RDX cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RDX
Entrez Gene ID	5962
Full Name	radixin
Synonyms	DFNB24
General protein information	Preferred Names radixin Names radixin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q22.3
Summary	Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
Disorder MIM:	179410
Disorder Html:	Deafness, autosomal recessive 24, 611022 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002906.3	NP_002897.1	radixin isoform 2
NM_001260496.1	NP_001247425.1	radixin isoform 5
NM_001260492.1	NP_001247421.1	radixin isoform 1
NM_001260495.1	NP_001247424.1	radixin isoform 4
NM_001260493.1	NP_001247422.1	radixin isoform 1
NM_001260494.1	NP_001247423.1	radixin isoform 3
NM_002906.4	NP_002897.1	radixin isoform 2
NM_001260492.2	NP_001247421.1	radixin isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RDX	XP_536581.3
Homo sapiens (human)	RDX	NP_001247422.1
Pan troglodytes (chimpanzee)	RDX	XP_522176.4
	RDX	XP_001104955.1
Mus musculus (house mouse)	Rdx	NP_001098086.1
Rattus norvegicus (Norway rat)	Rdx	NP_001005889.2
Bos taurus (cattle)	RDX	NP_001069217.1
Danio rerio (zebrafish)	msnb	NP_001243180.1
Gallus gallus (chicken)	RDX	NP_990082.1
Danio rerio (zebrafish)	msna	NP_001004296.1

Gene Ontology
Bibliography

Related articles in PubMed

Dynamics and function of ERM proteins during cytokinesis in human cells.
Hiruma S, Kamasaki T, Otomo K, Nemoto T, Uehara R
FEBS letters591(20)3296-3309(2017 Oct)

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.
Riecken LB, Zoch A, Wiehl U, Reichert S, Scholl I, Cui Y, Ziemer M, Anderegg U, Hagel C, Morrison H
Oncotarget7(48)78242-78254(2016 Nov)

Knockdown of Radixin Suppresses Gastric Cancer Metastasis In Vitro by Up-Regulation of E-Cadherin via NF-?B/Snail Pathway.
Zhu YW, Yan JK, Li JJ, Ou YM, Yang Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology39(6)2509-2521(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results reveal a supportive role of ERMs in cortical activities during cytokinesis, and also provide insight into the selective mechanism that preferentially associates cytokinesis-relevant proteins with the division site.
Title: Dynamics and function of ERM proteins during cytokinesis in human cells.

These studies identify Akt2 as a critical kinase that regulates radixin phosphorylation and leads to Mrp-2 translocation and function.
Title: Akt2-Dependent Phosphorylation of Radixin in Regulation of Mrp-2 Trafficking in WIF-B Cells.

Radixin knockdown suppresses the metastasis of SGC-7901 cells in vitro by up-regulation of E-cadherin. The NF-kappaB/snail pathway contributes to the regulation of E-cadherin in response to depletion of radixin.
Title: Knockdown of Radixin Suppresses Gastric Cancer Metastasis In Vitro by Up-Regulation of E-Cadherin via NF-?B/Snail Pathway.

Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.
Title: Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.

Phospho-Ezrin/Radixin/Moesin (ERM) inhibit cell adhesion, and therefore, dephosphorylation of ERM proteins is essential for cell adhesion.Phospho-ERM induce formation and/or maintenance of spherical cell shape.
Title: Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.

