CACTIN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CACTIN
Entrez Gene ID	58509
Full Name	cactin, spliceosome C complex subunit
Synonyms	C19orf29,NY-REN-24,fSAPc
General protein information	Preferred Names cactin, spliceosome C complex subunit Names cactin NY REN 24 antigen functional spliceosome-associated protein c renal carcinoma antigen NY-REN-24
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_021231.1	NP_067054.1	cactin
NM_001080543.1	NP_001074012.1	cactin
XM_011528160.2	XP_011526462.1	cactin isoform X1
XM_011528161.2	XP_011526463.1	cactin isoform X2
NM_001080543.2	NP_001074012.1	cactin

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	cactin	NP_523422.3
Pan troglodytes (chimpanzee)	CACTIN	XP_001135512.2
	LOC721737	XP_002801071.1
Canis lupus familiaris (dog)	CACTIN	XP_542173.3
Mus musculus (house mouse)	Cactin	NP_081657.1
Homo sapiens (human)	CACTIN	NP_067054.1
Rattus norvegicus (Norway rat)	Cactin	NP_001074916.1
Gallus gallus (chicken)	CACTIN	XP_418192.3
Caenorhabditis elegans (roundworm)	cacn-1	NP_001254420.1
Xenopus tropicalis (tropical clawed frog)	cactin	XP_002942250.2
Danio rerio (zebrafish)	cactin	XP_005168489.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006542	XP_316580.4
Caenorhabditis elegans (roundworm)	cacn-1	NP_001254422.1
Arabidopsis thaliana (thale cress)	AT1G03910	NP_171887.1

Gene Ontology
Bibliography

Related articles in PubMed

Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.
Zanini IM, Soneson C, Lorenzi LE, Azzalin CM
Journal of cell science130(4)767-778(2017 02)

TRIM39 negatively regulates the NF?B-mediated signaling pathway through stabilization of Cactin.
Suzuki M, Watanabe M, Nakamaru Y, Takagi D, Takahashi H, Fukuda S, Hatakeyama S
Cellular and molecular life sciences : CMLS73(5)1085-101(2016 Mar)

Possible role of cortactin phosphorylation by protein kinase C? in actin-bundle formation at growth cone.
Yamada H, Kikuchi T, Masumoto T, Wei FY, Abe T, Takeda T, Nishiki T, Tomizawa K, Watanabe M, Matsui H, Takei K
Biology of the cell107(9)319-30(2015 Sep)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs.
Title: Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.

TRIM39 negatively regulates the NFkappaB signaling pathway possibly via stabilization of cactin.
Title: TRIM39 negatively regulates the NF?B-mediated signaling pathway through stabilization of Cactin.

