GNB4 cDNA ORF clone, Homo sapiens(human)

The following GNB4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GNB4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu21810 NM_021629.4
Latest version!
Homo sapiens G protein subunit beta 4 (GNB4), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
OHu21810 XM_006713721.2
Latest version!
Homo sapiens G protein subunit beta 4 (GNB4), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu21810 XM_005247692.2
Latest version!
Homo sapiens G protein subunit beta 4 (GNB4), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
View Old Accession Versions >>
OHu21810 NM_021629.3 Homo sapiens G protein subunit beta 4 (GNB4), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu21810
    Clone ID Related Accession (Same CDS sequence) XM_005247692.2 , XM_006713721.2 , NM_021629.4 , NM_021629.3
    Accession Version NM_021629.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1023bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-30
    Organism Homo sapiens(human)
    Product guanine nucleotide-binding protein subunit beta-4
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007620.30. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_021629.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.177602.1, SRR1803614.226704.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000232564.8/ ENSP00000232564.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_067642.1
    CDS168..1190
    Translation

    Target ORF information:

    RefSeq Version NM_021629.4
    Organism Homo sapiens(human)
    Definition Homo sapiens G protein subunit beta 4 (GNB4), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_021629.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu21810
    Clone ID Related Accession (Same CDS sequence) XM_005247692.2 , XM_006713721.2 , NM_021629.4 , NM_021629.3
    Accession Version NM_021629.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1023bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-12-10
    Organism Homo sapiens(human)
    Product guanine nucleotide-binding protein subunit beta-4
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007620.30. This sequence is a reference standard in the RefSeqGene project. On Mar 21, 2007 this sequence version replaced NM_021629.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001890.1, SRR1803614.177602.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_067642.1
    CDS281..1303
    Translation

    Target ORF information:

    RefSeq Version NM_021629.3
    Organism Homo sapiens(human)
    Definition Homo sapiens G protein subunit beta 4 (GNB4), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_021629.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu21810
    Clone ID Related Accession (Same CDS sequence) XM_005247692.2 , XM_006713721.2 , NM_021629.4 , NM_021629.3
    Accession Version XM_005247692.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1023bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product guanine nucleotide-binding protein subunit beta-4 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005247692.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_005247749.1
    CDS202..1224
    Translation

    Target ORF information:

    RefSeq Version XM_005247692.2
    Organism Homo sapiens(human)
    Definition Homo sapiens G protein subunit beta 4 (GNB4), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_005247692.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu21810
    Clone ID Related Accession (Same CDS sequence) XM_005247692.2 , XM_006713721.2 , NM_021629.4 , NM_021629.3
    Accession Version XM_006713721.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1023bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product guanine nucleotide-binding protein subunit beta-4 isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006713721.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_006713784.1
    CDS212..1234
    Translation

    Target ORF information:

    RefSeq Version XM_006713721.2
    Organism Homo sapiens(human)
    Definition Homo sapiens G protein subunit beta 4 (GNB4), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_006713721.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAGCGAAC TGGAACAGTT GAGGCAAGAA GCAGAACAAC TGCGGAATCA GATTCAGGAT 
    GCTCGGAAAG CATGTAATGA TGCAACGCTT GTTCAGATTA CATCAAATAT GGACTCTGTG
    GGTCGAATAC AAATGCGAAC AAGACGTACA CTGAGGGGCC ACCTAGCTAA AATCTATGCT
    ATGCATTGGG GATACGATTC CAGGCTGCTA GTCAGTGCTT CTCAAGATGG AAAATTAATT
    ATTTGGGATA GCTATACAAC AAATAAGATG CATGCTATTC CTTTGAGGTC CTCCTGGGTG
    ATGACCTGTG CTTATGCTCC CTCTGGTAAT TATGTTGCCT GTGGAGGCTT GGACAACATC
    TGCTCTATAT ATAACTTAAA GACCAGAGAG GGAAATGTGA GAGTAAGCCG AGAGTTGCCA
    GGTCACACAG GGTACTTGTC CTGCTGTCGT TTTTTAGATG ACAGCCAAAT TGTTACAAGT
    TCAGGAGATA CAACTTGTGC TTTATGGGAC ATCGAAACTG CCCAGCAGAC CACCACATTC
    ACTGGGCATT CTGGAGATGT GATGAGTCTT TCTTTGAGTC CTGACATGAG GACTTTTGTT
    TCTGGTGCTT GTGATGCCTC TTCCAAATTA TGGGATATTC GAGATGGAAT GTGTAGACAG
    TCTTTCACGG GACATGTCTC AGATATCAAT GCTGTCAGTT TTTTCCCAAA TGGATATGCC
    TTCGCCACTG GCTCTGATGA TGCCACTTGC CGGCTCTTTG ACCTTCGTGC AGATCAAGAG
    TTATTATTGT ATTCTCATGA CAATATCATC TGTGGAATCA CTTCTGTAGC CTTCTCAAAA
    AGTGGGCGTC TCTTGTTGGC TGGTTACGAT GACTTTAATT GTAATGTATG GGACACGCTA
    AAAGGAGATC GTGCAGGTGT CCTTGCTGGT CATGACAACC GTGTGAGCTG CTTAGGTGTA
    ACTGATGATG GCATGGCTGT GGCAACAGGC TCTTGGGACA GTTTTCTTAG AATCTGGAAT
    TAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    A novel missense variant (Gln220Arg) of GNB4 encoding guanine nucleotide-binding protein, subunit beta-4 in a Japanese family with autosomal dominant motor and sensory neuropathy.
    European journal of medical genetics60(9)474-478(2017 Sep)
    Miura S,Morikawa T,Fujioka R,Noda K,Kosaka K,Taniwaki T,Shibata H


