RPS27 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPS27
Entrez Gene ID	6232
Full Name	ribosomal protein S27
Synonyms	DBA17,MPS-1,MPS1,S27
General protein information	Preferred Names ribosomal protein S27 Names 40S ribosomal protein S27 metallopan-stimulin 1 metallopanstimulin 1 small ribosomal subunit protein eS27
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S27e family of ribosomal proteins and component of the 40S subunit. The encoded protein contains a C4-type zinc finger domain that can bind to zinc and may bind to nucleic acid. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. Mutations in this gene have been identified in numerous melanoma patients and in at least one patient with Diamond-Blackfan anemia (DBA). Elevated expression of this gene has been observed in various human cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017].
Disorder MIM:	603702
Disorder Html:	?Diamond-Blackfan anemia 17, 617409 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001349946.1	NP_001336875.1	40S ribosomal protein S27 isoform 2
NM_001030.5	NP_001021.1	40S ribosomal protein S27 isoform 1
NM_001030.4	NP_001021.1	40S ribosomal protein S27
NM_001349947.1	NP_001336876.1	40S ribosomal protein S27 isoform 2
NM_001030.6	NP_001021.1	40S ribosomal protein S27 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Rps27	NP_446049.1
Danio rerio (zebrafish)	rps27.2	NP_957059.1
Drosophila melanogaster (fruit fly)	RpS27	NP_651359.1
Caenorhabditis elegans (roundworm)	rps-27	NP_503134.1
Saccharomyces cerevisiae (baker's yeast)	RPS27B	NP_011885.1
Magnaporthe oryzae (rice blast fungus)	MGG_02872	XP_003720862.1
Pan troglodytes (chimpanzee)	LOC100614845	XP_003312546.1
Saccharomyces cerevisiae (baker's yeast)	RPS27A	NP_012766.1
Xenopus tropicalis (tropical clawed frog)	rps27	NP_001165123.1
Homo sapiens (human)	RPS27	NP_001021.1
Pan troglodytes (chimpanzee)	LOC452745	XP_509802.2
Danio rerio (zebrafish)	rps27.1	NP_001153000.1
Kluyveromyces lactis	KLLA0E11661g	XP_454477.1
Schizosaccharomyces pombe (fission yeast)	rps27	NP_595214.1
Arabidopsis thaliana (thale cress)	RS27A	NP_191670.1
Arabidopsis thaliana (thale cress)	AT3G61111	NP_001118871.1
Oryza sativa (rice)	Os02g0478700	NP_001046847.1
Oryza sativa (rice)	Os04g0346100	NP_001052512.1
Pan troglodytes (chimpanzee)	RPS27	NP_001238926.1
Bos taurus (cattle)	RPS27	NP_001091604.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007157	XP_308611.1
Arabidopsis thaliana (thale cress)	AT5G47930	NP_199604.1
Canis lupus familiaris (dog)	RPS27	NP_001239215.1
Eremothecium gossypii	AGOS_ACR065C	NP_983467.2
Neurospora crassa	NCU00618	XP_965758.1
Arabidopsis thaliana (thale cress)	AT2G45710	NP_182095.1

Gene Ontology
Bibliography

Related articles in PubMed

CFTR modulates RPS27 gene expression using chloride anion as signaling effector.
Valdivieso ?G, Mori C, Clauzure M, Massip-Copiz M, Santa-Coloma TA
Archives of biochemistry and biophysics633103-109(2017 Nov)

Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation.
Maciejowski J, Drechsler H, Grundner-Culemann K, Ballister ER, Rodriguez-Rodriguez JA, Rodriguez-Bravo V, Jones MJK, Foley E, Lampson MA, Daub H, McAinsh AD, Jallepalli PV
Developmental cell41(2)143-156.e6(2017 04)

A Novel Marker for Purkinje Cells, Ribosomal Protein MPS1/S27: Expression of MPS1 in Human Cerebellum.
Fernandez-Pol JA
Cancer genomics & proteomics13(1)47-53(2016 Jan-Feb)

