SAA1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SAA1
Entrez Gene ID	6288
Full Name	serum amyloid A1
Synonyms	PIG4,SAA,SAA2,TP53I4
General protein information	Preferred Names serum amyloid A1 Names serum amyloid A-1 protein serum amyloid A protein tumor protein p53 inducible protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.1
Summary	This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Feb 2016].
Disorder MIM:	104750

mRNA and Protein(s)

mRNA	Protein	Name
NM_199161.4	NP_954630.1	serum amyloid A-1 protein preproprotein
NM_000331.4	NP_000322.2	serum amyloid A-1 protein preproprotein
NM_000331.5	NP_000322.2	serum amyloid A-1 protein preproprotein
NM_001178006.2	NP_001171477.1	serum amyloid A-1 protein preproprotein
NM_199161.3	NP_954630.1	serum amyloid A-1 protein preproprotein
NM_001178006.1	NP_001171477.1	serum amyloid A-1 protein preproprotein
NM_199161.5	NP_954630.2	serum amyloid A-1 protein preproprotein

Pathways from BioSystems

Homologies

Homo sapiens (human)	SAA1	NP_000322.2
Bos taurus (cattle)	SAA3	NP_851359.2
Canis lupus familiaris (dog)	LOC100684663	XP_003432981.1
Mus musculus (house mouse)	Saa2	NP_035444.1
Canis lupus familiaris (dog)	LOC476879	XP_534081.1
Bos taurus (cattle)	SAA2	NP_001068728.1
Bos taurus (cattle)	M-SAA3.2	NP_001229502.1
Mus musculus (house mouse)	Saa1	NP_033143.1
Danio rerio (zebrafish)	saa	NP_001005599.1
Pan troglodytes (chimpanzee)	SAA1	XP_003951896.1
	SAA1	XP_001086366.1
	LOC694944	XP_001086477.1
Canis lupus familiaris (dog)	LOC102155886	XP_005633785.1

Gene Ontology
Bibliography

Related articles in PubMed

Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo.
Baranova IN, Souza ACP, Bocharov AV, Vishnyakova TG, Hu X, Vaisman BL, Amar MJ, Chen Z, Remaley AT, Patterson AP, Yuen PST, Star RA, Eggerman TL
PloS one12(4)e0175824(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The Serum amyloid A (SAA)/formyl peptide receptor-like 1 (FPRL1) contributed to pathogenesis of psoriasis by promoting keratinocyte proliferation and inflammation, thus providing a potential therapeutic target for disease therapy.
Title: Serum amyloid A, an acute phase protein, stimulates proliferative and proinflammatory responses of keratinocytes.

SR-A1 suppresses lung cancer metastasis by downregulating SAA1 production in tumor-associated macrophages (TAM).
Title: Scavenger Receptor A1 Prevents Metastasis of Non-Small Cell Lung Cancer via Suppression of Macrophage Serum Amyloid A1.

Serum amyloid A could represent a novel marker of primary unexplained recurrent early pregnancy loss because affected women exhibited elevated levels of this protein.
Title: Maternal serum amyloid A level as a novel marker of primary unexplained recurrent early pregnancy loss.

SAA, PROZ, and C4BPB may serve as new potential biomarkers for TB
Title: Serum amyloid A, protein Z, and C4b-binding protein ? chain as new potential biomarkers for pulmonary tuberculosis.

The findings identify SR-BII as a functional SAA receptor that mediates SAA uptake and contributes to its proinflammatory signaling via the MAPK-mediated signaling pathways.
Title: Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo.

The following SAA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SAA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20486	NM_000331.5 Latest version!	Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20486	NM_001178006.2 Latest version!	Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20486	NM_199161.4 Latest version!	Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu107354	NM_199161.5 Latest version!	Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu20486	NM_000331.4	Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20486	NM_199161.3	Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20486	NM_001178006.1	Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SAA1 ( NM_199161.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_954630.1 Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20486
Clone ID Related Accession (Same CDS sequence)	NM_199161.4 , NM_000331.4 , NM_000331.5 , NM_001178006.2 , NM_199161.3 , NM_001178006.1
Accession Version	NM_199161.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	serum amyloid A-1 protein preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG562565.1, BC007022.1, BX102362.1 and BE964588.2. On Feb 12, 2016 this sequence version replaced NM_199161.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG618566.1, BG562565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_954630.1
CDS	77..445
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_199161.4
Organism	Homo sapiens(human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199161.4

