Gene Symbol | RPS6KA3 |
Entrez Gene ID | 6197 |
Full Name | ribosomal protein S6 kinase A3 |
Synonyms | CLS,HU-3,ISPK-1,MAPKAPK1B,MRX19,RSK,RSK2,S6K-alpha3,p90-RSK2,pp90RSK2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Coffin-Lowry syndrome, 303600 (3); Mental retardation, X-linked 19, 300844 (3) |