KDM5A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KDM5A
Entrez Gene ID	5927
Full Name	lysine demethylase 5A
Synonyms	RBBP-2,RBBP2,RBP2
General protein information	Preferred Names lysine demethylase 5A Names lysine-specific demethylase 5A Jumonji, AT rich interactive domain 1A (RBP2-like) histone demethylase JARID1A jumonji/ARID domain-containing protein 1A lysine (K)-specific demethylase 5A retinoblastoma binding protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.33
Summary	This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013].
Disorder MIM:	180202

mRNA and Protein(s)

mRNA	Protein	Name
NM_001042603.2	NP_001036068.1	lysine-specific demethylase 5A
NM_001042603.3	NP_001036068.1	lysine-specific demethylase 5A

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	KDM5A	XP_005637389.1
Mus musculus (house mouse)	Kdm5a	NP_666109.2
Xenopus tropicalis (tropical clawed frog)	kdm5a	XP_002941946.2
Homo sapiens (human)	KDM5A	NP_001036068.1
Pan troglodytes (chimpanzee)	KDM5A	XP_003313474.1
Rattus norvegicus (Norway rat)	Kdm5a	NP_001264106.1
Gallus gallus (chicken)	KDM5A	XP_004937981.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004854	XP_314337.4
	KDM5A	XP_002798486.1
Drosophila melanogaster (fruit fly)	lid	NP_001245909.1
Bos taurus (cattle)	KDM5A	NP_001192554.1
Danio rerio (zebrafish)	kdm5a	XP_003201688.2

Gene Ontology
Bibliography

Related articles in PubMed

Dynamic site-specific recruitment of RBP2 by pocket protein p130 modulates H3K4 methylation on E2F-responsive promoters.
Zargar ZU, Kimidi MR, Tyagi S
Nucleic acids research46(1)174-188(2018 Jan)

Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
Dai B, Huang H, Guan F, Zhu G, Xiao Z, Mao B, Su H, Hu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie9972-80(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

KDM5A demethylates H3K4 to allow ZMYND8-NuRD to operate within damaged chromatin to repair DNA double strand breaks.
Title: Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.

KDM5A-mediated H3K4me3 modification participated in the etiology of osteoporosis and may provide new strategies to improve the clinical efficacy of BMP2 in osteoporotic conditions.
Title: KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis.

KDM5A 5A inhibitor blocks cancer cell growth and drug resistance
Title: Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.
Title: Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.

the radiation sensitivity observed following depletion of Jarid1A is not caused by a deficiency in repair of DNA double-strand breaks.
Title: Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair.

The following KDM5A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KDM5A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11481	NM_001042603.3 Latest version!	Homo sapiens lysine demethylase 5A (KDM5A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$659.50-$923.30 $1319.00
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OHu11481	NM_001042603.2	Homo sapiens lysine demethylase 5A (KDM5A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$659.50-$923.30 $1319.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KDM5A ( NM_001042603.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036068.1 Homo sapiens lysine demethylase 5A (KDM5A), mRNA.

