RENBP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RENBP
Entrez Gene ID	5973
Full Name	renin binding protein
Synonyms	RBP,RNBP
General protein information	Preferred Names renin binding protein Names N-acylglucosamine 2-epimerase AGE GlcNAc 2-epimerase N-acetyl-D-glucosamine 2-epimerase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq28
Summary	The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008].
Disorder MIM:	312420

mRNA and Protein(s)

mRNA	Protein	Name
NM_002910.5	NP_002901.2	N-acylglucosamine 2-epimerase
XM_017029698.1	XP_016885187.1	N-acylglucosamine 2-epimerase isoform X1
NM_002910.6	NP_002901.2	N-acylglucosamine 2-epimerase

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	renbp	NP_001106581.1
Pan troglodytes (chimpanzee)	RENBP	XP_003317823.1
Homo sapiens (human)	RENBP	NP_002901.2
Canis lupus familiaris (dog)	RENBP	XP_855355.4
Mus musculus (house mouse)	Renbp	NP_075621.3
Bos taurus (cattle)	RENBP	NP_001039688.1
Rattus norvegicus (Norway rat)	Renbp	NP_112357.1
Danio rerio (zebrafish)	renbp	NP_001119915.1

Gene Ontology
Bibliography

Related articles in PubMed

Common variants on Xq28 conferring risk of schizophrenia in Han Chinese.
Wong EH, So HC, Li M, Wang Q, Butler AW, Paul B, Wu HM, Hui TC, Choi SC, So MT, Garcia-Barcelo MM, McAlonan GM, Chen EY, Cheung EF, Chan RC, Purcell SM, Cherny SS, Chen RR, Li T, Sham PC
Schizophrenia bulletin40(4)777-86(2014 Jul)

Association of renin binding protein (RnBP) gene polymorphisms with essential hypertension in the Hani minority of southwestern China.
Dong Y, Ding Y, Cun Y, Xiao C
Journal of genetics and genomics = Yi chuan xue bao40(8)433-6(2013 Aug)

Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid.
Bergfeld AK, Pearce OM, Diaz SL, Pham T, Varki A
The Journal of biological chemistry287(34)28865-81(2012 Aug)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.
Gu D, Kelly TN, Hixson JE, Chen J, Liu D, Chen JC, Rao DC, Mu J, Ma J, Jaquish CE, Rice TK, Gu C, Hamm LL, Whelton PK, He J
Journal of hypertension28(6)1210-20(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

rs2269372 in RENBP was associated with risk of schizophrenia in a Han Chinese population.
Title: Common variants on Xq28 conferring risk of schizophrenia in Han Chinese.

several SNPs and haplotypes of the RnBP gene are associated with either increased or decreased risk of developing essential hypertension.
Title: Association of renin binding protein (RnBP) gene polymorphisms with essential hypertension in the Hani minority of southwestern China.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following RENBP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RENBP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19506	NM_002910.6 Latest version!	Homo sapiens renin binding protein (RENBP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu99410	XM_017029698.1 Latest version!	Homo sapiens renin binding protein (RENBP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu19506	NM_002910.5	Homo sapiens renin binding protein (RENBP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RENBP ( NM_002910.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002901.2 Homo sapiens renin binding protein (RENBP), mRNA.