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.
Wang R, Yoshida K, Toki T, Sawada T, Uechi T, Okuno Y, Sato-Otsubo A, Kudo K, Kamimaki I, Kanezaki R, Shiraishi Y, Chiba K, Tanaka H, Terui K, Sato T, Iribe Y, Ohga S, Kuramitsu M, Hamaguchi I, Ohara A, Hara J, Goi K, Matsubara K, Koike K, Ishiguro A, Okamoto Y, Watanabe K, Kanno H, Kojima S, Miyano S, Kenmochi N, Ogawa S, Ito E
British journal of haematology168(6)854-64(2015 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Chloride anion behaves as a signaling effector for CFTR in the modulation of RPS27 expression.
Title: CFTR modulates RPS27 gene expression using chloride anion as signaling effector.

reveal how Mps1 dynamically modifies kinetochores to correct improper attachments and ensure faithful chromosome segregation
Title: Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation.

MPS1 is a new marker of Purkinje Cells.
Title: A Novel Marker for Purkinje Cells, Ribosomal Protein MPS1/S27: Expression of MPS1 in Human Cerebellum.

Loss of function mutations in RPL27 and RPS27 lead to Diamond-Blackfan anaemia.
Title: Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.

We identified frequent recurrent (i.e. hotspot) mutation in the 5' untranslated region of RPS27 in ~10% of melanoma samples
Title: A highly recurrent RPS27 5'UTR mutation in melanoma.

The following RPS27 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS27 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30759	NM_001030.6 Latest version!	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu101190	NM_001349947.1 Latest version!	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu101190	NM_001349946.1 Latest version!	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu30759	NM_001030.4	Homo sapiens ribosomal protein S27 (RPS27), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30759	NM_001030.5	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPS27 ( NM_001030.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001021.1 Homo sapiens ribosomal protein S27 (RPS27), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30759
Clone ID Related Accession (Same CDS sequence)	NM_001030.5 , NM_001030.4 , NM_001030.6
Accession Version	NM_001030.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	40S ribosomal protein S27 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Karyn Megy, Francesco Amaldi. The reference sequence was derived from CD175039.1, BC070219.1, D28454.1 and AJ572583.1. This sequence is a reference standard in the RefSeqGene project. On Mar 30, 2017 this sequence version replaced NM_001030.4. Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU958995.1, BQ276551.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCTCTCG CAAAGGATCT CCTTCATCCC TCTCCAGAAG AGGAGAAGAG GAAACACAAG 
AAGAAACGCC TGGTGCAGAG CCCCAATTCC TACTTCATGG ATGTGAAATG CCCAGGATGC 
TATAAAATCA CCACGGTCTT TAGCCATGCA CAAACGGTAG TTTTGTGTGT TGGCTGCTCC 
ACTGTCCTCT GCCAGCCTAC AGGAGGAAAA GCAAGGCTTA CAGAAGGATG TTCCTTCAGG 
AGGAAGCAGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001021.1
CDS	43..297
Translation	MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Target ORF information:

RefSeq Version	NM_001030.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030.5

ORF Insert Sequence:

ATGCCTCTCG CAAAGGATCT CCTTCATCCC TCTCCAGAAG AGGAGAAGAG GAAACACAAG 
AAGAAACGCC TGGTGCAGAG CCCCAATTCC TACTTCATGG ATGTGAAATG CCCAGGATGC 
TATAAAATCA CCACGGTCTT TAGCCATGCA CAAACGGTAG TTTTGTGTGT TGGCTGCTCC 
ACTGTCCTCT GCCAGCCTAC AGGAGGAAAA GCAAGGCTTA CAGAAGGATG TTCCTTCAGG 
AGGAAGCAGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS27 ( NM_001030.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001021.1 Homo sapiens ribosomal protein S27 (RPS27), mRNA.

