RPS13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPS13
Entrez Gene ID	6207
Full Name	ribosomal protein S13
Synonyms	S13
General protein information	Preferred Names ribosomal protein S13 Names 40S ribosomal protein S13 small ribosomal subunit protein uS15
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.1
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S15P family of ribosomal proteins. It is located in the cytoplasm. The protein has been shown to bind to the 5.8S rRNA in rat. The gene product of the E. coli ortholog (ribosomal protein S15) functions at early steps in ribosome assembly. This gene is co-transcribed with two U14 small nucleolar RNA genes, which are located in its third and fifth introns. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
Disorder MIM:	180476

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017.3	NP_001008.1	40S ribosomal protein S13
NM_001017.2	NP_001008.1	40S ribosomal protein S13

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	RPS13	NP_001001783.1
Anopheles gambiae (African malaria mosquito)	RS13_ANOGA	XP_315982.2
Kluyveromyces lactis	KLLA0F18040g	XP_455889.2
Neurospora crassa	NCU03038	XP_964043.1
Arabidopsis thaliana (thale cress)	AT3G60770	NP_567104.1
Oryza sativa (rice)	Os08g0117300	NP_001060861.1
	RPS13	XP_001086088.1
Canis lupus familiaris (dog)	RPS13	XP_864902.1
Bos taurus (cattle)	RPS13	NP_001020513.1
Caenorhabditis elegans (roundworm)	rps-13	NP_498393.1
Eremothecium gossypii	AGOS_AGL030W	NP_986636.1
Oryza sativa (rice)	Os08g0117200	NP_001060860.2
Xenopus tropicalis (tropical clawed frog)	rps13	NP_001016602.1
Mus musculus (house mouse)	Rps13	NP_080809.1
Danio rerio (zebrafish)	rps13	NP_001002079.1
Schizosaccharomyces pombe (fission yeast)	rps13	NP_593900.1
Homo sapiens (human)	RPS13	NP_001008.1
Pan troglodytes (chimpanzee)	RPS13	XP_003312983.1
Drosophila melanogaster (fruit fly)	RpS13	NP_476938.1
Magnaporthe oryzae (rice blast fungus)	MGG_00349	XP_003718734.1
Saccharomyces cerevisiae (baker's yeast)	RPS13	NP_010349.3
Arabidopsis thaliana (thale cress)	RPS13A	NP_567151.1

Gene Ontology
Bibliography

Related articles in PubMed

Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein.
Li Y, Jain N, Limpanawat S, To J, Quistgaard EM, Nordlund P, Thanabalu T, Torres J
Virology482105-10(2015 Aug)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, Dawson TM, Dawson VL
Cell157(2)472-485(2014 Apr)

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Zanivan S, Maione F, Hein MY, Hern?ndez-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M
Molecular & cellular proteomics : MCP12(12)3599-611(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

binding of ribosomal protein S13 to 18S rRNA is provided mainly by conserved motifs of the protein corresponding to those motifs in its eubacterial homologue that are involved in the interaction with 16S rRNA in the 30S subunit.
Title: [Binding of human ribosomal protein S13 to the central domain of 18S rRNA].

these data indicate that RPS13 could promote the growth and cell cycle progression of gastric cancer cells at least through inhibiting p27(kip1) expression.
Title: Human ribosomal protein S13 promotes gastric cancer growth through down-regulating p27(Kip1).

Overproduction of rpS13 in mammalian cells interferes with splicing of its own pre-mRNA by a feedback mechanism.
Title: Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism.

Recombinant ribosomal protein S13 expressed in and isolated from E.coli was shown to be suitable for structural and functional investigations.
Title: Human ribosomal protein S13: cloning, expression, refolding, and structural stability.

either RPS13 or RPL23 can promote MDR in gastric cancer cells by suppressing drug-induced apoptosis, and RPL23 may also promote MDR in gastric cancer cells through regulation of glutathione S-transferase-mediated drug-detoxifying system
Title: Ribosomal proteins S13 and L23 promote multidrug resistance in gastric cancer cells by suppressing drug-induced apoptosis.

The following RPS13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13042	NM_001017.3 Latest version!	Homo sapiens ribosomal protein S13 (RPS13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu13042	NM_001017.2	Homo sapiens ribosomal protein S13 (RPS13), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPS13 ( NM_001017.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008.1 Homo sapiens ribosomal protein S13 (RPS13), mRNA.

Price & Availability↑

CloneID	OHu13042
Clone ID Related Accession (Same CDS sequence)	NM_001017.3 , NM_001017.2
Accession Version	NM_001017.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	40S ribosomal protein S13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC116533.11. On Nov 26, 2018 this sequence version replaced NM_001017.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP318859.1, SRR1163655.395667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000525634.6/ ENSP00000435777.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTCGCA TGCATGCTCC CGGGAAGGGC CTGTCCCAGT CGGCTTTACC CTATCGACGC 
AGCGTCCCCA CTTGGTTGAA GTTGACATCT GACGACGTGA AGGAGCAGAT TTACAAACTG 
GCCAAGAAGG GCCTTACTCC TTCACAGATC GGTGTAATCC TGAGAGATTC ACATGGTGTT 
GCACAAGTAC GTTTTGTGAC AGGCAATAAA ATTTTAAGAA TTCTTAAGTC TAAGGGACTT 
GCTCCTGATC TTCCTGAAGA TCTCTACCAT TTAATTAAGA AAGCAGTTGC TGTTCGAAAG 
CATCTTGAGA GGAACAGAAA GGATAAGGAT GCTAAATTCC GTCTGATTCT AATAGAGAGC 
CGGATTCACC GTTTGGCTCG ATATTATAAG ACCAAGCGAG TCCTCCCTCC CAATTGGAAA 
TATGAATCAT CTACAGCCTC TGCCCTGGTC GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008.1
CDS	27..482
Translation	MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

Target ORF information:

RefSeq Version	NM_001017.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S13 (RPS13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017.3

ORF Insert Sequence:

ATGGGTCGCA TGCATGCTCC CGGGAAGGGC CTGTCCCAGT CGGCTTTACC CTATCGACGC 
AGCGTCCCCA CTTGGTTGAA GTTGACATCT GACGACGTGA AGGAGCAGAT TTACAAACTG 
GCCAAGAAGG GCCTTACTCC TTCACAGATC GGTGTAATCC TGAGAGATTC ACATGGTGTT 
GCACAAGTAC GTTTTGTGAC AGGCAATAAA ATTTTAAGAA TTCTTAAGTC TAAGGGACTT 
GCTCCTGATC TTCCTGAAGA TCTCTACCAT TTAATTAAGA AAGCAGTTGC TGTTCGAAAG 
CATCTTGAGA GGAACAGAAA GGATAAGGAT GCTAAATTCC GTCTGATTCT AATAGAGAGC 
CGGATTCACC GTTTGGCTCG ATATTATAAG ACCAAGCGAG TCCTCCCTCC CAATTGGAAA 
TATGAATCAT CTACAGCCTC TGCCCTGGTC GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS13 ( NM_001017.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001008.1 Homo sapiens ribosomal protein S13 (RPS13), mRNA.

Price & Availability↑

CloneID	OHu13042
Clone ID Related Accession (Same CDS sequence)	NM_001017.3 , NM_001017.2
Accession Version	NM_001017.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 456bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	40S ribosomal protein S13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from L01124.1. On Jul 3, 2001 this sequence version replaced NM_001017.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ277838.1, SRR1163655.395667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGTCGCA TGCATGCTCC CGGGAAGGGC CTGTCCCAGT CGGCTTTACC CTATCGACGC 
AGCGTCCCCA CTTGGTTGAA GTTGACATCT GACGACGTGA AGGAGCAGAT TTACAAACTG 
GCCAAGAAGG GCCTTACTCC TTCACAGATC GGTGTAATCC TGAGAGATTC ACATGGTGTT 
GCACAAGTAC GTTTTGTGAC AGGCAATAAA ATTTTAAGAA TTCTTAAGTC TAAGGGACTT 
GCTCCTGATC TTCCTGAAGA TCTCTACCAT TTAATTAAGA AAGCAGTTGC TGTTCGAAAG 
CATCTTGAGA GGAACAGAAA GGATAAGGAT GCTAAATTCC GTCTGATTCT AATAGAGAGC 
CGGATTCACC GTTTGGCTCG ATATTATAAG ACCAAGCGAG TCCTCCCTCC CAATTGGAAA 
TATGAATCAT CTACAGCCTC TGCCCTGGTC GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008.1
CDS	33..488
Translation	MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

Target ORF information:

RefSeq Version	NM_001017.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S13 (RPS13), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017.2

ORF Insert Sequence:

ATGGGTCGCA TGCATGCTCC CGGGAAGGGC CTGTCCCAGT CGGCTTTACC CTATCGACGC 
AGCGTCCCCA CTTGGTTGAA GTTGACATCT GACGACGTGA AGGAGCAGAT TTACAAACTG 
GCCAAGAAGG GCCTTACTCC TTCACAGATC GGTGTAATCC TGAGAGATTC ACATGGTGTT 
GCACAAGTAC GTTTTGTGAC AGGCAATAAA ATTTTAAGAA TTCTTAAGTC TAAGGGACTT 
GCTCCTGATC TTCCTGAAGA TCTCTACCAT TTAATTAAGA AAGCAGTTGC TGTTCGAAAG 
CATCTTGAGA GGAACAGAAA GGATAAGGAT GCTAAATTCC GTCTGATTCT AATAGAGAGC 
CGGATTCACC GTTTGGCTCG ATATTATAAG ACCAAGCGAG TCCTCCCTCC CAATTGGAAA 
TATGAATCAT CTACAGCCTC TGCCCTGGTC GCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein.
Virology482105-10(2015 Aug)
Li Y,Jain N,Limpanawat S,To J,Quistgaard EM,Nordlund P,Thanabalu T,Torres J

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Cell157(2)472-485(2014 Apr)
Martin I,Kim JW,Lee BD,Kang HC,Xu JC,Jia H,Stankowski J,Kim MS,Zhong J,Kumar M,Andrabi SA,Xiong Y,Dickson DW,Wszolek ZK,Pandey A,Dawson TM,Dawson VL

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Molecular & cellular proteomics : MCP12(12)3599-611(2013 Dec)
Zanivan S,Maione F,Hein MY,Hern?ndez-Fernaud JR,Ostasiewicz P,Giraudo E,Mann M

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RPS13 cDNA ORF clone, Homo sapiens(human)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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