BCR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BCR
Entrez Gene ID	613
Full Name	BCR, RhoGEF and GTPase activating protein
Synonyms	ALL,BCR1,CML,D22S11,D22S662,PHL
General protein information	Preferred Names BCR, RhoGEF and GTPase activating protein Names breakpoint cluster region protein BCR/FGFR1 chimera protein FGFR1/BCR chimera protein breakpoint cluster region renal carcinoma antigen NY-REN-26
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q11.23
Summary	A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	151410
Disorder Html:	Leukemia, chronic myeloid, somatic, 608232 (3); Leukemia, acute lymphocytic, somatic, 613065 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_021574.2	NP_067585.2	breakpoint cluster region protein isoform 2
NM_021574.3	NP_067585.2	breakpoint cluster region protein isoform 2
NM_004327.3	NP_004318.3	breakpoint cluster region protein isoform 1
NM_004327.4	NP_004318.3	breakpoint cluster region protein isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	BCR	NP_004318.3
Canis lupus familiaris (dog)	BCR	XP_848654.2
Pan troglodytes (chimpanzee)	BCR	XP_003317181.1
	BCR	XP_002798337.1
Gallus gallus (chicken)	BCR	XP_415244.3
Mus musculus (house mouse)	Bcr	NP_001074881.1
Danio rerio (zebrafish)	bcr	XP_005161278.1
Xenopus tropicalis (tropical clawed frog)	bcr	NP_001123792.1
Rattus norvegicus (Norway rat)	Bcr	XP_228091.6

Gene Ontology

The following BCR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BCR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25516	NM_021574.3 Latest version!	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
OHu25583	NM_004327.4 Latest version!	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$895.30 $1279.00
View Old Accession Versions >>
OHu25516	NM_021574.2	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$643.30 $919.00
OHu25583	NM_004327.3	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$895.30 $1279.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BCR ( NM_021574.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_067585.2 Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25516
Clone ID Related Accession (Same CDS sequence)	NM_021574.2 , NM_021574.3
Accession Version	NM_021574.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	breakpoint cluster region protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U07000.1, BC066122.1, BQ422888.1 and Y00661.1. On or before Mar 15, 2007 this sequence version replaced XM_001131266.1, NM_021574.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y00661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
CTGGACCCGC AGGCCCTGCA GGACAGAGAC TGGCAGCGCA CCGTCATCGC CATGAATGGG 
ATCGAAGTAA AGCTCTCGGT CAAGTTCAAC AGCAGGGAGT TCAGCTTGAA GAGGATGCCG 
TCCCGAAAAC AGACAGGGGT CTTCGGAGTC AAGATTGCTG TGGTCACCAA GAGAGAGAGG 
TCCAAGGTGC CCTACATCGT GCGCCAGTGC GTGGAGGAGA TCGAGCGCCG AGGCATGGAG 
GAGGTGGGCA TCTACCGCGT GTCCGGTGTG GCCACGGACA TCCAGGCACT GAAGGCAGCC 
TTCGACGTCA ATAACAAGGA CGTGTCGGTG ATGATGAGCG AGATGGACGT GAACGCCATC 
GCAGGCACGC TGAAGCTGTA CTTCCGTGAG CTGCCCGAGC CCCTCTTCAC TGACGAGTTC 
TACCCCAACT TCGCAGAGGG CATCGCTCTT TCAGACCCGG TTGCAAAGGA GAGCTGCATG 
CTCAACCTGC TGCTGTCCCT GCCGGAGGCC AACCTGCTCA CCTTCCTTTT CCTTCTGGAC 
CACCTGAAAA GGGTGGCAGA GAAGGAGGCA GTCAATAAGA TGTCCCTGCA CAACCTCGCC 
ACGGTCTTTG GCCCCACGCT GCTCCGGCCC TCCGAGAAGG AGAGCAAGCT CCCTGCCAAC 
CCCAGCCAGC CTATCACCAT GACTGACAGC TGGTCCTTGG AGGTCATGTC CCAGGTCCAG 
GTGCTGCTGT ACTTCCTGCA GCTGGAGGCC ATCCCTGCCC CGGACAGCAA GAGACAGAGC 
ATCCTGTTCT CCACCGAAGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067585.2
CDS	597..4280
Translation	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNELDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV

Target ORF information:

RefSeq Version	NM_021574.2
Organism	Homo sapiens(human)
Definition	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021574.2

ORF Insert Sequence:

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
CTGGACCCGC AGGCCCTGCA GGACAGAGAC TGGCAGCGCA CCGTCATCGC CATGAATGGG 
ATCGAAGTAA AGCTCTCGGT CAAGTTCAAC AGCAGGGAGT TCAGCTTGAA GAGGATGCCG 
TCCCGAAAAC AGACAGGGGT CTTCGGAGTC AAGATTGCTG TGGTCACCAA GAGAGAGAGG 
TCCAAGGTGC CCTACATCGT GCGCCAGTGC GTGGAGGAGA TCGAGCGCCG AGGCATGGAG 
GAGGTGGGCA TCTACCGCGT GTCCGGTGTG GCCACGGACA TCCAGGCACT GAAGGCAGCC 
TTCGACGTCA ATAACAAGGA CGTGTCGGTG ATGATGAGCG AGATGGACGT GAACGCCATC 
GCAGGCACGC TGAAGCTGTA CTTCCGTGAG CTGCCCGAGC CCCTCTTCAC TGACGAGTTC 
TACCCCAACT TCGCAGAGGG CATCGCTCTT TCAGACCCGG TTGCAAAGGA GAGCTGCATG 
CTCAACCTGC TGCTGTCCCT GCCGGAGGCC AACCTGCTCA CCTTCCTTTT CCTTCTGGAC 
CACCTGAAAA GGGTGGCAGA GAAGGAGGCA GTCAATAAGA TGTCCCTGCA CAACCTCGCC 
ACGGTCTTTG GCCCCACGCT GCTCCGGCCC TCCGAGAAGG AGAGCAAGCT CCCTGCCAAC 
CCCAGCCAGC CTATCACCAT GACTGACAGC TGGTCCTTGG AGGTCATGTC CCAGGTCCAG 
GTGCTGCTGT ACTTCCTGCA GCTGGAGGCC ATCCCTGCCC CGGACAGCAA GAGACAGAGC 
ATCCTGTTCT CCACCGAAGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCR ( NM_021574.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067585.2 Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25516
Clone ID Related Accession (Same CDS sequence)	NM_021574.2 , NM_021574.3
Accession Version	NM_021574.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-02
Organism	Homo sapiens(human)
Product	breakpoint cluster region protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U07000.1, BC066122.1, BQ422888.1 and Y00661.1. On May 31, 2019 this sequence version replaced NM_021574.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y00661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
CTGGACCCGC AGGCCCTGCA GGACAGAGAC TGGCAGCGCA CCGTCATCGC CATGAATGGG 
ATCGAAGTAA AGCTCTCGGT CAAGTTCAAC AGCAGGGAGT TCAGCTTGAA GAGGATGCCG 
TCCCGAAAAC AGACAGGGGT CTTCGGAGTC AAGATTGCTG TGGTCACCAA GAGAGAGAGG 
TCCAAGGTGC CCTACATCGT GCGCCAGTGC GTGGAGGAGA TCGAGCGCCG AGGCATGGAG 
GAGGTGGGCA TCTACCGCGT GTCCGGTGTG GCCACGGACA TCCAGGCACT GAAGGCAGCC 
TTCGACGTCA ATAACAAGGA CGTGTCGGTG ATGATGAGCG AGATGGACGT GAACGCCATC 
GCAGGCACGC TGAAGCTGTA CTTCCGTGAG CTGCCCGAGC CCCTCTTCAC TGACGAGTTC 
TACCCCAACT TCGCAGAGGG CATCGCTCTT TCAGACCCGG TTGCAAAGGA GAGCTGCATG 
CTCAACCTGC TGCTGTCCCT GCCGGAGGCC AACCTGCTCA CCTTCCTTTT CCTTCTGGAC 
CACCTGAAAA GGGTGGCAGA GAAGGAGGCA GTCAATAAGA TGTCCCTGCA CAACCTCGCC 
ACGGTCTTTG GCCCCACGCT GCTCCGGCCC TCCGAGAAGG AGAGCAAGCT CCCTGCCAAC 
CCCAGCCAGC CTATCACCAT GACTGACAGC TGGTCCTTGG AGGTCATGTC CCAGGTCCAG 
GTGCTGCTGT ACTTCCTGCA GCTGGAGGCC ATCCCTGCCC CGGACAGCAA GAGACAGAGC 
ATCCTGTTCT CCACCGAAGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067585.2
CDS	453..4136
Translation	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNELDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV

Target ORF information:

RefSeq Version	NM_021574.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021574.3

ORF Insert Sequence:

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
CTGGACCCGC AGGCCCTGCA GGACAGAGAC TGGCAGCGCA CCGTCATCGC CATGAATGGG 
ATCGAAGTAA AGCTCTCGGT CAAGTTCAAC AGCAGGGAGT TCAGCTTGAA GAGGATGCCG 
TCCCGAAAAC AGACAGGGGT CTTCGGAGTC AAGATTGCTG TGGTCACCAA GAGAGAGAGG 
TCCAAGGTGC CCTACATCGT GCGCCAGTGC GTGGAGGAGA TCGAGCGCCG AGGCATGGAG 
GAGGTGGGCA TCTACCGCGT GTCCGGTGTG GCCACGGACA TCCAGGCACT GAAGGCAGCC 
TTCGACGTCA ATAACAAGGA CGTGTCGGTG ATGATGAGCG AGATGGACGT GAACGCCATC 
GCAGGCACGC TGAAGCTGTA CTTCCGTGAG CTGCCCGAGC CCCTCTTCAC TGACGAGTTC 
TACCCCAACT TCGCAGAGGG CATCGCTCTT TCAGACCCGG TTGCAAAGGA GAGCTGCATG 
CTCAACCTGC TGCTGTCCCT GCCGGAGGCC AACCTGCTCA CCTTCCTTTT CCTTCTGGAC 
CACCTGAAAA GGGTGGCAGA GAAGGAGGCA GTCAATAAGA TGTCCCTGCA CAACCTCGCC 
ACGGTCTTTG GCCCCACGCT GCTCCGGCCC TCCGAGAAGG AGAGCAAGCT CCCTGCCAAC 
CCCAGCCAGC CTATCACCAT GACTGACAGC TGGTCCTTGG AGGTCATGTC CCAGGTCCAG 
GTGCTGCTGT ACTTCCTGCA GCTGGAGGCC ATCCCTGCCC CGGACAGCAA GAGACAGAGC 
ATCCTGTTCT CCACCGAAGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCR ( NM_004327.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004318.3 Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 1, mRNA.

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CloneID	OHu25583
Clone ID Related Accession (Same CDS sequence)	NM_004327.3 , NM_004327.4
Accession Version	NM_004327.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	breakpoint cluster region protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U07000.1, BC066122.1, BQ422888.1 and X02596.1. This sequence is a reference standard in the RefSeqGene project. On Nov 18, 2005 this sequence version replaced NM_004327.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.226032.1, X02596.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
GAATTTGAGA TAGAGCTGGA GGGCTCCCAG ACCCTGAGGA TACTGTGCTA TGAAAAGTGT 
TACAACAAGA CGAAGATCCC CAAGGAGGAC GGCGAGAGCA CGGACAGACT CATGGGGAAG 
GGCCAGGTCC AGCTGGACCC GCAGGCCCTG CAGGACAGAG ACTGGCAGCG CACCGTCATC 
GCCATGAATG GGATCGAAGT AAAGCTCTCG GTCAAGTTCA ACAGCAGGGA GTTCAGCTTG 
AAGAGGATGC CGTCCCGAAA ACAGACAGGG GTCTTCGGAG TCAAGATTGC TGTGGTCACC 
AAGAGAGAGA GGTCCAAGGT GCCCTACATC GTGCGCCAGT GCGTGGAGGA GATCGAGCGC 
CGAGGCATGG AGGAGGTGGG CATCTACCGC GTGTCCGGTG TGGCCACGGA CATCCAGGCA 
CTGAAGGCAG CCTTCGACGT CAATAACAAG GACGTGTCGG TGATGATGAG CGAGATGGAC 
GTGAACGCCA TCGCAGGCAC GCTGAAGCTG TACTTCCGTG AGCTGCCCGA GCCCCTCTTC 
ACTGACGAGT TCTACCCCAA CTTCGCAGAG GGCATCGCTC TTTCAGACCC GGTTGCAAAG 
GAGAGCTGCA TGCTCAACCT GCTGCTGTCC CTGCCGGAGG CCAACCTGCT CACCTTCCTT 
TTCCTTCTGG ACCACCTGAA AAGGGTGGCA GAGAAGGAGG CAGTCAATAA GATGTCCCTG 
CACAACCTCG CCACGGTCTT TGGCCCCACG CTGCTCCGGC CCTCCGAGAA GGAGAGCAAG 
CTCCCTGCCA ACCCCAGCCA GCCTATCACC ATGACTGACA GCTGGTCCTT GGAGGTCATG 
TCCCAGGTCC AGGTGCTGCT GTACTTCCTG CAGCTGGAGG CCATCCCTGC CCCGGACAGC 
AAGAGACAGA GCATCCTGTT CTCCACCGAA GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004318.3
CDS	597..4412
Translation	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV

Target ORF information:

RefSeq Version	NM_004327.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004327.3

ORF Insert Sequence:

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
GAATTTGAGA TAGAGCTGGA GGGCTCCCAG ACCCTGAGGA TACTGTGCTA TGAAAAGTGT 
TACAACAAGA CGAAGATCCC CAAGGAGGAC GGCGAGAGCA CGGACAGACT CATGGGGAAG 
GGCCAGGTCC AGCTGGACCC GCAGGCCCTG CAGGACAGAG ACTGGCAGCG CACCGTCATC 
GCCATGAATG GGATCGAAGT AAAGCTCTCG GTCAAGTTCA ACAGCAGGGA GTTCAGCTTG 
AAGAGGATGC CGTCCCGAAA ACAGACAGGG GTCTTCGGAG TCAAGATTGC TGTGGTCACC 
AAGAGAGAGA GGTCCAAGGT GCCCTACATC GTGCGCCAGT GCGTGGAGGA GATCGAGCGC 
CGAGGCATGG AGGAGGTGGG CATCTACCGC GTGTCCGGTG TGGCCACGGA CATCCAGGCA 
CTGAAGGCAG CCTTCGACGT CAATAACAAG GACGTGTCGG TGATGATGAG CGAGATGGAC 
GTGAACGCCA TCGCAGGCAC GCTGAAGCTG TACTTCCGTG AGCTGCCCGA GCCCCTCTTC 
ACTGACGAGT TCTACCCCAA CTTCGCAGAG GGCATCGCTC TTTCAGACCC GGTTGCAAAG 
GAGAGCTGCA TGCTCAACCT GCTGCTGTCC CTGCCGGAGG CCAACCTGCT CACCTTCCTT 
TTCCTTCTGG ACCACCTGAA AAGGGTGGCA GAGAAGGAGG CAGTCAATAA GATGTCCCTG 
CACAACCTCG CCACGGTCTT TGGCCCCACG CTGCTCCGGC CCTCCGAGAA GGAGAGCAAG 
CTCCCTGCCA ACCCCAGCCA GCCTATCACC ATGACTGACA GCTGGTCCTT GGAGGTCATG 
TCCCAGGTCC AGGTGCTGCT GTACTTCCTG CAGCTGGAGG CCATCCCTGC CCCGGACAGC 
AAGAGACAGA GCATCCTGTT CTCCACCGAA GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCR ( NM_004327.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004318.3 Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 1, mRNA.

