RPS26 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPS26
Entrez Gene ID	6231
Full Name	ribosomal protein S26
Synonyms	DBA10,S26
General protein information	Preferred Names ribosomal protein S26 Names 40S ribosomal protein S26 small ribosomal subunit protein eS26
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 12 Map Location: 12q13.2
Summary	This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. Mutations in this gene are found in Diamond-Blackfan anemia 10. There are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Aug 2017].
Disorder MIM:	603701
Disorder Html:	Diamond-Blackfan anemia 10, 613309 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001029.4	NP_001020.2	40S ribosomal protein S26
NM_001029.5	NP_001020.2	40S ribosomal protein S26
NM_001029.3	NP_001020.2	40S ribosomal protein S26

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RPS26	XP_531628.1
Rattus norvegicus (Norway rat)	Rps26	NP_037356.1
Rattus norvegicus (Norway rat)	LOC100360508	XP_002728047.2
Gallus gallus (chicken)	RPS26	XP_003643590.1
Danio rerio (zebrafish)	rps26	NP_956319.1
Drosophila melanogaster (fruit fly)	RpS26	NP_001260537.1
Saccharomyces cerevisiae (baker's yeast)	RPS26B	NP_011057.1
Arabidopsis thaliana (thale cress)	AT3G56340	NP_191193.1
Arabidopsis thaliana (thale cress)	AT2G40510	NP_181583.1
Eremothecium gossypii	AGOS_AFR194W	NP_985741.1
Xenopus tropicalis (tropical clawed frog)	rps26	NP_001005121.1
Caenorhabditis elegans (roundworm)	rps-26	NP_493571.1
Saccharomyces cerevisiae (baker's yeast)	RPS26A	NP_011326.1
Kluyveromyces lactis	KLLA0D05115g	XP_453288.1
Schizosaccharomyces pombe (fission yeast)	rps2601	NP_592853.1
Magnaporthe oryzae (rice blast fungus)	MGG_07929	XP_003713174.1
Arabidopsis thaliana (thale cress)	AT2G40590	NP_181591.1
Homo sapiens (human)	RPS26	NP_001020.2
Pan troglodytes (chimpanzee)	RPS26	NP_001239518.1
	LOC718588	XP_001116473.1
Mus musculus (house mouse)	Rps26	NP_038793.2
Danio rerio (zebrafish)	rps26l	NP_957036.1
Neurospora crassa	NCU04552	XP_955943.1
Bos taurus (cattle)	RPS26	NP_001015561.1
Anopheles gambiae (African malaria mosquito)	RS26_ANOGA	XP_320428.3
Schizosaccharomyces pombe (fission yeast)	rps2602	NP_593922.1

Gene Ontology
Bibliography

Related articles in PubMed

Structural snapshots of actively translating human ribosomes.
Behrmann E, Loerke J, Budkevich TV, Yamamoto K, Schmidt A, Penczek PA, Vos MR, B?rger J, Mielke T, Scheerer P, Spahn CM
Cell161(4)845-57(2015 May)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RPS26 acts distinctively in different scenarios of p53 activation.
Title: The ribosomal protein S26 regulates p53 activity in response to DNA damage.

High frequency of RPS26 gene deletion is associated with Italian Diamond-Blackfan anemia.
Title: High frequency of ribosomal protein gene deletions in Italian Diamond-Blackfan anemia patients detected by multiplex ligation-dependent probe amplification assay.

Studies identified deletions at known Diamond-Blackfan anemia (DBA)-related ribosomal protein gene loci in 17% (9 of 51) of patients without an identifiable mutation, including RPS19, RPS17, RPS26, and RPL35A.
Title: Ribosomal protein gene deletions in Diamond-Blackfan anemia.

the Czech Diamond-Blackfan Anemia(DBA) Registry comprises patients with mutations in five different RPs: RPS 19,5,26,11,17, together amounting to 67.3% of resolved cases, and making RPS26 the third most mutated gene in Czech DBA patients.
Title: Can mutations in the ribosomal protein S26 (RPS26) gene lead to Klippel-Feil syndrome in Diamond-Blackfan anemia patients? An update from the Czech Diamond-Blackfan Anemia registry.

