RAB2A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAB2A
Entrez Gene ID	5862
Full Name	RAB2A, member RAS oncogene family
Synonyms	LHX,RAB2
General protein information	Preferred Names RAB2A, member RAS oncogene family Names ras-related protein Rab-2A RAB2, member RAS oncogene family small GTP binding protein RAB2A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q12.1-q12.2
Summary	The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Disorder MIM:	179509

mRNA and Protein(s)

mRNA	Protein	Name
NM_002865.2	NP_002856.1	ras-related protein Rab-2A isoform a
NM_001242644.1	NP_001229573.1	ras-related protein Rab-2A isoform b
NM_002865.3	NP_002856.1	ras-related protein Rab-2A isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	RAB2A	NP_002856.1
	RAB2A	XP_001089894.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005393	XP_556035.3
Xenopus tropicalis (tropical clawed frog)	rab2a	XP_002936157.1
Gallus gallus (chicken)	RAB2A	NP_990559.1
Arabidopsis thaliana (thale cress)	RABB1C	NP_193450.1
Pan troglodytes (chimpanzee)	RAB2A	NP_001233386.1
Caenorhabditis elegans (roundworm)	unc-108	NP_491233.1
Canis lupus familiaris (dog)	RAB2A	NP_001003318.1
Mus musculus (house mouse)	Rab2a	NP_067493.1
Rattus norvegicus (Norway rat)	Rab2a	NP_113906.1
Danio rerio (zebrafish)	rab2a	NP_958862.1
Drosophila melanogaster (fruit fly)	Rab2	NP_001260732.1
Arabidopsis thaliana (thale cress)	GB2	NP_195311.1
Oryza sativa (rice)	Os02g0586400	NP_001047267.1

Gene Ontology
Bibliography

Related articles in PubMed

Rab2 promotes autophagic and endocytic lysosomal degradation.
L?rincz P, T?th S, Benk? P, Lakatos Z, Boda A, Glatz G, Zobel M, Bisi S, Heged?s K, Tak?ts S, Scita G, Juh?sz G
The Journal of cell biology216(7)1937-1947(2017 Jul)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway.
Dey KK, Bharti R, Dey G, Pal I, Rajesh Y, Chavan S, Das S, Das CK, Jena BC, Halder P, Ray JG, Kulavi I, Mandal M
Cancer gene therapy23(11)382-391(2016 Nov)

RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.
Kajiho H, Kajiho Y, Frittoli E, Confalonieri S, Bertalot G, Viale G, Di Fiore PP, Oldani A, Garre M, Beznoussenko GV, Palamidessi A, Vecchi M, Chavrier P, Perez F, Scita G
EMBO reports17(7)1061-80(2016 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Identify Rab2 as a key factor for autophagic and endocytic cargo delivery to and degradation in lysosomes.
Title: Rab2 promotes autophagic and endocytic lysosomal degradation.

S100A7 affects cell motility and invasion by regulating the RAB2A-associated MAPK signaling cascades.
Title: S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway.

our data reveal that RAB2A is new critical membrane trafficking players in the regulation of mesenchymal properties of normal and tumorigenic cells and a critical determinant of an invasive, proteolytic mode of BC progression.
Title: RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.

This study demonstrated that RAB2A mutation showing the highest statistical significance in Autism and Schizophrenia.
Title: De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia.

RAB2A variance has effect on the structure and function of the PFC and related cognitive functions.
Title: RAB2A Polymorphism impacts prefrontal morphology, functional connectivity, and working memory.

The following RAB2A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAB2A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12874	NM_002865.3 Latest version!	Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12575	NM_001242644.1 Latest version!	Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu12874	NM_002865.2	Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAB2A ( NM_002865.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002856.1 Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12874
Clone ID Related Accession (Same CDS sequence)	NM_002865.2 , NM_002865.3
Accession Version	NM_002865.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 639bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-17
Organism	Homo sapiens(human)
Product	ras-related protein Rab-2A isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA648682.1, X12953.1, AC068389.10 and AW301641.1. On Jun 18, 2011 this sequence version replaced NM_002865.1. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.36313.1, SRR1803616.126943.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTACG CCTATCTCTT CAAGTACATC ATAATCGGCG ACACAGGTGT TGGTAAATCA 
TGCTTATTGC TACAGTTTAC AGACAAGAGG TTTCAGCCAG TGCATGACCT TACTATTGGT 
GTAGAGTTCG GTGCTCGAAT GATAACTATT GATGGGAAAC AGATAAAACT TCAGATATGG 
GATACGGCAG GGCAAGAATC CTTTCGTTCC ATCACAAGGT CGTATTACAG AGGTGCAGCA 
GGAGCTTTAC TAGTTTACGA TATTACACGG AGAGATACAT TCAACCACTT GACAACCTGG 
TTAGAAGATG CCCGCCAGCA TTCCAATTCC AACATGGTCA TTATGCTTAT TGGAAATAAA 
AGTGATTTAG AATCTAGAAG AGAAGTAAAA AAAGAAGAAG GTGAAGCTTT TGCACGAGAA 
CATGGACTCA TCTTCATGGA AACGTCTGCT AAGACTGCTT CCAATGTAGA AGAGGCATTT 
ATTAATACAG CAAAAGAAAT TTATGAAAAA ATTCAAGAAG GAGTCTTTGA CATTAATAAT 
GAGGCAAATG GCATTAAAAT TGGCCCTCAG CATGCTGCTA CCAATGCAAC ACATGCAGGC 
AATCAGGGAG GACAGCAGGC TGGGGGCGGC TGCTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002856.1
CDS	299..937
Translation	MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC

Target ORF information:

RefSeq Version	NM_002865.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002865.2

ORF Insert Sequence:

ATGGCGTACG CCTATCTCTT CAAGTACATC ATAATCGGCG ACACAGGTGT TGGTAAATCA 
TGCTTATTGC TACAGTTTAC AGACAAGAGG TTTCAGCCAG TGCATGACCT TACTATTGGT 
GTAGAGTTCG GTGCTCGAAT GATAACTATT GATGGGAAAC AGATAAAACT TCAGATATGG 
GATACGGCAG GGCAAGAATC CTTTCGTTCC ATCACAAGGT CGTATTACAG AGGTGCAGCA 
GGAGCTTTAC TAGTTTACGA TATTACACGG AGAGATACAT TCAACCACTT GACAACCTGG 
TTAGAAGATG CCCGCCAGCA TTCCAATTCC AACATGGTCA TTATGCTTAT TGGAAATAAA 
AGTGATTTAG AATCTAGAAG AGAAGTAAAA AAAGAAGAAG GTGAAGCTTT TGCACGAGAA 
CATGGACTCA TCTTCATGGA AACGTCTGCT AAGACTGCTT CCAATGTAGA AGAGGCATTT 
ATTAATACAG CAAAAGAAAT TTATGAAAAA ATTCAAGAAG GAGTCTTTGA CATTAATAAT 
GAGGCAAATG GCATTAAAAT TGGCCCTCAG CATGCTGCTA CCAATGCAAC ACATGCAGGC 
AATCAGGGAG GACAGCAGGC TGGGGGCGGC TGCTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAB2A ( NM_002865.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002856.1 Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12874
Clone ID Related Accession (Same CDS sequence)	NM_002865.2 , NM_002865.3
Accession Version	NM_002865.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 639bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	ras-related protein Rab-2A isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA648682.1, X12953.1, AC068389.10 and AW301641.1. On Nov 22, 2018 this sequence version replaced NM_002865.2. Transcript Variant: This variant (1) represents the predominant transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.36313.1, SRR1660803.21042.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000262646.12/ ENSP00000262646.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGTACG CCTATCTCTT CAAGTACATC ATAATCGGCG ACACAGGTGT TGGTAAATCA 
TGCTTATTGC TACAGTTTAC AGACAAGAGG TTTCAGCCAG TGCATGACCT TACTATTGGT 
GTAGAGTTCG GTGCTCGAAT GATAACTATT GATGGGAAAC AGATAAAACT TCAGATATGG 
GATACGGCAG GGCAAGAATC CTTTCGTTCC ATCACAAGGT CGTATTACAG AGGTGCAGCA 
GGAGCTTTAC TAGTTTACGA TATTACACGG AGAGATACAT TCAACCACTT GACAACCTGG 
TTAGAAGATG CCCGCCAGCA TTCCAATTCC AACATGGTCA TTATGCTTAT TGGAAATAAA 
AGTGATTTAG AATCTAGAAG AGAAGTAAAA AAAGAAGAAG GTGAAGCTTT TGCACGAGAA 
CATGGACTCA TCTTCATGGA AACGTCTGCT AAGACTGCTT CCAATGTAGA AGAGGCATTT 
ATTAATACAG CAAAAGAAAT TTATGAAAAA ATTCAAGAAG GAGTCTTTGA CATTAATAAT 
GAGGCAAATG GCATTAAAAT TGGCCCTCAG CATGCTGCTA CCAATGCAAC ACATGCAGGC 
AATCAGGGAG GACAGCAGGC TGGGGGCGGC TGCTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002856.1
CDS	222..860
Translation	MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC

Target ORF information:

RefSeq Version	NM_002865.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002865.3

ORF Insert Sequence:

ATGGCGTACG CCTATCTCTT CAAGTACATC ATAATCGGCG ACACAGGTGT TGGTAAATCA 
TGCTTATTGC TACAGTTTAC AGACAAGAGG TTTCAGCCAG TGCATGACCT TACTATTGGT 
GTAGAGTTCG GTGCTCGAAT GATAACTATT GATGGGAAAC AGATAAAACT TCAGATATGG 
GATACGGCAG GGCAAGAATC CTTTCGTTCC ATCACAAGGT CGTATTACAG AGGTGCAGCA 
GGAGCTTTAC TAGTTTACGA TATTACACGG AGAGATACAT TCAACCACTT GACAACCTGG 
TTAGAAGATG CCCGCCAGCA TTCCAATTCC AACATGGTCA TTATGCTTAT TGGAAATAAA 
AGTGATTTAG AATCTAGAAG AGAAGTAAAA AAAGAAGAAG GTGAAGCTTT TGCACGAGAA 
CATGGACTCA TCTTCATGGA AACGTCTGCT AAGACTGCTT CCAATGTAGA AGAGGCATTT 
ATTAATACAG CAAAAGAAAT TTATGAAAAA ATTCAAGAAG GAGTCTTTGA CATTAATAAT 
GAGGCAAATG GCATTAAAAT TGGCCCTCAG CATGCTGCTA CCAATGCAAC ACATGCAGGC 
AATCAGGGAG GACAGCAGGC TGGGGGCGGC TGCTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAB2A ( NM_001242644.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001229573.1 Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12575
Clone ID Related Accession (Same CDS sequence)	NM_001242644.1
Accession Version	NM_001242644.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	ras-related protein Rab-2A isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA648682.1, AK297576.1, AC068389.10 and AW301641.1. On Jun 19, 2011 this sequence version replaced XR_108913.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. This results in a shorter isoform (b) missing an internal protein segment compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.239583.1, SRR1803614.272327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTACG CCTATCTCTT CAAGTACATC ATAATCGGCG ACACAGGTGT AGAGTTCGGT 
GCTCGAATGA TAACTATTGA TGGGAAACAG ATAAAACTTC AGATATGGGA TACGGCAGGG 
CAAGAATCCT TTCGTTCCAT CACAAGGTCG TATTACAGAG GTGCAGCAGG AGCTTTACTA 
GTTTACGATA TTACACGGAG AGATACATTC AACCACTTGA CAACCTGGTT AGAAGATGCC 
CGCCAGCATT CCAATTCCAA CATGGTCATT ATGCTTATTG GAAATAAAAG TGATTTAGAA 
TCTAGAAGAG AAGTAAAAAA AGAAGAAGGT GAAGCTTTTG CACGAGAACA TGGACTCATC 
TTCATGGAAA CGTCTGCTAA GACTGCTTCC AATGTAGAAG AGGCATTTAT TAATACAGCA 
AAAGAAATTT ATGAAAAAAT TCAAGAAGGA GTCTTTGACA TTAATAATGA GGCAAATGGC 
ATTAAAATTG GCCCTCAGCA TGCTGCTACC AATGCAACAC ATGCAGGCAA TCAGGGAGGA 
CAGCAGGCTG GGGGCGGCTG CTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001229573.1
CDS	299..865
Translation	MAYAYLFKYIIIGDTGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC

Target ORF information:

RefSeq Version	NM_001242644.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RAB2A, member RAS oncogene family (RAB2A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001242644.1

ORF Insert Sequence:

ATGGCGTACG CCTATCTCTT CAAGTACATC ATAATCGGCG ACACAGGTGT AGAGTTCGGT 
GCTCGAATGA TAACTATTGA TGGGAAACAG ATAAAACTTC AGATATGGGA TACGGCAGGG 
CAAGAATCCT TTCGTTCCAT CACAAGGTCG TATTACAGAG GTGCAGCAGG AGCTTTACTA 
GTTTACGATA TTACACGGAG AGATACATTC AACCACTTGA CAACCTGGTT AGAAGATGCC 
CGCCAGCATT CCAATTCCAA CATGGTCATT ATGCTTATTG GAAATAAAAG TGATTTAGAA 
TCTAGAAGAG AAGTAAAAAA AGAAGAAGGT GAAGCTTTTG CACGAGAACA TGGACTCATC 
TTCATGGAAA CGTCTGCTAA GACTGCTTCC AATGTAGAAG AGGCATTTAT TAATACAGCA 
AAAGAAATTT ATGAAAAAAT TCAAGAAGGA GTCTTTGACA TTAATAATGA GGCAAATGGC 
ATTAAAATTG GCCCTCAGCA TGCTGCTACC AATGCAACAC ATGCAGGCAA TCAGGGAGGA 
CAGCAGGCTG GGGGCGGCTG CTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rab2 promotes autophagic and endocytic lysosomal degradation.
The Journal of cell biology216(7)1937-1947(2017 Jul)
L?rincz P,T?th S,Benk? P,Lakatos Z,Boda A,Glatz G,Zobel M,Bisi S,Heged?s K,Tak?ts S,Scita G,Juh?sz G

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway.
Cancer gene therapy23(11)382-391(2016 Nov)
Dey KK,Bharti R,Dey G,Pal I,Rajesh Y,Chavan S,Das S,Das CK,Jena BC,Halder P,Ray JG,Kulavi I,Mandal M

RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.
EMBO reports17(7)1061-80(2016 07)
Kajiho H,Kajiho Y,Frittoli E,Confalonieri S,Bertalot G,Viale G,Di Fiore PP,Oldani A,Garre M,Beznoussenko GV,Palamidessi A,Vecchi M,Chavrier P,Perez F,Scita G

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RAB2A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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