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CloneID	OHu25583
Clone ID Related Accession (Same CDS sequence)	NM_004327.3 , NM_004327.4
Accession Version	NM_004327.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3816bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-02
Organism	Homo sapiens(human)
Product	breakpoint cluster region protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U07000.1, BC066122.1, BQ422888.1 and X02596.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_004327.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.226032.1, BC066122.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000305877.13/ ENSP00000303507.8 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
GAATTTGAGA TAGAGCTGGA GGGCTCCCAG ACCCTGAGGA TACTGTGCTA TGAAAAGTGT 
TACAACAAGA CGAAGATCCC CAAGGAGGAC GGCGAGAGCA CGGACAGACT CATGGGGAAG 
GGCCAGGTCC AGCTGGACCC GCAGGCCCTG CAGGACAGAG ACTGGCAGCG CACCGTCATC 
GCCATGAATG GGATCGAAGT AAAGCTCTCG GTCAAGTTCA ACAGCAGGGA GTTCAGCTTG 
AAGAGGATGC CGTCCCGAAA ACAGACAGGG GTCTTCGGAG TCAAGATTGC TGTGGTCACC 
AAGAGAGAGA GGTCCAAGGT GCCCTACATC GTGCGCCAGT GCGTGGAGGA GATCGAGCGC 
CGAGGCATGG AGGAGGTGGG CATCTACCGC GTGTCCGGTG TGGCCACGGA CATCCAGGCA 
CTGAAGGCAG CCTTCGACGT CAATAACAAG GACGTGTCGG TGATGATGAG CGAGATGGAC 
GTGAACGCCA TCGCAGGCAC GCTGAAGCTG TACTTCCGTG AGCTGCCCGA GCCCCTCTTC 
ACTGACGAGT TCTACCCCAA CTTCGCAGAG GGCATCGCTC TTTCAGACCC GGTTGCAAAG 
GAGAGCTGCA TGCTCAACCT GCTGCTGTCC CTGCCGGAGG CCAACCTGCT CACCTTCCTT 
TTCCTTCTGG ACCACCTGAA AAGGGTGGCA GAGAAGGAGG CAGTCAATAA GATGTCCCTG 
CACAACCTCG CCACGGTCTT TGGCCCCACG CTGCTCCGGC CCTCCGAGAA GGAGAGCAAG 
CTCCCTGCCA ACCCCAGCCA GCCTATCACC ATGACTGACA GCTGGTCCTT GGAGGTCATG 
TCCCAGGTCC AGGTGCTGCT GTACTTCCTG CAGCTGGAGG CCATCCCTGC CCCGGACAGC 
AAGAGACAGA GCATCCTGTT CTCCACCGAA GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004318.3
CDS	453..4268
Translation	MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQTLLAKEKKSYDRQRWGFRRAAQAPDGASEPRASASRPQPAPADGADPPPAEEPEARPDGEGSPGKARPGTARRPGAAASGERDDRGPPASVAALRSNFERIRKGHGQPGADAEKPFYVNVEFHHERGLVKVNDKEVSDRISSLGSQAMQMERKKSQHGAGSSVGDASRPPYRGRSSESSCGVDGDYEDAELNPRFLKDNLIDANGGSRPPWPPLEYQPYQSIYVGGMMEGEGKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDCGGGYTPDCSSNENLTSSEEDFSSGQSSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRHCPVVVSEATIVGVRKTGQIWPNDGEGAFHGDADGSFGTPPGYGCAADRAEEQRRHQDGLPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEITPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRSFSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDGESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGVFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV

Target ORF information:

RefSeq Version	NM_004327.4
Organism	Homo sapiens(human)
Definition	Homo sapiens BCR activator of RhoGEF and GTPase (BCR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004327.4

ORF Insert Sequence:

ATGGTGGACC CGGTGGGCTT CGCGGAGGCG TGGAAGGCGC AGTTCCCGGA CTCAGAGCCC 
CCGCGCATGG AGCTGCGCTC AGTGGGCGAC ATCGAGCAGG AGCTGGAGCG CTGCAAGGCC 
TCCATTCGGC GCCTGGAGCA GGAGGTGAAC CAGGAGCGCT TCCGCATGAT CTACCTGCAG 
ACGTTGCTGG CCAAGGAAAA GAAGAGCTAT GACCGGCAGC GATGGGGCTT CCGGCGCGCG 
GCGCAGGCCC CCGACGGCGC CTCCGAGCCC CGAGCGTCCG CGTCGCGCCC GCAGCCAGCG 
CCCGCCGACG GAGCCGACCC GCCGCCCGCC GAGGAGCCCG AGGCCCGGCC CGACGGCGAG 
GGTTCTCCGG GTAAGGCCAG GCCCGGGACC GCCCGCAGGC CCGGGGCAGC CGCGTCGGGG 
GAACGGGACG ACCGGGGACC CCCCGCCAGC GTGGCGGCGC TCAGGTCCAA CTTCGAGCGG 
ATCCGCAAGG GCCATGGCCA GCCCGGGGCG GACGCCGAGA AGCCCTTCTA CGTGAACGTC 
GAGTTTCACC ACGAGCGCGG CCTGGTGAAG GTCAACGACA AAGAGGTGTC GGACCGCATC 
AGCTCCCTGG GCAGCCAGGC CATGCAGATG GAGCGCAAAA AGTCCCAGCA CGGCGCGGGC 
TCGAGCGTGG GGGATGCATC CAGGCCCCCT TACCGGGGAC GCTCCTCGGA GAGCAGCTGC 
GGCGTCGACG GCGACTACGA GGACGCCGAG TTGAACCCCC GCTTCCTGAA GGACAACCTG 
ATCGACGCCA ATGGCGGTAG CAGGCCCCCT TGGCCGCCCC TGGAGTACCA GCCCTACCAG 
AGCATCTACG TCGGGGGCAT GATGGAAGGG GAGGGCAAGG GCCCGCTCCT GCGCAGCCAG 
AGCACCTCTG AGCAGGAGAA GCGCCTTACC TGGCCCCGCA GGTCCTACTC CCCCCGGAGT 
TTTGAGGATT GCGGAGGCGG CTATACCCCG GACTGCAGCT CCAATGAGAA CCTCACCTCC 
AGCGAGGAGG ACTTCTCCTC TGGCCAGTCC AGCCGCGTGT CCCCAAGCCC CACCACCTAC 
CGCATGTTCC GGGACAAAAG CCGCTCTCCC TCGCAGAACT CGCAACAGTC CTTCGACAGC 
AGCAGTCCCC CCACGCCGCA GTGCCATAAG CGGCACCGGC ACTGCCCGGT TGTCGTGTCC 
GAGGCCACCA TCGTGGGCGT CCGCAAGACC GGGCAGATCT GGCCCAACGA TGGCGAGGGC 
GCCTTCCATG GAGACGCAGA TGGCTCGTTC GGAACACCAC CTGGATACGG CTGCGCTGCA 
GACCGGGCAG AGGAGCAGCG CCGGCACCAA GATGGGCTGC CCTACATTGA TGACTCGCCC 
TCCTCATCGC CCCACCTCAG CAGCAAGGGC AGGGGCAGCC GGGATGCGCT GGTCTCGGGA 
GCCCTGGAGT CCACTAAAGC GAGTGAGCTG GACTTGGAAA AGGGCTTGGA GATGAGAAAA 
TGGGTCCTGT CGGGAATCCT GGCTAGCGAG GAGACTTACC TGAGCCACCT GGAGGCACTG 
CTGCTGCCCA TGAAGCCTTT GAAAGCCGCT GCCACCACCT CTCAGCCGGT GCTGACGAGT 
CAGCAGATCG AGACCATCTT CTTCAAAGTG CCTGAGCTCT ACGAGATCCA CAAGGAGTTC 
TATGATGGGC TCTTCCCCCG CGTGCAGCAG TGGAGCCACC AGCAGCGGGT GGGCGACCTC 
TTCCAGAAGC TGGCCAGCCA GCTGGGTGTG TACCGGGCCT TCGTGGACAA CTACGGAGTT 
GCCATGGAAA TGGCTGAGAA GTGCTGTCAG GCCAATGCTC AGTTTGCAGA AATCTCCGAG 
AACCTGAGAG CCAGAAGCAA CAAAGATGCC AAGGATCCAA CGACCAAGAA CTCTCTGGAA 
ACTCTGCTCT ACAAGCCTGT GGACCGTGTG ACGAGGAGCA CGCTGGTCCT CCATGACTTG 
