Gene Symbol | RAC2 |
Entrez Gene ID | 5880 |
Full Name | Rac family small GTPase 2 |
Synonyms | EN-7,Gx,HSPC022,p21-Rac2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]. |
Disorder MIM: | |
Disorder Html: | Neutrophil immunodeficiency syndrome, 608203 (3) |