Price & Availability↑

CloneID	OHu30759
Clone ID Related Accession (Same CDS sequence)	NM_001030.5 , NM_001030.4 , NM_001030.6
Accession Version	NM_001030.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	40S ribosomal protein S27
Comment

ATGCCTCTCG CAAAGGATCT CCTTCATCCC TCTCCAGAAG AGGAGAAGAG GAAACACAAG 
AAGAAACGCC TGGTGCAGAG CCCCAATTCC TACTTCATGG ATGTGAAATG CCCAGGATGC 
TATAAAATCA CCACGGTCTT TAGCCATGCA CAAACGGTAG TTTTGTGTGT TGGCTGCTCC 
ACTGTCCTCT GCCAGCCTAC AGGAGGAAAA GCAAGGCTTA CAGAAGGATG TTCCTTCAGG 
AGGAAGCAGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001021.1
Translation	MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Target ORF information:

RefSeq Version	NM_001030.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens ribosomal protein S27 (RPS27), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030.4

ORF Insert Sequence:

ATGCCTCTCG CAAAGGATCT CCTTCATCCC TCTCCAGAAG AGGAGAAGAG GAAACACAAG 
AAGAAACGCC TGGTGCAGAG CCCCAATTCC TACTTCATGG ATGTGAAATG CCCAGGATGC 
TATAAAATCA CCACGGTCTT TAGCCATGCA CAAACGGTAG TTTTGTGTGT TGGCTGCTCC 
ACTGTCCTCT GCCAGCCTAC AGGAGGAAAA GCAAGGCTTA CAGAAGGATG TTCCTTCAGG 
AGGAAGCAGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS27 ( NM_001030.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_001021.1 Homo sapiens ribosomal protein S27 (RPS27), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30759
Clone ID Related Accession (Same CDS sequence)	NM_001030.5 , NM_001030.4 , NM_001030.6
Accession Version	NM_001030.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	40S ribosomal protein S27 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Karyn Megy, Francesco Amaldi. The reference sequence was derived from BC070219.1, D28454.1 and AJ572583.1. This sequence is a reference standard in the RefSeqGene project. On May 21, 2018 this sequence version replaced NM_001030.5. Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU963235.1, CD520794.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000651669.1/ ENSP00000499044.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTCTCG CAAAGGATCT CCTTCATCCC TCTCCAGAAG AGGAGAAGAG GAAACACAAG 
AAGAAACGCC TGGTGCAGAG CCCCAATTCC TACTTCATGG ATGTGAAATG CCCAGGATGC 
TATAAAATCA CCACGGTCTT TAGCCATGCA CAAACGGTAG TTTTGTGTGT TGGCTGCTCC 
ACTGTCCTCT GCCAGCCTAC AGGAGGAAAA GCAAGGCTTA CAGAAGGATG TTCCTTCAGG 
AGGAAGCAGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001021.1
CDS	36..290
Translation	MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Target ORF information:

RefSeq Version	NM_001030.6
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030.6

ORF Insert Sequence:

ATGCCTCTCG CAAAGGATCT CCTTCATCCC TCTCCAGAAG AGGAGAAGAG GAAACACAAG 
AAGAAACGCC TGGTGCAGAG CCCCAATTCC TACTTCATGG ATGTGAAATG CCCAGGATGC 
TATAAAATCA CCACGGTCTT TAGCCATGCA CAAACGGTAG TTTTGTGTGT TGGCTGCTCC 
ACTGTCCTCT GCCAGCCTAC AGGAGGAAAA GCAAGGCTTA CAGAAGGATG TTCCTTCAGG 
AGGAAGCAGC ACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS27 ( NM_001349946.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336875.1 Homo sapiens ribosomal protein S27 (RPS27), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu101190
Clone ID Related Accession (Same CDS sequence)	NM_001349946.1 , NM_001349947.1
Accession Version	NM_001349946.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 159bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	40S ribosomal protein S27 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD175039.1, BC070219.1, CN270933.1 and AJ572583.1. Transcript Variant: This variant (2) includes an alternate exon in its 5' UTR and uses a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. Variants 2 and 3 encode the same isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD247477.1, CD250228.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121

