RBBP7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RBBP7
Entrez Gene ID	5931
Full Name	RB binding protein 7, chromatin remodeling factor
Synonyms	RbAp46
General protein information	Preferred Names RB binding protein 7, chromatin remodeling factor Names histone-binding protein RBBP7 G1/S transition control protein-binding protein RbAp46 RBBP-7 histone acetyltransferase type B subunit 2 nucleosome-remodeling factor subunit RBAP46 retinoblastoma-binding protein 7 retinoblastoma-binding protein RbAp46 retinoblastoma-binding protein p46
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp22.2
Summary	This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
Disorder MIM:	300825

mRNA and Protein(s)

mRNA	Protein	Name
NM_002893.3	NP_002884.1	histone-binding protein RBBP7 isoform 2
NM_001198719.1	NP_001185648.1	histone-binding protein RBBP7 isoform 1
NM_002893.4	NP_002884.1	histone-binding protein RBBP7 isoform 2
NM_001198719.2	NP_001185648.1	histone-binding protein RBBP7 isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RBBP7	XP_849201.1
Bos taurus (cattle)	RBBP7	NP_001029810.1
Pan troglodytes (chimpanzee)	RBBP7	XP_003953985.1
	RBBP7	XP_001103461.1
Mus musculus (house mouse)	Rbbp7	NP_033057.3
Xenopus tropicalis (tropical clawed frog)	rbbp7	NP_989285.1
Homo sapiens (human)	RBBP7	NP_001185648.1
Danio rerio (zebrafish)	rbb4l	NP_997775.1
Rattus norvegicus (Norway rat)	Rbbp7	NP_114004.1
Gallus gallus (chicken)	RBBP7	NP_990001.1

Gene Ontology
Bibliography

Related articles in PubMed

Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.
Moody RR, Lo MC, Meagher JL, Lin CC, Stevers NO, Tinsley SL, Jung I, Matvekas A, Stuckey JA, Sun D
The Journal of biological chemistry(2017 Dec)

Expression, purification and characterization of the human MTA2-RBBP7 complex.
Brasen C, Dorosz J, Wiuf A, Boesen T, Mirza O, Gajhede M
Biochimica et biophysica acta1865(5)531-538(2017 05)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together with previous findings this suggests, that MTA-RBBP is a stable complex, with a central role in the initial assembly of the human NuRD complex.
Title: Expression, purification and characterization of the human MTA2-RBBP7 complex.

AMPK phosphorylates DNMT1, RBBP7, and HAT1 and increases interactions of DNMT1, RBBP7, and HAT1.
Title: AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1.

Results show a novel interaction of the Lsm4 RGG domain with HAT1 and RBBP7, leading to the possibility of a posttranslational modifications network involved in mRNP regulation.
Title: The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation.

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/RBBP7.
Title: The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.

NKX6.1 directly enhances the mRNA level of E-cadherin by recruiting BAF155 coactivator and represses that of vimentin and N-cadherin by recruiting RBBP7 (retinoblastoma binding protein 7) corepressor.
Title: NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition.

