RPS21 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPS21
Entrez Gene ID	6227
Full Name	ribosomal protein S21
Synonyms	HLDF,S21
General protein information	Preferred Names ribosomal protein S21 Names 40S ribosomal protein S21 8.2 kDa differentiation factor human leukemia differentiation factor small ribosomal subunit protein eS21
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S21E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants that encode different protein isoforms have been described, but their existence has not been verified. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
Disorder MIM:	180477

mRNA and Protein(s)

mRNA	Protein	Name
XM_024451960.1	XP_024307728.1	40S ribosomal protein S21 isoform X2
NM_001024.4	NP_001015.1	40S ribosomal protein S21
NM_001024.3	NP_001015.1	40S ribosomal protein S21
XM_024451959.1	XP_024307727.1	40S ribosomal protein S21 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RPS21	XP_543084.2
Bos taurus (cattle)	RPS21	NP_001035671.1
Rattus norvegicus (Norway rat)	Rps21	NP_112373.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009431	XP_307843.4
Caenorhabditis elegans (roundworm)	rps-21	NP_498579.2
Saccharomyces cerevisiae (baker's yeast)	RPS21B	NP_012399.1
Arabidopsis thaliana (thale cress)	AT3G53890	NP_001078280.1
Oryza sativa (rice)	Os03g0345200	NP_001050088.1
Mus musculus (house mouse)	Rps21	NP_079863.1
Danio rerio (zebrafish)	rps21	NP_957485.1
Saccharomyces cerevisiae (baker's yeast)	RPS21A	NP_012983.3
Eremothecium gossypii	AGOS_ACR255C	NP_983657.1
Schizosaccharomyces pombe (fission yeast)	rps21	NP_595852.1
Gallus gallus (chicken)	RPS21	XP_417405.3
Neurospora crassa	NCU08627	XP_964835.1
Xenopus tropicalis (tropical clawed frog)	rps21	NP_001005126.1
Pan troglodytes (chimpanzee)	RPS21	XP_001144993.3
Pan troglodytes (chimpanzee)	LOC458388	XP_514766.2
Homo sapiens (human)	RPS21	NP_001015.1
	RPS21	XP_001088137.1
Drosophila melanogaster (fruit fly)	RpS21	NP_722854.1
Kluyveromyces lactis	KLLA0A05700g	XP_451253.1
Magnaporthe oryzae (rice blast fungus)	MGG_06837	XP_003709553.1
Arabidopsis thaliana (thale cress)	AT5G27700	NP_198122.4
Oryza sativa (rice)	Os03g0667800	NP_001050855.2

Gene Ontology
Bibliography

Related articles in PubMed

Expression of ribosomal proteins in normal and cancerous human prostate tissue.
Arthurs C, Murtaza BN, Thomson C, Dickens K, Henrique R, Patel HRH, Beltran M, Millar M, Thrasivoulou C, Ahmed A
PloS one12(10)e0186047(2017)

Specific effect of the HLDF differentiation factor on the cytokine production potential of immunocompetent blood cells in stomach adenocarcinoma.
Autenshlyus AI, Kunts TA, Mikhaylova ES, Varaksin NA, Bogachuk AP, Lipkin VM
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections469(1)199-201(2016 Jul)

Structural snapshots of actively translating human ribosomes.
Behrmann E, Loerke J, Budkevich TV, Yamamoto K, Schmidt A, Penczek PA, Vos MR, B?rger J, Mielke T, Scheerer P, Spahn CM
Cell161(4)845-57(2015 May)

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, R?der MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC, , , , , , Kote-Jarai Z, Easton DF
Nature genetics45(4)385-91, 391e1-2(2013 Apr)

Involvement of HLDF protein and anti-HLDF antibodies in the mechanisms of blood pressure regulation in healthy individuals and patients with stable hypertension and hypertensive crisis.
Elistratova EI, Gruden MA, Sherstnev VV
Bulletin of experimental biology and medicine153(5)664-6(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results show that RPS19, RPS21 or RPS24 are upregulated in malignant tissue and may serve as putative biomarkers for prostate cancer.
Title: Expression of ribosomal proteins in normal and cancerous human prostate tissue.

Specific effects of HLDF+PA were manifested as an increase in the production of IL-8, IL-17, and GM-CSF due to suppression of Th1-dependent immune reactions in a Th17-mediated mechanism that is a part of a broader functional antagonism of Th1 and Th17 lymphocyte subpopulations.
Title: Specific effect of the HLDF differentiation factor on the cytokine production potential of immunocompetent blood cells in stomach adenocarcinoma.

HLDF protein and anti-HLDF antibodies are involved in blood pressure regulation and can be considered as biomarkers for early diagnosis of hypertension and its cerebral complications.
Title: Involvement of HLDF protein and anti-HLDF antibodies in the mechanisms of blood pressure regulation in healthy individuals and patients with stable hypertension and hypertensive crisis.

The following RPS21 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS21 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08998	NM_001024.4 Latest version!	Homo sapiens ribosomal protein S21 (RPS21), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu105149	XM_024451959.1 Latest version!	Homo sapiens ribosomal protein S21 (RPS21), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu105150	XM_024451960.1 Latest version!	Homo sapiens ribosomal protein S21 (RPS21), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu08998	NM_001024.3	Homo sapiens ribosomal protein S21 (RPS21), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPS21 ( NM_001024.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001015.1 Homo sapiens ribosomal protein S21 (RPS21), mRNA.

Price & Availability↑

CloneID	OHu08998
Clone ID Related Accession (Same CDS sequence)	NM_001024.4 , NM_001024.3
Accession Version	NM_001024.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	40S ribosomal protein S21
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BM840443.1, L04483.1 and CF124568.1. On Nov 22, 2018 this sequence version replaced NM_001024.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM794524.1, BP317659.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343986.9/ ENSP00000345957.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGAACG ACGCCGGCGA GTTCGTGGAC CTGTACGTGC CGCGGAAATG CTCCGCTAGC 
AATCGCATCA TCGGTGCCAA GGACCACGCA TCCATCCAGA TGAACGTGGC CGAGGTTGAC 
AAGGTCACAG GCAGGTTTAA TGGCCAGTTT AAAACTTATG CTATCTGCGG GGCCATTCGT 
AGGATGGGTG AGTCAGATGA TTCCATTCTC CGATTGGCCA AGGCCGATGG CATCGTCTCA 
AAGAACTTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001015.1
CDS	53..304
Translation	MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF

Target ORF information:

RefSeq Version	NM_001024.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S21 (RPS21), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024.4

ORF Insert Sequence:

ATGCAGAACG ACGCCGGCGA GTTCGTGGAC CTGTACGTGC CGCGGAAATG CTCCGCTAGC 
AATCGCATCA TCGGTGCCAA GGACCACGCA TCCATCCAGA TGAACGTGGC CGAGGTTGAC 
AAGGTCACAG GCAGGTTTAA TGGCCAGTTT AAAACTTATG CTATCTGCGG GGCCATTCGT 
AGGATGGGTG AGTCAGATGA TTCCATTCTC CGATTGGCCA AGGCCGATGG CATCGTCTCA 
AAGAACTTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS21 ( NM_001024.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001015.1 Homo sapiens ribosomal protein S21 (RPS21), mRNA.

Price & Availability↑

CloneID	OHu08998
Clone ID Related Accession (Same CDS sequence)	NM_001024.4 , NM_001024.3
Accession Version	NM_001024.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-25
Organism	Homo sapiens(human)
Product	40S ribosomal protein S21
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BM840443.1, L04483.1 and CF124568.1. On Jul 29, 2005 this sequence version replaced NM_001024.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM846292.1, BU858327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCAGAACG ACGCCGGCGA GTTCGTGGAC CTGTACGTGC CGCGGAAATG CTCCGCTAGC 
AATCGCATCA TCGGTGCCAA GGACCACGCA TCCATCCAGA TGAACGTGGC CGAGGTTGAC 
AAGGTCACAG GCAGGTTTAA TGGCCAGTTT AAAACTTATG CTATCTGCGG GGCCATTCGT 
AGGATGGGTG AGTCAGATGA TTCCATTCTC CGATTGGCCA AGGCCGATGG CATCGTCTCA 
AAGAACTTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001015.1
CDS	91..342
Translation	MQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMGESDDSILRLAKADGIVSKNF

Target ORF information:

RefSeq Version	NM_001024.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S21 (RPS21), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024.3