Mutations in the RPS10 and RPS26 genes in DBA patients affect the function of the proteins in rRNA processing.
Title: Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia.

The following RPS26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18062	NM_001029.5 Latest version!	Homo sapiens ribosomal protein S26 (RPS26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu18062	NM_001029.4	Homo sapiens ribosomal protein S26 (RPS26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18062	NM_001029.3	Homo sapiens ribosomal protein S26 (RPS26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPS26 ( NM_001029.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001020.2 Homo sapiens ribosomal protein S26 (RPS26), mRNA.

Price & Availability↑

CloneID	OHu18062
Clone ID Related Accession (Same CDS sequence)	NM_001029.4 , NM_001029.5 , NM_001029.3
Accession Version	NM_001029.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-03
Organism	Homo sapiens(human)
Product	40S ribosomal protein S26
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BG777482.1, AV681946.1, BC002604.1, CF129685.1 and AC034102.32. On Aug 24, 2017 this sequence version replaced NM_001029.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.524780.1, SRR1163658.94324.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACAAAGA AAAGAAGGAA CAATGGTCGT GCCAAAAAGG GCCGCGGCCA CGTGCAGCCT 
ATTCGCTGCA CTAACTGTGC CCGATGCGTG CCCAAGGACA AGGCCATTAA GAAATTCGTC 
ATTCGAAACA TAGTGGAGGC CGCAGCAGTC AGGGACATTT CTGAAGCGAG CGTCTTCGAT 
GCCTATGTGC TTCCCAAGCT GTATGTGAAG CTACATTACT GTGTGAGTTG TGCAATTCAC 
AGCAAAGTAG TCAGGAATCG ATCTCGTGAA GCCCGCAAGG ACCGAACACC CCCACCCCGA 
TTTAGACCTG CGGGTGCTGC CCCACGTCCC CCACCAAAGC CCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020.2
CDS	313..660
Translation	MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFRPAGAAPRPPPKPM

Target ORF information:

RefSeq Version	NM_001029.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S26 (RPS26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001029.4

ORF Insert Sequence:

ATGACAAAGA AAAGAAGGAA CAATGGTCGT GCCAAAAAGG GCCGCGGCCA CGTGCAGCCT 
ATTCGCTGCA CTAACTGTGC CCGATGCGTG CCCAAGGACA AGGCCATTAA GAAATTCGTC 
ATTCGAAACA TAGTGGAGGC CGCAGCAGTC AGGGACATTT CTGAAGCGAG CGTCTTCGAT 
GCCTATGTGC TTCCCAAGCT GTATGTGAAG CTACATTACT GTGTGAGTTG TGCAATTCAC 
AGCAAAGTAG TCAGGAATCG ATCTCGTGAA GCCCGCAAGG ACCGAACACC CCCACCCCGA 
TTTAGACCTG CGGGTGCTGC CCCACGTCCC CCACCAAAGC CCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS26 ( NM_001029.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001020.2 Homo sapiens ribosomal protein S26 (RPS26), mRNA.

Price & Availability↑

CloneID	OHu18062
Clone ID Related Accession (Same CDS sequence)	NM_001029.4 , NM_001029.5 , NM_001029.3
Accession Version	NM_001029.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	40S ribosomal protein S26
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AV681946.1, BC002604.1, CF129685.1 and AC034102.32. This sequence is a reference standard in the RefSeqGene project. On May 17, 2018 this sequence version replaced NM_001029.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.412434.1, SRR1163655.524780.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000646449.2/ ENSP00000496643.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACAAAGA AAAGAAGGAA CAATGGTCGT GCCAAAAAGG GCCGCGGCCA CGTGCAGCCT 
ATTCGCTGCA CTAACTGTGC CCGATGCGTG CCCAAGGACA AGGCCATTAA GAAATTCGTC 
ATTCGAAACA TAGTGGAGGC CGCAGCAGTC AGGGACATTT CTGAAGCGAG CGTCTTCGAT 
GCCTATGTGC TTCCCAAGCT GTATGTGAAG CTACATTACT GTGTGAGTTG TGCAATTCAC 
AGCAAAGTAG TCAGGAATCG ATCTCGTGAA GCCCGCAAGG ACCGAACACC CCCACCCCGA 
TTTAGACCTG CGGGTGCTGC CCCACGTCCC CCACCAAAGC CCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020.2
CDS	250..597
Translation	MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFRPAGAAPRPPPKPM

Target ORF information:

RefSeq Version	NM_001029.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S26 (RPS26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001029.5

ORF Insert Sequence:

ATGACAAAGA AAAGAAGGAA CAATGGTCGT GCCAAAAAGG GCCGCGGCCA CGTGCAGCCT 
ATTCGCTGCA CTAACTGTGC CCGATGCGTG CCCAAGGACA AGGCCATTAA GAAATTCGTC 
ATTCGAAACA TAGTGGAGGC CGCAGCAGTC AGGGACATTT CTGAAGCGAG CGTCTTCGAT 
GCCTATGTGC TTCCCAAGCT GTATGTGAAG CTACATTACT GTGTGAGTTG TGCAATTCAC 
AGCAAAGTAG TCAGGAATCG ATCTCGTGAA GCCCGCAAGG ACCGAACACC CCCACCCCGA 
TTTAGACCTG CGGGTGCTGC CCCACGTCCC CCACCAAAGC CCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS26 ( NM_001029.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001020.2 Homo sapiens ribosomal protein S26 (RPS26), mRNA.

Price & Availability↑

CloneID	OHu18062
Clone ID Related Accession (Same CDS sequence)	NM_001029.4 , NM_001029.5 , NM_001029.3
Accession Version	NM_001029.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-26
Organism	Homo sapiens(Human)
Product	40S ribosomal protein S26
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AV681946.1 and BC002604.1. This sequence is a reference standard in the RefSeqGene project. On Aug 1, 2005 this sequence version replaced NM_001029.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD174788.1, SRR1163655.537929.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGACAAAGA AAAGAAGGAA CAATGGTCGT GCCAAAAAGG GCCGCGGCCA CGTGCAGCCT 
ATTCGCTGCA CTAACTGTGC CCGATGCGTG CCCAAGGACA AGGCCATTAA GAAATTCGTC 
ATTCGAAACA TAGTGGAGGC CGCAGCAGTC AGGGACATTT CTGAAGCGAG CGTCTTCGAT 
GCCTATGTGC TTCCCAAGCT GTATGTGAAG CTACATTACT GTGTGAGTTG TGCAATTCAC 
AGCAAAGTAG TCAGGAATCG ATCTCGTGAA GCCCGCAAGG ACCGAACACC CCCACCCCGA 
TTTAGACCTG CGGGTGCTGC CCCACGTCCC CCACCAAAGC CCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020.2
CDS	266..613
Translation	MTKKRRNNGRAKKGRGHVQPIRCTNCARCVPKDKAIKKFVIRNIVEAAAVRDISEASVFDAYVLPKLYVKLHYCVSCAIHSKVVRNRSREARKDRTPPPRFRPAGAAPRPPPKPM

Target ORF information:

RefSeq Version	NM_001029.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens ribosomal protein S26 (RPS26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001029.3

ORF Insert Sequence:

ATGACAAAGA AAAGAAGGAA CAATGGTCGT GCCAAAAAGG GCCGCGGCCA CGTGCAGCCT 
ATTCGCTGCA CTAACTGTGC CCGATGCGTG CCCAAGGACA AGGCCATTAA GAAATTCGTC 
ATTCGAAACA TAGTGGAGGC CGCAGCAGTC AGGGACATTT CTGAAGCGAG CGTCTTCGAT 
GCCTATGTGC TTCCCAAGCT GTATGTGAAG CTACATTACT GTGTGAGTTG TGCAATTCAC 
AGCAAAGTAG TCAGGAATCG ATCTCGTGAA GCCCGCAAGG ACCGAACACC CCCACCCCGA 
TTTAGACCTG CGGGTGCTGC CCCACGTCCC CCACCAAAGC CCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural snapshots of actively translating human ribosomes.
Cell161(4)845-57(2015 May)
Behrmann E,Loerke J,Budkevich TV,Yamamoto K,Schmidt A,Penczek PA,Vos MR,B?rger J,Mielke T,Scheerer P,Spahn CM

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

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RPS26 cDNA ORF clone, Homo sapiens(Human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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