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CloneID	OHu11481
Clone ID Related Accession (Same CDS sequence)	NM_001042603.2 , NM_001042603.3
Accession Version	NM_001042603.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	lysine-specific demethylase 5A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU182136.1, DA211439.1, AB209999.1 and AC007406.1. This sequence is a reference standard in the RefSeqGene project. On Aug 2, 2013 this sequence version replaced NM_001042603.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209999.1, SRR1803617.197173.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCG TGGGGCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC AGAGTGCCCC 
GTCTTTGAGC CGAGTTGGGA GGAGTTCACA GATCCGCTCA GCTTTATCGG CCGCATCCGG 
CCTTTGGCGG AGAAAACCGG CATCTGCAAA ATTCGGCCGC CCAAGGACTG GCAGCCTCCA 
TTTGCCTGTG AAGTAAAAAG CTTTCGTTTC ACTCCAAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CCAGAGTGAG ATTGGATTTC TTGGATCAAC TAGCAAAATT TTGGGAACTT 
CAAGGATCTA CTCTGAAGAT CCCTGTGGTA GAGAGAAAAA TCCTGGATCT GTATGCTTTG 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATGGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GTCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CATTATGAAA GAATTCTCTA CCCATATGAG CTTTTCCAGT CTGGTGTGAG CCTTATGGGT 
GTGCAGATGC CTAATTTAGA TCTTAAAGAA AAAGTGGAGC CTGAGGTTCT CAGCACTGAT 
ACCCAAACTT CCCCAGAGCC AGGCACAAGG ATGAACATTC TGCCGAAGAG AACAAGACGT 
GTGAAGACTC AGTCAGAATC TGGAGATGTG AGTAGAAACA CGGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGGCCCAA GGTTGTGGGC TTGGCAATGG GAACAAAAGA TAAAGAAGAT 
GAGGTCACCC GAAGACGAAA AGTTACCAAC AGGTCAGACG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GCACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGTAT GTTTTGTGGT 
CGGGGAAACA ATGAAGATAA ATTGCTTTTG TGTGATGGAT GTGATGACAG CTATCATACA 
TTTTGTCTAA TTCCTCCACT ACCTGATGTG CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTCGCCGAGG AATGTAGCAA ACCTCGAGAA GCCTTTGGAT TTGAACAAGC TGTACGAGAG 
TATACACTTC AGAGCTTTGG AGAGATGGCA GATAATTTTA AGTCTGATTA TTTTAATATG 
CCAGTCCATA TGGTTCCCAC AGAACTAGTA GAAAAGGAAT TTTGGCGGCT GGTAAGCAGC 
ATTGAAGAAG ATGTTATTGT GGAATATGGA GCAGATATCT CCTCAAAAGA CTTTGGAAGT 
GGATTTCCGG TGAAGGATGG GCGGAGAAAG ATTCTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTC CTGGAACAGT CTGTTCTTGC ACATATTAAT 
GTGGACATCT CTGGTATGAA AGTGCCGTGG CTCTATGTGG GAATGTGCTT CTCTTCTTTT 
TGCTGGCACA TTGAGGATCA CTGGAGTTAT TCCATCAACT ACTTGCACTG GGGGGAGCCA 
AAGACATGGT ATGGTGTGCC ATCTCATGCT GCAGAGCAAC TGGAGGAGGT GATGAGAGAG 
CTGGCCCCCG AGTTATTTGA ATCCCAGCCT GATCTTCTGC ATCAGTTAGT TACCATCATG 
AACCCCAACG TGCTAATGGA GCATGGTGTG CCTGTGTACA GGACCAATCA GTGTGCTGGC 
GAGTTTGTTG TGACATTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG CTACAACTTT 
GCTGAAGCTG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA ATGTGTAAAT 
CATTACCGAC GCCTAAGGCG CCACTGTGTC TTTTCACACG AGGAACTAAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTCTGCAA AGAATTGACT 
CTCATGACTG AAGAAGAAAC ACGATTAAGA GAGTCTGTTG TACAGATGGG TGTCCTGATG 
TCAGAAGAAG AAGTGTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACCACATGTT TTCTCTCTGC TCTCACATGT TCCTGTAATC CTGAGCGGCT TGTATGTCTC 
TACCATCCAA CTGATCTGTG CCCCTGCCCC ATGCAGAAGA AATGTCTTAG ATATCGCTAC 
CCATTAGAAG ACCTCCCTTC TCTGCTATAT GGTGTAAAAG TCAGGGCACA GTCCTATGAC 
ACTTGGGTCA GTCGTGTTAC AGAAGCATTG TCTGCTAACT TCAACCACAA AAAAGATTTG 