Price & Availability↑

CloneID	OHu19506
Clone ID Related Accession (Same CDS sequence)	NM_002910.5 , NM_002910.6
Accession Version	NM_002910.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	N-acylglucosamine 2-epimerase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U52112.2, AK298125.1, D10232.1 and BC015558.2. This sequence is a reference standard in the RefSeqGene project. On Nov 19, 2008 this sequence version replaced NM_002910.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no quality transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and PMID:1618798. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015558.2, SRR1163657.3013.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGAGCAAGG GTCTCCCAGC GCGACAGGAC ATGGAGAAAG AGCGAGAGAC TCTGCAGGCC 
TGGAAGGAGC GCGTGGGGCA GGAGCTGGAC CGCGTGGTGG CTTTCTGGAT GGAGCACTCC 
CACGACCAGG AGCACGGGGG CTTCTTCACG TGCCTTGGCC GCGAGGGGCG GGTGTATGAT 
GACCTCAAGT ATGTGTGGCT GCAGGGGAGG CAGGTATGGA TGTATTGTCG CCTGTACCGC 
ACTTTCGAGC GCTTCCGCCA TGCTCAGCTT CTGGACGCAG CAAAAGCAGG TGGTGAGTTC 
TTGCTGCGGT ATGCCCGGGT GGCACCTCCT GGCAAGAAGT GTGCCTTTGT GCTGACTCGG 
GACGGCCGCC CGGTCAAGGT GCAGCGAACC ATCTTCAGTG AGTGTTTCTA CACCATGGCC 
ATGAACGAGC TGTGGAGAGC CACAGGGGAA GTGCGGTACC AGACGGAAGC GGTGGAGATG 
ATGGATCAGA TCGTCCACTG GGTGCAGGAG GACGCGTCGG GACTGGGCCG GCCCCAGCTC 
CAGGGGGCCC CGGCTGCGGA GCCCATGGCG GTGCCCATGA TGCTACTGAA CCTGGTGGAG 
CAGCTCGGGG AGGCAGATGA GGAGCTGGCG GGCAAATACG CAGAGCTGGG GGACTGGTGC 
GCCCGGAGGA TTCTGCAGCA CGTGCAGAGG GATGGACAAG CTGTGCTGGA GAATGTGTCA 
GAGGGTGGCA AGGAACTTCC TGGCTGCCTG GGGAGACAGC AGAACCCAGG CCACACGCTG 
GAAGCCGGCT GGTTTCTGCT CCGTCATTGC ATTCGGAAAG GCGACCCCGA ACTTCGAGCC 
CACGTGATTG ACAAGTTCCT ATTGTTGCCC TTCCACTCCG GATGGGACCC TGACCACGGA 
GGCCTCTTTT ACTTCCAGGA TGCTGATAAC TTCTGCCCCA CCCAGCTGGA GTGGGCCATG 
AAGCTCTGGT GGCCACACAG TGAAGCCATG ATTGCCTTCC TCATGGGTTA CAGTGACAGT 
GGGGACCCTG TGCTGCTGCG CCTCTTCTAC CAAGTGGCTG AGTACACCTT CCGCCAGTTT 
CGCGATCCCG AGTACGGGGA ATGGTTTGGC TACCTGAGCC GAGAGGGCAA GGTGGCCCTC 
TCCATCAAGG GAGGTCCTTT CAAAGGCTGC TTCCACGTGC CGCGGTGCCT AGCCATGTGC 
GAGGAGATGC TGGGCGCCCT GCTGAGCCGC CCCGCCCCCG CCCCCTCCCC CGCCCCCACC 
CCCGCCTGCC GAGGCGCGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002901.2
CDS	171..1454
Translation	MSKGLPARQDMEKERETLQAWKERVGQELDRVVAFWMEHSHDQEHGGFFTCLGREGRVYDDLKYVWLQGRQVWMYCRLYRTFERFRHAQLLDAAKAGGEFLLRYARVAPPGKKCAFVLTRDGRPVKVQRTIFSECFYTMAMNELWRATGEVRYQTEAVEMMDQIVHWVQEDASGLGRPQLQGAPAAEPMAVPMMLLNLVEQLGEADEELAGKYAELGDWCARRILQHVQRDGQAVLENVSEGGKELPGCLGRQQNPGHTLEAGWFLLRHCIRKGDPELRAHVIDKFLLLPFHSGWDPDHGGLFYFQDADNFCPTQLEWAMKLWWPHSEAMIAFLMGYSDSGDPVLLRLFYQVAEYTFRQFRDPEYGEWFGYLSREGKVALSIKGGPFKGCFHVPRCLAMCEEMLGALLSRPAPAPSPAPTPACRGAE

Target ORF information:

RefSeq Version	NM_002910.5
Organism	Homo sapiens(human)
Definition	Homo sapiens renin binding protein (RENBP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002910.5

