAACAGGCC 
ACTCATCGTG AAGCCTCCCC TTCTACCCTC AACGACAAAA GTGGCCTGCA TTTAGGGAAG 
CCTGGCCACC GGTCCTACGC GCTCTCACCC CACACGGTCA TTCAGACCAC ACACAGTGCT 
TCAGAGCCAC TCCCGGTGGG ACTGCCAGCC ACGGCCTTCT ACGCAGGGAC TCAACCCCCT 
GTCATCGGCT ACCTGAGCGG CCAGCAGCAA GCAATCACCT ACGCCGGCAG CCTGCCCCAG 
CACCTGGTGA TCCCCGGCAC ACAGCCCCTG CTCATCCCGG TCGGCAGCAC TGACATGGAA 
GCGTCGGGGG CAGCCCCGGC CATAGTCACG TCATCCCCCC AGTTTGCTGC AGTGCCTCAC 
ACGTTCGTCA CCACCGCCCT TCCCAAGAGC GAGAACTTCA ACCCTGAGGC CCTGGTCACC 
CAGGCCGCCT ACCCAGCCAT GGTGCAGGCC CAGATCCACC TGCCTGTGGT GCAGTCCGTG 
GCCTCCCCGG CGGCGGCTCC CCCTACGCTG CCTCCCTACT TCATGAAAGG CTCCATCATC 
CAGTTGGCCA ACGGGGAGCT AAAGAAGGTG GAAGACTTAA AAACAGAAGA TTTCATCCAG 
AGTGCAGAGA TAAGCAACGA CCTGAAGATC GACTCCAGCA CCGTAGAGAG GATTGAAGAC 
AGCCATAGCC CGGGCGTGGC CGTGATACAG TTCGCCGTCG GGGAGCACCG AGCCCAGGTC 
AGCGTTGAAG TTTTGGTAGA GTATCCTTTT TTTGTGTTTG GACAGGGCTG GTCATCCTGC 
TGTCCGGAGA GAACCAGCCA GCTCTTTGAT TTGCCGTGTT CCAAACTCTC AGTTGGGGAT 
GTCTGCATCT CGCTTACCCT CAAGAACCTG AAGAACGGCT CTGTTAAAAA GGGCCAGCCC 
GTGGATCCCG CCAGCGTCCT GCTGAAGCAC TCAAAGGCCG ACGGCCTGGC GGGCAGCAGA 
CACAGGTATG CCGAGCAGGA AAACGGAATC AACCAGGGGA GTGCCCAGAT GCTCTCTGAG 
AATGGCGAAC TGAAGTTTCC AGAGAAAATG GGATTGCCTG CAGCGCCCTT CCTCACCAAA 
ATAGAACCCA GCAAGCCCGC GGCAACGAGG AAGAGGAGGT GGTCGGCGCC AGAGAGCCGC 
AAACTGGAGA AGTCAGAAGA CGAACCACCT TTGACTCTTC CTAAGCCTTC TCTAATTCCT 
CAGGAGGTTA AGATTTGCAT TGAAGGCCGG TCTAATGTAG GCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000323.2
CDS	972..3419
Translation	MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK

Target ORF information:

RefSeq Version	NM_000332.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000332.3

ORF Insert Sequence:

ATGAAATCCA ACCAAGAGCG GAGCAACGAA TGCCTGCCTC CCAAGAAGCG CGAGATCCCC 
GCCACCAGCC GGTCCTCCGA GGAGAAGGCC CCTACCCTGC CCAGCGACAA CCACCGGGTG 
GAGGGCACAG CATGGCTCCC GGGCAACCCT GGTGGCCGGG GCCACGGGGG CGGGAGGCAT 
GGGCCGGCAG GGACCTCGGT GGAGCTTGGT TTACAACAGG GAATAGGTTT ACACAAAGCA 
TTGTCCACAG GGCTGGACTA CTCCCCGCCC AGCGCTCCCA GGTCTGTCCC CGTGGCCACC 
ACGCTGCCTG CCGCGTACGC CACCCCGCAG CCAGGGACCC CGGTGTCCCC CGTGCAGTAC 
GCTCACCTGC CGCACACCTT CCAGTTCATT GGGTCCTCCC AATACAGTGG AACCTATGCC 
AGCTTCATCC CATCACAGCT GATCCCCCCA ACCGCCAACC CCGTCACCAG TGCAGTGGCC 
TCGGCCGCAG GGGCCACCAC TCCATCCCAG CGCTCCCAGC TGGAGGCCTA TTCCACTCTG 
CTGGCCAACA TGGGCAGTCT GAGCCAGACG CCGGGACACA AGGCTGAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCAGCA GCAGCATCAG CATCAGCAGC AGCAGCAGCA GCAGCAGCAG 
CAGCAGCAGC AGCAGCACCT CAGCAGGGCT CCGGGGCTCA TCACCCCGGG GTCCCCCCCA 
CCAGCCCAGC AGAACCAGTA CGTCCACATT TCCAGTTCTC CGCAGAACAC CGGCCGCACC 
GCCTCTCCTC CGGCCATCCC CGTCCACCTC CACCCCCACC AGACGATGAT CCCACACACG 
CTCACCCTGG GGCCCCCCTC CCAGGTCGTC ATGCAATACG CCGACTCCGG CAGCCACTTT 
GTCCCTCGGG AGGCCACCAA GAAAGCTGAG AGCAGCCGGC TGCAGCAGGC CATCCAGGCC 
AAGGAGGTCC TGAACGGTGA GATGGAGAAG AGCCGGCGGT ACGGGGCCCC GTCCTCAGCC 
GACCTGGGCC TGGGCAAGGC AGGCGGCAAG TCGGTTCCTC ACCCGTACGA GTCCAGGCAC 
GTGGTGGTCC ACCCGAGCCC CTCAGACTAC AGCAGTCGTG ATCCTTCGGG GGTCCGGGCC 
TCTGTGATGG TCCTGCCCAA CAGCAACACG CCCGCAGCTG ACCTGGAGGT GCAACAGGCC 
ACTCATCGTG AAGCCTCCCC TTCTACCCTC AACGACAAAA GTGGCCTGCA TTTAGGGAAG 
CCTGGCCACC GGTCCTACGC GCTCTCACCC CACACGGTCA TTCAGACCAC ACACAGTGCT 
TCAGAGCCAC TCCCGGTGGG ACTGCCAGCC ACGGCCTTCT ACGCAGGGAC TCAACCCCCT 
GTCATCGGCT ACCTGAGCGG CCAGCAGCAA GCAATCACCT ACGCCGGCAG CCTGCCCCAG 
CACCTGGTGA TCCCCGGCAC ACAGCCCCTG CTCATCCCGG TCGGCAGCAC TGACATGGAA 
GCGTCGGGGG CAGCCCCGGC CATAGTCACG TCATCCCCCC AGTTTGCTGC AGTGCCTCAC 
ACGTTCGTCA CCACCGCCCT TCCCAAGAGC GAGAACTTCA ACCCTGAGGC CCTGGTCACC 
CAGGCCGCCT ACCCAGCCAT GGTGCAGGCC CAGATCCACC TGCCTGTGGT GCAGTCCGTG 
GCCTCCCCGG CGGCGGCTCC CCCTACGCTG CCTCCCTACT TCATGAAAGG CTCCATCATC 
CAGTTGGCCA ACGGGGAGCT AAAGAAGGTG GAAGACTTAA AAACAGAAGA TTTCATCCAG 
AGTGCAGAGA TAAGCAACGA CCTGAAGATC GACTCCAGCA CCGTAGAGAG GATTGAAGAC 
AGCCATAGCC CGGGCGTGGC CGTGATACAG TTCGCCGTCG GGGAGCACCG AGCCCAGGTC 
AGCGTTGAAG TTTTGGTAGA GTATCCTTTT TTTGTGTTTG GACAGGGCTG GTCATCCTGC 
TGTCCGGAGA GAACCAGCCA GCTCTTTGAT TTGCCGTGTT CCAAACTCTC AGTTGGGGAT 
GTCTGCATCT CGCTTACCCT CAAGAACCTG AAGAACGGCT CTGTTAAAAA GGGCCAGCCC 
GTGGATCCCG CCAGCGTCCT GCTGAAGCAC TCAAAGGCCG ACGGCCTGGC GGGCAGCAGA 
CACAGGTATG CCGAGCAGGA AAACGGAATC AACCAGGGGA GTGCCCAGAT GCTCTCTGAG 
AATGGCGAAC TGAAGTTTCC AGAGAAAATG GGATTGCCTG CAGCGCCCTT CCTCACCAAA 
ATAGAACCCA GCAAGCCCGC GGCAACGAGG AAGAGGAGGT GGTCGGCGCC AGAGAGCCGC 
AAACTGGAGA AGTCAGAAGA CGAACCACCT TTGACTCTTC CTAAGCCTTC TCTAATTCCT 
CAGGAGGTTA AGATTTGCAT TGAAGGCCGG TCTAATGTAG GCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATXN1 ( NM_001357857.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001344786.1 Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.

