RPS14 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPS14
Entrez Gene ID	6208
Full Name	ribosomal protein S14
Synonyms	EMTB,S14
General protein information	Preferred Names ribosomal protein S14 Names 40S ribosomal protein S14 emetine resistance small ribosomal subunit protein uS11
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q33.1
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	130620
Disorder Html:	Macrocytic anemia, refractory, due to 5q deletion, somatic, 153550 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025070.1	NP_001020241.1	40S ribosomal protein S14
NM_001025071.1	NP_001020242.1	40S ribosomal protein S14
XM_017009684.1	XP_016865173.1	40S ribosomal protein S14 isoform X1
NM_005617.3	NP_005608.1	40S ribosomal protein S14
NM_005617.4	NP_005608.1	40S ribosomal protein S14
NM_001025070.2	NP_001020241.1	40S ribosomal protein S14
NM_001025071.2	NP_001020242.1	40S ribosomal protein S14

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RPS14	NP_001071298.1
Kluyveromyces lactis	KLLA0B07623g	XP_451869.1
Eremothecium gossypii	AGOS_AEL152W	NP_984709.1
Schizosaccharomyces pombe (fission yeast)	rps1402	NP_595737.1
Magnaporthe oryzae (rice blast fungus)	MGG_05238	XP_003712792.1
Neurospora crassa	NCU07830	XP_962951.1
Arabidopsis thaliana (thale cress)	AT3G52580	NP_190826.1
Pan troglodytes (chimpanzee)	RPS14	XP_003310957.1
	RPS14	XP_001099589.2
Canis lupus familiaris (dog)	RPS14	XP_867602.1
Gallus gallus (chicken)	RPS14	NP_001025790.1
Saccharomyces cerevisiae (baker's yeast)	RPS14B	NP_012344.1
Arabidopsis thaliana (thale cress)	AT3G11510	NP_187758.1
Homo sapiens (human)	RPS14	NP_005608.1
Saccharomyces cerevisiae (baker's yeast)	RPS14A	NP_009960.2
Oryza sativa (rice)	Os02g0162500	NP_001045982.1
Oryza sativa (rice)	Os04g0413600	NP_001052749.1
Oryza sativa (rice)	Os02g0534800	NP_001047036.1
Xenopus tropicalis (tropical clawed frog)	LOC549476	NP_001016722.1
Caenorhabditis elegans (roundworm)	rps-14	NP_498572.1
Schizosaccharomyces pombe (fission yeast)	rps1401	NP_594187.1
Arabidopsis thaliana (thale cress)	AT2G36160	NP_181158.1
Mus musculus (house mouse)	Rps14	NP_065625.2
Rattus norvegicus (Norway rat)	Rps14	NP_073163.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules.
Sangith N, Srinivasaraghavan K, Sahu I, Desai A, Medipally S, Somavarappu AK, Verma C, Venkatraman P
FEBS open bio4571-83(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Partial silencing of RPS14 inhibits the proliferation of SKM-1, an acute myeloid leukemia cell line, and RPS14 negatively regulates p53 activation in SKM-1 cells.
Title: Ribosomal protein S14 silencing inhibits growth of acute myeloid leukemia transformed from myelodysplastic syndromes via activating p53.

RPS14 stabilized and activated p53 by inhibiting HDM2-mediated p53 polyubiquitination and degradation
Title: hCINAP is a novel regulator of ribosomal protein-HDM2-p53 pathway by controlling NEDDylation of ribosomal protein S14.

Patients with nonclassical Diamond Blackfan anemia and other hypoproliferative anemias may have somatically acquired 5q deletions with RPS14 haploinsufficiency
Title: Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q- syndrome.

Data indicate that RPS14 negates c-Myc functions by directly inhibiting its transcriptional activity and mediating its mRNA degradation via miRNA.
Title: Ribosomal protein S14 negatively regulates c-Myc activity.

lower RPS14 predicts prolonged survival and possible response to lenalidomide in lower risk MDS patients.
Title: Low RPS14 expression in MDS without 5q - aberration confers higher apoptosis rate of nucleated erythrocytes and predicts prolonged survival and possible response to lenalidomide in lower risk non-5q- patients.

The following RPS14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10378	NM_001025070.2 Latest version!	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10378	NM_001025071.2 Latest version!	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10378	NM_005617.4 Latest version!	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu95976	XM_017009684.1 Latest version!	Homo sapiens ribosomal protein S14 (RPS14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu10378	NM_005617.3	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10378	NM_001025070.1	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu10378	NM_001025071.1	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPS14 ( NM_001025070.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020241.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10378
Clone ID Related Accession (Same CDS sequence)	NM_001025070.1 , NM_001025071.1 , NM_005617.3 , NM_005617.4 , NM_001025070.2 , NM_001025071.2
Accession Version	NM_001025070.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC011388.7, BM454896.1 and AA467888.1. Transcript Variant: This variant (2) lacks a small segment in the 5' UTR, as compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC020515.1, SRR1163658.244691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020241.1
CDS	268..723
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Target ORF information:

RefSeq Version	NM_001025070.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025070.1

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS14 ( NM_001025071.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020242.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10378
Clone ID Related Accession (Same CDS sequence)	NM_001025070.1 , NM_001025071.1 , NM_005617.3 , NM_005617.4 , NM_001025070.2 , NM_001025071.2
Accession Version	NM_001025071.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC011388.7, BM557014.1 and AA467888.1. Transcript Variant: This variant (1) represents the longest transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.399761.1, SRR1163657.175637.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020242.1
CDS	274..729
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Target ORF information:

RefSeq Version	NM_001025071.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025071.1

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS14 ( NM_005617.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005608.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu10378
Clone ID Related Accession (Same CDS sequence)	NM_001025070.1 , NM_001025071.1 , NM_005617.3 , NM_005617.4 , NM_001025070.2 , NM_001025071.2
Accession Version	NM_005617.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC011388.7, BC006784.1 and AA467888.1. This sequence is a reference standard in the RefSeqGene project. On Jun 23, 2005 this sequence version replaced NM_005617.2. Transcript Variant: This variant (3) lacks a big segment in the 5' UTR, as compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD174664.1, SRR1163658.411023.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005608.1
CDS	57..512
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Target ORF information:

RefSeq Version	NM_005617.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005617.3

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS14 ( NM_005617.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005608.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu10378
Clone ID Related Accession (Same CDS sequence)	NM_001025070.1 , NM_001025071.1 , NM_005617.3 , NM_005617.4 , NM_001025070.2 , NM_001025071.2
Accession Version	NM_005617.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC011388.7, BC006784.1 and AA467888.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_005617.3. Transcript Variant: This variant (3) lacks a big segment in the 5' UTR, as compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.119410.1, SRR1803613.205922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000407193.7/ ENSP00000385425.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005608.1
CDS	40..495
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Target ORF information:

RefSeq Version	NM_005617.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005617.4

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS14 ( NM_001025070.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020241.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10378
Clone ID Related Accession (Same CDS sequence)	NM_001025070.1 , NM_001025071.1 , NM_005617.3 , NM_005617.4 , NM_001025070.2 , NM_001025071.2
Accession Version	NM_001025070.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC011388.7, BM454896.1 and AA467888.1. On Jun 1, 2019 this sequence version replaced NM_001025070.1. Transcript Variant: This variant (2) lacks a small segment in the 5' UTR, as compared to variant 1. Variants 1-3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC020515.1, SRR1163658.244691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020241.1
CDS	251..706
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Target ORF information:

RefSeq Version	NM_001025070.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025070.2

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS14 ( NM_001025071.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001020242.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10378
Clone ID Related Accession (Same CDS sequence)	NM_001025070.1 , NM_001025071.1 , NM_005617.3 , NM_005617.4 , NM_001025070.2 , NM_001025071.2
Accession Version	NM_001025071.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC011388.7, BM557014.1 and AA467888.1. On May 31, 2019 this sequence version replaced NM_001025071.1. Transcript Variant: This variant (1) represents the longest transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.29299.1, SRR1660809.172087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020242.1
CDS	257..712
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

Target ORF information:

RefSeq Version	NM_001025071.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025071.2

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGAG GATGTCACCC CCATCCCCTC TGACAGCACT 
CGCAGGAAGG GGGGTCGCCG TGGTCGCCGT CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS14 ( XM_017009684.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016865173.1 Homo sapiens ribosomal protein S14 (RPS14), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu95976
Clone ID Related Accession (Same CDS sequence)	XM_017009684.1
Accession Version	XM_017009684.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	40S ribosomal protein S14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGGT AAGTGCCCCC CTCTAGCTAA TGCTTGGGTT 
TATTTTGAAG CATTGGCCCC AAAAAGCACG TGCTGTGCCC AGTGGATGTG CAGCGGCTGG 
TCTGGTCACT TTTGGCAGTT AAGTTTGTTA AGGGAGGCTG CAAGAGGCAC CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016865173.1
CDS	111..647
Translation	MAPRKGKEKKEEQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSALRALARSGMKIGRIGKCPPLANAWVYFEALAPKSTCCAQWMCSGWSGHFWQLSLLREAARGTL

Target ORF information:

RefSeq Version	XM_017009684.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S14 (RPS14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017009684.1

ORF Insert Sequence:

ATGGCACCTC GAAAGGGGAA GGAAAAGAAG GAAGAACAGG TCATCAGCCT CGGACCTCAG 
GTGGCTGAAG GAGAGAATGT ATTTGGTGTC TGCCATATCT TTGCATCCTT CAATGACACT 
TTTGTCCATG TCACTGATCT TTCTGGCAAG GAAACCATCT GCCGTGTGAC TGGTGGGATG 
AAGGTAAAGG CAGACCGAGA TGAATCCTCA CCATATGCTG CTATGTTGGC TGCCCAGGAT 
GTGGCCCAGA GGTGCAAGGA GCTGGGTATC ACCGCCCTAC ACATCAAACT CCGGGCCACA 
GGAGGAAATA GGACCAAGAC CCCTGGACCT GGGGCCCAGT CGGCCCTCAG AGCCCTTGCC 
CGCTCGGGTA TGAAGATCGG GCGGATTGGT AAGTGCCCCC CTCTAGCTAA TGCTTGGGTT 
TATTTTGAAG CATTGGCCCC AAAAAGCACG TGCTGTGCCC AGTGGATGTG CAGCGGCTGG 
TCTGGTCACT TTTGGCAGTT AAGTTTGTTA AGGGAGGCTG CAAGAGGCAC CTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules.
FEBS open bio4571-83(2014)
Sangith N,Srinivasaraghavan K,Sahu I,Desai A,Medipally S,Somavarappu AK,Verma C,Venkatraman P

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RPS14 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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