Gene Symbol | RBBP6 |
Entrez Gene ID | 5930 |
Full Name | RB binding protein 6, ubiquitin ligase |
Synonyms | MY038,P2P-R,PACT,RBQ-1,SNAMA |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |