RPL38 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPL38
Entrez Gene ID	6169
Full Name	ribosomal protein L38
Synonyms	L38
General protein information	Preferred Names ribosomal protein L38 Names 60S ribosomal protein L38 large ribosomal subunit protein eL38
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.1
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L38E family of ribosomal proteins. It is located in the cytoplasm. Alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome, including one located in the promoter region of the type 1 angiotensin II receptor gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	604182

mRNA and Protein(s)

mRNA	Protein	Name
NM_000999.4	NP_000990.1	60S ribosomal protein L38
NM_000999.3	NP_000990.1	60S ribosomal protein L38
NM_001035258.2	NP_001030335.1	60S ribosomal protein L38
NM_001035258.1	NP_001030335.1	60S ribosomal protein L38

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	rpl38	NP_001005094.1
Mus musculus (house mouse)	Rpl38	NP_075861.1
Arabidopsis thaliana (thale cress)	AT3G59540	NP_191513.1
Oryza sativa (rice)	Os11g0433900	NP_001067801.1
Oryza sativa (rice)	Os05g0507200	NP_001055990.1
Homo sapiens (human)	RPL38	NP_000990.1
Pan troglodytes (chimpanzee)	RPL38	XP_003315754.1
	LOC710665	XP_001109512.1
Caenorhabditis elegans (roundworm)	rpl-38	NP_506860.1
Bos taurus (cattle)	RPL38	NP_001106780.1
Gallus gallus (chicken)	RPL38	NP_001264941.1
Danio rerio (zebrafish)	rpl38	NP_001002486.1
Drosophila melanogaster (fruit fly)	RpL38	NP_001036440.1
Anopheles gambiae (African malaria mosquito)	RL38_ANOGA	XP_319334.2
Arabidopsis thaliana (thale cress)	AT2G43460	NP_181874.1

Gene Ontology
Bibliography

Related articles in PubMed

Structural snapshots of actively translating human ribosomes.
Behrmann E, Loerke J, Budkevich TV, Yamamoto K, Schmidt A, Penczek PA, Vos MR, B?rger J, Mielke T, Scheerer P, Spahn CM
Cell161(4)845-57(2015 May)

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Kuo JC, Han X, Hsiao CT, Yates JR 3rd, Waterman CM
Nature cell biology13(4)383-93(2011 Apr)

Characterization of the proteome, diseases and evolution of the human postsynaptic density.
Bay?s A, van de Lagemaat LN, Collins MO, Croning MD, Whittle IR, Choudhary JS, Grant SG
Nature neuroscience14(1)19-21(2011 Jan)

A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.
Tsang HT, Connell JW, Brown SE, Thompson A, Reid E, Sanderson CM
Genomics88(3)333-46(2006 Sep)

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Wang AG, Yoon SY, Oh JH, Jeon YJ, Kim M, Kim JM, Byun SS, Yang JO, Kim JH, Kim DG, Yeom YI, Yoo HS, Kim YS, Kim NS
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RPL38 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPL38 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30189	NM_001035258.2 Latest version!	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30189	NM_000999.4 Latest version!	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu30189	NM_000999.3	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu30189	NM_001035258.1	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPL38 ( NM_000999.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000990.1 Homo sapiens ribosomal protein L38 (RPL38), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30189
Clone ID Related Accession (Same CDS sequence)	NM_000999.4 , NM_000999.3 , NM_001035258.2 , NM_001035258.1
Accession Version	NM_000999.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	60S ribosomal protein L38
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BQ276548.1, Z26876.1, CB124619.1 and AC100786.2. On Nov 23, 2018 this sequence version replaced NM_000999.3. Transcript Variant: This variant (1) is the longer and predominant transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.54255.1, CD390038.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311111.11/ ENSP00000309830.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000990.1
CDS	107..319
Translation	MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKELK

Target ORF information:

RefSeq Version	NM_000999.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000999.4