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CloneID	OHu102879
Clone ID Related Accession (Same CDS sequence)	NM_001357857.1 , NM_001357857.2
Accession Version	NM_001357857.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	ataxin-1 Alt-ATXN1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011026.1, X79204.1 and AL009031.1. Transcript Variant: This variant (1) encodes multiple distinct proteins due to the use of alternative translation initiation codons. The longer, 815 aa protein represents the canonical protein, while a shorter 185 aa protein(Alt-ATXN1, PMID:23760502) that uses a different reading frame has also been described. Alt-ATXN1 does not share structural similarity to the ATXN1, but has been shown to interact with the ATXN1. This RefSeq represents the shorter protein, Alt-ATXN1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X79204.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: PMID: 23760502 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT CCCAAGAAGC GCGAGATCCC CGCCACCAGC CGGTCCTCCG AGGAGAAGGC 
CCCTACCCTG CCCAGCGACA ACCACCGGGT GGAGGGCACA GCATGGCTCC CGGGCAACCC 
TGGTGGCCGG GGCCACGGGG GCGGGAGGCA TGGGCCGGCA GGGACCTCGG TGGAGCTTGG 
TTTACAACAG GGAATAGGTT TACACAAAGC ATTGTCCACA GGGCTGGACT ACTCCCCGCC 
CAGCGCTCCC AGGTCTGTCC CCGTGGCCAC CACGCTGCCT GCCGCGTACG CCACCCCGCA 
GCCAGGGACC CCGGTGTCCC CCGTGCAGTA CGCTCACCTG CCGCACACCT TCCAGTTCAT 
TGGGTCCTCC CAATACAGTG GAACCTATGC CAGCTTCATC CCATCACAGC TGATCCCCCC 
AACCGCCAAC CCCGTCACCA GTGCAGTGGC CTCGGCCGCA GGGGCCACCA CTCCATCCCA 
GCGCTCCCAG CTGGAGGCCT ATTCCACTCT GCTGGCCAAC ATGGGCAGTC TGAGCCAGAC 
GCCGGGACAC AAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001344786.1
CDS	1001..1558
Translation	MPASQEARDPRHQPVLRGEGPYPAQRQPPGGGHSMAPGQPWWPGPRGREAWAGRDLGGAWFTTGNRFTQSIVHRAGLLPAQRSQVCPRGHHAACRVRHPAARDPGVPRAVRSPAAHLPVHWVLPIQWNLCQLHPITADPPNRQPRHQCSGLGRRGHHSIPALPAGGLFHSAGQHGQSEPDAGTQG

Target ORF information:

RefSeq Version	NM_001357857.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001357857.1

ORF Insert Sequence:

ATGCCTGCCT CCCAAGAAGC GCGAGATCCC CGCCACCAGC CGGTCCTCCG AGGAGAAGGC 
CCCTACCCTG CCCAGCGACA ACCACCGGGT GGAGGGCACA GCATGGCTCC CGGGCAACCC 
TGGTGGCCGG GGCCACGGGG GCGGGAGGCA TGGGCCGGCA GGGACCTCGG TGGAGCTTGG 
TTTACAACAG GGAATAGGTT TACACAAAGC ATTGTCCACA GGGCTGGACT ACTCCCCGCC 
CAGCGCTCCC AGGTCTGTCC CCGTGGCCAC CACGCTGCCT GCCGCGTACG CCACCCCGCA 
GCCAGGGACC CCGGTGTCCC CCGTGCAGTA CGCTCACCTG CCGCACACCT TCCAGTTCAT 
TGGGTCCTCC CAATACAGTG GAACCTATGC CAGCTTCATC CCATCACAGC TGATCCCCCC 
AACCGCCAAC CCCGTCACCA GTGCAGTGGC CTCGGCCGCA GGGGCCACCA CTCCATCCCA 
GCGCTCCCAG CTGGAGGCCT ATTCCACTCT GCTGGCCAAC ATGGGCAGTC TGAGCCAGAC 
GCCGGGACAC AAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATXN1 ( NM_001357857.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001344786.1 Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu102879
Clone ID Related Accession (Same CDS sequence)	NM_001357857.1 , NM_001357857.2
Accession Version	NM_001357857.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	ataxin-1 Alt-ATXN1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011026.1, X79204.1 and AL009031.1. On Jun 2, 2019 this sequence version replaced NM_001357857.1. Transcript Variant: This variant (1) encodes multiple distinct proteins due to the use of alternative translation initiation codons. The longer, 815 aa protein represents the canonical protein, while a shorter 185 aa protein(Alt-ATXN1, PMID:23760502) that uses a different reading frame has also been described. Alt-ATXN1 does not share structural similarity to the ATXN1, but has been shown to interact with the ATXN1. This RefSeq represents the shorter protein, Alt-ATXN1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X79204.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: PMID: 23760502 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT CCCAAGAAGC GCGAGATCCC CGCCACCAGC CGGTCCTCCG AGGAGAAGGC 
CCCTACCCTG CCCAGCGACA ACCACCGGGT GGAGGGCACA GCATGGCTCC CGGGCAACCC 
TGGTGGCCGG GGCCACGGGG GCGGGAGGCA TGGGCCGGCA GGGACCTCGG TGGAGCTTGG 
TTTACAACAG GGAATAGGTT TACACAAAGC ATTGTCCACA GGGCTGGACT ACTCCCCGCC 
CAGCGCTCCC AGGTCTGTCC CCGTGGCCAC CACGCTGCCT GCCGCGTACG CCACCCCGCA 
GCCAGGGACC CCGGTGTCCC CCGTGCAGTA CGCTCACCTG CCGCACACCT TCCAGTTCAT 
TGGGTCCTCC CAATACAGTG GAACCTATGC CAGCTTCATC CCATCACAGC TGATCCCCCC 
AACCGCCAAC CCCGTCACCA GTGCAGTGGC CTCGGCCGCA GGGGCCACCA CTCCATCCCA 
GCGCTCCCAG CTGGAGGCCT ATTCCACTCT GCTGGCCAAC ATGGGCAGTC TGAGCCAGAC 
GCCGGGACAC AAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001344786.1
CDS	971..1528
Translation	MPASQEARDPRHQPVLRGEGPYPAQRQPPGGGHSMAPGQPWWPGPRGREAWAGRDLGGAWFTTGNRFTQSIVHRAGLLPAQRSQVCPRGHHAACRVRHPAARDPGVPRAVRSPAAHLPVHWVLPIQWNLCQLHPITADPPNRQPRHQCSGLGRRGHHSIPALPAGGLFHSAGQHGQSEPDAGTQG

Target ORF information:

RefSeq Version	NM_001357857.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ataxin 1 (ATXN1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001357857.2

ORF Insert Sequence:

ATGCCTGCCT CCCAAGAAGC GCGAGATCCC CGCCACCAGC CGGTCCTCCG AGGAGAAGGC 
CCCTACCCTG CCCAGCGACA ACCACCGGGT GGAGGGCACA GCATGGCTCC CGGGCAACCC 
TGGTGGCCGG GGCCACGGGG GCGGGAGGCA TGGGCCGGCA GGGACCTCGG TGGAGCTTGG 
TTTACAACAG GGAATAGGTT TACACAAAGC ATTGTCCACA GGGCTGGACT ACTCCCCGCC 
CAGCGCTCCC AGGTCTGTCC CCGTGGCCAC CACGCTGCCT GCCGCGTACG CCACCCCGCA 
GCCAGGGACC CCGGTGTCCC CCGTGCAGTA CGCTCACCTG CCGCACACCT TCCAGTTCAT 
TGGGTCCTCC CAATACAGTG GAACCTATGC CAGCTTCATC CCATCACAGC TGATCCCCCC 
AACCGCCAAC CCCGTCACCA GTGCAGTGGC CTCGGCCGCA GGGGCCACCA CTCCATCCCA 
GCGCTCCCAG CTGGAGGCCT ATTCCACTCT GCTGGCCAAC ATGGGCAGTC TGAGCCAGAC 
GCCGGGACAC AAGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATXN1 intermediate-length polyglutamine expansions are associated with amyotrophic lateral sclerosis.
Neurobiology of aging(2017 Nov)
Lattante S,Pomponi MG,Conte A,Marangi G,Bisogni G,Patanella AK,Meleo E,Lunetta C,Riva N,Mosca L,Carrera P,Bee M,Zollino M,Sabatelli M

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ATXN1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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