Gene Symbol | GRK1 |
Entrez Gene ID | 6011 |
Full Name | G protein-coupled receptor kinase 1 |
Synonyms | GPRK1,RHOK,RK |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Oguchi disease-2, 613411 (3) |