results indicate that PKC-mediated cortactin phosphorylation might be implicated in the maintenance of growth cone
Title: Possible role of cortactin phosphorylation by protein kinase C? in actin-bundle formation at growth cone.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following CACTIN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CACTIN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03703	NM_001080543.2 Latest version!	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu03703	NM_021231.1 Latest version!	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu71006	XM_011528160.2 Latest version!	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu71007	XM_011528161.2 Latest version!	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu03703	NM_001080543.1	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CACTIN ( NM_021231.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_067054.1 Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03703
Clone ID Related Accession (Same CDS sequence)	NM_021231.1 , NM_001080543.1 , NM_001080543.2
Accession Version	NM_021231.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	cactin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN305928.1, BF196424.1, CO248922.1, AW027691.1, CF272634.1, AC005175.1 and BC019848.1. On Mar 9, 2007 this sequence version replaced XM_944935.2. Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AY917150.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGCTGC GTGAGCGCCA CCAGGACGTG 
CTGCGGCAGA AGCTGTACAA ACTGAAGCAG GAGCAGGGCG TGGAGAGCGA GCCGCTGTTC 
CCCATCCTCA AGCAGGAGCC CCAGTCCCCC AGCCGCAGCC TGGAGCCTGA GGACGCGGCG 
CCCACCCCGC CCGGGCCCTC CTCGGAGGGC GGCCCCGCGG AGGCCGAGGT GGACGGCGCG 
ACCCCGACAG AGGGCGACGG CGACGGGGAC GGTGAGGGCG AGGGCGAGGG CGAGGCGGTG 
CTCATGGAGG AGGACCTGAT CCAGCAGAGC CTGGACGACT ACGACGCCGG CAGGTACAGC 
CCGCGGCTGC TCACGGCGCA CGAGCTGCCA CTGGACGCGC ACGTGCTGGA ACCGGATGAG 
GACCTGCAGC GCCTGCAGCT CTCGCGCCAG CAGCTCCAGG TCACGGGAGA CGCCAGCGAG 
AGCGCCGAGG ACATCTTCTT CCGGCGGGCC AAGGAGGGCA TGGGCCAGGA CGAGGCGCAG 
TTCAGCGTGG AGATGCCACT CACCGGCAAG GCCTACCTGT GGGCCGACAA GTACCGGCCA 
CGCAAGCCGC GCTTCTTCAA CCGCGTGCAC ACGGGCTTCG AGTGGAACAA GTACAACCAG 
ACGCACTACG ACTTTGACAA CCCACCGCCC AAGATCGTGC AGGGATACAA GTTCAACATC 
TTCTACCCCG ACCTCATCGA CAAGCGCTCC ACGCCCGAGT ACTTCCTGGA GGCCTGCGCC 
GACAACAAGG ATTTCGCCAT CCTGCGCTTC CACGCGGGGC CGCCCTACGA GGACATCGCT 
TTCAAGATCG TCAACCGCGA GTGGGAATAC TCGCACCGCC ACGGCTTCCG CTGCCAGTTT 
GCCAACGGCA TCTTCCAGCT GTGGTTTCAC TTCAAGCGCT ACCGCTATCG GCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067054.1
CDS	54..2330
Translation	MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHELPLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

Target ORF information:

RefSeq Version	NM_021231.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021231.1

ORF Insert Sequence:

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGCTGC GTGAGCGCCA CCAGGACGTG 
CTGCGGCAGA AGCTGTACAA ACTGAAGCAG GAGCAGGGCG TGGAGAGCGA GCCGCTGTTC 
CCCATCCTCA AGCAGGAGCC CCAGTCCCCC AGCCGCAGCC TGGAGCCTGA GGACGCGGCG 
CCCACCCCGC CCGGGCCCTC CTCGGAGGGC GGCCCCGCGG AGGCCGAGGT GGACGGCGCG 
ACCCCGACAG AGGGCGACGG CGACGGGGAC GGTGAGGGCG AGGGCGAGGG CGAGGCGGTG 
CTCATGGAGG AGGACCTGAT CCAGCAGAGC CTGGACGACT ACGACGCCGG CAGGTACAGC 
CCGCGGCTGC TCACGGCGCA CGAGCTGCCA CTGGACGCGC ACGTGCTGGA ACCGGATGAG 
GACCTGCAGC GCCTGCAGCT CTCGCGCCAG CAGCTCCAGG TCACGGGAGA CGCCAGCGAG 
AGCGCCGAGG ACATCTTCTT CCGGCGGGCC AAGGAGGGCA TGGGCCAGGA CGAGGCGCAG 
TTCAGCGTGG AGATGCCACT CACCGGCAAG GCCTACCTGT GGGCCGACAA GTACCGGCCA 
CGCAAGCCGC GCTTCTTCAA CCGCGTGCAC ACGGGCTTCG AGTGGAACAA GTACAACCAG 
ACGCACTACG ACTTTGACAA CCCACCGCCC AAGATCGTGC AGGGATACAA GTTCAACATC 
TTCTACCCCG ACCTCATCGA CAAGCGCTCC ACGCCCGAGT ACTTCCTGGA GGCCTGCGCC 
GACAACAAGG ATTTCGCCAT CCTGCGCTTC CACGCGGGGC CGCCCTACGA GGACATCGCT 
TTCAAGATCG TCAACCGCGA GTGGGAATAC TCGCACCGCC ACGGCTTCCG CTGCCAGTTT 
GCCAACGGCA TCTTCCAGCT GTGGTTTCAC TTCAAGCGCT ACCGCTATCG GCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CACTIN ( NM_001080543.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001074012.1 Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03703
Clone ID Related Accession (Same CDS sequence)	NM_021231.1 , NM_001080543.1 , NM_001080543.2
Accession Version	NM_001080543.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cactin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN305928.1, BF196424.1, CO248922.1, AW027691.1, CF272634.1 and AC005175.1. On Jan 18, 2007 this sequence version replaced XM_933013.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AY917150.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGCTGC GTGAGCGCCA CCAGGACGTG 
CTGCGGCAGA AGCTGTACAA ACTGAAGCAG GAGCAGGGCG TGGAGAGCGA GCCGCTGTTC 
CCCATCCTCA AGCAGGAGCC CCAGTCCCCC AGCCGCAGCC TGGAGCCTGA GGACGCGGCG 
CCCACCCCGC CCGGGCCCTC CTCGGAGGGC GGCCCCGCGG AGGCCGAGGT GGACGGCGCG 
ACCCCGACAG AGGGCGACGG CGACGGGGAC GGTGAGGGCG AGGGCGAGGG CGAGGCGGTG 
CTCATGGAGG AGGACCTGAT CCAGCAGAGC CTGGACGACT ACGACGCCGG CAGGTACAGC 
CCGCGGCTGC TCACGGCGCA CGAGCTGCCA CTGGACGCGC ACGTGCTGGA ACCGGATGAG 
GACCTGCAGC GCCTGCAGCT CTCGCGCCAG CAGCTCCAGG TCACGGGAGA CGCCAGCGAG 
AGCGCCGAGG ACATCTTCTT CCGGCGGGCC AAGGAGGGCA TGGGCCAGGA CGAGGCGCAG 
TTCAGCGTGG AGATGCCACT CACCGGCAAG GCCTACCTGT GGGCCGACAA GTACCGGCCA 
CGCAAGCCGC GCTTCTTCAA CCGCGTGCAC ACGGGCTTCG AGTGGAACAA GTACAACCAG 
ACGCACTACG ACTTTGACAA CCCACCGCCC AAGATCGTGC AGGGATACAA GTTCAACATC 
TTCTACCCCG ACCTCATCGA CAAGCGCTCC ACGCCCGAGT ACTTCCTGGA GGCCTGCGCC 
GACAACAAGG ATTTCGCCAT CCTGCGCTTC CACGCGGGGC CGCCCTACGA GGACATCGCT 
TTCAAGATCG TCAACCGCGA GTGGGAATAC TCGCACCGCC ACGGCTTCCG CTGCCAGTTT 
GCCAACGGCA TCTTCCAGCT GTGGTTTCAC TTCAAGCGCT ACCGCTATCG GCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074012.1
CDS	54..2330
Translation	MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHELPLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

Target ORF information:

RefSeq Version	NM_001080543.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080543.1

ORF Insert Sequence:

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGCTGC GTGAGCGCCA CCAGGACGTG 
CTGCGGCAGA AGCTGTACAA ACTGAAGCAG GAGCAGGGCG TGGAGAGCGA GCCGCTGTTC 
CCCATCCTCA AGCAGGAGCC CCAGTCCCCC AGCCGCAGCC TGGAGCCTGA GGACGCGGCG 
CCCACCCCGC CCGGGCCCTC CTCGGAGGGC GGCCCCGCGG AGGCCGAGGT GGACGGCGCG 
ACCCCGACAG AGGGCGACGG CGACGGGGAC GGTGAGGGCG AGGGCGAGGG CGAGGCGGTG 
CTCATGGAGG AGGACCTGAT CCAGCAGAGC CTGGACGACT ACGACGCCGG CAGGTACAGC 
CCGCGGCTGC TCACGGCGCA CGAGCTGCCA CTGGACGCGC ACGTGCTGGA ACCGGATGAG 
GACCTGCAGC GCCTGCAGCT CTCGCGCCAG CAGCTCCAGG TCACGGGAGA CGCCAGCGAG 
AGCGCCGAGG ACATCTTCTT CCGGCGGGCC AAGGAGGGCA TGGGCCAGGA CGAGGCGCAG 
TTCAGCGTGG AGATGCCACT CACCGGCAAG GCCTACCTGT GGGCCGACAA GTACCGGCCA 
CGCAAGCCGC GCTTCTTCAA CCGCGTGCAC ACGGGCTTCG AGTGGAACAA GTACAACCAG 
ACGCACTACG ACTTTGACAA CCCACCGCCC AAGATCGTGC AGGGATACAA GTTCAACATC 
TTCTACCCCG ACCTCATCGA CAAGCGCTCC ACGCCCGAGT ACTTCCTGGA GGCCTGCGCC 
GACAACAAGG ATTTCGCCAT CCTGCGCTTC CACGCGGGGC CGCCCTACGA GGACATCGCT 
TTCAAGATCG TCAACCGCGA GTGGGAATAC TCGCACCGCC ACGGCTTCCG CTGCCAGTTT 
GCCAACGGCA TCTTCCAGCT GTGGTTTCAC TTCAAGCGCT ACCGCTATCG GCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CACTIN ( NM_001080543.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001074012.1 Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 1, mRNA.

