RSU1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RSU1
Entrez Gene ID	6251
Full Name	Ras suppressor protein 1
Synonyms	RSP-1
General protein information	Preferred Names Ras suppressor protein 1 Names ras suppressor protein 1 ras suppressor protein 1 variant 1 ras suppressor protein 1 variant 2 ras suppressor protein 1 variant 3 ras suppressor protein 1 variant 5 rsu-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10p13
Summary	This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008].
Disorder MIM:	179555

mRNA and Protein(s)

mRNA	Protein	Name
XM_005252552.3	XP_005252609.1	ras suppressor protein 1 isoform X1
NM_012425.3	NP_036557.1	ras suppressor protein 1 isoform 1
NM_012425.4	NP_036557.1	ras suppressor protein 1 isoform 1
NM_152724.2	NP_689937.2	ras suppressor protein 1 isoform 2
XM_005252552.4	XP_005252609.1	ras suppressor protein 1 isoform X1

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	rsu-1	NP_497716.1
Bos taurus (cattle)	RSU1	NP_001035691.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008785	XP_314913.2
Xenopus tropicalis (tropical clawed frog)	rsu1	NP_001015695.1
Homo sapiens (human)	RSU1	NP_036557.1
Pan troglodytes (chimpanzee)	RSU1	XP_001151460.1
Gallus gallus (chicken)	RSU1	NP_001186520.1
Danio rerio (zebrafish)	rsu1	XP_005174234.1
Canis lupus familiaris (dog)	RSU1	XP_535177.1
Mus musculus (house mouse)	Rsu1	NP_033131.2
Rattus norvegicus (Norway rat)	Rsu1	NP_001102874.1
Drosophila melanogaster (fruit fly)	ics	NP_609665.2

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

MicroRNA-409-5p is upregulated in breast cancer and its downregulation inhibits cancer development through downstream target of RSU1.
Yu H, Xing H, Han W, Wang Y, Qi T, Song C, Xu Z, Li H, Huang Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(5)1010428317701647(2017 May)

Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach.
Gkretsi V, Stylianou A, Louca M, Stylianopoulos T
Oncotarget8(16)27364-27379(2017 Apr)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ras suppressor protein 1 was confirmed to be directly targeted by miR-409-5p in breast cancer cells. Small interfering RNA-mediated Ras suppressor protein 1 inhibition reversely promoted cancer proliferation and migration in miR-409-5p-downregualted breast cancer cells. MiR-409-5p is downregulated in breast cancer and its inhibition has anti-cancer effect on breast cancer development both in vitro and in vivo.
Title: MicroRNA-409-5p is upregulated in breast cancer and its downregulation inhibits cancer development through downstream target of RSU1.

integrin/Rsu1/Rac1/actin signaling has a conserved role in modulating reward-related phenotypes, including ethanol consumption, across phyla
Title: Rsu1 regulates ethanol consumption in Drosophila and humans.

results showed that RSU-1 expression is elevated in HepG2 cells both at the mRNA and protein level
Title: Elimination of Ras Suppressor-1 from hepatocellular carcinoma cells hinders their in vitro metastatic properties.

Upregulation of RSU1 is associated with metastatic breast cancer.
Title: Ras suppressor-1 promotes apoptosis in breast cancer cells by inhibiting PINCH-1 and activating p53-upregulated-modulator of apoptosis (PUMA); verification from metastatic breast cancer human samples.

Rsu1 is required for EGF-induced activation of the p38 map kinase signaling
Title: Rsu1 contributes to cell adhesion and spreading in MCF10A cells via effects on P38 map kinase signaling.

The following RSU1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RSU1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06227	NM_012425.4 Latest version!	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu06898	NM_152724.2 Latest version!	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu43836	XM_005252552.4 Latest version!	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu06227	NM_012425.3	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu43836	XM_005252552.3	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RSU1 ( NM_012425.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036557.1 Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06227
Clone ID Related Accession (Same CDS sequence)	NM_012425.3 , NM_012425.4
Accession Version	NM_012425.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	ras suppressor protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG400752.1, BC005993.1, BX647733.1 and AK055596.1. On Sep 11, 2003 this sequence version replaced NM_012425.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.138915.1, SRR1803613.29414.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGGA 
AACTTGGATT TAACTGGCCA GAAGCAGGTA TTCAAAGCAG AGAACAATCC CTGGGTGACC 
CCCATTGCAG ACCAGTTCCA GCTTGGCGTG TCCCATGTTT TTGAGTATAT CCGTTCTGAG 
ACATACAAAT ACCTCTACGG CAGACACATG CAGGCCAACC CAGAACCACC GAAGAAGAAT 
AATGACAAAT CGAAAAAGAT CAGCCGGAAA CCCCTGGCAG CCAAGAACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036557.1
CDS	144..977
Translation	MSKSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKNR

Target ORF information:

RefSeq Version	NM_012425.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012425.3

ORF Insert Sequence:

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGGA 
AACTTGGATT TAACTGGCCA GAAGCAGGTA TTCAAAGCAG AGAACAATCC CTGGGTGACC 
CCCATTGCAG ACCAGTTCCA GCTTGGCGTG TCCCATGTTT TTGAGTATAT CCGTTCTGAG 
ACATACAAAT ACCTCTACGG CAGACACATG CAGGCCAACC CAGAACCACC GAAGAAGAAT 
AATGACAAAT CGAAAAAGAT CAGCCGGAAA CCCCTGGCAG CCAAGAACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RSU1 ( NM_012425.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036557.1 Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06227
Clone ID Related Accession (Same CDS sequence)	NM_012425.3 , NM_012425.4
Accession Version	NM_012425.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	ras suppressor protein 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG400752.1, BC005993.1, BX647733.1, AK055596.1 and AC073367.11. On Nov 22, 2018 this sequence version replaced NM_012425.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.245998.1, SRR1803613.241393.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000345264.10/ ENSP00000339521.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGGA 
AACTTGGATT TAACTGGCCA GAAGCAGGTA TTCAAAGCAG AGAACAATCC CTGGGTGACC 
CCCATTGCAG ACCAGTTCCA GCTTGGCGTG TCCCATGTTT TTGAGTATAT CCGTTCTGAG 
ACATACAAAT ACCTCTACGG CAGACACATG CAGGCCAACC CAGAACCACC GAAGAAGAAT 
AATGACAAAT CGAAAAAGAT CAGCCGGAAA CCCCTGGCAG CCAAGAACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036557.1
CDS	114..947
Translation	MSKSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKNR

Target ORF information:

RefSeq Version	NM_012425.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012425.4

ORF Insert Sequence:

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGGA 
AACTTGGATT TAACTGGCCA GAAGCAGGTA TTCAAAGCAG AGAACAATCC CTGGGTGACC 
CCCATTGCAG ACCAGTTCCA GCTTGGCGTG TCCCATGTTT TTGAGTATAT CCGTTCTGAG 
ACATACAAAT ACCTCTACGG CAGACACATG CAGGCCAACC CAGAACCACC GAAGAAGAAT 
AATGACAAAT CGAAAAAGAT CAGCCGGAAA CCCCTGGCAG CCAAGAACAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RSU1 ( NM_152724.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_689937.2 Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06898
Clone ID Related Accession (Same CDS sequence)	NM_152724.2
Accession Version	NM_152724.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	ras suppressor protein 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG400752.1, BX647733.1 and AK055596.1. On Sep 11, 2003 this sequence version replaced NM_152724.1. Transcript Variant: This variant (2) lacks an alternate in-frame segment in the 5' UTR and 5' coding region and uses a downstream start codon, compared to variant 1. It encodes isoform 2 which has a shorter N-terminus, compared to isoform 1. This transcript is supported by multiple ESTs, but the predicted ORF has not yet been experimentally confirmed. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX647733.1, SRR1803611.190266.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGTGCCAC CGAACATCGC AGAACTGAAG AATTTGGAGG TGCTCAACTT TTTTAATAAC 
CAAATCGAGG AGCTGCCCAC ACAGATCAGT AGCCTTCAGA AACTCAAACA CCTGAACCTT 
GGCATGAACA GGCTGAACAC TTTGCCACGA GGCTTCGGCT CCCTGCCAGC TCTTGAGGTT 
CTGGACTTGA CGTACAACAA CTTGAGCGAA AATTCTCTTC CTGGAAACTT CTTCTACCTG 
ACCACCCTGC GTGCACTCTA TCTAAGTGAC AACGATTTTG AAATCCTGCC GCCAGATATT 
GGGAAGCTCA CAAAGTTGCA GATACTCAGC CTTAGGGATA ACGACCTGAT CTCGCTGCCT 
AAGGAAATCG GGGAGCTTAC CCAGCTTAAA GAGCTCCACA TTCAGGGGAA CCGCCTCACC 
GTTCTGCCCC CAGAACTAGG AAACTTGGAT TTAACTGGCC AGAAGCAGGT ATTCAAAGCA 
GAGAACAATC CCTGGGTGAC CCCCATTGCA GACCAGTTCC AGCTTGGCGT GTCCCATGTT 
TTTGAGTATA TCCGTTCTGA GACATACAAA TACCTCTACG GCAGACACAT GCAGGCCAAC 
CCAGAACCAC CGAAGAAGAA TAATGACAAA TCGAAAAAGA TCAGCCGGAA ACCCCTGGCA 
GCCAAGAACA GATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689937.2
CDS	191..865
Translation	MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELGNLDLTGQKQVFKAENNPWVTPIADQFQLGVSHVFEYIRSETYKYLYGRHMQANPEPPKKNNDKSKKISRKPLAAKNR

