RPS11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPS11
Entrez Gene ID	6205
Full Name	ribosomal protein S11
Synonyms	S11
General protein information	Preferred Names ribosomal protein S11 Names 40S ribosomal protein S11 small ribosomal subunit protein uS17
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S17P family of ribosomal proteins that is a component of the 40S subunit. This gene is co-transcribed with the small nucleolar RNA gene U35B, which is located in the third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. [provided by RefSeq, Jul 2012].
Disorder MIM:	180471

mRNA and Protein(s)

mRNA	Protein	Name
NM_001015.5	NP_001006.1	40S ribosomal protein S11
NM_001015.4	NP_001006.1	40S ribosomal protein S11

Pathways from BioSystems

Homologies

	RPS11	XP_001115123.2
Mus musculus (house mouse)	Rps11	NP_038753.1
Rattus norvegicus (Norway rat)	Rps11	NP_112372.1
Anopheles gambiae (African malaria mosquito)	RS11_ANOGA	XP_319141.3
Saccharomyces cerevisiae (baker's yeast)	RPS11A	NP_010308.3
Kluyveromyces lactis	KLLA0A10483g	XP_451459.1
Schizosaccharomyces pombe (fission yeast)	rps1102	NP_594672.1
Neurospora crassa	NCU03102	XP_964961.1
Canis lupus familiaris (dog)	RPS11	XP_533619.2
Drosophila melanogaster (fruit fly)	RpS11	NP_725114.1
Caenorhabditis elegans (roundworm)	rps-11	NP_502186.1
Oryza sativa (rice)	Os07g0565000	NP_001060007.1
Bos taurus (cattle)	RPS11	NP_001019739.1
Arabidopsis thaliana (thale cress)	RPS11-BETA	NP_197763.1
Oryza sativa (rice)	Os04g0613600	NP_001053856.2
Gallus gallus (chicken)	RPS11	NP_001026004.1
Danio rerio (zebrafish)	rps11	NP_998542.1
Eremothecium gossypii	AGOS_ABL091C	NP_982856.1
Arabidopsis thaliana (thale cress)	EMB1080	NP_190462.1
Arabidopsis thaliana (thale cress)	AT4G30800	NP_194809.1
Oryza sativa (rice)	Os04g0502300	NP_001053235.1
Homo sapiens (human)	RPS11	NP_001006.1
Saccharomyces cerevisiae (baker's yeast)	RPS11B	NP_009604.1
Schizosaccharomyces pombe (fission yeast)	rps1101	NP_594003.1
Magnaporthe oryzae (rice blast fungus)	MGG_03680	XP_003716203.1
Xenopus tropicalis (tropical clawed frog)	rps11	NP_001005113.1

Gene Ontology
Bibliography

Related articles in PubMed

Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients.
Yong WH, Shabihkhani M, Telesca D, Yang S, Tso JL, Menjivar JC, Wei B, Lucey GM, Mareninov S, Chen Z, Liau LM, Lai A, Nelson SF, Cloughesy TF, Tso CL
PloS one10(10)e0141334(2015)

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, Dawson TM, Dawson VL
Cell157(2)472-485(2014 Apr)

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Zanivan S, Maione F, Hein MY, Hern?ndez-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M
Molecular & cellular proteomics : MCP12(12)3599-611(2013 Dec)

Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L, , Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Uitterlinden AG, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O' Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP
American journal of human genetics91(4)744-53(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

increased expression of RPS11 and RPS20 predicts shorter patient survival. treatment-resistant GSC clones are clinically relevant cells that represent resistant tumorigenic clones from patient tumors and that their properties
Title: Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients.

The following RPS11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09608	NM_001015.5 Latest version!	Homo sapiens ribosomal protein S11 (RPS11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu09608	NM_001015.4	Homo sapiens ribosomal protein S11 (RPS11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPS11 ( NM_001015.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001006.1 Homo sapiens ribosomal protein S11 (RPS11), mRNA.

Price & Availability↑

CloneID	OHu09608
Clone ID Related Accession (Same CDS sequence)	NM_001015.5 , NM_001015.4
Accession Version	NM_001015.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	40S ribosomal protein S11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AK311809.1 and BI550467.1. On Nov 23, 2018 this sequence version replaced NM_001015.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP344052.1, BI550467.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000270625.7/ ENSP00000270625.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGACA TTCAGACTGA GCGTGCCTAC CAAAAGCAGC CGACCATCTT TCAAAACAAG 
AAGAGGGTCC TGCTGGGAGA AACTGGCAAG GAGAAGCTCC CGCGGTACTA CAAGAACATC 
GGTCTGGGCT TCAAGACACC CAAGGAGGCT ATTGAGGGCA CCTACATTGA CAAGAAATGC 
CCCTTCACTG GTAATGTGTC CATTCGAGGG CGGATCCTCT CTGGCGTGGT GACCAAGATG 
AAGATGCAGA GGACCATTGT CATCCGCCGA GACTATCTGC ACTACATCCG CAAGTACAAC 
CGCTTCGAGA AGCGCCACAA GAACATGTCT GTACACCTGT CCCCCTGCTT CAGGGACGTC 
CAGATCGGTG ACATCGTCAC AGTGGGCGAG TGCCGGCCTC TGAGCAAGAC AGTGCGCTTC 
AACGTGCTCA AGGTCACCAA GGCTGCCGGC ACCAAGAAGC AGTTCCAGAA GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006.1
CDS	24..500
Translation	MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF

Target ORF information:

RefSeq Version	NM_001015.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S11 (RPS11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001015.5

ORF Insert Sequence:

ATGGCGGACA TTCAGACTGA GCGTGCCTAC CAAAAGCAGC CGACCATCTT TCAAAACAAG 
AAGAGGGTCC TGCTGGGAGA AACTGGCAAG GAGAAGCTCC CGCGGTACTA CAAGAACATC 
GGTCTGGGCT TCAAGACACC CAAGGAGGCT ATTGAGGGCA CCTACATTGA CAAGAAATGC 
CCCTTCACTG GTAATGTGTC CATTCGAGGG CGGATCCTCT CTGGCGTGGT GACCAAGATG 
AAGATGCAGA GGACCATTGT CATCCGCCGA GACTATCTGC ACTACATCCG CAAGTACAAC 
CGCTTCGAGA AGCGCCACAA GAACATGTCT GTACACCTGT CCCCCTGCTT CAGGGACGTC 
CAGATCGGTG ACATCGTCAC AGTGGGCGAG TGCCGGCCTC TGAGCAAGAC AGTGCGCTTC 
AACGTGCTCA AGGTCACCAA GGCTGCCGGC ACCAAGAAGC AGTTCCAGAA GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPS11 ( NM_001015.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001006.1 Homo sapiens ribosomal protein S11 (RPS11), mRNA.

Price & Availability↑

CloneID	OHu09608
Clone ID Related Accession (Same CDS sequence)	NM_001015.5 , NM_001015.4
Accession Version	NM_001015.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	40S ribosomal protein S11
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from DA879881.1, AK311809.1 and BI550467.1. On Jul 12, 2012 this sequence version replaced NM_001015.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI550467.1, SRR1163658.201597.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCGGACA TTCAGACTGA GCGTGCCTAC CAAAAGCAGC CGACCATCTT TCAAAACAAG 
AAGAGGGTCC TGCTGGGAGA AACTGGCAAG GAGAAGCTCC CGCGGTACTA CAAGAACATC 
GGTCTGGGCT TCAAGACACC CAAGGAGGCT ATTGAGGGCA CCTACATTGA CAAGAAATGC 
CCCTTCACTG GTAATGTGTC CATTCGAGGG CGGATCCTCT CTGGCGTGGT GACCAAGATG 
AAGATGCAGA GGACCATTGT CATCCGCCGA GACTATCTGC ACTACATCCG CAAGTACAAC 
CGCTTCGAGA AGCGCCACAA GAACATGTCT GTACACCTGT CCCCCTGCTT CAGGGACGTC 
CAGATCGGTG ACATCGTCAC AGTGGGCGAG TGCCGGCCTC TGAGCAAGAC AGTGCGCTTC 
AACGTGCTCA AGGTCACCAA GGCTGCCGGC ACCAAGAAGC AGTTCCAGAA GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001006.1
CDS	93..569
Translation	MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF

Target ORF information:

RefSeq Version	NM_001015.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein S11 (RPS11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001015.4

ORF Insert Sequence:

ATGGCGGACA TTCAGACTGA GCGTGCCTAC CAAAAGCAGC CGACCATCTT TCAAAACAAG 
AAGAGGGTCC TGCTGGGAGA AACTGGCAAG GAGAAGCTCC CGCGGTACTA CAAGAACATC 
GGTCTGGGCT TCAAGACACC CAAGGAGGCT ATTGAGGGCA CCTACATTGA CAAGAAATGC 
CCCTTCACTG GTAATGTGTC CATTCGAGGG CGGATCCTCT CTGGCGTGGT GACCAAGATG 
AAGATGCAGA GGACCATTGT CATCCGCCGA GACTATCTGC ACTACATCCG CAAGTACAAC 
CGCTTCGAGA AGCGCCACAA GAACATGTCT GTACACCTGT CCCCCTGCTT CAGGGACGTC 
CAGATCGGTG ACATCGTCAC AGTGGGCGAG TGCCGGCCTC TGAGCAAGAC AGTGCGCTTC 
AACGTGCTCA AGGTCACCAA GGCTGCCGGC ACCAAGAAGC AGTTCCAGAA GTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in Glioblastoma Patients.
PloS one10(10)e0141334(2015)
Yong WH,Shabihkhani M,Telesca D,Yang S,Tso JL,Menjivar JC,Wei B,Lucey GM,Mareninov S,Chen Z,Liau LM,Lai A,Nelson SF,Cloughesy TF,Tso CL

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Cell157(2)472-485(2014 Apr)
Martin I,Kim JW,Lee BD,Kang HC,Xu JC,Jia H,Stankowski J,Kim MS,Zhong J,Kumar M,Andrabi SA,Xiong Y,Dickson DW,Wszolek ZK,Pandey A,Dawson TM,Dawson VL

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Molecular & cellular proteomics : MCP12(12)3599-611(2013 Dec)
Zanivan S,Maione F,Hein MY,Hern?ndez-Fernaud JR,Ostasiewicz P,Giraudo E,Mann M

Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
American journal of human genetics91(4)744-53(2012 Oct)
Franceschini N,van Rooij FJ,Prins BP,Feitosa MF,Karakas M,Eckfeldt JH,Folsom AR,Kopp J,Vaez A,Andrews JS,Baumert J,Boraska V,Broer L,Hayward C,Ngwa JS,Okada Y,Polasek O,Westra HJ,Wang YA,Del Greco M F,Glazer NL,Kapur K,Kema IP,Lopez LM,Schillert A,Smith AV,Winkler CA,Zgaga L,,Bandinelli S,Bergmann S,Boban M,Bochud M,Chen YD,Davies G,Dehghan A,Ding J,Doering A,Durda JP,Ferrucci L,Franco OH,Franke L,Gunjaca G,Hofman A,Hsu FC,Kolcic I,Kraja A,Kubo M,Lackner KJ,Launer L,Loehr LR,Li G,Meisinger C,Nakamura Y,Schwienbacher C,Starr JM,Takahashi A,Torlak V,Uitterlinden AG,Vitart V,Waldenberger M,Wild PS,Kirin M,Zeller T,Zemunik T,Zhang Q,Ziegler A,Blankenberg S,Boerwinkle E,Borecki IB,Campbell H,Deary IJ,Frayling TM,Gieger C,Harris TB,Hicks AA,Koenig W,O' Donnell CJ,Fox CS,Pramstaller PP,Psaty BM,Reiner AP,Rotter JI,Rudan I,Snieder H,Tanaka T,van Duijn CM,Vollenweider P,Waeber G,Wilson JF,Witteman JC,Wolffenbuttel BH,Wright AF,Wu Q,Liu Y,Jenny NS,North KE,Felix JF,Alizadeh BZ,Cupples LA,Perry JR,Morris AP

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RPS11 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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