The following RDX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RDX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12465	NM_001260493.1 Latest version!	Homo sapiens radixin (RDX), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu10254	NM_001260495.1 Latest version!	Homo sapiens radixin (RDX), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu11531	NM_001260496.1 Latest version!	Homo sapiens radixin (RDX), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu12421	NM_001260494.1 Latest version!	Homo sapiens radixin (RDX), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu12465	NM_001260492.2 Latest version!	Homo sapiens radixin (RDX), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu26036	NM_002906.4 Latest version!	Homo sapiens radixin (RDX), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu26036	NM_002906.3	Homo sapiens radixin (RDX), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu12465	NM_001260492.1	Homo sapiens radixin (RDX), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RDX ( NM_001260493.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001247422.1 Homo sapiens radixin (RDX), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12465
Clone ID Related Accession (Same CDS sequence)	NM_001260492.1 , NM_001260493.1 , NM_001260492.2
Accession Version	NM_001260493.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	radixin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ916742.1. Transcript Variant: This variant (2) differs in the 3' UTR exon, compared to variant 1. Both variants 1 and 2 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ916742.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GGGGACCCAA ACTGTATGCA TTGTTCCAGA TGCGCTCTTG CCAAAGCAGC 
ATAAAGCAAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247422.1
CDS	311..2125
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSSIKQM

Target ORF information:

RefSeq Version	NM_001260493.1
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260493.1

ORF Insert Sequence:

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GGGGACCCAA ACTGTATGCA TTGTTCCAGA TGCGCTCTTG CCAAAGCAGC 
ATAAAGCAAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_001260495.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001247424.1 Homo sapiens radixin (RDX), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu10254
Clone ID Related Accession (Same CDS sequence)	NM_001260495.1
Accession Version	NM_001260495.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Homo sapiens(human)
Product	radixin isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ916740.1 and AP000901.5. Transcript Variant: This variant (5) lacks multiple exons in the coding region, compared to variant 1. The resulting isoform (4) lacks two internal segments, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ916740.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2144333, SAMEA2148093 [ECO:0000350] ##Evidence-Data-END##

ATGGAACGTC TAAAACAAAT TGAAGAGCAG ACAATTAAAG CTCAGAAAGA ACTAGAAGAA 
CAGACTCGAA AAGCTCTAGA ACTGGATCAA GAACGAAAAC GAGCAAAAGA AGAAGCAGAA 
CGACTTGAAA AGGAGCGTCG AGCTGCTGAA GAGGCAAAGT CTGCCATAGC AAAACAAGCT 
GCCGACCAGA TGAAGAATCA GGAGCAGCTA GCAGCAGAAC TTGCTGAATT CACTGCCAAG 
ATTGCACTTC TAGAGGAAGC CAAGAAGAAA AAGGAAGAGG AAGCTACTGA GTGGCAACAC 
AAAGCTTTTG CAGCCCAGGA AGACTTGGAA AAGACCAAAG AAGAGTTAAA AACTGTGATG 
TCTGCCCCCC CTCCACCTCC ACCACCACCA GTCATTCCTC CAACAGAAAA CGAACATGAT 
GAACACGATG AGAATAATGC TGAAGCTAGT GCTGAATTAT CAAATGAAGG GGTAATGAAC 
CATAGAAGCG AGGAAGAACG TGTAACCGAA ACACAGAAAA ATGAGCGTGT TAAGAAGCAA 
CTTCAGGCAT TAAGTTCAGA ATTAGCCCAA GCCAGAGATG AAACCAAGAA AACACAAAAT 
GATGTTCTTC ATGCTGAGAA TGTTAAAGCA GGCCGTGATA AGTACAAGAC TCTGCGACAG 
ATTCGACAAG GCAATACAAA GCAGCGTATC GATGAGTTTG AAGCAATGTG GGGACCCAAA 
CTGTATGCAT TGTTCCAGAT GCGCTCTTGC CAAAGCAGCA TAAAGCAAAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247424.1
CDS	405..1178
Translation	MERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSSIKQM

Target ORF information:

RefSeq Version	NM_001260495.1
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260495.1

ORF Insert Sequence:

ATGGAACGTC TAAAACAAAT TGAAGAGCAG ACAATTAAAG CTCAGAAAGA ACTAGAAGAA 
CAGACTCGAA AAGCTCTAGA ACTGGATCAA GAACGAAAAC GAGCAAAAGA AGAAGCAGAA 
CGACTTGAAA AGGAGCGTCG AGCTGCTGAA GAGGCAAAGT CTGCCATAGC AAAACAAGCT 
GCCGACCAGA TGAAGAATCA GGAGCAGCTA GCAGCAGAAC TTGCTGAATT CACTGCCAAG 
ATTGCACTTC TAGAGGAAGC CAAGAAGAAA AAGGAAGAGG AAGCTACTGA GTGGCAACAC 
AAAGCTTTTG CAGCCCAGGA AGACTTGGAA AAGACCAAAG AAGAGTTAAA AACTGTGATG 
TCTGCCCCCC CTCCACCTCC ACCACCACCA GTCATTCCTC CAACAGAAAA CGAACATGAT 
GAACACGATG AGAATAATGC TGAAGCTAGT GCTGAATTAT CAAATGAAGG GGTAATGAAC 
CATAGAAGCG AGGAAGAACG TGTAACCGAA ACACAGAAAA ATGAGCGTGT TAAGAAGCAA 
CTTCAGGCAT TAAGTTCAGA ATTAGCCCAA GCCAGAGATG AAACCAAGAA AACACAAAAT 
GATGTTCTTC ATGCTGAGAA TGTTAAAGCA GGCCGTGATA AGTACAAGAC TCTGCGACAG 
ATTCGACAAG GCAATACAAA GCAGCGTATC GATGAGTTTG AAGCAATGTG GGGACCCAAA 
CTGTATGCAT TGTTCCAGAT GCGCTCTTGC CAAAGCAGCA TAAAGCAAAT GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_001260496.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001247425.1 Homo sapiens radixin (RDX), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu11531
Clone ID Related Accession (Same CDS sequence)	NM_001260496.1
Accession Version	NM_001260496.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Homo sapiens(human)
Product	radixin isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ916739.1 and AP000901.5. Transcript Variant: This variant (6) lacks multiple exons in the coding region, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ916739.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END##

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTAA CACAGCAGGA TGTTAAAAAA 
GAGAATCCTT TACAGTTCAA GTTTAGAGCT AAATTCTTTC CTGAAGATGT TTCTGAGGAA 
TTAATTCAAG AAATAACCCA GAGACTCTTC TTCTTGCAAG TTAAAGAAGC CATCTTAAAT 
GATGAGATAT ATTGCCCGCC AGAAACTGCA GTTCTTTTGG CTTCCTATGC TGTCCAAGCC 
AAGTATGGAG ATTACAATAA AGAGATTCAT AAGCCAGGCT ACCTGGCTAA TGATAGACTC 
CTACCCCAGC GTGTATTGGA ACAACACAAA CTAACAAAAG AACAAGATGA AACCAAGAAA 
ACACAAAATG ATGTTCTTCA TGCTGAGAAT GTTAAAGCAG GCCGTGATAA GTACAAGACT 
CTGCGACAGA TTCGACAAGG CAATACAAAG CAGCGTATCG ATGAGTTTGA AGCAATGTGG 
GGACCCAAAC TGTATGCATT GTTCCAGATG CGCTCTTGCC AAAGCAGCAT AAAGCAAATG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247425.1
CDS	311..913
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSSIKQM

Target ORF information:

RefSeq Version	NM_001260496.1
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260496.1

ORF Insert Sequence:

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTAA CACAGCAGGA TGTTAAAAAA 
GAGAATCCTT TACAGTTCAA GTTTAGAGCT AAATTCTTTC CTGAAGATGT TTCTGAGGAA 
TTAATTCAAG AAATAACCCA GAGACTCTTC TTCTTGCAAG TTAAAGAAGC CATCTTAAAT 
GATGAGATAT ATTGCCCGCC AGAAACTGCA GTTCTTTTGG CTTCCTATGC TGTCCAAGCC 
AAGTATGGAG ATTACAATAA AGAGATTCAT AAGCCAGGCT ACCTGGCTAA TGATAGACTC 
CTACCCCAGC GTGTATTGGA ACAACACAAA CTAACAAAAG AACAAGATGA AACCAAGAAA 
ACACAAAATG ATGTTCTTCA TGCTGAGAAT GTTAAAGCAG GCCGTGATAA GTACAAGACT 
CTGCGACAGA TTCGACAAGG CAATACAAAG CAGCGTATCG ATGAGTTTGA AGCAATGTGG 
GGACCCAAAC TGTATGCATT GTTCCAGATG CGCTCTTGCC AAAGCAGCAT AAAGCAAATG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_001260494.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001247423.1 Homo sapiens radixin (RDX), transcript variant 4, mRNA.