ORF Insert Sequence:

ATGCAGAACG ACGCCGGCGA GTTCGTGGAC CTGTACGTGC CGCGGAAATG CTCCGCTAGC 
AATCGCATCA TCGGTGCCAA GGACCACGCA TCCATCCAGA TGAACGTGGC CGAGGTTGAC 
AAGGTCACAG GCAGGTTTAA TGGCCAGTTT AAAACTTATG CTATCTGCGG GGCCATTCGT 
AGGATGGGTG AGTCAGATGA TTCCATTCTC CGATTGGCCA AGGCCGATGG CATCGTCTCA 
AAGAACTTTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS21 ( XM_024451959.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307727.1 Homo sapiens ribosomal protein S21 (RPS21), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu105149
Clone ID Related Accession (Same CDS sequence)	XM_024451959.1
Accession Version	XM_024451959.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	40S ribosomal protein S21 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTTTC GGGGTCCAAG GGTATGCACC TCTAGCACTA CGACAAACGC GGCCAACACG 
CTTCAGGGAA ACGGTGCCCC AGTTTGCATT CTGCTTCCCC TGCCCTGCCC TGGGGGTCTG 
ACTGGTGAAA CATGGGATGG CAGAGTGGTC GGGTGTTTCA GATTCCACGG TGGGCCGGGG 
TCTTTTCCTA CCCTCGGGAG CCGTCTGAAT TTCTCCTCTG CCGAGTTCCT GCGGGTGTCC 
TTCGCCCACC GGCCCGGGGG AGTGAGTAGC AGGCACCAGG TGAGCAGGCC TCCGCTCGCA 
GCGGCTACGT GCACGGGCAG GAGCACCGCC CCACGCCCCA GGTGGCCGCA GGGTGAGGGG 
ACCGGAGGGC GGGAGGCGCA CAATGGGGGG CACGCCCGTA TCTCTAGCCC GGCCGGCAGC 
GGGCAGCGAG GCTCAGTCCT CGCCCCTTCT CCCAGCTGCT ATTCGGGGCT CCCGAGGCGC 
TCAGAGGGGT CGACTGCGTC CGTGGGGCAC AACCCAGGGG CCAGGCTAAG ACGCCACACA 
CGGCAACGAC CCTCAACGAC AACGACCCCC ACGACGCCCC GCGCCCCAGG GCCAGCAGGC 
TGGGGTCCGA GAACCTCCTT GCCGGAAGCG GAAGTGCGTC ACGGCGACGG CCGGCAAGCA 
CGCACCGCGC AGACTCGCTG TGGTGGCGTG ACCCGGAAGC GCTCGCCGAG GCCCCTCCTT 
GCCCGCCGAT ATCTCTGCCG GGTGACTAGC TGCTTCCTTT CTCTCTCGCG CGCGGTGTGG 
TGGCAGCAGG CGCAGCCCAG CCTCGAAATG CAGAACGACG CCGGCGAGTT CGTGGACCTG 
TACGTGCCGC GGAAATGCTC CGCTAGCAAT CGCATCATCG GTGCCAAGGA CCACGCATCC 
ATCCAGATGA ACGTGGCCGA GGTTGACAAG GTCACAGGCA GGTTTAATGG CCAGTTTAAA 
ACTTATGCTA TCTGCGGGGC CATTCGTAGG ATGGTGAGTG TTTCCCTGGG CTTTGCTCAT 
CACTTCGGGA CATCGTGGAC TTTACCGTGC GCATTGGAGT GTGTGATGGT GCCTGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307727.1
CDS	74..1153
Translation	MGFRGPRVCTSSTTTNAANTLQGNGAPVCILLPLPCPGGLTGETWDGRVVGCFRFHGGPGSFPTLGSRLNFSSAEFLRVSFAHRPGGVSSRHQVSRPPLAAATCTGRSTAPRPRWPQGEGTGGREAHNGGHARISSPAGSGQRGSVLAPSPSCYSGLPRRSEGSTASVGHNPGARLRRHTRQRPSTTTTPTTPRAPGPAGWGPRTSLPEAEVRHGDGRQARTAQTRCGGVTRKRSPRPLLARRYLCRVTSCFLSLSRAVWWQQAQPSLEMQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEVDKVTGRFNGQFKTYAICGAIRRMVSVSLGFAHHFGTSWTLPCALECVMVPE

