RPL24 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPL24
Entrez Gene ID	6152
Full Name	ribosomal protein L24
Synonyms	HEL-S-310,L24
General protein information	Preferred Names ribosomal protein L24 Names 60S ribosomal protein L24 60S ribosomal protein L30 epididymis secretory protein Li 310 large ribosomal subunit protein eL24 ribosomal protein L30
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q12.3
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from S. cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
Disorder MIM:	604180

mRNA and Protein(s)

mRNA	Protein	Name
NM_000986.3	NP_000977.1	60S ribosomal protein L24
NM_000986.4	NP_000977.1	60S ribosomal protein L24

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RPL24	XP_005639487.1
Eremothecium gossypii	AGOS_AFR477C	NP_986024.1
Oryza sativa (rice)	Os01g0815800	NP_001044615.1
	RPL24	XP_001098207.1
Rattus norvegicus (Norway rat)	Rpl24	NP_071960.1
Magnaporthe oryzae (rice blast fungus)	MGG_02711	XP_003721049.1
Oryza sativa (rice)	Os05g0486700	NP_001055880.1
Drosophila melanogaster (fruit fly)	RpL24	NP_609649.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010216	XP_319401.2
Caenorhabditis elegans (roundworm)	rpl-24.1	NP_491399.1
Arabidopsis thaliana (thale cress)	STV1	NP_190870.1
Pan troglodytes (chimpanzee)	RPL24	XP_001148458.1
Gallus gallus (chicken)	RPL24	XP_416616.2
Danio rerio (zebrafish)	rpl24	NP_775342.1
Saccharomyces cerevisiae (baker's yeast)	RPL24A	NP_011484.1
Kluyveromyces lactis	KLLA0E10869g	XP_454440.1
Schizosaccharomyces pombe (fission yeast)	rpl2401	NP_594118.1
Schizosaccharomyces pombe (fission yeast)	rpl2402	NP_587714.1
Oryza sativa (rice)	Os07g0224000	NP_001059209.2
Xenopus tropicalis (tropical clawed frog)	rpl24	NP_001017041.1
Homo sapiens (human)	RPL24	NP_000977.1
Bos taurus (cattle)	RPL24	NP_776880.1
Mus musculus (house mouse)	Rpl24	NP_077180.1
Saccharomyces cerevisiae (baker's yeast)	RPL24B	NP_011664.3
Neurospora crassa	NCU03150	XP_964199.1
Arabidopsis thaliana (thale cress)	RPL24A	NP_565851.1

Gene Ontology
Bibliography

Related articles in PubMed

Structural snapshots of actively translating human ribosomes.
Behrmann E, Loerke J, Budkevich TV, Yamamoto K, Schmidt A, Penczek PA, Vos MR, B?rger J, Mielke T, Scheerer P, Spahn CM
Cell161(4)845-57(2015 May)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.
Wilson-Edell KA, Kehasse A, Scott GK, Yau C, Rothschild DE, Schilling B, Gabriel BS, Yevtushenko MA, Hanson IM, Held JM, Gibson BW, Benz CC
Oncotarget5(13)5165-76(2014 Jul)

Drug resistance effects of ribosomal protein L24 overexpression in hepatocellular carcinoma HepG2 cells.
Guo YL, Kong QS, Liu HS, Tan WB
Asian Pacific journal of cancer prevention : APJCP15(22)9853-7(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that ribosomal subunit protein 24 (RPL24) lysine K27 acetylation may play a role in ribosome assembly.
Title: RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.

Ribosomal protein L24 overexpression in hepatocellular carcinoma.
Title: Drug resistance effects of ribosomal protein L24 overexpression in hepatocellular carcinoma HepG2 cells.

The following RPL24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPL24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02100	NM_000986.4 Latest version!	Homo sapiens ribosomal protein L24 (RPL24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu02100	NM_000986.3	Homo sapiens ribosomal protein L24 (RPL24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPL24 ( NM_000986.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000977.1 Homo sapiens ribosomal protein L24 (RPL24), mRNA.

Price & Availability↑

CloneID	OHu02100
Clone ID Related Accession (Same CDS sequence)	NM_000986.3 , NM_000986.4
Accession Version	NM_000986.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	60S ribosomal protein L24
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BU754101.1, M94314.1 and CD513036.1. On Oct 27, 2005 this sequence version replaced NM_000986.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP272221.1, SRR1163657.273577.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAAGGTCG AGCTGTGCAG TTTTAGCGGG TACAAGATCT ACCCCGGACA CGGGAGGCGC 
TACGCCAGGA CCGACGGGAA GGTTTTCCAG TTTCTTAATG CGAAATGCGA GTCGGCTTTC 
CTTTCCAAGA GGAATCCTCG GCAGATAAAC TGGACTGTCC TCTACAGAAG GAAGCACAAA 
AAGGGACAGT CGGAAGAAAT TCAAAAGAAA AGAACCCGCC GAGCAGTCAA ATTCCAGAGG 
GCCATTACTG GTGCATCTCT TGCTGATATA ATGGCCAAGA GGAATCAGAA ACCTGAAGTT 
AGAAAGGCTC AACGAGAACA AGCTATCAGG GCTGCTAAGG AAGCAAAAAA GGCTAAGCAA 
GCATCTAAAA AGACTGCAAT GGCTGCTGCT AAGGCACCTA CAAAGGCAGC ACCTAAGCAA 
AAGATTGTGA AGCCTGTGAA AGTTTCAGCT CCCCGAGTTG GTGGAAAACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000977.1
CDS	44..517
Translation	MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR

Target ORF information:

RefSeq Version	NM_000986.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L24 (RPL24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000986.3

ORF Insert Sequence:

ATGAAGGTCG AGCTGTGCAG TTTTAGCGGG TACAAGATCT ACCCCGGACA CGGGAGGCGC 
TACGCCAGGA CCGACGGGAA GGTTTTCCAG TTTCTTAATG CGAAATGCGA GTCGGCTTTC 
CTTTCCAAGA GGAATCCTCG GCAGATAAAC TGGACTGTCC TCTACAGAAG GAAGCACAAA 
AAGGGACAGT CGGAAGAAAT TCAAAAGAAA AGAACCCGCC GAGCAGTCAA ATTCCAGAGG 
GCCATTACTG GTGCATCTCT TGCTGATATA ATGGCCAAGA GGAATCAGAA ACCTGAAGTT 
AGAAAGGCTC AACGAGAACA AGCTATCAGG GCTGCTAAGG AAGCAAAAAA GGCTAAGCAA 
GCATCTAAAA AGACTGCAAT GGCTGCTGCT AAGGCACCTA CAAAGGCAGC ACCTAAGCAA 
AAGATTGTGA AGCCTGTGAA AGTTTCAGCT CCCCGAGTTG GTGGAAAACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL24 ( NM_000986.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000977.1 Homo sapiens ribosomal protein L24 (RPL24), mRNA.

Price & Availability↑

CloneID	OHu02100
Clone ID Related Accession (Same CDS sequence)	NM_000986.3 , NM_000986.4
Accession Version	NM_000986.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 474bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	60S ribosomal protein L24
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BU754101.1, M94314.1 and CD513036.1. On Nov 22, 2018 this sequence version replaced NM_000986.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM772472.1, BM997631.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000394077.8/ ENSP00000377640.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGGTCG AGCTGTGCAG TTTTAGCGGG TACAAGATCT ACCCCGGACA CGGGAGGCGC 
TACGCCAGGA CCGACGGGAA GGTTTTCCAG TTTCTTAATG CGAAATGCGA GTCGGCTTTC 
CTTTCCAAGA GGAATCCTCG GCAGATAAAC TGGACTGTCC TCTACAGAAG GAAGCACAAA 
AAGGGACAGT CGGAAGAAAT TCAAAAGAAA AGAACCCGCC GAGCAGTCAA ATTCCAGAGG 
GCCATTACTG GTGCATCTCT TGCTGATATA ATGGCCAAGA GGAATCAGAA ACCTGAAGTT 
AGAAAGGCTC AACGAGAACA AGCTATCAGG GCTGCTAAGG AAGCAAAAAA GGCTAAGCAA 
GCATCTAAAA AGACTGCAAT GGCTGCTGCT AAGGCACCTA CAAAGGCAGC ACCTAAGCAA 
AAGATTGTGA AGCCTGTGAA AGTTTCAGCT CCCCGAGTTG GTGGAAAACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000977.1
CDS	43..516
Translation	MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR

Target ORF information:

RefSeq Version	NM_000986.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L24 (RPL24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000986.4

ORF Insert Sequence:

ATGAAGGTCG AGCTGTGCAG TTTTAGCGGG TACAAGATCT ACCCCGGACA CGGGAGGCGC 
TACGCCAGGA CCGACGGGAA GGTTTTCCAG TTTCTTAATG CGAAATGCGA GTCGGCTTTC 
CTTTCCAAGA GGAATCCTCG GCAGATAAAC TGGACTGTCC TCTACAGAAG GAAGCACAAA 
AAGGGACAGT CGGAAGAAAT TCAAAAGAAA AGAACCCGCC GAGCAGTCAA ATTCCAGAGG 
GCCATTACTG GTGCATCTCT TGCTGATATA ATGGCCAAGA GGAATCAGAA ACCTGAAGTT 
AGAAAGGCTC AACGAGAACA AGCTATCAGG GCTGCTAAGG AAGCAAAAAA GGCTAAGCAA 
GCATCTAAAA AGACTGCAAT GGCTGCTGCT AAGGCACCTA CAAAGGCAGC ACCTAAGCAA 
AAGATTGTGA AGCCTGTGAA AGTTTCAGCT CCCCGAGTTG GTGGAAAACG CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural snapshots of actively translating human ribosomes.
Cell161(4)845-57(2015 May)
Behrmann E,Loerke J,Budkevich TV,Yamamoto K,Schmidt A,Penczek PA,Vos MR,B?rger J,Mielke T,Scheerer P,Spahn CM

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.
Oncotarget5(13)5165-76(2014 Jul)
Wilson-Edell KA,Kehasse A,Scott GK,Yau C,Rothschild DE,Schilling B,Gabriel BS,Yevtushenko MA,Hanson IM,Held JM,Gibson BW,Benz CC

Drug resistance effects of ribosomal protein L24 overexpression in hepatocellular carcinoma HepG2 cells.
Asian Pacific journal of cancer prevention : APJCP15(22)9853-7(2014)
Guo YL,Kong QS,Liu HS,Tan WB

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RPL24 cDNA ORF clone, Homo sapiens(human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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