The following RBBP7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RBBP7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05778	NM_001198719.2 Latest version!	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu08175	NM_002893.4 Latest version!	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu08175	NM_002893.3	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu05778	NM_001198719.1	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RBBP7 ( NM_001198719.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185648.1 Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05778
Clone ID Related Accession (Same CDS sequence)	NM_001198719.1 , NM_001198719.2
Accession Version	NM_001198719.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	histone-binding protein RBBP7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA924163.1, AK091911.1 and BQ775345.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.120101.1, AK091911.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCG AGGCGGGCGT CGTGGGAGCT GGGGCCTCCC CTGATGGGGA TTGGAGAGAC 
CAGGCCTGTG GGCTTCTGCT ACACGTGCAT TTGTCTTCCC GACTGGGTCG CGCAGCCCCT 
GTACGTACAG GTCGTCATCT TAGAACAGTG TTTGAAGATA CTGTGGAGGA GCGTGTCATC 
AATGAAGAAT ATAAAATCTG GAAGAAGAAT ACACCGTTTC TATATGACCT GGTTATGACC 
CATGCTCTTC AGTGGCCCAG TCTTACCGTT CAGTGGCTTC CTGAAGTGAC TAAACCTGAA 
GGAAAAGATT ATGCCCTTCA TTGGCTAGTG CTGGGGACTC ATACGTCTGA TGAGCAGAAT 
CATCTGGTGG TTGCTCGAGT ACATATTCCC AATGATGATG CACAGTTTGA TGCTTCCCAT 
TGTGACAGTG ACAAGGGTGA ATTTGGTGGC TTTGGTTCTG TAACAGGAAA AATTGAATGT 
GAAATTAAAA TCAATCACGA AGGAGAAGTA AACCGTGCTC GTTACATGCC GCAGAATCCT 
CACATCATTG CTACAAAAAC ACCATCTTCT GATGTGTTGG TTTTTGACTA TACAAAACAC 
CCTGCTAAAC CAGACCCAAG TGGAGAATGT AATCCTGATC TCAGATTAAG AGGTCACCAG 
AAGGAAGGCT ATGGTCTCTC CTGGAATTCA AATTTGAGTG GACATCTCCT AAGTGCATCT 
GATGACCATA CTGTTTGTCT GTGGGATATA AACGCAGGAC CAAAAGAAGG CAAAATTGTG 
GATGCTAAAG CCATCTTTAC TGGCCACTCA GCTGTTGTAG AGGATGTGGC CTGGCACCTG 
CTGCACGAGT CATTGTTTGG ATCTGTTGCT GATGATCAGA AACTTATGAT ATGGGACACC 
AGGTCCAATA CCACCTCCAA GCCGAGTCAC TTGGTGGATG CGCACACTGC CGAAGTCAAC 
TGCCTCTCAT TCAATCCCTA CAGCGAATTT ATTCTAGCCA CCGGCTCTGC GGATAAGACC 
GTAGCTTTAT GGGATCTGCG TAACTTAAAA TTAAAACTCC ATACCTTCGA ATCTCATAAA 
GATGAAATTT TCCAGGTCCA CTGGTCTCCA CATAATGAAA CTATTCTGGC TTCAAGTGGT 
ACTGACCGCC GCCTGAATGT GTGGGATTTA AGTAAAATTG GGGAAGAACA ATCAGCAGAA 
GATGCAGAAG ATGGGCCTCC AGAACTCCTG TTTATTCATG GAGGACACAC TGCTAAGATT 
TCAGATTTTA GCTGGAACCC CAATGAGCCT TGGGTCATTT GCTCAGTGTC TGAGGATAAC 
ATCATGCAGA TATGGCAAAT GGCTGAAAAT ATTTACAATG ATGAAGAGTC AGATGTCACG 
ACATCCGAAC TGGAGGGACA AGGATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185648.1
CDS	215..1624
Translation	MAAEAGVVGAGASPDGDWRDQACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS

Target ORF information:

RefSeq Version	NM_001198719.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198719.1

ORF Insert Sequence:

ATGGCTGCCG AGGCGGGCGT CGTGGGAGCT GGGGCCTCCC CTGATGGGGA TTGGAGAGAC 
CAGGCCTGTG GGCTTCTGCT ACACGTGCAT TTGTCTTCCC GACTGGGTCG CGCAGCCCCT 
GTACGTACAG GTCGTCATCT TAGAACAGTG TTTGAAGATA CTGTGGAGGA GCGTGTCATC 
AATGAAGAAT ATAAAATCTG GAAGAAGAAT ACACCGTTTC TATATGACCT GGTTATGACC 
CATGCTCTTC AGTGGCCCAG TCTTACCGTT CAGTGGCTTC CTGAAGTGAC TAAACCTGAA 
GGAAAAGATT ATGCCCTTCA TTGGCTAGTG CTGGGGACTC ATACGTCTGA TGAGCAGAAT 
CATCTGGTGG TTGCTCGAGT ACATATTCCC AATGATGATG CACAGTTTGA TGCTTCCCAT 
TGTGACAGTG ACAAGGGTGA ATTTGGTGGC TTTGGTTCTG TAACAGGAAA AATTGAATGT 
GAAATTAAAA TCAATCACGA AGGAGAAGTA AACCGTGCTC GTTACATGCC GCAGAATCCT 
CACATCATTG CTACAAAAAC ACCATCTTCT GATGTGTTGG TTTTTGACTA TACAAAACAC 
CCTGCTAAAC CAGACCCAAG TGGAGAATGT AATCCTGATC TCAGATTAAG AGGTCACCAG 
AAGGAAGGCT ATGGTCTCTC CTGGAATTCA AATTTGAGTG GACATCTCCT AAGTGCATCT 
GATGACCATA CTGTTTGTCT GTGGGATATA AACGCAGGAC CAAAAGAAGG CAAAATTGTG 
GATGCTAAAG CCATCTTTAC TGGCCACTCA GCTGTTGTAG AGGATGTGGC CTGGCACCTG 
CTGCACGAGT CATTGTTTGG ATCTGTTGCT GATGATCAGA AACTTATGAT ATGGGACACC 
AGGTCCAATA CCACCTCCAA GCCGAGTCAC TTGGTGGATG CGCACACTGC CGAAGTCAAC 
TGCCTCTCAT TCAATCCCTA CAGCGAATTT ATTCTAGCCA CCGGCTCTGC GGATAAGACC 
GTAGCTTTAT GGGATCTGCG TAACTTAAAA TTAAAACTCC ATACCTTCGA ATCTCATAAA 
GATGAAATTT TCCAGGTCCA CTGGTCTCCA CATAATGAAA CTATTCTGGC TTCAAGTGGT 
ACTGACCGCC GCCTGAATGT GTGGGATTTA AGTAAAATTG GGGAAGAACA ATCAGCAGAA 
GATGCAGAAG ATGGGCCTCC AGAACTCCTG TTTATTCATG GAGGACACAC TGCTAAGATT 
TCAGATTTTA GCTGGAACCC CAATGAGCCT TGGGTCATTT GCTCAGTGTC TGAGGATAAC 
ATCATGCAGA TATGGCAAAT GGCTGAAAAT ATTTACAATG ATGAAGAGTC AGATGTCACG 
ACATCCGAAC TGGAGGGACA AGGATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP7 ( NM_001198719.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185648.1 Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05778
Clone ID Related Accession (Same CDS sequence)	NM_001198719.1 , NM_001198719.2