Target ORF information:

RefSeq Version	NM_152724.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152724.2

ORF Insert Sequence:

ATGGTGCCAC CGAACATCGC AGAACTGAAG AATTTGGAGG TGCTCAACTT TTTTAATAAC 
CAAATCGAGG AGCTGCCCAC ACAGATCAGT AGCCTTCAGA AACTCAAACA CCTGAACCTT 
GGCATGAACA GGCTGAACAC TTTGCCACGA GGCTTCGGCT CCCTGCCAGC TCTTGAGGTT 
CTGGACTTGA CGTACAACAA CTTGAGCGAA AATTCTCTTC CTGGAAACTT CTTCTACCTG 
ACCACCCTGC GTGCACTCTA TCTAAGTGAC AACGATTTTG AAATCCTGCC GCCAGATATT 
GGGAAGCTCA CAAAGTTGCA GATACTCAGC CTTAGGGATA ACGACCTGAT CTCGCTGCCT 
AAGGAAATCG GGGAGCTTAC CCAGCTTAAA GAGCTCCACA TTCAGGGGAA CCGCCTCACC 
GTTCTGCCCC CAGAACTAGG AAACTTGGAT TTAACTGGCC AGAAGCAGGT ATTCAAAGCA 
GAGAACAATC CCTGGGTGAC CCCCATTGCA GACCAGTTCC AGCTTGGCGT GTCCCATGTT 
TTTGAGTATA TCCGTTCTGA GACATACAAA TACCTCTACG GCAGACACAT GCAGGCCAAC 
CCAGAACCAC CGAAGAAGAA TAATGACAAA TCGAAAAAGA TCAGCCGGAA ACCCCTGGCA 
GCCAAGAACA GATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RSU1 ( XM_005252552.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005252609.1 Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43836
Clone ID Related Accession (Same CDS sequence)	XM_005252552.3 , XM_005252552.4
Accession Version	XM_005252552.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ras suppressor protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005252552.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGCC 
TCTACGGCAG ACACATGCAG GCCAACCCAG AACCACCGAA GAAGAATAAT GACAAATCGA 
AAAAGATCAG CCGGAAACCC CTGGCAGCCA AGAACAGATA AGGAAGGGAT TGGCATCGGC 
TGGCCTTCCA GCACCTTCTC TCTCCAACAC TTCATTCTCT CTTGCCCTGT CTCTCAAATA 
AACCCAATGC TGCGTGTGAG GCCTTTTTTA TTTTTCTTTT CACTCTCTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005252609.1
CDS	227..1060
Translation	MSKSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELASTADTCRPTQNHRRRIMTNRKRSAGNPWQPRTDKEGIGIGWPSSTFSLQHFILSCPVSQINPMLRVRPFLFFFSLSF

Target ORF information:

RefSeq Version	XM_005252552.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005252552.3

ORF Insert Sequence:

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGCC 
TCTACGGCAG ACACATGCAG GCCAACCCAG AACCACCGAA GAAGAATAAT GACAAATCGA 
AAAAGATCAG CCGGAAACCC CTGGCAGCCA AGAACAGATA AGGAAGGGAT TGGCATCGGC 
TGGCCTTCCA GCACCTTCTC TCTCCAACAC TTCATTCTCT CTTGCCCTGT CTCTCAAATA 
AACCCAATGC TGCGTGTGAG GCCTTTTTTA TTTTTCTTTT CACTCTCTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RSU1 ( XM_005252552.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005252609.1 Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43836
Clone ID Related Accession (Same CDS sequence)	XM_005252552.3 , XM_005252552.4
Accession Version	XM_005252552.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ras suppressor protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005252552.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGCC 
TCTACGGCAG ACACATGCAG GCCAACCCAG AACCACCGAA GAAGAATAAT GACAAATCGA 
AAAAGATCAG CCGGAAACCC CTGGCAGCCA AGAACAGATA AGGAAGGGAT TGGCATCGGC 
TGGCCTTCCA GCACCTTCTC TCTCCAACAC TTCATTCTCT CTTGCCCTGT CTCTCAAATA 
AACCCAATGC TGCGTGTGAG GCCTTTTTTA TTTTTCTTTT CACTCTCTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005252609.1
CDS	141..974
Translation	MSKSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVLPPELASTADTCRPTQNHRRRIMTNRKRSAGNPWQPRTDKEGIGIGWPSSTFSLQHFILSCPVSQINPMLRVRPFLFFFSLSF

Target ORF information:

RefSeq Version	XM_005252552.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Ras suppressor protein 1 (RSU1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005252552.4

ORF Insert Sequence:

ATGTCCAAGT CTCTGAAGAA GTTGGTGGAG GAGAGCCGGG AGAAGAACCA GCCCGAGGTG 
GACATGAGTG ACCGGGGCAT CTCCAACATG CTGGATGTCA ACGGCCTCTT TACCTTATCC 
CATATCACAC AACTGGTCCT CAGCCATAAC AAGCTAACAA TGGTGCCACC GAACATCGCA 
GAACTGAAGA ATTTGGAGGT GCTCAACTTT TTTAATAACC AAATCGAGGA GCTGCCCACA 
CAGATCAGTA GCCTTCAGAA ACTCAAACAC CTGAACCTTG GCATGAACAG GCTGAACACT 
TTGCCACGAG GCTTCGGCTC CCTGCCAGCT CTTGAGGTTC TGGACTTGAC GTACAACAAC 
TTGAGCGAAA ATTCTCTTCC TGGAAACTTC TTCTACCTGA CCACCCTGCG TGCACTCTAT 
CTAAGTGACA ACGATTTTGA AATCCTGCCG CCAGATATTG GGAAGCTCAC AAAGTTGCAG 
ATACTCAGCC TTAGGGATAA CGACCTGATC TCGCTGCCTA AGGAAATCGG GGAGCTTACC 
CAGCTTAAAG AGCTCCACAT TCAGGGGAAC CGCCTCACCG TTCTGCCCCC AGAACTAGCC 
TCTACGGCAG ACACATGCAG GCCAACCCAG AACCACCGAA GAAGAATAAT GACAAATCGA 
AAAAGATCAG CCGGAAACCC CTGGCAGCCA AGAACAGATA AGGAAGGGAT TGGCATCGGC 
TGGCCTTCCA GCACCTTCTC TCTCCAACAC TTCATTCTCT CTTGCCCTGT CTCTCAAATA 
AACCCAATGC TGCGTGTGAG GCCTTTTTTA TTTTTCTTTT CACTCTCTTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

MicroRNA-409-5p is upregulated in breast cancer and its downregulation inhibits cancer development through downstream target of RSU1.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine39(5)1010428317701647(2017 May)
Yu H,Xing H,Han W,Wang Y,Qi T,Song C,Xu Z,Li H,Huang Y

Identification of Ras suppressor-1 (RSU-1) as a potential breast cancer metastasis biomarker using a three-dimensional in vitro approach.
Oncotarget8(16)27364-27379(2017 Apr)
Gkretsi V,Stylianou A,Louca M,Stylianopoulos T

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

RSU1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報