ATTGAATTGC GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAAC TCAGGGATGC TGTAAAAGAA GCTGAGACCT GTGCTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAGAA ACACAGACAG AGCCCAGATA GTGGGAGGAC TCGGACCAAA 
CTGACAGTGG AAGAATTGAA GGCCTTTGTC CAACAACTTT TTAGTCTTCC GTGTGTCATC 
AGCCAAGCTC GGCAAGTAAA GAATCTGCTA GATGATGTGG AAGAGTTTCA TGAACGTGCT 
CAGGAGGCCA TGATGGATGA AACCCCAGAT TCTTCCAAAC TCCAGATGTT GATAGATATG 
GGCTCTAGTC TCTATGTGGA ACTCCCTGAA TTACCACGAC TGAAGCAAGA GCTACAACAG 
GCTCGGTGGT TGGACGAAGT AAGACTGACC TTATCAGATC CGCAACAAGT CACTTTGGAT 
GTCATGAAGA AGCTGATAGA CTCTGGGGTA GGGTTGGCAC CCCACCATGC TGTGGAGAAA 
GCAATGGCTG AACTACAGGA GCTCCTTACA GTCTCTGAAC GATGGGAAGA AAAGGCTAAG 
GTCTGCCTAC AGGCAAGACC GAGGCACAGT GTGGCAAGTT TAGAAAGCAT TGTGAATGAA 
GCCAAGAACA TTCCAGCCTT TCTACCCAAT GTGTTGTCCT TGAAAGAAGC CTTACAAAAG 
GCTCGAGAAT GGACCGCTAA AGTGGAAGCT ATTCAGAGTG GCAGCAATTA CGCTTATTTG 
GAGCAGCTTG AGAGCTTGTC TGCGAAAGGA CGCCCTATTC CTGTGCGTCT TGAAGCACTG 
CCGCAAGTGG AATCACAGGT AGCAGCAGCA CGGGCATGGA GAGAACGGAC TGGGCGGACG 
TTTCTTAAGA AGAATTCTAG CCATACATTG TTACAGGTGC TGAGCCCCCG GACCGACATT 
GGTGTATATG GGAGTGGCAA AAATAGGAGG AAAAAAGTAA AAGAACTAAT AGAAAAAGAA 
AAAGAAAAGG ATCTGGACCT GGAGCCTCTG AGTGATCTGG AGGAAGGATT GGAGGAAACC 
AGAGATACAG CCATGGTGGT GGCAGTTTTC AAAGAACGGG AGCAAAAAGA GATTGAAGCC 
ATGCATTCTC TCAGAGCAGC CAACCTAGCC AAGATGACAA TGGTGGACCG CATAGAAGAA 
GTAAAATTTT GCATTTGCCG CAAGACAGCC AGTGGGTTTA TGCTACAGTG TGAGCTCTGC 
AAAGACTGGT TCCATAACAG CTGTGTTCCT CTTCCTAAAT CAAGTTCCCA AAAAAAAGGA 
TCCAGCTGGC AAGCTAAAGA AGTAAAATTC CTTTGCCCTC TTTGTATGCG GTCTCGAAGG 
CCCAGGCTAG AGACTATTCT GTCACTCCTG GTATCCCTTC AGAAGTTGCC CGTACGGTTG 
CCTGAAGGAG AGGCCCTGCA GTGTTTGACA GAACGTGCTA TGAGTTGGCA AGATAGAGCG 
CGGCAGGCTC TAGCCACAGA TGAACTATCC TCTGCCCTGG CCAAACTATC TGTGTTGAGC 
CAGCGTATGG TGGAACAGGC GGCTCGAGAA AAAACTGAAA AGATCATCAG TGCAGAACTC 
CAAAAAGCAG CTGCCAATCC AGACTTACAG GGACACTTAC CTAGTTTCCA GCAGTCTGCT 
TTTAACCGGG TGGTGAGCAG TGTGTCATCT TCTCCTCGAC AAACAATGGA CTATGATGAT 
GAAGAAACAG ACTCTGATGA AGACATTCGA GAGACATATG GCTACGACAT GAAGGACACA 
GCCAGTGTGA AGTCCTCTAG TAGTCTTGAA CCCAATCTTT TTTGTGATGA AGAGATTCCC 
ATCAAATCCG AGGAGGTGGT GACCCACATG TGGACAGCAC CTTCATTTTG TGCAGAGCAT 
GCTTATTCTT CTGCTTCTAA GAGTTGTTCT CAAGGTTCTA GCACCCCAAG GAAACAACCT 
CGGAAGAGCC CTTTGGTGCC CCGAAGTTTG GAACCTCCAG TGCTGGAGTT GTCACCTGGA 
GCTAAGGCAC AACTGGAAGA ACTTATGATG GTTGGAGATC TCCTGGAAGT ATCTCTGGAC 
GAGACTCAAC ACATATGGCG GATTTTGCAG GCCACACACC CACCCTCTGA AGACAGATTC 
TTGCATATCA TGGAGGATGA CAGCATGGAA GAGAAACCAC TAAAAGTGAA AGGAAAGGAC 
TCTTCAGAGA AGAAACGGAA ACGGAAGCTA GAAAAGGTAG AGCAACTTTT TGGAGAAGGA 
AAACAGAAGT CCAAGGAGTT AAAGAAAATG GACAAACCTA GAAAGAAGAA ATTAAAATTA 
GGTGCAGACA AATCAAAGGA GCTGAATAAA CTGGCCAAGA AACTAGCAAA AGAAGAAGAG 
AGAAAGAAAA AGAAGGAGAA GGCTGCTGCA GCCAAAGTTG AACTTGTGAA AGAGAGCACT 
GAAAAGAAAA GAGAGAAAAA GGTGCTGGAC ATCCCCTCAA AGTATGACTG GTCAGGAGCA 
GAGGAGTCTG ATGATGAGAA TGCTGTGTGC GCAGCACAGA ACTGCCAAAG GCCCTGCAAG 
GACAAGGTAG ACTGGGTACA ATGTGATGGT GGCTGTGATG AGTGGTTTCA TCAAGTTTGT 
GTGGGTGTAT CTCCAGAAAT GGCTGAAAAT GAAGATTACA TCTGTATAAA CTGTGCAAAG 
AAGCAGGGGC CAGTTAGCCC AGGTCCAGCA CCACCTCCTT CCTTCATAAT GAGCTACAAA 
CTACCAATGG AGGATCTTAA AGAGACCAGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036068.1
CDS	365..5437
Translation	MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQPRKSPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYKLPMEDLKETS

Target ORF information:

RefSeq Version	NM_001042603.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine demethylase 5A (KDM5A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042603.2

ORF Insert Sequence:

ATGGCGGGCG TGGGGCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC AGAGTGCCCC 
GTCTTTGAGC CGAGTTGGGA GGAGTTCACA GATCCGCTCA GCTTTATCGG CCGCATCCGG 
CCTTTGGCGG AGAAAACCGG CATCTGCAAA ATTCGGCCGC CCAAGGACTG GCAGCCTCCA 
TTTGCCTGTG AAGTAAAAAG CTTTCGTTTC ACTCCAAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CCAGAGTGAG ATTGGATTTC TTGGATCAAC TAGCAAAATT TTGGGAACTT 
CAAGGATCTA CTCTGAAGAT CCCTGTGGTA GAGAGAAAAA TCCTGGATCT GTATGCTTTG 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATGGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GTCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CATTATGAAA GAATTCTCTA CCCATATGAG CTTTTCCAGT CTGGTGTGAG CCTTATGGGT 
GTGCAGATGC CTAATTTAGA TCTTAAAGAA AAAGTGGAGC CTGAGGTTCT CAGCACTGAT 
ACCCAAACTT CCCCAGAGCC AGGCACAAGG ATGAACATTC TGCCGAAGAG AACAAGACGT 
GTGAAGACTC AGTCAGAATC TGGAGATGTG AGTAGAAACA CGGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGGCCCAA GGTTGTGGGC TTGGCAATGG GAACAAAAGA TAAAGAAGAT 
GAGGTCACCC GAAGACGAAA AGTTACCAAC AGGTCAGACG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GCACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGTAT GTTTTGTGGT 
CGGGGAAACA ATGAAGATAA ATTGCTTTTG TGTGATGGAT GTGATGACAG CTATCATACA 
TTTTGTCTAA TTCCTCCACT ACCTGATGTG CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTCGCCGAGG AATGTAGCAA ACCTCGAGAA GCCTTTGGAT TTGAACAAGC TGTACGAGAG 
TATACACTTC AGAGCTTTGG AGAGATGGCA GATAATTTTA AGTCTGATTA TTTTAATATG 
CCAGTCCATA TGGTTCCCAC AGAACTAGTA GAAAAGGAAT TTTGGCGGCT GGTAAGCAGC 
ATTGAAGAAG ATGTTATTGT GGAATATGGA GCAGATATCT CCTCAAAAGA CTTTGGAAGT 
GGATTTCCGG TGAAGGATGG GCGGAGAAAG ATTCTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTC CTGGAACAGT CTGTTCTTGC ACATATTAAT 
GTGGACATCT CTGGTATGAA AGTGCCGTGG CTCTATGTGG GAATGTGCTT CTCTTCTTTT 
TGCTGGCACA TTGAGGATCA CTGGAGTTAT TCCATCAACT ACTTGCACTG GGGGGAGCCA 
AAGACATGGT ATGGTGTGCC ATCTCATGCT GCAGAGCAAC TGGAGGAGGT GATGAGAGAG 
CTGGCCCCCG AGTTATTTGA ATCCCAGCCT GATCTTCTGC ATCAGTTAGT TACCATCATG 
AACCCCAACG TGCTAATGGA GCATGGTGTG CCTGTGTACA GGACCAATCA GTGTGCTGGC 
GAGTTTGTTG TGACATTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG CTACAACTTT 
GCTGAAGCTG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA ATGTGTAAAT 
CATTACCGAC GCCTAAGGCG CCACTGTGTC TTTTCACACG AGGAACTAAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTCTGCAA AGAATTGACT 
CTCATGACTG AAGAAGAAAC ACGATTAAGA GAGTCTGTTG TACAGATGGG TGTCCTGATG 
TCAGAAGAAG AAGTGTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACCACATGTT TTCTCTCTGC TCTCACATGT TCCTGTAATC CTGAGCGGCT TGTATGTCTC 
TACCATCCAA CTGATCTGTG CCCCTGCCCC ATGCAGAAGA AATGTCTTAG ATATCGCTAC 
CCATTAGAAG ACCTCCCTTC TCTGCTATAT GGTGTAAAAG TCAGGGCACA GTCCTATGAC 
ACTTGGGTCA GTCGTGTTAC AGAAGCATTG TCTGCTAACT TCAACCACAA AAAAGATTTG 
ATTGAATTGC GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAAC TCAGGGATGC TGTAAAAGAA GCTGAGACCT GTGCTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAGAA ACACAGACAG AGCCCAGATA GTGGGAGGAC TCGGACCAAA 
CTGACAGTGG AAGAATTGAA GGCCTTTGTC CAACAACTTT TTAGTCTTCC GTGTGTCATC 
AGCCAAGCTC GGCAAGTAAA GAATCTGCTA GATGATGTGG AAGAGTTTCA TGAACGTGCT 
CAGGAGGCCA TGATGGATGA AACCCCAGAT TCTTCCAAAC TCCAGATGTT GATAGATATG 
GGCTCTAGTC TCTATGTGGA ACTCCCTGAA TTACCACGAC TGAAGCAAGA GCTACAACAG 
GCTCGGTGGT TGGACGAAGT AAGACTGACC TTATCAGATC CGCAACAAGT CACTTTGGAT 
GTCATGAAGA AGCTGATAGA CTCTGGGGTA GGGTTGGCAC CCCACCATGC TGTGGAGAAA 
GCAATGGCTG AACTACAGGA GCTCCTTACA GTCTCTGAAC GATGGGAAGA AAAGGCTAAG 
GTCTGCCTAC AGGCAAGACC GAGGCACAGT GTGGCAAGTT TAGAAAGCAT TGTGAATGAA 
GCCAAGAACA TTCCAGCCTT TCTACCCAAT GTGTTGTCCT TGAAAGAAGC CTTACAAAAG 
GCTCGAGAAT GGACCGCTAA AGTGGAAGCT ATTCAGAGTG GCAGCAATTA CGCTTATTTG 
GAGCAGCTTG AGAGCTTGTC TGCGAAAGGA CGCCCTATTC CTGTGCGTCT TGAAGCACTG 
CCGCAAGTGG AATCACAGGT AGCAGCAGCA CGGGCATGGA GAGAACGGAC TGGGCGGACG 
TTTCTTAAGA AGAATTCTAG CCATACATTG TTACAGGTGC TGAGCCCCCG GACCGACATT 
GGTGTATATG GGAGTGGCAA AAATAGGAGG AAAAAAGTAA AAGAACTAAT AGAAAAAGAA 
AAAGAAAAGG ATCTGGACCT GGAGCCTCTG AGTGATCTGG AGGAAGGATT GGAGGAAACC 
AGAGATACAG CCATGGTGGT GGCAGTTTTC AAAGAACGGG AGCAAAAAGA GATTGAAGCC 
ATGCATTCTC TCAGAGCAGC CAACCTAGCC AAGATGACAA TGGTGGACCG CATAGAAGAA 
GTAAAATTTT GCATTTGCCG CAAGACAGCC AGTGGGTTTA TGCTACAGTG TGAGCTCTGC 
AAAGACTGGT TCCATAACAG CTGTGTTCCT CTTCCTAAAT CAAGTTCCCA AAAAAAAGGA 
TCCAGCTGGC AAGCTAAAGA AGTAAAATTC CTTTGCCCTC TTTGTATGCG GTCTCGAAGG 
CCCAGGCTAG AGACTATTCT GTCACTCCTG GTATCCCTTC AGAAGTTGCC CGTACGGTTG 
CCTGAAGGAG AGGCCCTGCA GTGTTTGACA GAACGTGCTA TGAGTTGGCA AGATAGAGCG 
CGGCAGGCTC TAGCCACAGA TGAACTATCC TCTGCCCTGG CCAAACTATC TGTGTTGAGC 
CAGCGTATGG TGGAACAGGC GGCTCGAGAA AAAACTGAAA AGATCATCAG TGCAGAACTC 
CAAAAAGCAG CTGCCAATCC AGACTTACAG GGACACTTAC CTAGTTTCCA GCAGTCTGCT 
TTTAACCGGG TGGTGAGCAG TGTGTCATCT TCTCCTCGAC AAACAATGGA CTATGATGAT 
GAAGAAACAG ACTCTGATGA AGACATTCGA GAGACATATG GCTACGACAT GAAGGACACA 
GCCAGTGTGA AGTCCTCTAG TAGTCTTGAA CCCAATCTTT TTTGTGATGA AGAGATTCCC 
ATCAAATCCG AGGAGGTGGT GACCCACATG TGGACAGCAC CTTCATTTTG TGCAGAGCAT 
GCTTATTCTT CTGCTTCTAA GAGTTGTTCT CAAGGTTCTA GCACCCCAAG GAAACAACCT 
CGGAAGAGCC CTTTGGTGCC CCGAAGTTTG GAACCTCCAG TGCTGGAGTT GTCACCTGGA 
GCTAAGGCAC AACTGGAAGA ACTTATGATG GTTGGAGATC TCCTGGAAGT ATCTCTGGAC 
GAGACTCAAC ACATATGGCG GATTTTGCAG GCCACACACC CACCCTCTGA AGACAGATTC 
TTGCATATCA TGGAGGATGA CAGCATGGAA GAGAAACCAC TAAAAGTGAA AGGAAAGGAC 
TCTTCAGAGA AGAAACGGAA ACGGAAGCTA GAAAAGGTAG AGCAACTTTT TGGAGAAGGA 
AAACAGAAGT CCAAGGAGTT AAAGAAAATG GACAAACCTA GAAAGAAGAA ATTAAAATTA 
GGTGCAGACA AATCAAAGGA GCTGAATAAA CTGGCCAAGA AACTAGCAAA AGAAGAAGAG 
AGAAAGAAAA AGAAGGAGAA GGCTGCTGCA GCCAAAGTTG AACTTGTGAA AGAGAGCACT 
GAAAAGAAAA GAGAGAAAAA GGTGCTGGAC ATCCCCTCAA AGTATGACTG GTCAGGAGCA 
GAGGAGTCTG ATGATGAGAA TGCTGTGTGC GCAGCACAGA ACTGCCAAAG GCCCTGCAAG 
GACAAGGTAG ACTGGGTACA ATGTGATGGT GGCTGTGATG AGTGGTTTCA TCAAGTTTGT 
GTGGGTGTAT CTCCAGAAAT GGCTGAAAAT GAAGATTACA TCTGTATAAA CTGTGCAAAG 
AAGCAGGGGC CAGTTAGCCC AGGTCCAGCA CCACCTCCTT CCTTCATAAT GAGCTACAAA 
CTACCAATGG AGGATCTTAA AGAGACCAGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KDM5A ( NM_001042603.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036068.1 Homo sapiens lysine demethylase 5A (KDM5A), mRNA.