Accession Version	NM_001198719.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1410bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	histone-binding protein RBBP7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL929302.16, DA924163.1, AK091911.1 and BQ775345.1. On Jun 2, 2019 this sequence version replaced NM_001198719.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.64055.1, AK091911.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCCG AGGCGGGCGT CGTGGGAGCT GGGGCCTCCC CTGATGGGGA TTGGAGAGAC 
CAGGCCTGTG GGCTTCTGCT ACACGTGCAT TTGTCTTCCC GACTGGGTCG CGCAGCCCCT 
GTACGTACAG GTCGTCATCT TAGAACAGTG TTTGAAGATA CTGTGGAGGA GCGTGTCATC 
AATGAAGAAT ATAAAATCTG GAAGAAGAAT ACACCGTTTC TATATGACCT GGTTATGACC 
CATGCTCTTC AGTGGCCCAG TCTTACCGTT CAGTGGCTTC CTGAAGTGAC TAAACCTGAA 
GGAAAAGATT ATGCCCTTCA TTGGCTAGTG CTGGGGACTC ATACGTCTGA TGAGCAGAAT 
CATCTGGTGG TTGCTCGAGT ACATATTCCC AATGATGATG CACAGTTTGA TGCTTCCCAT 
TGTGACAGTG ACAAGGGTGA ATTTGGTGGC TTTGGTTCTG TAACAGGAAA AATTGAATGT 
GAAATTAAAA TCAATCACGA AGGAGAAGTA AACCGTGCTC GTTACATGCC GCAGAATCCT 
CACATCATTG CTACAAAAAC ACCATCTTCT GATGTGTTGG TTTTTGACTA TACAAAACAC 
CCTGCTAAAC CAGACCCAAG TGGAGAATGT AATCCTGATC TCAGATTAAG AGGTCACCAG 
AAGGAAGGCT ATGGTCTCTC CTGGAATTCA AATTTGAGTG GACATCTCCT AAGTGCATCT 
GATGACCATA CTGTTTGTCT GTGGGATATA AACGCAGGAC CAAAAGAAGG CAAAATTGTG 
GATGCTAAAG CCATCTTTAC TGGCCACTCA GCTGTTGTAG AGGATGTGGC CTGGCACCTG 
CTGCACGAGT CATTGTTTGG ATCTGTTGCT GATGATCAGA AACTTATGAT ATGGGACACC 
AGGTCCAATA CCACCTCCAA GCCGAGTCAC TTGGTGGATG CGCACACTGC CGAAGTCAAC 
TGCCTCTCAT TCAATCCCTA CAGCGAATTT ATTCTAGCCA CCGGCTCTGC GGATAAGACC 
GTAGCTTTAT GGGATCTGCG TAACTTAAAA TTAAAACTCC ATACCTTCGA ATCTCATAAA 
GATGAAATTT TCCAGGTCCA CTGGTCTCCA CATAATGAAA CTATTCTGGC TTCAAGTGGT 
ACTGACCGCC GCCTGAATGT GTGGGATTTA AGTAAAATTG GGGAAGAACA ATCAGCAGAA 
GATGCAGAAG ATGGGCCTCC AGAACTCCTG TTTATTCATG GAGGACACAC TGCTAAGATT 
TCAGATTTTA GCTGGAACCC CAATGAGCCT TGGGTCATTT GCTCAGTGTC TGAGGATAAC 
ATCATGCAGA TATGGCAAAT GGCTGAAAAT ATTTACAATG ATGAAGAGTC AGATGTCACG 
ACATCCGAAC TGGAGGGACA AGGATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185648.1
CDS	223..1632
Translation	MAAEAGVVGAGASPDGDWRDQACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS

Target ORF information:

RefSeq Version	NM_001198719.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198719.2

ORF Insert Sequence:

ATGGCTGCCG AGGCGGGCGT CGTGGGAGCT GGGGCCTCCC CTGATGGGGA TTGGAGAGAC 
CAGGCCTGTG GGCTTCTGCT ACACGTGCAT TTGTCTTCCC GACTGGGTCG CGCAGCCCCT 
GTACGTACAG GTCGTCATCT TAGAACAGTG TTTGAAGATA CTGTGGAGGA GCGTGTCATC 
AATGAAGAAT ATAAAATCTG GAAGAAGAAT ACACCGTTTC TATATGACCT GGTTATGACC 
CATGCTCTTC AGTGGCCCAG TCTTACCGTT CAGTGGCTTC CTGAAGTGAC TAAACCTGAA 
GGAAAAGATT ATGCCCTTCA TTGGCTAGTG CTGGGGACTC ATACGTCTGA TGAGCAGAAT 
CATCTGGTGG TTGCTCGAGT ACATATTCCC AATGATGATG CACAGTTTGA TGCTTCCCAT 
TGTGACAGTG ACAAGGGTGA ATTTGGTGGC TTTGGTTCTG TAACAGGAAA AATTGAATGT 
GAAATTAAAA TCAATCACGA AGGAGAAGTA AACCGTGCTC GTTACATGCC GCAGAATCCT 
CACATCATTG CTACAAAAAC ACCATCTTCT GATGTGTTGG TTTTTGACTA TACAAAACAC 
CCTGCTAAAC CAGACCCAAG TGGAGAATGT AATCCTGATC TCAGATTAAG AGGTCACCAG 
AAGGAAGGCT ATGGTCTCTC CTGGAATTCA AATTTGAGTG GACATCTCCT AAGTGCATCT 
GATGACCATA CTGTTTGTCT GTGGGATATA AACGCAGGAC CAAAAGAAGG CAAAATTGTG 
GATGCTAAAG CCATCTTTAC TGGCCACTCA GCTGTTGTAG AGGATGTGGC CTGGCACCTG 
CTGCACGAGT CATTGTTTGG ATCTGTTGCT GATGATCAGA AACTTATGAT ATGGGACACC 
AGGTCCAATA CCACCTCCAA GCCGAGTCAC TTGGTGGATG CGCACACTGC CGAAGTCAAC 
TGCCTCTCAT TCAATCCCTA CAGCGAATTT ATTCTAGCCA CCGGCTCTGC GGATAAGACC 
GTAGCTTTAT GGGATCTGCG TAACTTAAAA TTAAAACTCC ATACCTTCGA ATCTCATAAA 
GATGAAATTT TCCAGGTCCA CTGGTCTCCA CATAATGAAA CTATTCTGGC TTCAAGTGGT 
ACTGACCGCC GCCTGAATGT GTGGGATTTA AGTAAAATTG GGGAAGAACA ATCAGCAGAA 
GATGCAGAAG ATGGGCCTCC AGAACTCCTG TTTATTCATG GAGGACACAC TGCTAAGATT 
TCAGATTTTA GCTGGAACCC CAATGAGCCT TGGGTCATTT GCTCAGTGTC TGAGGATAAC 
ATCATGCAGA TATGGCAAAT GGCTGAAAAT ATTTACAATG ATGAAGAGTC AGATGTCACG 
ACATCCGAAC TGGAGGGACA AGGATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP7 ( NM_002893.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002884.1 Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08175
Clone ID Related Accession (Same CDS sequence)	NM_002893.3 , NM_002893.4
Accession Version	NM_002893.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	histone-binding protein RBBP7 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB460068.1, BC114501.1, AL929302.16 and CN414343.1. On Nov 7, 2008 this sequence version replaced NM_002893.2. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.714248.1, SRR1803614.104875.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA AAGAGATGTT TGAAGATACT GTGGAGGAGC GTGTCATCAA TGAAGAATAT 
AAAATCTGGA AGAAGAATAC ACCGTTTCTA TATGACCTGG TTATGACCCA TGCTCTTCAG 
TGGCCCAGTC TTACCGTTCA GTGGCTTCCT GAAGTGACTA AACCTGAAGG AAAAGATTAT 
GCCCTTCATT GGCTAGTGCT GGGGACTCAT ACGTCTGATG AGCAGAATCA TCTGGTGGTT 
GCTCGAGTAC ATATTCCCAA TGATGATGCA CAGTTTGATG CTTCCCATTG TGACAGTGAC 
AAGGGTGAAT TTGGTGGCTT TGGTTCTGTA ACAGGAAAAA TTGAATGTGA AATTAAAATC 
AATCACGAAG GAGAAGTAAA CCGTGCTCGT TACATGCCGC AGAATCCTCA CATCATTGCT 
ACAAAAACAC CATCTTCTGA TGTGTTGGTT TTTGACTATA CAAAACACCC TGCTAAACCA 
GACCCAAGTG GAGAATGTAA TCCTGATCTC AGATTAAGAG GTCACCAGAA GGAAGGCTAT 
GGTCTCTCCT GGAATTCAAA TTTGAGTGGA CATCTCCTAA GTGCATCTGA TGACCATACT 
GTTTGTCTGT GGGATATAAA CGCAGGACCA AAAGAAGGCA AAATTGTGGA TGCTAAAGCC 
ATCTTTACTG GCCACTCAGC TGTTGTAGAG GATGTGGCCT GGCACCTGCT GCACGAGTCA 
TTGTTTGGAT CTGTTGCTGA TGATCAGAAA CTTATGATAT GGGACACCAG GTCCAATACC 
ACCTCCAAGC CGAGTCACTT GGTGGATGCG CACACTGCCG AAGTCAACTG CCTCTCATTC 
AATCCCTACA GCGAATTTAT TCTAGCCACC GGCTCTGCGG ATAAGACCGT AGCTTTATGG 
GATCTGCGTA ACTTAAAATT AAAACTCCAT ACCTTCGAAT CTCATAAAGA TGAAATTTTC 
CAGGTCCACT GGTCTCCACA TAATGAAACT ATTCTGGCTT CAAGTGGTAC TGACCGCCGC 
CTGAATGTGT GGGATTTAAG TAAAATTGGG GAAGAACAAT CAGCAGAAGA TGCAGAAGAT 
GGGCCTCCAG AACTCCTGTT TATTCATGGA GGACACACTG CTAAGATTTC AGATTTTAGC 
TGGAACCCCA ATGAGCCTTG GGTCATTTGC TCAGTGTCTG AGGATAACAT CATGCAGATA 
TGGCAAATGG CTGAAAATAT TTACAATGAT GAAGAGTCAG ATGTCACGAC ATCCGAACTG 
GAGGGACAAG GATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002884.1
CDS	359..1636
Translation	MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS

Target ORF information:

RefSeq Version	NM_002893.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002893.3

ORF Insert Sequence:

ATGGCGAGTA AAGAGATGTT TGAAGATACT GTGGAGGAGC GTGTCATCAA TGAAGAATAT 
AAAATCTGGA AGAAGAATAC ACCGTTTCTA TATGACCTGG TTATGACCCA TGCTCTTCAG 
TGGCCCAGTC TTACCGTTCA GTGGCTTCCT GAAGTGACTA AACCTGAAGG AAAAGATTAT 
GCCCTTCATT GGCTAGTGCT GGGGACTCAT ACGTCTGATG AGCAGAATCA TCTGGTGGTT 
GCTCGAGTAC ATATTCCCAA TGATGATGCA CAGTTTGATG CTTCCCATTG TGACAGTGAC 
AAGGGTGAAT TTGGTGGCTT TGGTTCTGTA ACAGGAAAAA TTGAATGTGA AATTAAAATC 
AATCACGAAG GAGAAGTAAA CCGTGCTCGT TACATGCCGC AGAATCCTCA CATCATTGCT 
ACAAAAACAC CATCTTCTGA TGTGTTGGTT TTTGACTATA CAAAACACCC TGCTAAACCA 
GACCCAAGTG GAGAATGTAA TCCTGATCTC AGATTAAGAG GTCACCAGAA GGAAGGCTAT 
GGTCTCTCCT GGAATTCAAA TTTGAGTGGA CATCTCCTAA GTGCATCTGA TGACCATACT 
GTTTGTCTGT GGGATATAAA CGCAGGACCA AAAGAAGGCA AAATTGTGGA TGCTAAAGCC 
ATCTTTACTG GCCACTCAGC TGTTGTAGAG GATGTGGCCT GGCACCTGCT GCACGAGTCA 
TTGTTTGGAT CTGTTGCTGA TGATCAGAAA CTTATGATAT GGGACACCAG GTCCAATACC 
ACCTCCAAGC CGAGTCACTT GGTGGATGCG CACACTGCCG AAGTCAACTG CCTCTCATTC 
AATCCCTACA GCGAATTTAT TCTAGCCACC GGCTCTGCGG ATAAGACCGT AGCTTTATGG 
GATCTGCGTA ACTTAAAATT AAAACTCCAT ACCTTCGAAT CTCATAAAGA TGAAATTTTC 
CAGGTCCACT GGTCTCCACA TAATGAAACT ATTCTGGCTT CAAGTGGTAC TGACCGCCGC 
CTGAATGTGT GGGATTTAAG TAAAATTGGG GAAGAACAAT CAGCAGAAGA TGCAGAAGAT 
GGGCCTCCAG AACTCCTGTT TATTCATGGA GGACACACTG CTAAGATTTC AGATTTTAGC 
TGGAACCCCA ATGAGCCTTG GGTCATTTGC TCAGTGTCTG AGGATAACAT CATGCAGATA 
TGGCAAATGG CTGAAAATAT TTACAATGAT GAAGAGTCAG ATGTCACGAC ATCCGAACTG 
GAGGGACAAG GATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP7 ( NM_002893.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002884.1 Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.

