S100A5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	S100A5
Entrez Gene ID	6276
Full Name	S100 calcium binding protein A5
Synonyms	S100D
General protein information	Preferred Names S100 calcium binding protein A5 Names protein S100-A5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008].
Disorder MIM:	176991

mRNA and Protein(s)

mRNA	Protein	Name
NM_002962.1	NP_002953.2	protein S100-A5
XM_017002030.1	XP_016857519.1	protein S100-A5 isoform X2
XM_017002032.1	XP_016857521.1	protein S100-A5 isoform X4
XM_017002029.1	XP_016857518.1	protein S100-A5 isoform X1
XM_017002031.1	XP_016857520.1	protein S100-A5 isoform X4
XM_011509860.2	XP_011508162.1	protein S100-A5 isoform X3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	S100A5	XP_001138899.2
Canis lupus familiaris (dog)	S100A5	XP_005622881.1
Rattus norvegicus (Norway rat)	S100a5	NP_001099908.1
Bos taurus (cattle)	S100A5	NP_001179144.1
Homo sapiens (human)	S100A5	NP_002953.2
	LOC718270	XP_001110702.2
Mus musculus (house mouse)	S100a5	NP_035442.1

Gene Ontology
Bibliography

Related articles in PubMed

Conservation of Specificity in Two Low-Specificity Proteins.
Wheeler LC, Anderson JA, Morrison AJ, Wong CE, Harms MJ
Biochemistry(2017 Dec)

Biophysical characterization of Ca
Kim I, Lee KO, Yun YJ, Jeong JY, Kim EH, Cheong H, Ryu KS, Kim NK, Suh JY
Biochemical and biophysical research communications483(1)332-338(2017 01)

Pentamidine blocks the interaction between mutant S100A5 and RAGE V domain and inhibits the RAGE signaling pathway.
Cho CC, Chou RH, Yu C
Biochemical and biophysical research communications477(2)188-94(2016 08)

Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states.
Bertini I, Das Gupta S, Hu X, Karavelas T, Luchinat C, Parigi G, Yuan J
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry14(7)1097-107(2009 Sep)

Differential expression of S100 proteins in the developing human hippocampus and temporal cortex.
Chan WY, Xia CL, Dong DC, Heizmann CW, Yew DT
Microscopy research and technique60(6)600-13(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

S100A5 employs the periphery of the dimer interface to interact with RAGE-v
Title: Biophysical characterization of Ca

These results indicated that pentamidine blocks the binding between S100A5 and RAGE V domain. This finding is useful for the development of new anti-proliferation drugs.
Title: Pentamidine blocks the interaction between mutant S100A5 and RAGE V domain and inhibits the RAGE signaling pathway.

Homodimeric solution structures of S100A5 in both apo & Ca(II)-loaded forms were obtained & show conformational rearrangement on Ca binding. Also, large mobility was observed in hinge loop of apo-S100A5; this mobility was not quenched in Ca form.
Title: Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states.

Observational study of gene-disease association. (HuGE Navigator)
Title: Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.

Strongly expressed at 12 weeks gestation in the cells and fibers of the hippocampus, and then decreased with age. In the temporal cortex, detected from 12 weeks onwards, peaked at 20 to 24 weeks, and then decreased with age.
Title: Differential expression of S100 proteins in the developing human hippocampus and temporal cortex.

The following S100A5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S100A5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55744	NM_002962.1 Latest version!	Homo sapiens S100 calcium binding protein A5 (S100A5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu55744	XM_017002031.1 Latest version!	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu55744	XM_017002032.1 Latest version!	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu60345	XM_011509860.2 Latest version!	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu90370	XM_017002030.1 Latest version!	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu90369	XM_017002029.1 Latest version!	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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2-4 Clone	40% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

S100A5 ( NM_002962.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_002953.2 Homo sapiens S100 calcium binding protein A5 (S100A5), mRNA.