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CloneID	OHu11481
Clone ID Related Accession (Same CDS sequence)	NM_001042603.2 , NM_001042603.3
Accession Version	NM_001042603.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5073bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	lysine-specific demethylase 5A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU182136.1, DA211439.1, AB209999.1 and AC007406.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_001042603.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209999.1, SRR1803617.197173.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000399788.7/ ENSP00000382688.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGGCG TGGGGCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC AGAGTGCCCC 
GTCTTTGAGC CGAGTTGGGA GGAGTTCACA GATCCGCTCA GCTTTATCGG CCGCATCCGG 
CCTTTGGCGG AGAAAACCGG CATCTGCAAA ATTCGGCCGC CCAAGGACTG GCAGCCTCCA 
TTTGCCTGTG AAGTAAAAAG CTTTCGTTTC ACTCCAAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CCAGAGTGAG ATTGGATTTC TTGGATCAAC TAGCAAAATT TTGGGAACTT 
CAAGGATCTA CTCTGAAGAT CCCTGTGGTA GAGAGAAAAA TCCTGGATCT GTATGCTTTG 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATGGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GTCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CATTATGAAA GAATTCTCTA CCCATATGAG CTTTTCCAGT CTGGTGTGAG CCTTATGGGT 
GTGCAGATGC CTAATTTAGA TCTTAAAGAA AAAGTGGAGC CTGAGGTTCT CAGCACTGAT 
ACCCAAACTT CCCCAGAGCC AGGCACAAGG ATGAACATTC TGCCGAAGAG AACAAGACGT 
GTGAAGACTC AGTCAGAATC TGGAGATGTG AGTAGAAACA CGGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGGCCCAA GGTTGTGGGC TTGGCAATGG GAACAAAAGA TAAAGAAGAT 
GAGGTCACCC GAAGACGAAA AGTTACCAAC AGGTCAGACG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GCACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGTAT GTTTTGTGGT 
CGGGGAAACA ATGAAGATAA ATTGCTTTTG TGTGATGGAT GTGATGACAG CTATCATACA 
TTTTGTCTAA TTCCTCCACT ACCTGATGTG CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTCGCCGAGG AATGTAGCAA ACCTCGAGAA GCCTTTGGAT TTGAACAAGC TGTACGAGAG 
TATACACTTC AGAGCTTTGG AGAGATGGCA GATAATTTTA AGTCTGATTA TTTTAATATG 
CCAGTCCATA TGGTTCCCAC AGAACTAGTA GAAAAGGAAT TTTGGCGGCT GGTAAGCAGC 
ATTGAAGAAG ATGTTATTGT GGAATATGGA GCAGATATCT CCTCAAAAGA CTTTGGAAGT 
GGATTTCCGG TGAAGGATGG GCGGAGAAAG ATTCTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTC CTGGAACAGT CTGTTCTTGC ACATATTAAT 
GTGGACATCT CTGGTATGAA AGTGCCGTGG CTCTATGTGG GAATGTGCTT CTCTTCTTTT 
TGCTGGCACA TTGAGGATCA CTGGAGTTAT TCCATCAACT ACTTGCACTG GGGGGAGCCA 
AAGACATGGT ATGGTGTGCC ATCTCATGCT GCAGAGCAAC TGGAGGAGGT GATGAGAGAG 
CTGGCCCCCG AGTTATTTGA ATCCCAGCCT GATCTTCTGC ATCAGTTAGT TACCATCATG 
AACCCCAACG TGCTAATGGA GCATGGTGTG CCTGTGTACA GGACCAATCA GTGTGCTGGC 
GAGTTTGTTG TGACATTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG CTACAACTTT 
GCTGAAGCTG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA ATGTGTAAAT 
CATTACCGAC GCCTAAGGCG CCACTGTGTC TTTTCACACG AGGAACTAAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTCTGCAA AGAATTGACT 
CTCATGACTG AAGAAGAAAC ACGATTAAGA GAGTCTGTTG TACAGATGGG TGTCCTGATG 
TCAGAAGAAG AAGTGTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACCACATGTT TTCTCTCTGC TCTCACATGT TCCTGTAATC CTGAGCGGCT TGTATGTCTC 
TACCATCCAA CTGATCTGTG CCCCTGCCCC ATGCAGAAGA AATGTCTTAG ATATCGCTAC 
CCATTAGAAG ACCTCCCTTC TCTGCTATAT GGTGTAAAAG TCAGGGCACA GTCCTATGAC 
ACTTGGGTCA GTCGTGTTAC AGAAGCATTG TCTGCTAACT TCAACCACAA AAAAGATTTG 
ATTGAATTGC GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAAC TCAGGGATGC TGTAAAAGAA GCTGAGACCT GTGCTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAGAA ACACAGACAG AGCCCAGATA GTGGGAGGAC TCGGACCAAA 
CTGACAGTGG AAGAATTGAA GGCCTTTGTC CAACAACTTT TTAGTCTTCC GTGTGTCATC 
AGCCAAGCTC GGCAAGTAAA GAATCTGCTA GATGATGTGG AAGAGTTTCA TGAACGTGCT 
CAGGAGGCCA TGATGGATGA AACCCCAGAT TCTTCCAAAC TCCAGATGTT GATAGATATG 
GGCTCTAGTC TCTATGTGGA ACTCCCTGAA TTACCACGAC TGAAGCAAGA GCTACAACAG 
GCTCGGTGGT TGGACGAAGT AAGACTGACC TTATCAGATC CGCAACAAGT CACTTTGGAT 
GTCATGAAGA AGCTGATAGA CTCTGGGGTA GGGTTGGCAC CCCACCATGC TGTGGAGAAA 
GCAATGGCTG AACTACAGGA GCTCCTTACA GTCTCTGAAC GATGGGAAGA AAAGGCTAAG 
GTCTGCCTAC AGGCAAGACC GAGGCACAGT GTGGCAAGTT TAGAAAGCAT TGTGAATGAA 
GCCAAGAACA TTCCAGCCTT TCTACCCAAT GTGTTGTCCT TGAAAGAAGC CTTACAAAAG 
GCTCGAGAAT GGACCGCTAA AGTGGAAGCT ATTCAGAGTG GCAGCAATTA CGCTTATTTG 
GAGCAGCTTG AGAGCTTGTC TGCGAAAGGA CGCCCTATTC CTGTGCGTCT TGAAGCACTG 
CCGCAAGTGG AATCACAGGT AGCAGCAGCA CGGGCATGGA GAGAACGGAC TGGGCGGACG 
TTTCTTAAGA AGAATTCTAG CCATACATTG TTACAGGTGC TGAGCCCCCG GACCGACATT 
GGTGTATATG GGAGTGGCAA AAATAGGAGG AAAAAAGTAA AAGAACTAAT AGAAAAAGAA 
AAAGAAAAGG ATCTGGACCT GGAGCCTCTG AGTGATCTGG AGGAAGGATT GGAGGAAACC 
AGAGATACAG CCATGGTGGT GGCAGTTTTC AAAGAACGGG AGCAAAAAGA GATTGAAGCC 
ATGCATTCTC TCAGAGCAGC CAACCTAGCC AAGATGACAA TGGTGGACCG CATAGAAGAA 
GTAAAATTTT GCATTTGCCG CAAGACAGCC AGTGGGTTTA TGCTACAGTG TGAGCTCTGC 
AAAGACTGGT TCCATAACAG CTGTGTTCCT CTTCCTAAAT CAAGTTCCCA AAAAAAAGGA 
TCCAGCTGGC AAGCTAAAGA AGTAAAATTC CTTTGCCCTC TTTGTATGCG GTCTCGAAGG 
CCCAGGCTAG AGACTATTCT GTCACTCCTG GTATCCCTTC AGAAGTTGCC CGTACGGTTG 
CCTGAAGGAG AGGCCCTGCA GTGTTTGACA GAACGTGCTA TGAGTTGGCA AGATAGAGCG 
CGGCAGGCTC TAGCCACAGA TGAACTATCC TCTGCCCTGG CCAAACTATC TGTGTTGAGC 
CAGCGTATGG TGGAACAGGC GGCTCGAGAA AAAACTGAAA AGATCATCAG TGCAGAACTC 
CAAAAAGCAG CTGCCAATCC AGACTTACAG GGACACTTAC CTAGTTTCCA GCAGTCTGCT 
TTTAACCGGG TGGTGAGCAG TGTGTCATCT TCTCCTCGAC AAACAATGGA CTATGATGAT 
GAAGAAACAG ACTCTGATGA AGACATTCGA GAGACATATG GCTACGACAT GAAGGACACA 
GCCAGTGTGA AGTCCTCTAG TAGTCTTGAA CCCAATCTTT TTTGTGATGA AGAGATTCCC 
ATCAAATCCG AGGAGGTGGT GACCCACATG TGGACAGCAC CTTCATTTTG TGCAGAGCAT 
GCTTATTCTT CTGCTTCTAA GAGTTGTTCT CAAGGTTCTA GCACCCCAAG GAAACAACCT 
CGGAAGAGCC CTTTGGTGCC CCGAAGTTTG GAACCTCCAG TGCTGGAGTT GTCACCTGGA 
GCTAAGGCAC AACTGGAAGA ACTTATGATG GTTGGAGATC TCCTGGAAGT ATCTCTGGAC 
GAGACTCAAC ACATATGGCG GATTTTGCAG GCCACACACC CACCCTCTGA AGACAGATTC 
TTGCATATCA TGGAGGATGA CAGCATGGAA GAGAAACCAC TAAAAGTGAA AGGAAAGGAC 
TCTTCAGAGA AGAAACGGAA ACGGAAGCTA GAAAAGGTAG AGCAACTTTT TGGAGAAGGA 
AAACAGAAGT CCAAGGAGTT AAAGAAAATG GACAAACCTA GAAAGAAGAA ATTAAAATTA 
GGTGCAGACA AATCAAAGGA GCTGAATAAA CTGGCCAAGA AACTAGCAAA AGAAGAAGAG 
AGAAAGAAAA AGAAGGAGAA GGCTGCTGCA GCCAAAGTTG AACTTGTGAA AGAGAGCACT 
GAAAAGAAAA GAGAGAAAAA GGTGCTGGAC ATCCCCTCAA AGTATGACTG GTCAGGAGCA 
GAGGAGTCTG ATGATGAGAA TGCTGTGTGC GCAGCACAGA ACTGCCAAAG GCCCTGCAAG 
GACAAGGTAG ACTGGGTACA ATGTGATGGT GGCTGTGATG AGTGGTTTCA TCAAGTTTGT 
GTGGGTGTAT CTCCAGAAAT GGCTGAAAAT GAAGATTACA TCTGTATAAA CTGTGCAAAG 
AAGCAGGGGC CAGTTAGCCC AGGTCCAGCA CCACCTCCTT CCTTCATAAT GAGCTACAAA 
CTACCAATGG AGGATCTTAA AGAGACCAGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036068.1
CDS	230..5302
Translation	MAGVGPGGYAAEFVPPPECPVFEPSWEEFTDPLSFIGRIRPLAEKTGICKIRPPKDWQPPFACEVKSFRFTPRVQRLNELEAMTRVRLDFLDQLAKFWELQGSTLKIPVVERKILDLYALSKIVASKGGFEMVTKEKKWSKVGSRLGYLPGKGTGSLLKSHYERILYPYELFQSGVSLMGVQMPNLDLKEKVEPEVLSTDTQTSPEPGTRMNILPKRTRRVKTQSESGDVSRNTELKKLQIFGAGPKVVGLAMGTKDKEDEVTRRRKVTNRSDAFNMQMRQRKGTLSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCVAEECSKPREAFGFEQAVREYTLQSFGEMADNFKSDYFNMPVHMVPTELVEKEFWRLVSSIEEDVIVEYGADISSKDFGSGFPVKDGRRKILPEEEEYALSGWNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEFVVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCVNHYRRLRRHCVFSHEELIFKMAADPECLDVGLAAMVCKELTLMTEEETRLRESVVQMGVLMSEEEVFELVPDDERQCSACRTTCFLSALTCSCNPERLVCLYHPTDLCPCPMQKKCLRYRYPLEDLPSLLYGVKVRAQSYDTWVSRVTEALSANFNHKKDLIELRVMLEDAEDRKYPENDLFRKLRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLTVEELKAFVQQLFSLPCVISQARQVKNLLDDVEEFHERAQEAMMDETPDSSKLQMLIDMGSSLYVELPELPRLKQELQQARWLDEVRLTLSDPQQVTLDVMKKLIDSGVGLAPHHAVEKAMAELQELLTVSERWEEKAKVCLQARPRHSVASLESIVNEAKNIPAFLPNVLSLKEALQKAREWTAKVEAIQSGSNYAYLEQLESLSAKGRPIPVRLEALPQVESQVAAARAWRERTGRTFLKKNSSHTLLQVLSPRTDIGVYGSGKNRRKKVKELIEKEKEKDLDLEPLSDLEEGLEETRDTAMVVAVFKEREQKEIEAMHSLRAANLAKMTMVDRIEEVKFCICRKTASGFMLQCELCKDWFHNSCVPLPKSSSQKKGSSWQAKEVKFLCPLCMRSRRPRLETILSLLVSLQKLPVRLPEGEALQCLTERAMSWQDRARQALATDELSSALAKLSVLSQRMVEQAAREKTEKIISAELQKAAANPDLQGHLPSFQQSAFNRVVSSVSSSPRQTMDYDDEETDSDEDIRETYGYDMKDTASVKSSSSLEPNLFCDEEIPIKSEEVVTHMWTAPSFCAEHAYSSASKSCSQGSSTPRKQPRKSPLVPRSLEPPVLELSPGAKAQLEELMMVGDLLEVSLDETQHIWRILQATHPPSEDRFLHIMEDDSMEEKPLKVKGKDSSEKKRKRKLEKVEQLFGEGKQKSKELKKMDKPRKKKLKLGADKSKELNKLAKKLAKEEERKKKKEKAAAAKVELVKESTEKKREKKVLDIPSKYDWSGAEESDDENAVCAAQNCQRPCKDKVDWVQCDGGCDEWFHQVCVGVSPEMAENEDYICINCAKKQGPVSPGPAPPPSFIMSYKLPMEDLKETS

