RALA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RALA
Entrez Gene ID	5898
Full Name	RAS like proto-oncogene A
Synonyms	RAL
General protein information	Preferred Names RAS like proto-oncogene A Names ras-related protein Ral-A RALA Ras like proto-oncogene A RAS-like protein A Ras family small GTP binding protein RALA ras related GTP binding protein A v-ral simian leukemia viral oncogene homolog A (ras related)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p14.1
Summary	The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008].
Disorder MIM:	179550

mRNA and Protein(s)

mRNA	Protein	Name
NM_005402.3	NP_005393.2	ras-related protein Ral-A precursor
XM_006715762.2	XP_006715825.1	ras-related protein Ral-A isoform X1
NM_005402.4	NP_005393.2	ras-related protein Ral-A precursor
XM_011515466.1	XP_011513768.1	ras-related protein Ral-A isoform X1
XM_006715762.3	XP_006715825.1	ras-related protein Ral-A isoform X1
XM_011515467.1	XP_011513769.1	ras-related protein Ral-A isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RALA	XP_001140368.1
Bos taurus (cattle)	RALA	NP_001029816.1
Drosophila melanogaster (fruit fly)	Rala	NP_726882.1
Xenopus tropicalis (tropical clawed frog)	rala	NP_001015915.1
Homo sapiens (human)	RALA	NP_005393.2
Caenorhabditis elegans (roundworm)	ral-1	NP_001254866.1
Mus musculus (house mouse)	Rala	NP_062364.3
Rattus norvegicus (Norway rat)	Rala	NP_112355.1
Gallus gallus (chicken)	RALA	XP_004939621.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012108	XP_320421.3
	RALA	XP_001099131.1
Canis lupus familiaris (dog)	RALA	XP_533083.2
Danio rerio (zebrafish)	ralaa	NP_957312.1

Gene Ontology
Bibliography

Related articles in PubMed

RalGPS2 is involved in tunneling nanotubes formation in 5637 bladder cancer cells.
D'Aloia A, Berruti G, Costa B, Schiller C, Ambrosini R, Pastori V, Martegani E, Ceriani M
Experimental cell research362(2)349-361(2018 Jan)

Surface PD-L1,?E-cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis.
Jinesh GG, Manyam GC, Mmeje CO, Baggerly KA, Kamat AM
Scientific reports7(1)9602(2017 Aug)

Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C.
Ganapathy S, Fagman JB, Shen L, Yu T, Zhou X, Dai W, Makriyannis A, Chen C
Oncotarget7(51)84326-84337(2016 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that RalA is overactivated in medulloblastoma.
Title: RalA is overactivated in medulloblastoma.

This study identifies a novel regulatory crosstalk between Ral and Arf6 that controls Ral function in cells.
Title: Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.

results suggest that the small GTPase RalA plays an important role in promoting invagination and trafficking of caveolae, not by potentiating the association between Cav-1 and FilA but by stimulating PLD2-mediated generation of phosphatidic acid.
Title: Phosphatidic Acid Produced by RalA-activated PLD2 Stimulates Caveolae-mediated Endocytosis and Trafficking in Endothelial Cells.

Lowering the level of cellular FLNA caused an elevation in RalA activity and resulted in selective interference with the normal intracellular trafficking and signaling of the D2R and D3R, through GRK2 and beta-arrestins, respectively. Active RalA was found to interact with GRK2 to sequester it from D2R. Knockdown of FLNA or coexpression of active RalA prevented D3R from coupling with G protein.
Title: RalA employs GRK2 and ?-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.

Study shows the additional benefits of anti-RalA autoantibody as a potential serological biomarker for prostate cancer (PCa), particularly in patients with normal PSA, and further demonstrate the utility of biomarker combinations in the immunodiagnosis of PCa.
Title: Evaluation and characterization of anti-RalA autoantibody as a potential serum biomarker in human prostate cancer.

The following RALA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RALA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16884	NM_005402.4 Latest version!	Homo sapiens RAS like proto-oncogene A (RALA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu16884	XM_011515466.1 Latest version!	Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu16884	XM_006715762.3 Latest version!	Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu60177	XM_011515467.1 Latest version!	Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu16884	NM_005402.3	Homo sapiens RAS like proto-oncogene A (RALA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu16884	XM_006715762.2	Homo sapiens RALA Ras like proto-oncogene A (RALA), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RALA ( NM_005402.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005393.2 Homo sapiens RAS like proto-oncogene A (RALA), mRNA.

Price & Availability↑

CloneID	OHu16884
Clone ID Related Accession (Same CDS sequence)	NM_005402.3 , XM_006715762.2 , NM_005402.4 , XM_011515466.1 , XM_006715762.3
Accession Version	NM_005402.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	ras-related protein Ral-A precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC313757.1, BC039858.1 and BM930625.1. On Feb 25, 2011 this sequence version replaced NM_005402.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.261276.1, SRR1803612.213239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005393.2
CDS	311..931
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	NM_005402.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RAS like proto-oncogene A (RALA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005402.3

ORF Insert Sequence:

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RALA ( NM_005402.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005393.2 Homo sapiens RAS like proto-oncogene A (RALA), mRNA.

Price & Availability↑

CloneID	OHu16884
Clone ID Related Accession (Same CDS sequence)	NM_005402.3 , XM_006715762.2 , NM_005402.4 , XM_011515466.1 , XM_006715762.3
Accession Version	NM_005402.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	ras-related protein Ral-A precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC313757.1 and BC039858.1. On Nov 23, 2018 this sequence version replaced NM_005402.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.815446.1, SRR1803612.213239.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000005257.7/ ENSP00000005257.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005393.2
CDS	292..912
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	NM_005402.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RAS like proto-oncogene A (RALA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005402.4

ORF Insert Sequence:

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RALA ( XM_006715762.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715825.1 Homo sapiens RALA Ras like proto-oncogene A (RALA), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu16884
Clone ID Related Accession (Same CDS sequence)	NM_005402.3 , XM_006715762.2 , NM_005402.4 , XM_011515466.1 , XM_006715762.3
Accession Version	XM_006715762.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ras-related protein Ral-A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006715762.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715825.1
CDS	103..723
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	XM_006715762.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RALA Ras like proto-oncogene A (RALA), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715762.2

ORF Insert Sequence:

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RALA ( XM_011515466.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011513768.1 Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu16884
Clone ID Related Accession (Same CDS sequence)	NM_005402.3 , XM_006715762.2 , NM_005402.4 , XM_011515466.1 , XM_006715762.3
Accession Version	XM_011515466.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ras-related protein Ral-A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011513768.1
CDS	355..975
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	XM_011515466.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515466.1

ORF Insert Sequence:

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RALA ( XM_006715762.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715825.1 Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X2, mRNA.

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CloneID	OHu16884
Clone ID Related Accession (Same CDS sequence)	NM_005402.3 , XM_006715762.2 , NM_005402.4 , XM_011515466.1 , XM_006715762.3
Accession Version	XM_006715762.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ras-related protein Ral-A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006715762.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715825.1
CDS	133..753
Translation	MAANKPKGQNSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLEDKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERCCIL

Target ORF information:

RefSeq Version	XM_006715762.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715762.3

ORF Insert Sequence:

ATGGCTGCAA ATAAGCCCAA GGGTCAGAAT TCTTTGGCTT TACACAAAGT CATCATGGTG 
GGCAGTGGTG GCGTGGGCAA GTCAGCTCTG ACTCTACAGT TCATGTACGA TGAGTTTGTG 
GAGGACTATG AGCCTACCAA AGCAGACAGC TATCGGAAGA AGGTAGTGCT AGATGGGGAG 
GAAGTCCAGA TCGATATCTT AGATACAGCT GGGCAGGAGG ACTACGCTGC AATTAGAGAC 
AACTACTTCC GAAGTGGGGA GGGGTTCCTC TGTGTTTTCT CTATTACAGA AATGGAATCC 
TTTGCAGCTA CAGCTGACTT CAGGGAGCAG ATTTTAAGAG TAAAAGAAGA TGAGAATGTT 
CCATTTCTAC TGGTTGGTAA CAAATCAGAT TTAGAAGATA AAAGACAGGT TTCTGTAGAA 
GAGGCAAAAA ACAGAGCTGA GCAGTGGAAT GTTAACTACG TGGAAACATC TGCTAAAACA 
CGAGCTAATG TTGACAAGGT ATTTTTTGAT TTAATGAGAG AAATTCGAGC GAGAAAGATG 
GAAGACAGCA AAGAAAAGAA TGGAAAAAAG AAGAGGAAAA GTTTAGCCAA GAGAATCAGA 
GAAAGATGCT GCATTTTATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RALA ( XM_011515467.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011513769.1 Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X3, mRNA.