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CloneID	OHu12421
Clone ID Related Accession (Same CDS sequence)	NM_001260494.1
Accession Version	NM_001260494.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Homo sapiens(human)
Product	radixin isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ916738.1, AK316061.1, BC047109.1, AP000901.5 and N92548.1. Transcript Variant: This variant (4) lacks two internal coding exons and differs in the 3' region, compared to variant 1. The resulting isoform (3) lacks an internal segment and has a shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK316061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END##

ATGCTGAGCT GGAATTTGCC ATTCAGCCCA ATACAACTGG CAAACAACTT TTTGACCAGT 
GTATTGGAAC AACACAAACT AACAAAAGAA CAGTGGGAAG AAAGAATACA GAACTGGCAT 
GAAGAACATA GAGGAATGTT AAGGGAGGAT TCTATGATGG AATACCTGAA GATTGCACAA 
GATCTAGAAA TGTATGGAGT CAACTATTTT GAAATAAAAA ATAAAAAAGG AACTGAATTG 
TGGCTAGGTG TTGATGCTTT GGGTCTGAAT ATTTATGAGC ATGACGACAA GTTAACACCT 
AAAATTGGTT TTCCCTGGAG TGAAATCAGA AATATTTCAT TTAATGACAA AAAATTTGTT 
ATAAAGCCAA TCGACAAAAA GGCACCTGAT TTTGTGTTTT ATGCACCTCG TCTGAGAATC 
AATAAGCGGA TTTTGGCCTT ATGTATGGGA AACCATGAAC TATACATGCG AAGAAGGAAG 
CCTGATACTA TTGAAGTACA ACAGATGAAG GCTCAGGCTA GGGAGGAGAA ACATCAGAAG 
CAGTTGGAAA GGGCACAATT AGAGAATGAA AAGAAGAAAA GAGAAATAGC AGAAAAGGAA 
AAGGAAAGAA TAGAACGTGA AAAGGAAGAG CTAATGGAAC GTCTAAAACA AATTGAAGAG 
CAGACAATTA AAGCTCAGAA AGAACTAGAA GAACAGACTC GAAAAGCTCT AGAACTGGAT 
CAAGAACGAA AACGAGCAAA AGAAGAAGCA GAACGACTTG AAAAGGAGCG TCGAGCTGCT 
GAAGAGGCAA AGTCTGCCAT AGCAAAACAA GCTGCCGACC AGATGAAGAA TCAGGAGCAG 
CTAGCAGCAG AACTTGCTGA ATTCACTGCC AAGATTGCAC TTCTAGAGGA AGCCAAGAAG 
AAAAAGGAAG AGGAAGCTAC TGAGTGGCAA CACAAAGCTT TTGCAGCCCA GGAAGACTTG 
GAAAAGACCA AAGAAGAGTT AAAAACTGTG ATGTCTGCCC CCCCTCCACC TCCACCACCA 
CCAGTCATTC CTCCAACAGA AAACGAACAT GATGAACACG ATGAGAATAA TGCTGAAGCT 
AGTGCTGAAT TATCAAATGA AGGGGTAATG AACCATAGAA GCGAGGAAGA ACGTGTAACC 
GAAACACAGA AAAATGAGCG TGTTAAGAAG CAACTTCAGG CATTAAGTTC AGAATTAGCC 
CAAGCCAGAG ATGAAACCAA GAAAACACAA AATGATGTTC TTCATGCTGA GAATGTTAAA 
GCAGGCCGTG ATAAGTACAA GACTCTGCGA CAGATTCGAC AAGGCAATAC AAAGCAGCGT 
ATCGATGAGT TTGAAGCAAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247423.1
CDS	348..1691
Translation	MLSWNLPFSPIQLANNFLTSVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM

Target ORF information:

RefSeq Version	NM_001260494.1
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260494.1

ORF Insert Sequence:

ATGCTGAGCT GGAATTTGCC ATTCAGCCCA ATACAACTGG CAAACAACTT TTTGACCAGT 
GTATTGGAAC AACACAAACT AACAAAAGAA CAGTGGGAAG AAAGAATACA GAACTGGCAT 
GAAGAACATA GAGGAATGTT AAGGGAGGAT TCTATGATGG AATACCTGAA GATTGCACAA 
GATCTAGAAA TGTATGGAGT CAACTATTTT GAAATAAAAA ATAAAAAAGG AACTGAATTG 
TGGCTAGGTG TTGATGCTTT GGGTCTGAAT ATTTATGAGC ATGACGACAA GTTAACACCT 
AAAATTGGTT TTCCCTGGAG TGAAATCAGA AATATTTCAT TTAATGACAA AAAATTTGTT 
ATAAAGCCAA TCGACAAAAA GGCACCTGAT TTTGTGTTTT ATGCACCTCG TCTGAGAATC 
AATAAGCGGA TTTTGGCCTT ATGTATGGGA AACCATGAAC TATACATGCG AAGAAGGAAG 
CCTGATACTA TTGAAGTACA ACAGATGAAG GCTCAGGCTA GGGAGGAGAA ACATCAGAAG 
CAGTTGGAAA GGGCACAATT AGAGAATGAA AAGAAGAAAA GAGAAATAGC AGAAAAGGAA 
AAGGAAAGAA TAGAACGTGA AAAGGAAGAG CTAATGGAAC GTCTAAAACA AATTGAAGAG 
CAGACAATTA AAGCTCAGAA AGAACTAGAA GAACAGACTC GAAAAGCTCT AGAACTGGAT 
CAAGAACGAA AACGAGCAAA AGAAGAAGCA GAACGACTTG AAAAGGAGCG TCGAGCTGCT 
GAAGAGGCAA AGTCTGCCAT AGCAAAACAA GCTGCCGACC AGATGAAGAA TCAGGAGCAG 
CTAGCAGCAG AACTTGCTGA ATTCACTGCC AAGATTGCAC TTCTAGAGGA AGCCAAGAAG 
AAAAAGGAAG AGGAAGCTAC TGAGTGGCAA CACAAAGCTT TTGCAGCCCA GGAAGACTTG 
GAAAAGACCA AAGAAGAGTT AAAAACTGTG ATGTCTGCCC CCCCTCCACC TCCACCACCA 
CCAGTCATTC CTCCAACAGA AAACGAACAT GATGAACACG ATGAGAATAA TGCTGAAGCT 
AGTGCTGAAT TATCAAATGA AGGGGTAATG AACCATAGAA GCGAGGAAGA ACGTGTAACC 
GAAACACAGA AAAATGAGCG TGTTAAGAAG CAACTTCAGG CATTAAGTTC AGAATTAGCC 
CAAGCCAGAG ATGAAACCAA GAAAACACAA AATGATGTTC TTCATGCTGA GAATGTTAAA 
GCAGGCCGTG ATAAGTACAA GACTCTGCGA CAGATTCGAC AAGGCAATAC AAAGCAGCGT 
ATCGATGAGT TTGAAGCAAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_001260492.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001247421.1 Homo sapiens radixin (RDX), transcript variant 1, mRNA.