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CloneID	OHu08175
Clone ID Related Accession (Same CDS sequence)	NM_002893.3 , NM_002893.4
Accession Version	NM_002893.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	histone-binding protein RBBP7 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB460068.1, BC114501.1, AL929302.16 and CN414343.1. On Jun 2, 2019 this sequence version replaced NM_002893.3. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.112541.1, SRR1803613.49995.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGTA AAGAGATGTT TGAAGATACT GTGGAGGAGC GTGTCATCAA TGAAGAATAT 
AAAATCTGGA AGAAGAATAC ACCGTTTCTA TATGACCTGG TTATGACCCA TGCTCTTCAG 
TGGCCCAGTC TTACCGTTCA GTGGCTTCCT GAAGTGACTA AACCTGAAGG AAAAGATTAT 
GCCCTTCATT GGCTAGTGCT GGGGACTCAT ACGTCTGATG AGCAGAATCA TCTGGTGGTT 
GCTCGAGTAC ATATTCCCAA TGATGATGCA CAGTTTGATG CTTCCCATTG TGACAGTGAC 
AAGGGTGAAT TTGGTGGCTT TGGTTCTGTA ACAGGAAAAA TTGAATGTGA AATTAAAATC 
AATCACGAAG GAGAAGTAAA CCGTGCTCGT TACATGCCGC AGAATCCTCA CATCATTGCT 
ACAAAAACAC CATCTTCTGA TGTGTTGGTT TTTGACTATA CAAAACACCC TGCTAAACCA 
GACCCAAGTG GAGAATGTAA TCCTGATCTC AGATTAAGAG GTCACCAGAA GGAAGGCTAT 
GGTCTCTCCT GGAATTCAAA TTTGAGTGGA CATCTCCTAA GTGCATCTGA TGACCATACT 
GTTTGTCTGT GGGATATAAA CGCAGGACCA AAAGAAGGCA AAATTGTGGA TGCTAAAGCC 
ATCTTTACTG GCCACTCAGC TGTTGTAGAG GATGTGGCCT GGCACCTGCT GCACGAGTCA 
TTGTTTGGAT CTGTTGCTGA TGATCAGAAA CTTATGATAT GGGACACCAG GTCCAATACC 
ACCTCCAAGC CGAGTCACTT GGTGGATGCG CACACTGCCG AAGTCAACTG CCTCTCATTC 
AATCCCTACA GCGAATTTAT TCTAGCCACC GGCTCTGCGG ATAAGACCGT AGCTTTATGG 
GATCTGCGTA ACTTAAAATT AAAACTCCAT ACCTTCGAAT CTCATAAAGA TGAAATTTTC 
CAGGTCCACT GGTCTCCACA TAATGAAACT ATTCTGGCTT CAAGTGGTAC TGACCGCCGC 
CTGAATGTGT GGGATTTAAG TAAAATTGGG GAAGAACAAT CAGCAGAAGA TGCAGAAGAT 
GGGCCTCCAG AACTCCTGTT TATTCATGGA GGACACACTG CTAAGATTTC AGATTTTAGC 
TGGAACCCCA ATGAGCCTTG GGTCATTTGC TCAGTGTCTG AGGATAACAT CATGCAGATA 
TGGCAAATGG CTGAAAATAT TTACAATGAT GAAGAGTCAG ATGTCACGAC ATCCGAACTG 
GAGGGACAAG GATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002884.1
CDS	310..1587
Translation	MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS

Target ORF information:

RefSeq Version	NM_002893.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 7, chromatin remodeling factor (RBBP7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002893.4

ORF Insert Sequence:

ATGGCGAGTA AAGAGATGTT TGAAGATACT GTGGAGGAGC GTGTCATCAA TGAAGAATAT 
AAAATCTGGA AGAAGAATAC ACCGTTTCTA TATGACCTGG TTATGACCCA TGCTCTTCAG 
TGGCCCAGTC TTACCGTTCA GTGGCTTCCT GAAGTGACTA AACCTGAAGG AAAAGATTAT 
GCCCTTCATT GGCTAGTGCT GGGGACTCAT ACGTCTGATG AGCAGAATCA TCTGGTGGTT 
GCTCGAGTAC ATATTCCCAA TGATGATGCA CAGTTTGATG CTTCCCATTG TGACAGTGAC 
AAGGGTGAAT TTGGTGGCTT TGGTTCTGTA ACAGGAAAAA TTGAATGTGA AATTAAAATC 
AATCACGAAG GAGAAGTAAA CCGTGCTCGT TACATGCCGC AGAATCCTCA CATCATTGCT 
ACAAAAACAC CATCTTCTGA TGTGTTGGTT TTTGACTATA CAAAACACCC TGCTAAACCA 
GACCCAAGTG GAGAATGTAA TCCTGATCTC AGATTAAGAG GTCACCAGAA GGAAGGCTAT 
GGTCTCTCCT GGAATTCAAA TTTGAGTGGA CATCTCCTAA GTGCATCTGA TGACCATACT 
GTTTGTCTGT GGGATATAAA CGCAGGACCA AAAGAAGGCA AAATTGTGGA TGCTAAAGCC 
ATCTTTACTG GCCACTCAGC TGTTGTAGAG GATGTGGCCT GGCACCTGCT GCACGAGTCA 
TTGTTTGGAT CTGTTGCTGA TGATCAGAAA CTTATGATAT GGGACACCAG GTCCAATACC 
ACCTCCAAGC CGAGTCACTT GGTGGATGCG CACACTGCCG AAGTCAACTG CCTCTCATTC 
AATCCCTACA GCGAATTTAT TCTAGCCACC GGCTCTGCGG ATAAGACCGT AGCTTTATGG 
GATCTGCGTA ACTTAAAATT AAAACTCCAT ACCTTCGAAT CTCATAAAGA TGAAATTTTC 
CAGGTCCACT GGTCTCCACA TAATGAAACT ATTCTGGCTT CAAGTGGTAC TGACCGCCGC 
CTGAATGTGT GGGATTTAAG TAAAATTGGG GAAGAACAAT CAGCAGAAGA TGCAGAAGAT 
GGGCCTCCAG AACTCCTGTT TATTCATGGA GGACACACTG CTAAGATTTC AGATTTTAGC 
TGGAACCCCA ATGAGCCTTG GGTCATTTGC TCAGTGTCTG AGGATAACAT CATGCAGATA 
TGGCAAATGG CTGAAAATAT TTACAATGAT GAAGAGTCAG ATGTCACGAC ATCCGAACTG 
GAGGGACAAG GATCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.
The Journal of biological chemistry(2017 Dec)
Moody RR,Lo MC,Meagher JL,Lin CC,Stevers NO,Tinsley SL,Jung I,Matvekas A,Stuckey JA,Sun D

Expression, purification and characterization of the human MTA2-RBBP7 complex.
Biochimica et biophysica acta1865(5)531-538(2017 05)
Brasen C,Dorosz J,Wiuf A,Boesen T,Mirza O,Gajhede M

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

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RBBP7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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