ORF Insert Sequence:

ATGAGCAAGG GTCTCCCAGC GCGACAGGAC ATGGAGAAAG AGCGAGAGAC TCTGCAGGCC 
TGGAAGGAGC GCGTGGGGCA GGAGCTGGAC CGCGTGGTGG CTTTCTGGAT GGAGCACTCC 
CACGACCAGG AGCACGGGGG CTTCTTCACG TGCCTTGGCC GCGAGGGGCG GGTGTATGAT 
GACCTCAAGT ATGTGTGGCT GCAGGGGAGG CAGGTATGGA TGTATTGTCG CCTGTACCGC 
ACTTTCGAGC GCTTCCGCCA TGCTCAGCTT CTGGACGCAG CAAAAGCAGG TGGTGAGTTC 
TTGCTGCGGT ATGCCCGGGT GGCACCTCCT GGCAAGAAGT GTGCCTTTGT GCTGACTCGG 
GACGGCCGCC CGGTCAAGGT GCAGCGAACC ATCTTCAGTG AGTGTTTCTA CACCATGGCC 
ATGAACGAGC TGTGGAGAGC CACAGGGGAA GTGCGGTACC AGACGGAAGC GGTGGAGATG 
ATGGATCAGA TCGTCCACTG GGTGCAGGAG GACGCGTCGG GACTGGGCCG GCCCCAGCTC 
CAGGGGGCCC CGGCTGCGGA GCCCATGGCG GTGCCCATGA TGCTACTGAA CCTGGTGGAG 
CAGCTCGGGG AGGCAGATGA GGAGCTGGCG GGCAAATACG CAGAGCTGGG GGACTGGTGC 
GCCCGGAGGA TTCTGCAGCA CGTGCAGAGG GATGGACAAG CTGTGCTGGA GAATGTGTCA 
GAGGGTGGCA AGGAACTTCC TGGCTGCCTG GGGAGACAGC AGAACCCAGG CCACACGCTG 
GAAGCCGGCT GGTTTCTGCT CCGTCATTGC ATTCGGAAAG GCGACCCCGA ACTTCGAGCC 
CACGTGATTG ACAAGTTCCT ATTGTTGCCC TTCCACTCCG GATGGGACCC TGACCACGGA 
GGCCTCTTTT ACTTCCAGGA TGCTGATAAC TTCTGCCCCA CCCAGCTGGA GTGGGCCATG 
AAGCTCTGGT GGCCACACAG TGAAGCCATG ATTGCCTTCC TCATGGGTTA CAGTGACAGT 
GGGGACCCTG TGCTGCTGCG CCTCTTCTAC CAAGTGGCTG AGTACACCTT CCGCCAGTTT 
CGCGATCCCG AGTACGGGGA ATGGTTTGGC TACCTGAGCC GAGAGGGCAA GGTGGCCCTC 
TCCATCAAGG GAGGTCCTTT CAAAGGCTGC TTCCACGTGC CGCGGTGCCT AGCCATGTGC 
GAGGAGATGC TGGGCGCCCT GCTGAGCCGC CCCGCCCCCG CCCCCTCCCC CGCCCCCACC 
CCCGCCTGCC GAGGCGCGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RENBP ( NM_002910.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_002901.2 Homo sapiens renin binding protein (RENBP), mRNA.

