RPL23A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPL23A
Entrez Gene ID	6147
Full Name	ribosomal protein L23a
Synonyms	L23A,MDA20
General protein information	Preferred Names ribosomal protein L23a Names 60S ribosomal protein L23a large ribosomal subunit protein uL23 melanoma differentiation-associated gene 20
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q11.2
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L23P family of ribosomal proteins. It is located in the cytoplasm. The protein may be one of the target molecules involved in mediating growth inhibition by interferon. In yeast, the corresponding protein binds to a specific site on the 26S rRNA. This gene is co-transcribed with the U42A, U42B, U101A, and U101B small nucleolar RNA genes, which are located in its third, first, second, and fourth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
Disorder MIM:	602326

mRNA and Protein(s)

mRNA	Protein	Name
NM_000984.5	NP_000975.2	60S ribosomal protein L23a
NM_000984.6	NP_000975.2	60S ribosomal protein L23a

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC742934	XP_001159035.1
Pan troglodytes (chimpanzee)	RPL23A	XP_001144156.1
	RPL23A	XP_001109700.1
Homo sapiens (human)	RPL23A	NP_000975.2
Bos taurus (cattle)	RPL23A	NP_001039423.1
	LOC718737	XP_001111837.1
	LOC706606	XP_002798761.1
Canis lupus familiaris (dog)	LOC610129	XP_852639.1
Rattus norvegicus (Norway rat)	RGD1564606	XP_006231970.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006037	XP_316083.3

Gene Ontology
Bibliography

Related articles in PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, Dawson TM, Dawson VL
Cell157(2)472-485(2014 Apr)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RPL23A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPL23A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30069	NM_000984.6 Latest version!	Homo sapiens ribosomal protein L23a (RPL23A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu30069	NM_000984.5	Homo sapiens ribosomal protein L23a (RPL23A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPL23A ( NM_000984.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000975.2 Homo sapiens ribosomal protein L23a (RPL23A), mRNA.

Price & Availability↑

CloneID	OHu30069
Clone ID Related Accession (Same CDS sequence)	NM_000984.5 , NM_000984.6
Accession Version	NM_000984.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 471bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	60S ribosomal protein L23a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BP382007.1, U43701.1, BC058041.1 and BE464375.1. On Oct 27, 2005 this sequence version replaced NM_000984.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.187195.1, BC058041.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCGCCGA AAGCGAAGAA GGAAGCTCCT GCCCCTCCTA AAGCTGAAGC CAAAGCGAAG 
GCTTTAAAGG CCAAGAAGGC AGTGTTGAAA GGTGTCCACA GCCACAAAAA GAAGAAGATC 
CGCACGTCAC CCACCTTCCG GCGGCCGAAG ACACTGCGAC TCCGGAGACA GCCCAAATAT 
CCTCGGAAGA GCGCTCCCAG GAGAAACAAG CTTGACCACT ATGCTATCAT CAAGTTTCCG 
CTGACCACTG AGTCTGCCAT GAAGAAGATA GAAGACAACA ACACACTTGT GTTCATTGTG 
GATGTTAAAG CCAACAAGCA CCAGATTAAA CAGGCTGTGA AGAAGCTGTA TGACATTGAT 
GTGGCCAAGG TCAACACCCT GATTCGGCCT GATGGAGAGA AGAAGGCATA TGTTCGACTG 
GCTCCTGATT ACGATGCTTT GGATGTTGCC AACAAAATTG GGATCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000975.2
CDS	25..495
Translation	MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

Target ORF information:

RefSeq Version	NM_000984.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L23a (RPL23A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000984.5

ORF Insert Sequence:

ATGGCGCCGA AAGCGAAGAA GGAAGCTCCT GCCCCTCCTA AAGCTGAAGC CAAAGCGAAG 
GCTTTAAAGG CCAAGAAGGC AGTGTTGAAA GGTGTCCACA GCCACAAAAA GAAGAAGATC 
CGCACGTCAC CCACCTTCCG GCGGCCGAAG ACACTGCGAC TCCGGAGACA GCCCAAATAT 
CCTCGGAAGA GCGCTCCCAG GAGAAACAAG CTTGACCACT ATGCTATCAT CAAGTTTCCG 
CTGACCACTG AGTCTGCCAT GAAGAAGATA GAAGACAACA ACACACTTGT GTTCATTGTG 
GATGTTAAAG CCAACAAGCA CCAGATTAAA CAGGCTGTGA AGAAGCTGTA TGACATTGAT 
GTGGCCAAGG TCAACACCCT GATTCGGCCT GATGGAGAGA AGAAGGCATA TGTTCGACTG 
GCTCCTGATT ACGATGCTTT GGATGTTGCC AACAAAATTG GGATCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RPL23A ( NM_000984.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_000975.2 Homo sapiens ribosomal protein L23a (RPL23A), mRNA.

Price & Availability↑

CloneID	OHu30069
Clone ID Related Accession (Same CDS sequence)	NM_000984.5 , NM_000984.6
Accession Version	NM_000984.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 471bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	60S ribosomal protein L23a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from U43701.1, BC058041.1, BE464375.1 and AC010761.10. On Nov 22, 2018 this sequence version replaced NM_000984.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189658.26679.1, SRR5189661.13134.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000422514.7/ ENSP00000389103.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGCCGA AAGCGAAGAA GGAAGCTCCT GCCCCTCCTA AAGCTGAAGC CAAAGCGAAG 
GCTTTAAAGG CCAAGAAGGC AGTGTTGAAA GGTGTCCACA GCCACAAAAA GAAGAAGATC 
CGCACGTCAC CCACCTTCCG GCGGCCGAAG ACACTGCGAC TCCGGAGACA GCCCAAATAT 
CCTCGGAAGA GCGCTCCCAG GAGAAACAAG CTTGACCACT ATGCTATCAT CAAGTTTCCG 
CTGACCACTG AGTCTGCCAT GAAGAAGATA GAAGACAACA ACACACTTGT GTTCATTGTG 
GATGTTAAAG CCAACAAGCA CCAGATTAAA CAGGCTGTGA AGAAGCTGTA TGACATTGAT 
GTGGCCAAGG TCAACACCCT GATTCGGCCT GATGGAGAGA AGAAGGCATA TGTTCGACTG 
GCTCCTGATT ACGATGCTTT GGATGTTGCC AACAAAATTG GGATCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000975.2
CDS	22..492
Translation	MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII

Target ORF information:

RefSeq Version	NM_000984.6
Organism	Homo sapiens(human)
Definition	Homo sapiens ribosomal protein L23a (RPL23A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000984.6

ORF Insert Sequence:

ATGGCGCCGA AAGCGAAGAA GGAAGCTCCT GCCCCTCCTA AAGCTGAAGC CAAAGCGAAG 
GCTTTAAAGG CCAAGAAGGC AGTGTTGAAA GGTGTCCACA GCCACAAAAA GAAGAAGATC 
CGCACGTCAC CCACCTTCCG GCGGCCGAAG ACACTGCGAC TCCGGAGACA GCCCAAATAT 
CCTCGGAAGA GCGCTCCCAG GAGAAACAAG CTTGACCACT ATGCTATCAT CAAGTTTCCG 
CTGACCACTG AGTCTGCCAT GAAGAAGATA GAAGACAACA ACACACTTGT GTTCATTGTG 
GATGTTAAAG CCAACAAGCA CCAGATTAAA CAGGCTGTGA AGAAGCTGTA TGACATTGAT 
GTGGCCAAGG TCAACACCCT GATTCGGCCT GATGGAGAGA AGAAGGCATA TGTTCGACTG 
GCTCCTGATT ACGATGCTTT GGATGTTGCC AACAAAATTG GGATCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
Cell157(2)472-485(2014 Apr)
Martin I,Kim JW,Lee BD,Kang HC,Xu JC,Jia H,Stankowski J,Kim MS,Zhong J,Kumar M,Andrabi SA,Xiong Y,Dickson DW,Wszolek ZK,Pandey A,Dawson TM,Dawson VL

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

RPL23A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報