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CloneID	OHu12465
Clone ID Related Accession (Same CDS sequence)	NM_001260492.1 , NM_001260493.1 , NM_001260492.2
Accession Version	NM_001260492.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-06
Organism	Homo sapiens(human)
Product	radixin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ916738.1 and AP000901.5. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ916738.1, SRR1803611.153428.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GGGGACCCAA ACTGTATGCA TTGTTCCAGA TGCGCTCTTG CCAAAGCAGC 
ATAAAGCAAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247421.1
CDS	311..2125
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSSIKQM

Target ORF information:

RefSeq Version	NM_001260492.1
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260492.1

ORF Insert Sequence:

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GGGGACCCAA ACTGTATGCA TTGTTCCAGA TGCGCTCTTG CCAAAGCAGC 
ATAAAGCAAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_002906.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002897.1 Homo sapiens radixin (RDX), transcript variant 3, mRNA.

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CloneID	OHu26036
Clone ID Related Accession (Same CDS sequence)	NM_002906.3 , NM_002906.4
Accession Version	NM_002906.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1752bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-06
Organism	Homo sapiens(human)
Product	radixin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI600187.1, BC047109.1, BC002626.2, L02320.1, BX648536.1, CF265114.1 and CF124193.1. This sequence is a reference standard in the RefSeqGene project. On Apr 6, 2005 this sequence version replaced NM_002906.2. Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.117912.1, SRR1660809.110881.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467148 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002897.1
CDS	311..2062
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM

Target ORF information:

RefSeq Version	NM_002906.3
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002906.3

ORF Insert Sequence:

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_001260492.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001247421.1 Homo sapiens radixin (RDX), transcript variant 1, mRNA.

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CloneID	OHu12465
Clone ID Related Accession (Same CDS sequence)	NM_001260492.1 , NM_001260493.1 , NM_001260492.2
Accession Version	NM_001260492.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1815bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	radixin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ916738.1, AP002788.3 and CK299903.1. On Sep 20, 2019 this sequence version replaced NM_001260492.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ916738.1, SRR1803613.131475.1 [ECO:0000332] ##Evidence-Data-END##

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GGGGACCCAA ACTGTATGCA TTGTTCCAGA TGCGCTCTTG CCAAAGCAGC 
ATAAAGCAAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001247421.1
CDS	213..2027
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAMWGPKLYALFQMRSCQSSIKQM

Target ORF information:

RefSeq Version	NM_001260492.2
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001260492.2

ORF Insert Sequence:

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GGGGACCCAA ACTGTATGCA TTGTTCCAGA TGCGCTCTTG CCAAAGCAGC 
ATAAAGCAAA TGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RDX ( NM_002906.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002897.1 Homo sapiens radixin (RDX), transcript variant 3, mRNA.

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CloneID	OHu26036
Clone ID Related Accession (Same CDS sequence)	NM_002906.3 , NM_002906.4
Accession Version	NM_002906.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1752bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	radixin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002788.3 and AP000901.5. On Nov 27, 2019 this sequence version replaced NM_002906.3. Transcript Variant: This variant (3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002897.1
CDS	213..1964
Translation	MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM

Target ORF information:

RefSeq Version	NM_002906.4
Organism	Homo sapiens(human)
Definition	Homo sapiens radixin (RDX), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002906.4

ORF Insert Sequence:

ATGCCGAAAC CAATCAACGT AAGAGTAACT ACAATGGATG CTGAGCTGGA ATTTGCCATT 
CAGCCCAATA CAACTGGCAA ACAACTTTTT GACCAGGTGG TGAAAACAGT TGGTTTGCGT 
GAGGTCTGGT TTTTTGGGCT GCAGTATGTA GACAGCAAAG GTTATTCTAC ATGGCTTAAA 
CTAAATAAAA AGGTAACACA GCAGGATGTT AAAAAAGAGA ATCCTTTACA GTTCAAGTTT 
AGAGCTAAAT TCTTTCCTGA AGATGTTTCT GAGGAATTAA TTCAAGAAAT AACCCAGAGA 
CTCTTCTTCT TGCAAGTTAA AGAAGCCATC TTAAATGATG AGATATATTG CCCGCCAGAA 
ACTGCAGTTC TTTTGGCTTC CTATGCTGTC CAAGCCAAGT ATGGAGATTA CAATAAAGAG 
ATTCATAAGC CAGGCTACCT GGCTAATGAT AGACTCCTAC CCCAGCGTGT ATTGGAACAA 
CACAAACTAA CAAAAGAACA GTGGGAAGAA AGAATACAGA ACTGGCATGA AGAACATAGA 
GGAATGTTAA GGGAGGATTC TATGATGGAA TACCTGAAGA TTGCACAAGA TCTAGAAATG 
TATGGAGTCA ACTATTTTGA AATAAAAAAT AAAAAAGGAA CTGAATTGTG GCTAGGTGTT 
GATGCTTTGG GTCTGAATAT TTATGAGCAT GACGACAAGT TAACACCTAA AATTGGTTTT 
CCCTGGAGTG AAATCAGAAA TATTTCATTT AATGACAAAA AATTTGTTAT AAAGCCAATC 
GACAAAAAGG CACCTGATTT TGTGTTTTAT GCACCTCGTC TGAGAATCAA TAAGCGGATT 
TTGGCCTTAT GTATGGGAAA CCATGAACTA TACATGCGAA GAAGGAAGCC TGATACTATT 
GAAGTACAAC AGATGAAGGC TCAGGCTAGG GAGGAGAAAC ATCAGAAGCA GTTGGAAAGG 
GCACAATTAG AGAATGAAAA GAAGAAAAGA GAAATAGCAG AAAAGGAAAA GGAAAGAATA 
GAACGTGAAA AGGAAGAGCT AATGGAACGT CTAAAACAAA TTGAAGAGCA GACAATTAAA 
GCTCAGAAAG AACTAGAAGA ACAGACTCGA AAAGCTCTAG AACTGGATCA AGAACGAAAA 
CGAGCAAAAG AAGAAGCAGA ACGACTTGAA AAGGAGCGTC GAGCTGCTGA AGAGGCAAAG 
TCTGCCATAG CAAAACAAGC TGCCGACCAG ATGAAGAATC AGGAGCAGCT AGCAGCAGAA 
CTTGCTGAAT TCACTGCCAA GATTGCACTT CTAGAGGAAG CCAAGAAGAA AAAGGAAGAG 
GAAGCTACTG AGTGGCAACA CAAAGCTTTT GCAGCCCAGG AAGACTTGGA AAAGACCAAA 
GAAGAGTTAA AAACTGTGAT GTCTGCCCCC CCTCCACCTC CACCACCACC AGTCATTCCT 
CCAACAGAAA ACGAACATGA TGAACACGAT GAGAATAATG CTGAAGCTAG TGCTGAATTA 
TCAAATGAAG GGGTAATGAA CCATAGAAGC GAGGAAGAAC GTGTAACCGA AACACAGAAA 
AATGAGCGTG TTAAGAAGCA ACTTCAGGCA TTAAGTTCAG AATTAGCCCA AGCCAGAGAT 
GAAACCAAGA AAACACAAAA TGATGTTCTT CATGCTGAGA ATGTTAAAGC AGGCCGTGAT 
AAGTACAAGA CTCTGCGACA GATTCGACAA GGCAATACAA AGCAGCGTAT CGATGAGTTT 
GAAGCAATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dynamics and function of ERM proteins during cytokinesis in human cells.
FEBS letters591(20)3296-3309(2017 Oct)
Hiruma S,Kamasaki T,Otomo K,Nemoto T,Uehara R

CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.
Oncotarget7(48)78242-78254(2016 Nov)
Riecken LB,Zoch A,Wiehl U,Reichert S,Scholl I,Cui Y,Ziemer M,Anderegg U,Hagel C,Morrison H

Knockdown of Radixin Suppresses Gastric Cancer Metastasis In Vitro by Up-Regulation of E-Cadherin via NF-?B/Snail Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology39(6)2509-2521(2016)
Zhu YW,Yan JK,Li JJ,Ou YM,Yang Q

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RDX cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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