Price & Availability↑

CloneID	OHu55744
Clone ID Related Accession (Same CDS sequence)	NM_002962.1 , XM_017002032.1 , XM_017002031.1
Accession Version	NM_002962.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	protein S100-A5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z18954.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z18954.1, BC093955.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145240, SAMEA2145313 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGACTC CTCTGGAGAA GGCCCTGACC ACTATGGTGA CCACGTTTCA CAAATATTCG 
GGGAGAGAGG GTAGCAAACT GACCCTGAGT AGGAAGGAAC TCAAGGAGCT GATCAAGAAA 
GAGCTGTGTC TTGGGGAGAT GAAGGAGAGC AGCATCGATG ACTTGATGAA GAGCCTGGAC 
AAGAACAGCG ACCAGGAGAT CGACTTCAAG GAGTACTCGG TGTTCCTGAC CATGCTGTGC 
ATGGCCTACA ACGACTTCTT TCTAGAGGAC AACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002953.2
CDS	283..561
Translation	METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK

Target ORF information:

RefSeq Version	NM_002962.1
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein A5 (S100A5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002962.1

ORF Insert Sequence:

ATGGAGACTC CTCTGGAGAA GGCCCTGACC ACTATGGTGA CCACGTTTCA CAAATATTCG 
GGGAGAGAGG GTAGCAAACT GACCCTGAGT AGGAAGGAAC TCAAGGAGCT GATCAAGAAA 
GAGCTGTGTC TTGGGGAGAT GAAGGAGAGC AGCATCGATG ACTTGATGAA GAGCCTGGAC 
AAGAACAGCG ACCAGGAGAT CGACTTCAAG GAGTACTCGG TGTTCCTGAC CATGCTGTGC 
ATGGCCTACA ACGACTTCTT TCTAGAGGAC AACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100A5 ( XM_017002032.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857521.1 Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu55744
Clone ID Related Accession (Same CDS sequence)	NM_002962.1 , XM_017002032.1 , XM_017002031.1
Accession Version	XM_017002032.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein S100-A5 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACTC CTCTGGAGAA GGCCCTGACC ACTATGGTGA CCACGTTTCA CAAATATTCG 
GGGAGAGAGG GTAGCAAACT GACCCTGAGT AGGAAGGAAC TCAAGGAGCT GATCAAGAAA 
GAGCTGTGTC TTGGGGAGAT GAAGGAGAGC AGCATCGATG ACTTGATGAA GAGCCTGGAC 
AAGAACAGCG ACCAGGAGAT CGACTTCAAG GAGTACTCGG TGTTCCTGAC CATGCTGTGC 
ATGGCCTACA ACGACTTCTT TCTAGAGGAC AACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857521.1
CDS	902..1180
Translation	METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK

Target ORF information:

RefSeq Version	XM_017002032.1
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017002032.1

ORF Insert Sequence:

ATGGAGACTC CTCTGGAGAA GGCCCTGACC ACTATGGTGA CCACGTTTCA CAAATATTCG 
GGGAGAGAGG GTAGCAAACT GACCCTGAGT AGGAAGGAAC TCAAGGAGCT GATCAAGAAA 
GAGCTGTGTC TTGGGGAGAT GAAGGAGAGC AGCATCGATG ACTTGATGAA GAGCCTGGAC 
AAGAACAGCG ACCAGGAGAT CGACTTCAAG GAGTACTCGG TGTTCCTGAC CATGCTGTGC 
ATGGCCTACA ACGACTTCTT TCTAGAGGAC AACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100A5 ( XM_017002031.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857520.1 Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu55744
Clone ID Related Accession (Same CDS sequence)	NM_002962.1 , XM_017002032.1 , XM_017002031.1
Accession Version	XM_017002031.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein S100-A5 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACTC CTCTGGAGAA GGCCCTGACC ACTATGGTGA CCACGTTTCA CAAATATTCG 
GGGAGAGAGG GTAGCAAACT GACCCTGAGT AGGAAGGAAC TCAAGGAGCT GATCAAGAAA 
GAGCTGTGTC TTGGGGAGAT GAAGGAGAGC AGCATCGATG ACTTGATGAA GAGCCTGGAC 
AAGAACAGCG ACCAGGAGAT CGACTTCAAG GAGTACTCGG TGTTCCTGAC CATGCTGTGC 
ATGGCCTACA ACGACTTCTT TCTAGAGGAC AACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857520.1
CDS	1019..1297
Translation	METPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK

Target ORF information:

RefSeq Version	XM_017002031.1
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017002031.1

ORF Insert Sequence:

ATGGAGACTC CTCTGGAGAA GGCCCTGACC ACTATGGTGA CCACGTTTCA CAAATATTCG 
GGGAGAGAGG GTAGCAAACT GACCCTGAGT AGGAAGGAAC TCAAGGAGCT GATCAAGAAA 
GAGCTGTGTC TTGGGGAGAT GAAGGAGAGC AGCATCGATG ACTTGATGAA GAGCCTGGAC 
AAGAACAGCG ACCAGGAGAT CGACTTCAAG GAGTACTCGG TGTTCCTGAC CATGCTGTGC 
ATGGCCTACA ACGACTTCTT TCTAGAGGAC AACAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100A5 ( XM_011509860.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508162.1 Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu60345
Clone ID Related Accession (Same CDS sequence)	XM_011509860.2
Accession Version	XM_011509860.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein S100-A5 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509860.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGACACT CCTCGATATC AGAGCTGCAC ACTGTGATGG AGACTCCTCT GGAGAAGGCC 
CTGACCACTA TGGTGACCAC GTTTCACAAA TATTCGGGGA GAGAGGGTAG CAAACTGACC 
CTGAGTAGGA AGGAACTCAA GGAGCTGATC AAGAAAGAGC TGTGTCTTGG GGAGATGAAG 
GAGAGCAGCA TCGATGACTT GATGAAGAGC CTGGACAAGA ACAGCGACCA GGAGATCGAC 
TTCAAGGAGT ACTCGGTGTT CCTGACCATG CTGTGCATGG CCTACAACGA CTTCTTTCTA 
GAGGACAACA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508162.1
CDS	737..1051
Translation	MGHSSISELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK

Target ORF information:

RefSeq Version	XM_011509860.2
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509860.2

ORF Insert Sequence:

ATGGGACACT CCTCGATATC AGAGCTGCAC ACTGTGATGG AGACTCCTCT GGAGAAGGCC 
CTGACCACTA TGGTGACCAC GTTTCACAAA TATTCGGGGA GAGAGGGTAG CAAACTGACC 
CTGAGTAGGA AGGAACTCAA GGAGCTGATC AAGAAAGAGC TGTGTCTTGG GGAGATGAAG 
GAGAGCAGCA TCGATGACTT GATGAAGAGC CTGGACAAGA ACAGCGACCA GGAGATCGAC 
TTCAAGGAGT ACTCGGTGTT CCTGACCATG CTGTGCATGG CCTACAACGA CTTCTTTCTA 
GAGGACAACA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100A5 ( XM_017002030.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857519.1 Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu90370
Clone ID Related Accession (Same CDS sequence)	XM_017002030.1
Accession Version	XM_017002030.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 333bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein S100-A5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGCTG CTTGGATTCT CTGGGCTCAC TCCCACAGTG AGCTGCACAC TGTGATGGAG 
ACTCCTCTGG AGAAGGCCCT GACCACTATG GTGACCACGT TTCACAAATA TTCGGGGAGA 
GAGGGTAGCA AACTGACCCT GAGTAGGAAG GAACTCAAGG AGCTGATCAA GAAAGAGCTG 
TGTCTTGGGG AGATGAAGGA GAGCAGCATC GATGACTTGA TGAAGAGCCT GGACAAGAAC 
AGCGACCAGG AGATCGACTT CAAGGAGTAC TCGGTGTTCC TGACCATGCT GTGCATGGCC 
TACAACGACT TCTTTCTAGA GGACAACAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857519.1
CDS	652..984
Translation	MPAAWILWAHSHSELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK

Target ORF information:

RefSeq Version	XM_017002030.1
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017002030.1

ORF Insert Sequence:

ATGCCTGCTG CTTGGATTCT CTGGGCTCAC TCCCACAGTG AGCTGCACAC TGTGATGGAG 
ACTCCTCTGG AGAAGGCCCT GACCACTATG GTGACCACGT TTCACAAATA TTCGGGGAGA 
GAGGGTAGCA AACTGACCCT GAGTAGGAAG GAACTCAAGG AGCTGATCAA GAAAGAGCTG 
TGTCTTGGGG AGATGAAGGA GAGCAGCATC GATGACTTGA TGAAGAGCCT GGACAAGAAC 
AGCGACCAGG AGATCGACTT CAAGGAGTAC TCGGTGTTCC TGACCATGCT GTGCATGGCC 
TACAACGACT TCTTTCTAGA GGACAACAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100A5 ( XM_017002029.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857518.1 Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu90369
Clone ID Related Accession (Same CDS sequence)	XM_017002029.1
Accession Version	XM_017002029.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 402bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein S100-A5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGTTTG GGTGTCCTGG GAGGACAGAG ATCAGGGAAA TAAAGGCAGA AGGCAGTGAG 
AGGGAGGCTA TGCCTGCTGC TTGGATTCTC TGGGCTCACT CCCACAGTGA GCTGCACACT 
GTGATGGAGA CTCCTCTGGA GAAGGCCCTG ACCACTATGG TGACCACGTT TCACAAATAT 
TCGGGGAGAG AGGGTAGCAA ACTGACCCTG AGTAGGAAGG AACTCAAGGA GCTGATCAAG 
AAAGAGCTGT GTCTTGGGGA GATGAAGGAG AGCAGCATCG ATGACTTGAT GAAGAGCCTG 
GACAAGAACA GCGACCAGGA GATCGACTTC AAGGAGTACT CGGTGTTCCT GACCATGCTG 
TGCATGGCCT ACAACGACTT CTTTCTAGAG GACAACAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857518.1
CDS	254..655
Translation	MEFGCPGRTEIREIKAEGSEREAMPAAWILWAHSHSELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKKELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK

Target ORF information:

RefSeq Version	XM_017002029.1
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein A5 (S100A5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017002029.1

ORF Insert Sequence:

ATGGAGTTTG GGTGTCCTGG GAGGACAGAG ATCAGGGAAA TAAAGGCAGA AGGCAGTGAG 
AGGGAGGCTA TGCCTGCTGC TTGGATTCTC TGGGCTCACT CCCACAGTGA GCTGCACACT 
GTGATGGAGA CTCCTCTGGA GAAGGCCCTG ACCACTATGG TGACCACGTT TCACAAATAT 
TCGGGGAGAG AGGGTAGCAA ACTGACCCTG AGTAGGAAGG AACTCAAGGA GCTGATCAAG 
AAAGAGCTGT GTCTTGGGGA GATGAAGGAG AGCAGCATCG ATGACTTGAT GAAGAGCCTG 
GACAAGAACA GCGACCAGGA GATCGACTTC AAGGAGTACT CGGTGTTCCT GACCATGCTG 
TGCATGGCCT ACAACGACTT CTTTCTAGAG GACAACAAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Conservation of Specificity in Two Low-Specificity Proteins.
Biochemistry(2017 Dec)
Wheeler LC,Anderson JA,Morrison AJ,Wong CE,Harms MJ

Biophysical characterization of Ca
Biochemical and biophysical research communications483(1)332-338(2017 01)
Kim I,Lee KO,Yun YJ,Jeong JY,Kim EH,Cheong H,Ryu KS,Kim NK,Suh JY

Pentamidine blocks the interaction between mutant S100A5 and RAGE V domain and inhibits the RAGE signaling pathway.
Biochemical and biophysical research communications477(2)188-94(2016 08)
Cho CC,Chou RH,Yu C

Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry14(7)1097-107(2009 Sep)
Bertini I,Das Gupta S,Hu X,Karavelas T,Luchinat C,Parigi G,Yuan J

Differential expression of S100 proteins in the developing human hippocampus and temporal cortex.
Microscopy research and technique60(6)600-13(2003 Apr)
Chan WY,Xia CL,Dong DC,Heizmann CW,Yew DT

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S100A5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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