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CloneID	OHu03703
Clone ID Related Accession (Same CDS sequence)	NM_021231.1 , NM_001080543.1 , NM_001080543.2
Accession Version	NM_001080543.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	cactin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN305928.1, BF196424.1, CO248922.1, AW027691.1, CF272634.1 and AC005175.1. On Nov 23, 2018 this sequence version replaced NM_001080543.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AY917150.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000429344.7/ ENSP00000415078.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGCTGC GTGAGCGCCA CCAGGACGTG 
CTGCGGCAGA AGCTGTACAA ACTGAAGCAG GAGCAGGGCG TGGAGAGCGA GCCGCTGTTC 
CCCATCCTCA AGCAGGAGCC CCAGTCCCCC AGCCGCAGCC TGGAGCCTGA GGACGCGGCG 
CCCACCCCGC CCGGGCCCTC CTCGGAGGGC GGCCCCGCGG AGGCCGAGGT GGACGGCGCG 
ACCCCGACAG AGGGCGACGG CGACGGGGAC GGTGAGGGCG AGGGCGAGGG CGAGGCGGTG 
CTCATGGAGG AGGACCTGAT CCAGCAGAGC CTGGACGACT ACGACGCCGG CAGGTACAGC 
CCGCGGCTGC TCACGGCGCA CGAGCTGCCA CTGGACGCGC ACGTGCTGGA ACCGGATGAG 
GACCTGCAGC GCCTGCAGCT CTCGCGCCAG CAGCTCCAGG TCACGGGAGA CGCCAGCGAG 
AGCGCCGAGG ACATCTTCTT CCGGCGGGCC AAGGAGGGCA TGGGCCAGGA CGAGGCGCAG 
TTCAGCGTGG AGATGCCACT CACCGGCAAG GCCTACCTGT GGGCCGACAA GTACCGGCCA 
CGCAAGCCGC GCTTCTTCAA CCGCGTGCAC ACGGGCTTCG AGTGGAACAA GTACAACCAG 
ACGCACTACG ACTTTGACAA CCCACCGCCC AAGATCGTGC AGGGATACAA GTTCAACATC 
TTCTACCCCG ACCTCATCGA CAAGCGCTCC ACGCCCGAGT ACTTCCTGGA GGCCTGCGCC 
GACAACAAGG ATTTCGCCAT CCTGCGCTTC CACGCGGGGC CGCCCTACGA GGACATCGCT 
TTCAAGATCG TCAACCGCGA GTGGGAATAC TCGCACCGCC ACGGCTTCCG CTGCCAGTTT 
GCCAACGGCA TCTTCCAGCT GTGGTTTCAC TTCAAGCGCT ACCGCTATCG GCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074012.1
CDS	29..2305
Translation	MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLYKLKQEQGVESEPLFPILKQEPQSPSRSLEPEDAAPTPPGPSSEGGPAEAEVDGATPTEGDGDGDGEGEGEGEAVLMEEDLIQQSLDDYDAGRYSPRLLTAHELPLDAHVLEPDEDLQRLQLSRQQLQVTGDASESAEDIFFRRAKEGMGQDEAQFSVEMPLTGKAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIDKRSTPEYFLEACADNKDFAILRFHAGPPYEDIAFKIVNREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

Target ORF information:

RefSeq Version	NM_001080543.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080543.2

ORF Insert Sequence:

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGCTGC GTGAGCGCCA CCAGGACGTG 
CTGCGGCAGA AGCTGTACAA ACTGAAGCAG GAGCAGGGCG TGGAGAGCGA GCCGCTGTTC 
CCCATCCTCA AGCAGGAGCC CCAGTCCCCC AGCCGCAGCC TGGAGCCTGA GGACGCGGCG 
CCCACCCCGC CCGGGCCCTC CTCGGAGGGC GGCCCCGCGG AGGCCGAGGT GGACGGCGCG 
ACCCCGACAG AGGGCGACGG CGACGGGGAC GGTGAGGGCG AGGGCGAGGG CGAGGCGGTG 
CTCATGGAGG AGGACCTGAT CCAGCAGAGC CTGGACGACT ACGACGCCGG CAGGTACAGC 
CCGCGGCTGC TCACGGCGCA CGAGCTGCCA CTGGACGCGC ACGTGCTGGA ACCGGATGAG 
GACCTGCAGC GCCTGCAGCT CTCGCGCCAG CAGCTCCAGG TCACGGGAGA CGCCAGCGAG 
AGCGCCGAGG ACATCTTCTT CCGGCGGGCC AAGGAGGGCA TGGGCCAGGA CGAGGCGCAG 
TTCAGCGTGG AGATGCCACT CACCGGCAAG GCCTACCTGT GGGCCGACAA GTACCGGCCA 
CGCAAGCCGC GCTTCTTCAA CCGCGTGCAC ACGGGCTTCG AGTGGAACAA GTACAACCAG 
ACGCACTACG ACTTTGACAA CCCACCGCCC AAGATCGTGC AGGGATACAA GTTCAACATC 
TTCTACCCCG ACCTCATCGA CAAGCGCTCC ACGCCCGAGT ACTTCCTGGA GGCCTGCGCC 
GACAACAAGG ATTTCGCCAT CCTGCGCTTC CACGCGGGGC CGCCCTACGA GGACATCGCT 
TTCAAGATCG TCAACCGCGA GTGGGAATAC TCGCACCGCC ACGGCTTCCG CTGCCAGTTT 
GCCAACGGCA TCTTCCAGCT GTGGTTTCAC TTCAAGCGCT ACCGCTATCG GCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CACTIN ( XM_011528160.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526462.1 Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant X1, mRNA.

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CloneID	OHu71006
Clone ID Related Accession (Same CDS sequence)	XM_011528160.2
Accession Version	XM_011528160.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1359bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cactin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011528160.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526462.1
CDS	49..1407
Translation	MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARAR

Target ORF information:

RefSeq Version	XM_011528160.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528160.2

ORF Insert Sequence:

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGGTGAGCGC CGCGAGGGGG TCAACGCCTC CGTCAGCTCT 
GATGTGCAGT CGGTGTTCAA GGGGAAGACA TACAACCAGC TGCAGGTCAT CTTCCAGGGC 
ATCGAGGGCA AAATCCGCGC TGGTGGCCCC AACCTGGACA TGGGCTACTG GGAGAGCCTC 
CTGCAGCAGC TTCGTGCCCA CATGGCACGG GCCCGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CACTIN ( XM_011528161.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526463.1 Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu71007
Clone ID Related Accession (Same CDS sequence)	XM_011528161.2
Accession Version	XM_011528161.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1248bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cactin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011528161.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGTGGAGCTT TGTGTTCCCC GGAGGTGGAG TTCACTCAGC 
CATCCTGTCC CTCCAGTGGT CTCCTCCGTG GGGCACATTC TCCCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526463.1
CDS	49..1296
Translation	MGRDTRSRSRSAGRRGRRRQSQSGSRSRSRSHGRRNRRRREDEGRRRRRRRSRERRSDSEEERWQRSGMRSRSPPRPKWHSRDGSSQSDSGEEQSRGQWARRRRRARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEELMKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGISHLEEKELKERNKRIQEDNRLELQKVKQLRLEREREKAMREQELEMLQREKEAEHFKTWEEQEDNFHLQQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNADFWRDMTTITEDEISKLRKLEASGKGPVELCVPRRWSSLSHPVPPVVSSVGHILP

Target ORF information:

RefSeq Version	XM_011528161.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cactin, spliceosome C complex subunit (CACTIN), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528161.2

ORF Insert Sequence:

ATGGGTCGGG ACACACGCTC GCGCTCGCGG TCCGCGGGTC GCCGGGGCCG AAGGCGGCAG 
AGTCAGAGCG GGAGCCGAAG TCGGAGCAGG AGCCATGGGC GGCGAAACCG ACGGCGCCGG 
GAGGACGAGG GACGGCGCAG ACGGAGGCGG CGGAGCCGGG AGCGCAGGTC AGATTCAGAG 
GAAGAGCGGT GGCAGCGCTC AGGGATGCGA AGCCGGAGCC CCCCGCGGCC CAAGTGGCAC 
TCAAGAGATG GGTCCTCTCA GTCGGACTCA GGAGAGGAGC AGTCACGGGG CCAGTGGGCT 
CGCCGGCGAC GGCGCGCACG CTCGTGGTCT CCTAGCTCCT CAGCATCCAG CTCCGCGTCT 
CCAGGGCGAT CCCAGAGCCC CCGGGCGGCC GCGGCTGCCC TGAGCCAGCA GCAGAGCCTG 
CAGGAGCGGC TGCGGCTGCG GGAGGAGCGG AAGCAGCAGG AGGAGCTGAT GAAGGCCTTC 
GAGACGCCCG AGGAGAAGCG CGCACGGCGG CTGGCCAAGA AGGAGGCCAA GGAGCGCAAG 
AAGCGGGAGA AGATGGGCTG GGGTGAGGAG TACATGGGCT ACACCAACAC CGACAACCCC 
TTCGGAGACA ACAACCTGCT GGGCACCTTC ATCTGGAATA AGGCCCTGGA GAAGAAGGGG 
ATCAGCCACC TGGAGGAGAA GGAGCTGAAG GAGCGGAACA AGAGGATCCA GGAGGACAAC 
CGGCTGGAGC TGCAGAAGGT GAAGCAGCTG CGGCTGGAGC GGGAGCGGGA GAAGGCCATG 
CGCGAGCAGG AGCTGGAGAT GCTGCAGCGC GAGAAGGAGG CAGAGCACTT CAAGACATGG 
GAGGAGCAGG AGGACAACTT CCACCTCCAG CAGGCCAAGC TGCGTTCCAA GATCCGCATC 
CGGGACGGGC GGGCCAAGCC CATCGACCTG CTGGCCAAGT ACATCAGCGC TGAGGATGAC 
GATCTGGCCG TGGAGATGCA TGAGCCCTAC ACGTTCCTCA ACGGCCTCAC CGTGGCCGAC 
ATGGAGGACC TGCTGGAGGA TATCCAGGTC TACATGGAGC TGGAGCAGGG CAAGAACGCC 
GACTTCTGGC GGGACATGAC CACCATCACC GAGGACGAGA TCTCCAAGCT CCGCAAGCTG 
GAGGCCTCGG GCAAGGGGCC AGTGGAGCTT TGTGTTCCCC GGAGGTGGAG TTCACTCAGC 
CATCCTGTCC CTCCAGTGGT CTCCTCCGTG GGGCACATTC TCCCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion.
Journal of cell science130(4)767-778(2017 02)
Zanini IM,Soneson C,Lorenzi LE,Azzalin CM

TRIM39 negatively regulates the NF?B-mediated signaling pathway through stabilization of Cactin.
Cellular and molecular life sciences : CMLS73(5)1085-101(2016 Mar)
Suzuki M,Watanabe M,Nakamaru Y,Takagi D,Takahashi H,Fukuda S,Hatakeyama S

Possible role of cortactin phosphorylation by protein kinase C? in actin-bundle formation at growth cone.
Biology of the cell107(9)319-30(2015 Sep)
Yamada H,Kikuchi T,Masumoto T,Wei FY,Abe T,Takeda T,Nishiki T,Tomizawa K,Watanabe M,Matsui H,Takei K

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
PloS one7(12)e51954(2012)
Comuzzie AG,Cole SA,Laston SL,Voruganti VS,Haack K,Gibbs RA,Butte NF

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CACTIN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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