Price & Availability↑

CloneID	OHu19506
Clone ID Related Accession (Same CDS sequence)	NM_002910.5 , NM_002910.6
Accession Version	NM_002910.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	N-acylglucosamine 2-epimerase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK298125.1, D10232.1 and BC015558.2. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_002910.5. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no quality transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and PMID:1618798. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015558.2, SRR1163657.3013.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000393700.8/ ENSP00000377303.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCAAGG GTCTCCCAGC GCGACAGGAC ATGGAGAAAG AGCGAGAGAC TCTGCAGGCC 
TGGAAGGAGC GCGTGGGGCA GGAGCTGGAC CGCGTGGTGG CTTTCTGGAT GGAGCACTCC 
CACGACCAGG AGCACGGGGG CTTCTTCACG TGCCTTGGCC GCGAGGGGCG GGTGTATGAT 
GACCTCAAGT ATGTGTGGCT GCAGGGGAGG CAGGTATGGA TGTATTGTCG CCTGTACCGC 
ACTTTCGAGC GCTTCCGCCA TGCTCAGCTT CTGGACGCAG CAAAAGCAGG TGGTGAGTTC 
TTGCTGCGGT ATGCCCGGGT GGCACCTCCT GGCAAGAAGT GTGCCTTTGT GCTGACTCGG 
GACGGCCGCC CGGTCAAGGT GCAGCGAACC ATCTTCAGTG AGTGTTTCTA CACCATGGCC 
ATGAACGAGC TGTGGAGAGC CACAGGGGAA GTGCGGTACC AGACGGAAGC GGTGGAGATG 
ATGGATCAGA TCGTCCACTG GGTGCAGGAG GACGCGTCGG GACTGGGCCG GCCCCAGCTC 
CAGGGGGCCC CGGCTGCGGA GCCCATGGCG GTGCCCATGA TGCTACTGAA CCTGGTGGAG 
CAGCTCGGGG AGGCAGATGA GGAGCTGGCG GGCAAATACG CAGAGCTGGG GGACTGGTGC 
GCCCGGAGGA TTCTGCAGCA CGTGCAGAGG GATGGACAAG CTGTGCTGGA GAATGTGTCA 
GAGGGTGGCA AGGAACTTCC TGGCTGCCTG GGGAGACAGC AGAACCCAGG CCACACGCTG 
GAAGCCGGCT GGTTTCTGCT CCGTCATTGC ATTCGGAAAG GCGACCCCGA ACTTCGAGCC 
CACGTGATTG ACAAGTTCCT ATTGTTGCCC TTCCACTCCG GATGGGACCC TGACCACGGA 
GGCCTCTTTT ACTTCCAGGA TGCTGATAAC TTCTGCCCCA CCCAGCTGGA GTGGGCCATG 
AAGCTCTGGT GGCCACACAG TGAAGCCATG ATTGCCTTCC TCATGGGTTA CAGTGACAGT 
GGGGACCCTG TGCTGCTGCG CCTCTTCTAC CAAGTGGCTG AGTACACCTT CCGCCAGTTT 
CGCGATCCCG AGTACGGGGA ATGGTTTGGC TACCTGAGCC GAGAGGGCAA GGTGGCCCTC 
TCCATCAAGG GAGGTCCTTT CAAAGGCTGC TTCCACGTGC CGCGGTGCCT AGCCATGTGC 
GAGGAGATGC TGGGCGCCCT GCTGAGCCGC CCCGCCCCCG CCCCCTCCCC CGCCCCCACC 
CCCGCCTGCC GAGGCGCGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002901.2
CDS	34..1317
Translation	MSKGLPARQDMEKERETLQAWKERVGQELDRVVAFWMEHSHDQEHGGFFTCLGREGRVYDDLKYVWLQGRQVWMYCRLYRTFERFRHAQLLDAAKAGGEFLLRYARVAPPGKKCAFVLTRDGRPVKVQRTIFSECFYTMAMNELWRATGEVRYQTEAVEMMDQIVHWVQEDASGLGRPQLQGAPAAEPMAVPMMLLNLVEQLGEADEELAGKYAELGDWCARRILQHVQRDGQAVLENVSEGGKELPGCLGRQQNPGHTLEAGWFLLRHCIRKGDPELRAHVIDKFLLLPFHSGWDPDHGGLFYFQDADNFCPTQLEWAMKLWWPHSEAMIAFLMGYSDSGDPVLLRLFYQVAEYTFRQFRDPEYGEWFGYLSREGKVALSIKGGPFKGCFHVPRCLAMCEEMLGALLSRPAPAPSPAPTPACRGAE

Target ORF information:

RefSeq Version	NM_002910.6
Organism	Homo sapiens(human)
Definition	Homo sapiens renin binding protein (RENBP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002910.6

ORF Insert Sequence:

ATGAGCAAGG GTCTCCCAGC GCGACAGGAC ATGGAGAAAG AGCGAGAGAC TCTGCAGGCC 
TGGAAGGAGC GCGTGGGGCA GGAGCTGGAC CGCGTGGTGG CTTTCTGGAT GGAGCACTCC 
CACGACCAGG AGCACGGGGG CTTCTTCACG TGCCTTGGCC GCGAGGGGCG GGTGTATGAT 
GACCTCAAGT ATGTGTGGCT GCAGGGGAGG CAGGTATGGA TGTATTGTCG CCTGTACCGC 
ACTTTCGAGC GCTTCCGCCA TGCTCAGCTT CTGGACGCAG CAAAAGCAGG TGGTGAGTTC 
TTGCTGCGGT ATGCCCGGGT GGCACCTCCT GGCAAGAAGT GTGCCTTTGT GCTGACTCGG 
GACGGCCGCC CGGTCAAGGT GCAGCGAACC ATCTTCAGTG AGTGTTTCTA CACCATGGCC 
ATGAACGAGC TGTGGAGAGC CACAGGGGAA GTGCGGTACC AGACGGAAGC GGTGGAGATG 
ATGGATCAGA TCGTCCACTG GGTGCAGGAG GACGCGTCGG GACTGGGCCG GCCCCAGCTC 
CAGGGGGCCC CGGCTGCGGA GCCCATGGCG GTGCCCATGA TGCTACTGAA CCTGGTGGAG 
CAGCTCGGGG AGGCAGATGA GGAGCTGGCG GGCAAATACG CAGAGCTGGG GGACTGGTGC 
GCCCGGAGGA TTCTGCAGCA CGTGCAGAGG GATGGACAAG CTGTGCTGGA GAATGTGTCA 
GAGGGTGGCA AGGAACTTCC TGGCTGCCTG GGGAGACAGC AGAACCCAGG CCACACGCTG 
GAAGCCGGCT GGTTTCTGCT CCGTCATTGC ATTCGGAAAG GCGACCCCGA ACTTCGAGCC 
CACGTGATTG ACAAGTTCCT ATTGTTGCCC TTCCACTCCG GATGGGACCC TGACCACGGA 
GGCCTCTTTT ACTTCCAGGA TGCTGATAAC TTCTGCCCCA CCCAGCTGGA GTGGGCCATG 
AAGCTCTGGT GGCCACACAG TGAAGCCATG ATTGCCTTCC TCATGGGTTA CAGTGACAGT 
GGGGACCCTG TGCTGCTGCG CCTCTTCTAC CAAGTGGCTG AGTACACCTT CCGCCAGTTT 
CGCGATCCCG AGTACGGGGA ATGGTTTGGC TACCTGAGCC GAGAGGGCAA GGTGGCCCTC 
TCCATCAAGG GAGGTCCTTT CAAAGGCTGC TTCCACGTGC CGCGGTGCCT AGCCATGTGC 
GAGGAGATGC TGGGCGCCCT GCTGAGCCGC CCCGCCCCCG CCCCCTCCCC CGCCCCCACC 
CCCGCCTGCC GAGGCGCGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RENBP ( XM_017029698.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885187.1 Homo sapiens renin binding protein (RENBP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu99410
Clone ID Related Accession (Same CDS sequence)	XM_017029698.1
Accession Version	XM_017029698.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	N-acylglucosamine 2-epimerase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAAG AGCGAGAGAC TCTGCAGGCC TGGAAGGAGC GCGTGGGGCA GGAGCTGGAC 
CGCGTGGTGG CTTTCTGGAT GGAGCACTCC CACGACCAGG AGCACGGGGG CTTCTTCACG 
TGCCTTGGCC GCGAGGGGCG GGTGTATGAT GACCTCAAGT ATGTGTGGCT GCAGGGGAGG 
CAGGTATGGA TGTATTGTCG CCTGTACCGC ACTTTCGAGC GCTTCCGCCA TGCTCAGCTT 
CTGGACGCAG CAAAAGCAGG TGGTGAGTTC TTGCTGCGGT ATGCCCGGGT GGCACCTCCT 
GGCAAGAAGT GTGCCTTTGT GCTGACTCGG GACGGCCGCC CGGTCAAGGT GCAGCGAACC 
ATCTTCAGTG AGTGTTTCTA CACCATGGCC ATGAACGAGC TGTGGAGAGC CACAGGGGAA 
GTGCGGTACC AGACGGAAGC GGTGGAGATG ATGGATCAGA TCGTCCACTG GGTGCAGGAG 
GACGCGTCGG GACTGGGCCG GCCCCAGCTC CAGGGGGCCC CGGCTGCGGA GCCCATGGCG 
GTGCCCATGA TGCTACTGAA CCTGGTGGAG CAGCTCGGGG AGGCAGATGA GGAGCTGGCG 
GGCAAATACG CAGAGCTGGG GGACTGGTGC GCCCGGAGGA TTCTGCAGCA CGTGCAGAGG 
GATGGACAAG CTGTGCTGGA GAATGTGTCA GAGGGTGGCA AGGAACTTCC TGGCTGCCTG 
GGGAGACAGC AGAACCCAGG CCACACGCTG GAAGCCGGCT GGTTTCTGCT CCGTCATTGC 
ATTCGGAAAG GCGACCCCGA ACTTCGAGCC CACGTGATTG ACAAGTTCCT ATTGTTGCCC 
TTCCACTCCG GATGGGACCC TGACCACGGA GGCCTCTTTT ACTTCCAGGA TGCTGATAAC 
TTCTGCCCCA CCCAGCTGGA GTGGGCCATG AAGCTCTGGT GGCCACACAG TGAAGCCATG 
ATTGCCTTCC TCATGGGTTA CAGTGACAGT GGGGACCCTG TGCTGCTGCG CCTCTTCTAC 
CAAGTGGCTG AGTACACCTT CCGCCAGTTT CGCGATCCCG AGTACGGGGA ATGGTTTGGC 
TACCTGAGCC GAGAGGGCAA GGTGGCCCTC TCCATCAAGG GAGGTCCTTT CAAAGGCTGC 
TTCCACGTGC CGCGGTGCCT AGCCATGTGC GAGGAGATGC TGGGCGCCCT GCTGAGCCGC 
CCCGCCCCCG CCCCCTCCCC CGCCCCCACC CCCGCCTGCC GAGGCGCGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885187.1
CDS	96..1349
Translation	MEKERETLQAWKERVGQELDRVVAFWMEHSHDQEHGGFFTCLGREGRVYDDLKYVWLQGRQVWMYCRLYRTFERFRHAQLLDAAKAGGEFLLRYARVAPPGKKCAFVLTRDGRPVKVQRTIFSECFYTMAMNELWRATGEVRYQTEAVEMMDQIVHWVQEDASGLGRPQLQGAPAAEPMAVPMMLLNLVEQLGEADEELAGKYAELGDWCARRILQHVQRDGQAVLENVSEGGKELPGCLGRQQNPGHTLEAGWFLLRHCIRKGDPELRAHVIDKFLLLPFHSGWDPDHGGLFYFQDADNFCPTQLEWAMKLWWPHSEAMIAFLMGYSDSGDPVLLRLFYQVAEYTFRQFRDPEYGEWFGYLSREGKVALSIKGGPFKGCFHVPRCLAMCEEMLGALLSRPAPAPSPAPTPACRGAE