ATGGATGTGA AATGCCCAGG ATGCTATAAA ATCACCACGG TCTTTAGCCA TGCACAAACG 
GTAGTTTTGT GTGTTGGCTG CTCCACTGTC CTCTGCCAGC CTACAGGAGG AAAAGCAAGG 
CTTACAGAAG GATGTTCCTT CAGGAGGAAG CAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336875.1
CDS	260..418
Translation	MDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Target ORF information:

RefSeq Version	NM_001349946.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349946.1

ORF Insert Sequence:

1
61
121

ATGGATGTGA AATGCCCAGG ATGCTATAAA ATCACCACGG TCTTTAGCCA TGCACAAACG 
GTAGTTTTGT GTGTTGGCTG CTCCACTGTC CTCTGCCAGC CTACAGGAGG AAAAGCAAGG 
CTTACAGAAG GATGTTCCTT CAGGAGGAAG CAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS27 ( NM_001349947.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336876.1 Homo sapiens ribosomal protein S27 (RPS27), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu101190
Clone ID Related Accession (Same CDS sequence)	NM_001349946.1 , NM_001349947.1
Accession Version	NM_001349947.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 159bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	40S ribosomal protein S27 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD175039.1, BC070219.1, BP276426.1 and AJ572583.1. Transcript Variant: This variant (3) retains an intron in its 5' UTR compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. Variants 2 and 3 encode the same isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL698345.1, CD556835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121

ATGGATGTGA AATGCCCAGG ATGCTATAAA ATCACCACGG TCTTTAGCCA TGCACAAACG 
GTAGTTTTGT GTGTTGGCTG CTCCACTGTC CTCTGCCAGC CTACAGGAGG AAAAGCAAGG 
CTTACAGAAG GATGTTCCTT CAGGAGGAAG CAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336876.1
CDS	371..529
Translation	MDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH

Target ORF information:

RefSeq Version	NM_001349947.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S27 (RPS27), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349947.1

ORF Insert Sequence:

1
61
121

ATGGATGTGA AATGCCCAGG ATGCTATAAA ATCACCACGG TCTTTAGCCA TGCACAAACG 
GTAGTTTTGT GTGTTGGCTG CTCCACTGTC CTCTGCCAGC CTACAGGAGG AAAAGCAAGG 
CTTACAGAAG GATGTTCCTT CAGGAGGAAG CAGCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CFTR modulates RPS27 gene expression using chloride anion as signaling effector.
Archives of biochemistry and biophysics633103-109(2017 Nov)
Valdivieso ?G,Mori C,Clauzure M,Massip-Copiz M,Santa-Coloma TA

Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation.
Developmental cell41(2)143-156.e6(2017 04)
Maciejowski J,Drechsler H,Grundner-Culemann K,Ballister ER,Rodriguez-Rodriguez JA,Rodriguez-Bravo V,Jones MJK,Foley E,Lampson MA,Daub H,McAinsh AD,Jallepalli PV

A Novel Marker for Purkinje Cells, Ribosomal Protein MPS1/S27: Expression of MPS1 in Human Cerebellum.
Cancer genomics & proteomics13(1)47-53(2016 Jan-Feb)
Fernandez-Pol JA

Loss of function mutations in RPL27 and RPS27 identified by whole-exome sequencing in Diamond-Blackfan anaemia.
British journal of haematology168(6)854-64(2015 Mar)
Wang R,Yoshida K,Toki T,Sawada T,Uechi T,Okuno Y,Sato-Otsubo A,Kudo K,Kamimaki I,Kanezaki R,Shiraishi Y,Chiba K,Tanaka H,Terui K,Sato T,Iribe Y,Ohga S,Kuramitsu M,Hamaguchi I,Ohara A,Hara J,Goi K,Matsubara K,Koike K,Ishiguro A,Okamoto Y,Watanabe K,Kanno H,Kojima S,Miyano S,Kenmochi N,Ogawa S,Ito E

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RPS27 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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