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SAA1 ( NM_000331.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000322.2 Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20486
Clone ID Related Accession (Same CDS sequence)	NM_199161.4 , NM_000331.4 , NM_000331.5 , NM_001178006.2 , NM_199161.3 , NM_001178006.1
Accession Version	NM_000331.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	serum amyloid A-1 protein preproprotein
Comment

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000322.2
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_000331.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000331.4

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SAA1 ( NM_000331.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000322.2 Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20486
Clone ID Related Accession (Same CDS sequence)	NM_199161.4 , NM_000331.4 , NM_000331.5 , NM_001178006.2 , NM_199161.3 , NM_001178006.1
Accession Version	NM_000331.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	serum amyloid A-1 protein preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG562565.1, BG565078.1, BX102362.1 and BE964588.2. This sequence is a reference standard in the RefSeqGene project. On Feb 12, 2016 this sequence version replaced NM_000331.4. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX102362.1, BG563257.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000322.2
CDS	224..592
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_000331.5
Organism	Homo sapiens(human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000331.5

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SAA1 ( NM_001178006.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171477.1 Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu20486
Clone ID Related Accession (Same CDS sequence)	NM_199161.4 , NM_000331.4 , NM_000331.5 , NM_001178006.2 , NM_199161.3 , NM_001178006.1
Accession Version	NM_001178006.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	serum amyloid A-1 protein preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG562565.1, BC105796.1, BX102362.1 and BE964588.2. On Feb 12, 2016 this sequence version replaced NM_001178006.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC105796.1, BG566837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171477.1
CDS	138..506
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_001178006.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001178006.2

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SAA1 ( NM_199161.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_954630.1 Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20486
Clone ID Related Accession (Same CDS sequence)	NM_199161.4 , NM_000331.4 , NM_000331.5 , NM_001178006.2 , NM_199161.3 , NM_001178006.1
Accession Version	NM_199161.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	serum amyloid A-1 protein preproprotein
Comment

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_954630.1
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_199161.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199161.3

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SAA1 ( NM_001178006.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171477.1 Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu20486
Clone ID Related Accession (Same CDS sequence)	NM_199161.4 , NM_000331.4 , NM_000331.5 , NM_001178006.2 , NM_199161.3 , NM_001178006.1
Accession Version	NM_001178006.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	serum amyloid A-1 protein preproprotein
Comment

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171477.1
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_001178006.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001178006.1

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAG CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SAA1 ( NM_199161.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_954630.2 Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.

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CloneID	OHu107354
Clone ID Related Accession (Same CDS sequence)	NM_199161.5
Accession Version	NM_199161.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	serum amyloid A-1 protein preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107948.7. On Nov 23, 2018 this sequence version replaced NM_199161.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX490424.1, SRR5189664.126194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000356524.9/ ENSP00000348918.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAC CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_954630.2
CDS	38..406
Translation	MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEVITDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY

Target ORF information:

RefSeq Version	NM_199161.5
Organism	Homo sapiens(human)
Definition	Homo sapiens serum amyloid A1 (SAA1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199161.5

ORF Insert Sequence:

ATGAAGCTTC TCACGGGCCT GGTTTTCTGC TCCTTGGTCC TGGGTGTCAG CAGCCGAAGC 
TTCTTTTCGT TCCTTGGCGA GGCTTTTGAT GGGGCTCGGG ACATGTGGAG AGCCTACTCT 
GACATGAGAG AAGCCAATTA CATCGGCTCA GACAAATACT TCCATGCTCG GGGGAACTAT 
GATGCTGCCA AAAGGGGACC TGGGGGTGCC TGGGCTGCAG AAGTGATCAC CGATGCCAGA 
GAGAATATCC AGAGATTCTT TGGCCATGGT GCGGAGGACT CGCTGGCTGA TCAGGCTGCC 
AATGAATGGG GCAGGAGTGG CAAAGACCCC AATCACTTCC GACCTGCTGG CCTGCCTGAG 
AAATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo.
PloS one12(4)e0175824(2017)
Baranova IN,Souza ACP,Bocharov AV,Vishnyakova TG,Hu X,Vaisman BL,Amar MJ,Chen Z,Remaley AT,Patterson AP,Yuen PST,Star RA,Eggerman TL

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SAA1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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