Target ORF information:

RefSeq Version	NM_001042603.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine demethylase 5A (KDM5A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042603.3

ORF Insert Sequence:

ATGGCGGGCG TGGGGCCGGG GGGCTACGCG GCGGAGTTCG TGCCACCGCC AGAGTGCCCC 
GTCTTTGAGC CGAGTTGGGA GGAGTTCACA GATCCGCTCA GCTTTATCGG CCGCATCCGG 
CCTTTGGCGG AGAAAACCGG CATCTGCAAA ATTCGGCCGC CCAAGGACTG GCAGCCTCCA 
TTTGCCTGTG AAGTAAAAAG CTTTCGTTTC ACTCCAAGAG TCCAGCGCCT GAATGAACTT 
GAGGCAATGA CCAGAGTGAG ATTGGATTTC TTGGATCAAC TAGCAAAATT TTGGGAACTT 
CAAGGATCTA CTCTGAAGAT CCCTGTGGTA GAGAGAAAAA TCCTGGATCT GTATGCTTTG 
AGCAAGATTG TTGCCAGCAA AGGAGGTTTT GAAATGGTCA CCAAAGAGAA GAAATGGTCT 
AAAGTGGGTA GTCGCTTGGG ATATCTGCCA GGAAAAGGAA CTGGGTCTCT TTTGAAGTCA 
CATTATGAAA GAATTCTCTA CCCATATGAG CTTTTCCAGT CTGGTGTGAG CCTTATGGGT 
GTGCAGATGC CTAATTTAGA TCTTAAAGAA AAAGTGGAGC CTGAGGTTCT CAGCACTGAT 
ACCCAAACTT CCCCAGAGCC AGGCACAAGG ATGAACATTC TGCCGAAGAG AACAAGACGT 
GTGAAGACTC AGTCAGAATC TGGAGATGTG AGTAGAAACA CGGAACTGAA GAAACTTCAG 
ATTTTTGGGG CTGGGCCCAA GGTTGTGGGC TTGGCAATGG GAACAAAAGA TAAAGAAGAT 
GAGGTCACCC GAAGACGAAA AGTTACCAAC AGGTCAGACG CATTTAACAT GCAAATGAGA 
CAACGGAAAG GCACTCTCTC TGTTAACTTT GTTGATCTCT ATGTTTGTAT GTTTTGTGGT 
CGGGGAAACA ATGAAGATAA ATTGCTTTTG TGTGATGGAT GTGATGACAG CTATCATACA 
TTTTGTCTAA TTCCTCCACT ACCTGATGTG CCCAAAGGAG ACTGGAGGTG TCCTAAATGT 
GTCGCCGAGG AATGTAGCAA ACCTCGAGAA GCCTTTGGAT TTGAACAAGC TGTACGAGAG 
TATACACTTC AGAGCTTTGG AGAGATGGCA GATAATTTTA AGTCTGATTA TTTTAATATG 
CCAGTCCATA TGGTTCCCAC AGAACTAGTA GAAAAGGAAT TTTGGCGGCT GGTAAGCAGC 
ATTGAAGAAG ATGTTATTGT GGAATATGGA GCAGATATCT CCTCAAAAGA CTTTGGAAGT 
GGATTTCCGG TGAAGGATGG GCGGAGAAAG ATTCTGCCAG AAGAAGAGGA ATATGCACTT 
TCTGGTTGGA ATTTGAATAA CATGCCTGTC CTGGAACAGT CTGTTCTTGC ACATATTAAT 
GTGGACATCT CTGGTATGAA AGTGCCGTGG CTCTATGTGG GAATGTGCTT CTCTTCTTTT 
TGCTGGCACA TTGAGGATCA CTGGAGTTAT TCCATCAACT ACTTGCACTG GGGGGAGCCA 
AAGACATGGT ATGGTGTGCC ATCTCATGCT GCAGAGCAAC TGGAGGAGGT GATGAGAGAG 
CTGGCCCCCG AGTTATTTGA ATCCCAGCCT GATCTTCTGC ATCAGTTAGT TACCATCATG 
AACCCCAACG TGCTAATGGA GCATGGTGTG CCTGTGTACA GGACCAATCA GTGTGCTGGC 
GAGTTTGTTG TGACATTTCC TCGTGCCTAT CACTCTGGAT TTAACCAGGG CTACAACTTT 
GCTGAAGCTG TGAACTTCTG TACTGCTGAC TGGTTGCCCA TTGGACGTCA ATGTGTAAAT 
CATTACCGAC GCCTAAGGCG CCACTGTGTC TTTTCACACG AGGAACTAAT TTTCAAGATG 
GCAGCAGATC CAGAATGCTT AGATGTGGGG CTGGCTGCCA TGGTCTGCAA AGAATTGACT 
CTCATGACTG AAGAAGAAAC ACGATTAAGA GAGTCTGTTG TACAGATGGG TGTCCTGATG 
TCAGAAGAAG AAGTGTTTGA ACTTGTTCCT GATGATGAGC GGCAGTGTTC AGCATGCAGA 
ACCACATGTT TTCTCTCTGC TCTCACATGT TCCTGTAATC CTGAGCGGCT TGTATGTCTC 
TACCATCCAA CTGATCTGTG CCCCTGCCCC ATGCAGAAGA AATGTCTTAG ATATCGCTAC 
CCATTAGAAG ACCTCCCTTC TCTGCTATAT GGTGTAAAAG TCAGGGCACA GTCCTATGAC 
ACTTGGGTCA GTCGTGTTAC AGAAGCATTG TCTGCTAACT TCAACCACAA AAAAGATTTG 
ATTGAATTGC GAGTAATGCT GGAAGATGCT GAGGATAGGA AATACCCAGA GAATGATCTC 
TTTCGAAAAC TCAGGGATGC TGTAAAAGAA GCTGAGACCT GTGCTTCTGT GGCTCAGCTG 
CTTCTGAGCA AAAAGCAGAA ACACAGACAG AGCCCAGATA GTGGGAGGAC TCGGACCAAA 
CTGACAGTGG AAGAATTGAA GGCCTTTGTC CAACAACTTT TTAGTCTTCC GTGTGTCATC 
AGCCAAGCTC GGCAAGTAAA GAATCTGCTA GATGATGTGG AAGAGTTTCA TGAACGTGCT 
CAGGAGGCCA TGATGGATGA AACCCCAGAT TCTTCCAAAC TCCAGATGTT GATAGATATG 
GGCTCTAGTC TCTATGTGGA ACTCCCTGAA TTACCACGAC TGAAGCAAGA GCTACAACAG 
GCTCGGTGGT TGGACGAAGT AAGACTGACC TTATCAGATC CGCAACAAGT CACTTTGGAT 
GTCATGAAGA AGCTGATAGA CTCTGGGGTA GGGTTGGCAC CCCACCATGC TGTGGAGAAA 
GCAATGGCTG AACTACAGGA GCTCCTTACA GTCTCTGAAC GATGGGAAGA AAAGGCTAAG 
GTCTGCCTAC AGGCAAGACC GAGGCACAGT GTGGCAAGTT TAGAAAGCAT TGTGAATGAA 
GCCAAGAACA TTCCAGCCTT TCTACCCAAT GTGTTGTCCT TGAAAGAAGC CTTACAAAAG 
GCTCGAGAAT GGACCGCTAA AGTGGAAGCT ATTCAGAGTG GCAGCAATTA CGCTTATTTG 
GAGCAGCTTG AGAGCTTGTC TGCGAAAGGA CGCCCTATTC CTGTGCGTCT TGAAGCACTG 
CCGCAAGTGG AATCACAGGT AGCAGCAGCA CGGGCATGGA GAGAACGGAC TGGGCGGACG 
TTTCTTAAGA AGAATTCTAG CCATACATTG TTACAGGTGC TGAGCCCCCG GACCGACATT 
GGTGTATATG GGAGTGGCAA AAATAGGAGG AAAAAAGTAA AAGAACTAAT AGAAAAAGAA 
AAAGAAAAGG ATCTGGACCT GGAGCCTCTG AGTGATCTGG AGGAAGGATT GGAGGAAACC 
AGAGATACAG CCATGGTGGT GGCAGTTTTC AAAGAACGGG AGCAAAAAGA GATTGAAGCC 
ATGCATTCTC TCAGAGCAGC CAACCTAGCC AAGATGACAA TGGTGGACCG CATAGAAGAA 
GTAAAATTTT GCATTTGCCG CAAGACAGCC AGTGGGTTTA TGCTACAGTG TGAGCTCTGC 
AAAGACTGGT TCCATAACAG CTGTGTTCCT CTTCCTAAAT CAAGTTCCCA AAAAAAAGGA 
TCCAGCTGGC AAGCTAAAGA AGTAAAATTC CTTTGCCCTC TTTGTATGCG GTCTCGAAGG 
CCCAGGCTAG AGACTATTCT GTCACTCCTG GTATCCCTTC AGAAGTTGCC CGTACGGTTG 
CCTGAAGGAG AGGCCCTGCA GTGTTTGACA GAACGTGCTA TGAGTTGGCA AGATAGAGCG 
CGGCAGGCTC TAGCCACAGA TGAACTATCC TCTGCCCTGG CCAAACTATC TGTGTTGAGC 
CAGCGTATGG TGGAACAGGC GGCTCGAGAA AAAACTGAAA AGATCATCAG TGCAGAACTC 
CAAAAAGCAG CTGCCAATCC AGACTTACAG GGACACTTAC CTAGTTTCCA GCAGTCTGCT 
TTTAACCGGG TGGTGAGCAG TGTGTCATCT TCTCCTCGAC AAACAATGGA CTATGATGAT 
GAAGAAACAG ACTCTGATGA AGACATTCGA GAGACATATG GCTACGACAT GAAGGACACA 
GCCAGTGTGA AGTCCTCTAG TAGTCTTGAA CCCAATCTTT TTTGTGATGA AGAGATTCCC 
ATCAAATCCG AGGAGGTGGT GACCCACATG TGGACAGCAC CTTCATTTTG TGCAGAGCAT 
GCTTATTCTT CTGCTTCTAA GAGTTGTTCT CAAGGTTCTA GCACCCCAAG GAAACAACCT 
CGGAAGAGCC CTTTGGTGCC CCGAAGTTTG GAACCTCCAG TGCTGGAGTT GTCACCTGGA 
GCTAAGGCAC AACTGGAAGA ACTTATGATG GTTGGAGATC TCCTGGAAGT ATCTCTGGAC 
GAGACTCAAC ACATATGGCG GATTTTGCAG GCCACACACC CACCCTCTGA AGACAGATTC 
TTGCATATCA TGGAGGATGA CAGCATGGAA GAGAAACCAC TAAAAGTGAA AGGAAAGGAC 
TCTTCAGAGA AGAAACGGAA ACGGAAGCTA GAAAAGGTAG AGCAACTTTT TGGAGAAGGA 
AAACAGAAGT CCAAGGAGTT AAAGAAAATG GACAAACCTA GAAAGAAGAA ATTAAAATTA 
GGTGCAGACA AATCAAAGGA GCTGAATAAA CTGGCCAAGA AACTAGCAAA AGAAGAAGAG 
AGAAAGAAAA AGAAGGAGAA GGCTGCTGCA GCCAAAGTTG AACTTGTGAA AGAGAGCACT 
GAAAAGAAAA GAGAGAAAAA GGTGCTGGAC ATCCCCTCAA AGTATGACTG GTCAGGAGCA 
GAGGAGTCTG ATGATGAGAA TGCTGTGTGC GCAGCACAGA ACTGCCAAAG GCCCTGCAAG 
GACAAGGTAG ACTGGGTACA ATGTGATGGT GGCTGTGATG AGTGGTTTCA TCAAGTTTGT 
GTGGGTGTAT CTCCAGAAAT GGCTGAAAAT GAAGATTACA TCTGTATAAA CTGTGCAAAG 
AAGCAGGGGC CAGTTAGCCC AGGTCCAGCA CCACCTCCTT CCTTCATAAT GAGCTACAAA 
CTACCAATGG AGGATCTTAA AGAGACCAGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dynamic site-specific recruitment of RBP2 by pocket protein p130 modulates H3K4 methylation on E2F-responsive promoters.
Nucleic acids research46(1)174-188(2018 Jan)
Zargar ZU,Kimidi MR,Tyagi S

Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie9972-80(2018 Jan)
Dai B,Huang H,Guan F,Zhu G,Xiao Z,Mao B,Su H,Hu Z

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KDM5A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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