Target ORF information:

RefSeq Version	XM_024451959.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S21 (RPS21), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451959.1

ORF Insert Sequence:

ATGGGTTTTC GGGGTCCAAG GGTATGCACC TCTAGCACTA CGACAAACGC GGCCAACACG 
CTTCAGGGAA ACGGTGCCCC AGTTTGCATT CTGCTTCCCC TGCCCTGCCC TGGGGGTCTG 
ACTGGTGAAA CATGGGATGG CAGAGTGGTC GGGTGTTTCA GATTCCACGG TGGGCCGGGG 
TCTTTTCCTA CCCTCGGGAG CCGTCTGAAT TTCTCCTCTG CCGAGTTCCT GCGGGTGTCC 
TTCGCCCACC GGCCCGGGGG AGTGAGTAGC AGGCACCAGG TGAGCAGGCC TCCGCTCGCA 
GCGGCTACGT GCACGGGCAG GAGCACCGCC CCACGCCCCA GGTGGCCGCA GGGTGAGGGG 
ACCGGAGGGC GGGAGGCGCA CAATGGGGGG CACGCCCGTA TCTCTAGCCC GGCCGGCAGC 
GGGCAGCGAG GCTCAGTCCT CGCCCCTTCT CCCAGCTGCT ATTCGGGGCT CCCGAGGCGC 
TCAGAGGGGT CGACTGCGTC CGTGGGGCAC AACCCAGGGG CCAGGCTAAG ACGCCACACA 
CGGCAACGAC CCTCAACGAC AACGACCCCC ACGACGCCCC GCGCCCCAGG GCCAGCAGGC 
TGGGGTCCGA GAACCTCCTT GCCGGAAGCG GAAGTGCGTC ACGGCGACGG CCGGCAAGCA 
CGCACCGCGC AGACTCGCTG TGGTGGCGTG ACCCGGAAGC GCTCGCCGAG GCCCCTCCTT 
GCCCGCCGAT ATCTCTGCCG GGTGACTAGC TGCTTCCTTT CTCTCTCGCG CGCGGTGTGG 
TGGCAGCAGG CGCAGCCCAG CCTCGAAATG CAGAACGACG CCGGCGAGTT CGTGGACCTG 
TACGTGCCGC GGAAATGCTC CGCTAGCAAT CGCATCATCG GTGCCAAGGA CCACGCATCC 
ATCCAGATGA ACGTGGCCGA GGTTGACAAG GTCACAGGCA GGTTTAATGG CCAGTTTAAA 
ACTTATGCTA TCTGCGGGGC CATTCGTAGG ATGGTGAGTG TTTCCCTGGG CTTTGCTCAT 
CACTTCGGGA CATCGTGGAC TTTACCGTGC GCATTGGAGT GTGTGATGGT GCCTGAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS21 ( XM_024451960.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307728.1 Homo sapiens ribosomal protein S21 (RPS21), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu105150
Clone ID Related Accession (Same CDS sequence)	XM_024451960.1
Accession Version	XM_024451960.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	40S ribosomal protein S21 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTTTTC GGGGTCCAAG GGTATGCACC TCTAGCACTA CGACAAACGC GGCCAACACG 
CTTCAGGGAA ACGGTGCCCC AGTTTGCATT CTGCTTCCCC TGCCCTGCCC TGGGGGTCTG 
ACTGGTGAAA CATGGGATGG CAGAGTGGTC GGGTGTTTCA GATTCCACGG TGGGCCGGGG 
TCTTTTCCTA CCCTCGGGAG CCGTCTGAAT TTCTCCTCTG CCGAGTTCCT GCGGGTGTCC 
TTCGCCCACC GGCCCGGGGG AGTGAGTAGC AGGCACCAGG TGAGCAGGCC TCCGCTCGCA 
GCGGCTACGT GCACGGGCAG GAGCACCGCC CCACGCCCCA GGTGGCCGCA GGGTGAGGGG 
ACCGGAGGGC GGGAGGCGCA CAATGGGGGG CACGCCCGTA TCTCTAGCCC GGCCGGCAGC 
GGGCAGCGAG GCTCAGTCCT CGCCCCTTCT CCCAGCTGCT ATTCGGGGCT CCCGAGGCGC 
TCAGAGGGGT CGACTGCGTC CGTGGGGCAC AACCCAGGGG CCAGGCTAAG ACGCCACACA 
CGGCAACGAC CCTCAACGAC AACGACCCCC ACGACGCCCC GCGCCCCAGG GCCAGCAGGC 
TGGGGTCCGA GAACCTCCTT GCCGGAAGCG GAAGTGCGTC ACGGCGACGG CCGGCAAGCA 
CGCACCGCGC AGACTCGCTG TGGTGGCGTG ACCCGGAAGC GCTCGCCGAG GCCCCTCCTT 
GCCCGCCGAT ATCTCTGCCG GGTGACTAGC TGCTTCCTTT CTCTCTCGCG CGCGGTGTGG 
TGGCAGCAGG CGCAGCCCAG CCTCGAAATG CAGAACGACG CCGGCGAGTT CGTGGACCTG 
TACGTGCCGC GGAAATGCTC CGCTAGCAAT CGCATCATCG GTGCCAAGGA CCACGCATCC 
ATCCAGATGA ACGTGGCCGA GGGTGAGTCA GATGATTCCA TTCTCCGATT GGCCAAGGCC 
GATGGCATCG TCTCAAAGAA CTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307728.1
CDS	74..1060
Translation	MGFRGPRVCTSSTTTNAANTLQGNGAPVCILLPLPCPGGLTGETWDGRVVGCFRFHGGPGSFPTLGSRLNFSSAEFLRVSFAHRPGGVSSRHQVSRPPLAAATCTGRSTAPRPRWPQGEGTGGREAHNGGHARISSPAGSGQRGSVLAPSPSCYSGLPRRSEGSTASVGHNPGARLRRHTRQRPSTTTTPTTPRAPGPAGWGPRTSLPEAEVRHGDGRQARTAQTRCGGVTRKRSPRPLLARRYLCRVTSCFLSLSRAVWWQQAQPSLEMQNDAGEFVDLYVPRKCSASNRIIGAKDHASIQMNVAEGESDDSILRLAKADGIVSKNF