ORF Insert Sequence:

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL38 ( NM_000999.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000990.1 Homo sapiens ribosomal protein L38 (RPL38), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30189
Clone ID Related Accession (Same CDS sequence)	NM_000999.4 , NM_000999.3 , NM_001035258.2 , NM_001035258.1
Accession Version	NM_000999.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	60S ribosomal protein L38
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BQ276548.1, Z26876.1 and CB124619.1. On Oct 28, 2005 this sequence version replaced NM_000999.2. Transcript Variant: This variant (1) is the longer and predominant transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU928193.1, BU569438.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000990.1
CDS	129..341
Translation	MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKELK

Target ORF information:

RefSeq Version	NM_000999.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000999.3

ORF Insert Sequence:

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL38 ( NM_001035258.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001030335.1 Homo sapiens ribosomal protein L38 (RPL38), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30189
Clone ID Related Accession (Same CDS sequence)	NM_000999.4 , NM_000999.3 , NM_001035258.2 , NM_001035258.1
Accession Version	NM_001035258.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	60S ribosomal protein L38
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB128529.1 and AC100786.2. On Jun 1, 2019 this sequence version replaced NM_001035258.1. Transcript Variant: This variant (2) is the shorter transcript, lacking a segment in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: EC457883.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030335.1
CDS	72..284
Translation	MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKELK

Target ORF information:

RefSeq Version	NM_001035258.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001035258.2

ORF Insert Sequence:

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL38 ( NM_001035258.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001030335.1 Homo sapiens ribosomal protein L38 (RPL38), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30189
Clone ID Related Accession (Same CDS sequence)	NM_000999.4 , NM_000999.3 , NM_001035258.2 , NM_001035258.1
Accession Version	NM_001035258.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	60S ribosomal protein L38
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU532782.1 and CB128529.1. Transcript Variant: This variant (2) is the shorter transcript, lacking a segment in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: HY023583.1, BG503862.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030335.1
CDS	94..306
Translation	MPRKIEEIKDFLLTARRKDAKSVKIKKNKDNVKFKVRCSRYLYTLVITDKEKAEKLKQSLPPGLAVKELK

Target ORF information:

RefSeq Version	NM_001035258.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L38 (RPL38), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001035258.1

ORF Insert Sequence:

ATGCCTCGGA AAATTGAGGA AATCAAGGAC TTCCTGCTCA CAGCCCGACG AAAGGATGCC 
AAATCTGTCA AGATCAAGAA AAATAAGGAC AACGTGAAGT TTAAAGTTCG ATGCAGCAGA 
TACCTTTACA CCCTGGTCAT CACTGACAAA GAGAAGGCAG AGAAACTGAA GCAGTCCCTG 
CCCCCCGGTT TGGCAGTGAA GGAACTGAAA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural snapshots of actively translating human ribosomes.
Cell161(4)845-57(2015 May)
Behrmann E,Loerke J,Budkevich TV,Yamamoto K,Schmidt A,Penczek PA,Vos MR,B?rger J,Mielke T,Scheerer P,Spahn CM

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
Nature cell biology13(4)383-93(2011 Apr)
Kuo JC,Han X,Hsiao CT,Yates JR 3rd,Waterman CM

Characterization of the proteome, diseases and evolution of the human postsynaptic density.
Nature neuroscience14(1)19-21(2011 Jan)
Bay?s A,van de Lagemaat LN,Collins MO,Croning MD,Whittle IR,Choudhary JS,Grant SG

A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.
Genomics88(3)333-46(2006 Sep)
Tsang HT,Connell JW,Brown SE,Thompson A,Reid E,Sanderson CM

Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)
Wang AG,Yoon SY,Oh JH,Jeon YJ,Kim M,Kim JM,Byun SS,Yang JO,Kim JH,Kim DG,Yeom YI,Yoo HS,Kim YS,Kim NS

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RPL38 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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