Gene Symbol | RAD21 |
Entrez Gene ID | 5885 |
Full Name | RAD21 cohesin complex component |
Synonyms | CDLS4,HR21,HRAD21,MCD1,NXP1,SCC1,hHR21 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Cornelia de Lange syndrome 4, 614701 (3) |