Target ORF information:

RefSeq Version	XM_017029698.1
Organism	Homo sapiens(human)
Definition	Homo sapiens renin binding protein (RENBP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029698.1

ORF Insert Sequence:

ATGGAGAAAG AGCGAGAGAC TCTGCAGGCC TGGAAGGAGC GCGTGGGGCA GGAGCTGGAC 
CGCGTGGTGG CTTTCTGGAT GGAGCACTCC CACGACCAGG AGCACGGGGG CTTCTTCACG 
TGCCTTGGCC GCGAGGGGCG GGTGTATGAT GACCTCAAGT ATGTGTGGCT GCAGGGGAGG 
CAGGTATGGA TGTATTGTCG CCTGTACCGC ACTTTCGAGC GCTTCCGCCA TGCTCAGCTT 
CTGGACGCAG CAAAAGCAGG TGGTGAGTTC TTGCTGCGGT ATGCCCGGGT GGCACCTCCT 
GGCAAGAAGT GTGCCTTTGT GCTGACTCGG GACGGCCGCC CGGTCAAGGT GCAGCGAACC 
ATCTTCAGTG AGTGTTTCTA CACCATGGCC ATGAACGAGC TGTGGAGAGC CACAGGGGAA 
GTGCGGTACC AGACGGAAGC GGTGGAGATG ATGGATCAGA TCGTCCACTG GGTGCAGGAG 
GACGCGTCGG GACTGGGCCG GCCCCAGCTC CAGGGGGCCC CGGCTGCGGA GCCCATGGCG 
GTGCCCATGA TGCTACTGAA CCTGGTGGAG CAGCTCGGGG AGGCAGATGA GGAGCTGGCG 
GGCAAATACG CAGAGCTGGG GGACTGGTGC GCCCGGAGGA TTCTGCAGCA CGTGCAGAGG 
GATGGACAAG CTGTGCTGGA GAATGTGTCA GAGGGTGGCA AGGAACTTCC TGGCTGCCTG 
GGGAGACAGC AGAACCCAGG CCACACGCTG GAAGCCGGCT GGTTTCTGCT CCGTCATTGC 
ATTCGGAAAG GCGACCCCGA ACTTCGAGCC CACGTGATTG ACAAGTTCCT ATTGTTGCCC 
TTCCACTCCG GATGGGACCC TGACCACGGA GGCCTCTTTT ACTTCCAGGA TGCTGATAAC 
TTCTGCCCCA CCCAGCTGGA GTGGGCCATG AAGCTCTGGT GGCCACACAG TGAAGCCATG 
ATTGCCTTCC TCATGGGTTA CAGTGACAGT GGGGACCCTG TGCTGCTGCG CCTCTTCTAC 
CAAGTGGCTG AGTACACCTT CCGCCAGTTT CGCGATCCCG AGTACGGGGA ATGGTTTGGC 
TACCTGAGCC GAGAGGGCAA GGTGGCCCTC TCCATCAAGG GAGGTCCTTT CAAAGGCTGC 
TTCCACGTGC CGCGGTGCCT AGCCATGTGC GAGGAGATGC TGGGCGCCCT GCTGAGCCGC 
CCCGCCCCCG CCCCCTCCCC CGCCCCCACC CCCGCCTGCC GAGGCGCGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common variants on Xq28 conferring risk of schizophrenia in Han Chinese.
Schizophrenia bulletin40(4)777-86(2014 Jul)
Wong EH,So HC,Li M,Wang Q,Butler AW,Paul B,Wu HM,Hui TC,Choi SC,So MT,Garcia-Barcelo MM,McAlonan GM,Chen EY,Cheung EF,Chan RC,Purcell SM,Cherny SS,Chen RR,Li T,Sham PC

Association of renin binding protein (RnBP) gene polymorphisms with essential hypertension in the Hani minority of southwestern China.
Journal of genetics and genomics = Yi chuan xue bao40(8)433-6(2013 Aug)
Dong Y,Ding Y,Cun Y,Xiao C

Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid.
The Journal of biological chemistry287(34)28865-81(2012 Aug)
Bergfeld AK,Pearce OM,Diaz SL,Pham T,Varki A

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Diabetes care33(10)2250-3(2010 Oct)
Bailey SD,Xie C,Do R,Montpetit A,Diaz R,Mohan V,Keavney B,Yusuf S,Gerstein HC,Engert JC,Anand S,

Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.
Journal of hypertension28(6)1210-20(2010 Jun)
Gu D,Kelly TN,Hixson JE,Chen J,Liu D,Chen JC,Rao DC,Mu J,Ma J,Jaquish CE,Rice TK,Gu C,Hamm LL,Whelton PK,He J

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RENBP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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