Target ORF information:

RefSeq Version	XM_024451960.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S21 (RPS21), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451960.1

ORF Insert Sequence:

ATGGGTTTTC GGGGTCCAAG GGTATGCACC TCTAGCACTA CGACAAACGC GGCCAACACG 
CTTCAGGGAA ACGGTGCCCC AGTTTGCATT CTGCTTCCCC TGCCCTGCCC TGGGGGTCTG 
ACTGGTGAAA CATGGGATGG CAGAGTGGTC GGGTGTTTCA GATTCCACGG TGGGCCGGGG 
TCTTTTCCTA CCCTCGGGAG CCGTCTGAAT TTCTCCTCTG CCGAGTTCCT GCGGGTGTCC 
TTCGCCCACC GGCCCGGGGG AGTGAGTAGC AGGCACCAGG TGAGCAGGCC TCCGCTCGCA 
GCGGCTACGT GCACGGGCAG GAGCACCGCC CCACGCCCCA GGTGGCCGCA GGGTGAGGGG 
ACCGGAGGGC GGGAGGCGCA CAATGGGGGG CACGCCCGTA TCTCTAGCCC GGCCGGCAGC 
GGGCAGCGAG GCTCAGTCCT CGCCCCTTCT CCCAGCTGCT ATTCGGGGCT CCCGAGGCGC 
TCAGAGGGGT CGACTGCGTC CGTGGGGCAC AACCCAGGGG CCAGGCTAAG ACGCCACACA 
CGGCAACGAC CCTCAACGAC AACGACCCCC ACGACGCCCC GCGCCCCAGG GCCAGCAGGC 
TGGGGTCCGA GAACCTCCTT GCCGGAAGCG GAAGTGCGTC ACGGCGACGG CCGGCAAGCA 
CGCACCGCGC AGACTCGCTG TGGTGGCGTG ACCCGGAAGC GCTCGCCGAG GCCCCTCCTT 
GCCCGCCGAT ATCTCTGCCG GGTGACTAGC TGCTTCCTTT CTCTCTCGCG CGCGGTGTGG 
TGGCAGCAGG CGCAGCCCAG CCTCGAAATG CAGAACGACG CCGGCGAGTT CGTGGACCTG 
TACGTGCCGC GGAAATGCTC CGCTAGCAAT CGCATCATCG GTGCCAAGGA CCACGCATCC 
ATCCAGATGA ACGTGGCCGA GGGTGAGTCA GATGATTCCA TTCTCCGATT GGCCAAGGCC 
GATGGCATCG TCTCAAAGAA CTTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of ribosomal proteins in normal and cancerous human prostate tissue.
PloS one12(10)e0186047(2017)
Arthurs C,Murtaza BN,Thomson C,Dickens K,Henrique R,Patel HRH,Beltran M,Millar M,Thrasivoulou C,Ahmed A

Specific effect of the HLDF differentiation factor on the cytokine production potential of immunocompetent blood cells in stomach adenocarcinoma.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections469(1)199-201(2016 Jul)
Autenshlyus AI,Kunts TA,Mikhaylova ES,Varaksin NA,Bogachuk AP,Lipkin VM

Structural snapshots of actively translating human ribosomes.
Cell161(4)845-57(2015 May)
Behrmann E,Loerke J,Budkevich TV,Yamamoto K,Schmidt A,Penczek PA,Vos MR,B?rger J,Mielke T,Scheerer P,Spahn CM

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Nature genetics45(4)385-91, 391e1-2(2013 Apr)
Eeles RA,Olama AA,Benlloch S,Saunders EJ,Leongamornlert DA,Tymrakiewicz M,Ghoussaini M,Luccarini C,Dennis J,Jugurnauth-Little S,Dadaev T,Neal DE,Hamdy FC,Donovan JL,Muir K,Giles GG,Severi G,Wiklund F,Gronberg H,Haiman CA,Schumacher F,Henderson BE,Le Marchand L,Lindstrom S,Kraft P,Hunter DJ,Gapstur S,Chanock SJ,Berndt SI,Albanes D,Andriole G,Schleutker J,Weischer M,Canzian F,Riboli E,Key TJ,Travis RC,Campa D,Ingles SA,John EM,Hayes RB,Pharoah PD,Pashayan N,Khaw KT,Stanford JL,Ostrander EA,Signorello LB,Thibodeau SN,Schaid D,Maier C,Vogel W,Kibel AS,Cybulski C,Lubinski J,Cannon-Albright L,Brenner H,Park JY,Kaneva R,Batra J,Spurdle AB,Clements JA,Teixeira MR,Dicks E,Lee A,Dunning AM,Baynes C,Conroy D,Maranian MJ,Ahmed S,Govindasami K,Guy M,Wilkinson RA,Sawyer EJ,Morgan A,Dearnaley DP,Horwich A,Huddart RA,Khoo VS,Parker CC,Van As NJ,Woodhouse CJ,Thompson A,Dudderidge T,Ogden C,Cooper CS,Lophatananon A,Cox A,Southey MC,Hopper JL,English DR,Aly M,Adolfsson J,Xu J,Zheng SL,Yeager M,Kaaks R,Diver WR,Gaudet MM,Stern MC,Corral R,Joshi AD,Shahabi A,Wahlfors T,Tammela TL,Auvinen A,Virtamo J,Klarskov P,Nordestgaard BG,R?der MA,Nielsen SF,Bojesen SE,Siddiq A,Fitzgerald LM,Kolb S,Kwon EM,Karyadi DM,Blot WJ,Zheng W,Cai Q,McDonnell SK,Rinckleb AE,Drake B,Colditz G,Wokolorczyk D,Stephenson RA,Teerlink C,Muller H,Rothenbacher D,Sellers TA,Lin HY,Slavov C,Mitev V,Lose F,Srinivasan S,Maia S,Paulo P,Lange E,Cooney KA,Antoniou AC,Vincent D,Bacot F,Tessier DC,,,,,,Kote-Jarai Z,Easton DF

Involvement of HLDF protein and anti-HLDF antibodies in the mechanisms of blood pressure regulation in healthy individuals and patients with stable hypertension and hypertensive crisis.
Bulletin of experimental biology and medicine153(5)664-6(2012 Sep)
Elistratova EI,Gruden MA,Sherstnev VV

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RPS21 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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