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CloneID	OHu60177
Clone ID Related Accession (Same CDS sequence)	XM_011515467.1
Accession Version	XM_011515467.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ras-related protein Ral-A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCACCC TCCTCTCAGC CCACGGACAG GAAGTCGCTC CCCAGCTGCC CCGCCCCGCT 
CCCCAGCGCC CCGGAAGTGA TCTGTGGCGG CTGCTGCAGA GCCGCCAGGA GGAGGGTGGA 
TCTCCCCAGA GCAAAGCGTC GGAGTCCTCC TCCTCCTTCT CCTCCTCCTC CTCCTCCTCC 
TCCAGCCGCC CAGGCTCCCC CGCCACCCGT CAGACTCCTC CTTCGACCGC TCCCGGCGCG 
GGGCCTTCCA GGCGACAAGG ACCGAGTACC CTCCGGCCGG AGCCACGCAG CCGCGGCTTC 
CGGAGCCCTC GGGGCGGCGG ACTGGCTCGC GGTGCAGGCT GTACTGGCAT GACACCAACA 
TCTGCTTGGC GAGTTGAGGC CTCAGGAAGT TTTTACTCAT GGAAGAAGGC GAAGGGTGAG 
CAGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011513769.1
CDS	535..963
Translation	MITLLSAHGQEVAPQLPRPAPQRPGSDLWRLLQSRQEEGGSPQSKASESSSSFSSSSSSSSSRPGSPATRQTPPSTAPGAGPSRRQGPSTLRPEPRSRGFRSPRGGGLARGAGCTGMTPTSAWRVEASGSFYSWKKAKGEQV

Target ORF information:

RefSeq Version	XM_011515467.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RAS like proto-oncogene A (RALA), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515467.1

ORF Insert Sequence:

ATGATCACCC TCCTCTCAGC CCACGGACAG GAAGTCGCTC CCCAGCTGCC CCGCCCCGCT 
CCCCAGCGCC CCGGAAGTGA TCTGTGGCGG CTGCTGCAGA GCCGCCAGGA GGAGGGTGGA 
TCTCCCCAGA GCAAAGCGTC GGAGTCCTCC TCCTCCTTCT CCTCCTCCTC CTCCTCCTCC 
TCCAGCCGCC CAGGCTCCCC CGCCACCCGT CAGACTCCTC CTTCGACCGC TCCCGGCGCG 
GGGCCTTCCA GGCGACAAGG ACCGAGTACC CTCCGGCCGG AGCCACGCAG CCGCGGCTTC 
CGGAGCCCTC GGGGCGGCGG ACTGGCTCGC GGTGCAGGCT GTACTGGCAT GACACCAACA 
TCTGCTTGGC GAGTTGAGGC CTCAGGAAGT TTTTACTCAT GGAAGAAGGC GAAGGGTGAG 
CAGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RalGPS2 is involved in tunneling nanotubes formation in 5637 bladder cancer cells.
Experimental cell research362(2)349-361(2018 Jan)
D'Aloia A,Berruti G,Costa B,Schiller C,Ambrosini R,Pastori V,Martegani E,Ceriani M

Surface PD-L1,?E-cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis.
Scientific reports7(1)9602(2017 Aug)
Jinesh GG,Manyam GC,Mmeje CO,Baggerly KA,Kamat AM

Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C.
Oncotarget7(51)84326-84337(2016 Dec)
Ganapathy S,Fagman JB,Shen L,Yu T,Zhou X,Dai W,Makriyannis A,Chen C

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RALA cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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