CTGAAGCACA CTCCTGCCAG CCACCCTGAC CACCCCTTGC TGCAGGACGC CCTCCGCATC 
TCACAGAACT TCCTGTCCAG CATCAATGAG GAGATCACAC CCCGACGGCA GTCCATGACG 
GTGAAGAAGG GAGAGCACCG GCAGCTGCTG AAGGACAGCT TCATGGTGGA GCTGGTGGAG 
GGGGCCCGCA AGCTGCGCCA CGTCTTCCTG TTCACCGACC TGCTTCTCTG CACCAAGCTC 
AAGAAGCAGA GCGGAGGCAA AACGCAGCAG TATGACTGCA AATGGTACAT TCCGCTCACG 
GATCTCAGCT TCCAGATGGT GGATGAACTG GAGGCAGTGC CCAACATCCC CCTGGTGCCC 
GATGAGGAGC TGGACGCTTT GAAGATCAAG ATCTCCCAGA TCAAGAATGA CATCCAGAGA 
GAGAAGAGGG CGAACAAGGG CAGCAAGGCT ACGGAGAGGC TGAAGAAGAA GCTGTCGGAG 
CAGGAGTCAC TGCTGCTGCT TATGTCTCCC AGCATGGCCT TCAGGGTGCA CAGCCGCAAC 
GGCAAGAGTT ACACGTTCCT GATCTCCTCT GACTATGAGC GTGCAGAGTG GAGGGAGAAC 
ATCCGGGAGC AGCAGAAGAA GTGTTTCAGA AGCTTCTCCC TGACATCCGT GGAGCTGCAG 
ATGCTGACCA ACTCGTGTGT GAAACTCCAG ACTGTCCACA GCATTCCGCT GACCATCAAT 
AAGGAAGATG ATGAGTCTCC GGGGCTCTAT GGGTTTCTGA ATGTCATCGT CCACTCAGCC 
ACTGGATTTA AGCAGAGTTC AAATCTGTAC TGCACCCTGG AGGTGGATTC CTTTGGGTAT 
TTTGTGAATA AAGCAAAGAC GCGCGTCTAC AGGGACACAG CTGAGCCAAA CTGGAACGAG 
GAATTTGAGA TAGAGCTGGA GGGCTCCCAG ACCCTGAGGA TACTGTGCTA TGAAAAGTGT 
TACAACAAGA CGAAGATCCC CAAGGAGGAC GGCGAGAGCA CGGACAGACT CATGGGGAAG 
GGCCAGGTCC AGCTGGACCC GCAGGCCCTG CAGGACAGAG ACTGGCAGCG CACCGTCATC 
GCCATGAATG GGATCGAAGT AAAGCTCTCG GTCAAGTTCA ACAGCAGGGA GTTCAGCTTG 
AAGAGGATGC CGTCCCGAAA ACAGACAGGG GTCTTCGGAG TCAAGATTGC TGTGGTCACC 
AAGAGAGAGA GGTCCAAGGT GCCCTACATC GTGCGCCAGT GCGTGGAGGA GATCGAGCGC 
CGAGGCATGG AGGAGGTGGG CATCTACCGC GTGTCCGGTG TGGCCACGGA CATCCAGGCA 
CTGAAGGCAG CCTTCGACGT CAATAACAAG GACGTGTCGG TGATGATGAG CGAGATGGAC 
GTGAACGCCA TCGCAGGCAC GCTGAAGCTG TACTTCCGTG AGCTGCCCGA GCCCCTCTTC 
ACTGACGAGT TCTACCCCAA CTTCGCAGAG GGCATCGCTC TTTCAGACCC GGTTGCAAAG 
GAGAGCTGCA TGCTCAACCT GCTGCTGTCC CTGCCGGAGG CCAACCTGCT CACCTTCCTT 
TTCCTTCTGG ACCACCTGAA AAGGGTGGCA GAGAAGGAGG CAGTCAATAA GATGTCCCTG 
CACAACCTCG CCACGGTCTT TGGCCCCACG CTGCTCCGGC CCTCCGAGAA GGAGAGCAAG 
CTCCCTGCCA ACCCCAGCCA GCCTATCACC ATGACTGACA GCTGGTCCTT GGAGGTCATG 
TCCCAGGTCC AGGTGCTGCT GTACTTCCTG CAGCTGGAGG CCATCCCTGC CCCGGACAGC 
AAGAGACAGA GCATCCTGTT CTCCACCGAA GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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BCR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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