    G?4?1 as a modulator of M3 muscarinic receptor signalling and novel roles of G?1 subunits in the modulation of cellular signalling.
    Cellular signalling27(8)1597-608(2015 Aug)
    Khan SM,Min A,Gora S,Houranieh GM,Campden R,Robitaille M,Trieu P,P?trin D,Jacobi AM,Behlke MA,Angers S,H?bert TE


    Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
    Nature genetics45(6)621-31(2013 Jun)
    den Hoed M,Eijgelsheim M,Esko T,Brundel BJ,Peal DS,Evans DM,Nolte IM,Segr? AV,Holm H,Handsaker RE,Westra HJ,Johnson T,Isaacs A,Yang J,Lundby A,Zhao JH,Kim YJ,Go MJ,Almgren P,Bochud M,Boucher G,Cornelis MC,Gudbjartsson D,Hadley D,van der Harst P,Hayward C,den Heijer M,Igl W,Jackson AU,Kutalik Z,Luan J,Kemp JP,Kristiansson K,Ladenvall C,Lorentzon M,Montasser ME,Njajou OT,O'Reilly PF,Padmanabhan S,St Pourcain B,Rankinen T,Salo P,Tanaka T,Timpson NJ,Vitart V,Waite L,Wheeler W,Zhang W,Draisma HH,Feitosa MF,Kerr KF,Lind PA,Mihailov E,Onland-Moret NC,Song C,Weedon MN,Xie W,Yengo L,Absher D,Albert CM,Alonso A,Arking DE,de Bakker PI,Balkau B,Barlassina C,Benaglio P,Bis JC,Bouatia-Naji N,Brage S,Chanock SJ,Chines PS,Chung M,Darbar D,Dina C,D?rr M,Elliott P,Felix SB,Fischer K,Fuchsberger C,de Geus EJ,Goyette P,Gudnason V,Harris TB,Hartikainen AL,Havulinna AS,Heckbert SR,Hicks AA,Hofman A,Holewijn S,Hoogstra-Berends F,Hottenga JJ,Jensen MK,Johansson A,Junttila J,K??b S,Kanon B,Ketkar S,Khaw KT,Knowles JW,Kooner AS,Kors JA,Kumari M,Milani L,Laiho P,Lakatta EG,Langenberg C,Leusink M,Liu Y,Luben RN,Lunetta KL,Lynch SN,Markus MR,Marques-Vidal P,Mateo Leach I,McArdle WL,McCarroll SA,Medland SE,Miller KA,Montgomery GW,Morrison AC,M?ller-Nurasyid M,Navarro P,Nelis M,O'Connell JR,O'Donnell CJ,Ong KK,Newman AB,Peters A,Polasek O,Pouta A,Pramstaller PP,Psaty BM,Rao DC,Ring SM,Rossin EJ,Rudan D,Sanna S,Scott RA,Sehmi JS,Sharp S,Shin JT,Singleton AB,Smith AV,Soranzo N,Spector TD,Stewart C,Stringham HM,Tarasov KV,Uitterlinden AG,Vandenput L,Hwang SJ,Whitfield JB,Wijmenga C,Wild SH,Willemsen G,Wilson JF,Witteman JC,Wong A,Wong Q,Jamshidi Y,Zitting P,Boer JM,Boomsma DI,Borecki IB,van Duijn CM,Ekelund U,Forouhi NG,Froguel P,Hingorani A,Ingelsson E,Kivimaki M,Kronmal RA,Kuh D,Lind L,Martin NG,Oostra BA,Pedersen NL,Quertermous T,Rotter JI,van der Schouw YT,Verschuren WM,Walker M,Albanes D,Arnar DO,Assimes TL,Bandinelli S,Boehnke M,de Boer RA,Bouchard C,Caulfield WL,Chambers JC,Curhan G,Cusi D,Eriksson J,Ferrucci L,van Gilst WH,Glorioso N,de Graaf J,Groop L,Gyllensten U,Hsueh WC,Hu FB,Huikuri HV,Hunter DJ,Iribarren C,Isomaa B,Jarvelin MR,Jula A,K?h?nen M,Kiemeney LA,van der Klauw MM,Kooner JS,Kraft P,Iacoviello L,Lehtim?ki T,Lokki ML,Mitchell BD,Navis G,Nieminen MS,Ohlsson C,Poulter NR,Qi L,Raitakari OT,Rimm EB,Rioux JD,Rizzi F,Rudan I,Salomaa V,Sever PS,Shields DC,Shuldiner AR,Sinisalo J,Stanton AV,Stolk RP,Strachan DP,Tardif JC,Thorsteinsdottir U,Tuomilehto J,van Veldhuisen DJ,Virtamo J,Viikari J,Vollenweider P,Waeber G,Widen E,Cho YS,Olsen JV,Visscher PM,Willer C,Franke L,,,Erdmann J,Thompson JR,,Pfeufer A,,Sotoodehnia N,,Newton-Cheh C,,Ellinor PT,Stricker BH,Metspalu A,Perola M,Beckmann JS,Smith GD,Stefansson K,Wareham NJ,Munroe PB,Sibon OC,Milan DJ,Snieder H,Samani NJ,Loos RJ


    Exome sequencing identifies GNB4 mutations as a cause of dominant intermediate Charcot-Marie-Tooth disease.
    American journal of human genetics92(3)422-30(2013 Mar)
    Soong BW,Huang YH,Tsai PC,Huang CC,Pan HC,Lu YC,Chien HJ,Liu TT,Chang MH,Lin KP,Tu PH,Kao LS,Lee YC