Gene Symbol | PAPPA2 |
Entrez Gene ID | 60676 |
Full Name | pappalysin 2 |
Synonyms | PAPP-A2,PAPP-E,PAPPE,PLAC3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]. |