BBS2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BBS2
Entrez Gene ID	583
Full Name	Bardet-Biedl syndrome 2
Synonyms	BBS,RP74
General protein information	Preferred Names Bardet-Biedl syndrome 2 Names Bardet-Biedl syndrome 2 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q13
Summary	This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.[provided by RefSeq, Oct 2014].
Disorder MIM:	606151
Disorder Html:	Bardet-Biedl syndrome 2, 615981 (3); Retinitis pigmentosa 74, 616562 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_031885.4	NP_114091.3	Bardet-Biedl syndrome 2 protein
NM_031885.3	NP_114091.3	Bardet-Biedl syndrome 2 protein
XM_005256080.2	XP_005256137.1	Bardet-Biedl syndrome 2 protein isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	BBS2	XP_510980.2
	BBS2	XP_001091861.1
Rattus norvegicus (Norway rat)	Bbs2	NP_446070.1
Danio rerio (zebrafish)	bbs2	NP_690843.1
Homo sapiens (human)	BBS2	NP_114091.3
Bos taurus (cattle)	BBS2	NP_001033249.1
Mus musculus (house mouse)	Bbs2	NP_080392.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009637	XP_318670.4
Canis lupus familiaris (dog)	BBS2	XP_535296.3
Gallus gallus (chicken)	BBS2	NP_001012795.1
Caenorhabditis elegans (roundworm)	bbs-2	NP_501325.1
Xenopus tropicalis (tropical clawed frog)	LOC100493660	XP_004913584.1

Gene Ontology
Bibliography

Related articles in PubMed

Protein interaction perturbation profiling at amino-acid resolution.
Woodsmith J, Apelt L, Casado-Medrano V, ?zkan Z, Timmermann B, Stelzl U
Nature methods14(12)1213-1221(2017 Dec)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.
Barbelanne M, Hossain D, Chan DP, Per?nen J, Tsang WY
Human molecular genetics24(8)2185-200(2015 Apr)

Whole Exome Sequencing Identifies a Novel and a Recurrent Mutation in BBS2 Gene in a Family with Bardet-Biedl Syndrome.
Bee YM, Chawla M, Zhao Y
BioMed research international2015524754(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our study shows that BBS2 mutations can cause nonsyndromic retinitis pigmentosa and highlights yet another candidate for this genetically heterogeneous condition.
Title: Association between missense mutations in the BBS2 gene and nonsyndromic retinitis pigmentosa.

we report here, for the first time, in Indian population, a novel, different profile of mutations in BBS genes (BBS3, BBS9, BBS10 and BBS2) compared to worldwide (BBS1 and 10) reports.
Title: Mutation spectrum in BBS genes guided by homozygosity mapping in an Indian cohort.

A pair of heterozygous nonsense mutations in BBS2 gene was identified in the proband, one being novel and the other recurrent. The novel mutation, p.Y644X, resides in exon 16 and was also found in the heterozygous state in the mother
Title: Whole Exome Sequencing Identifies a Novel and a Recurrent Mutation in BBS2 Gene in a Family with Bardet-Biedl Syndrome.

Carrier frequency has been determined for two BBS2 mutations present in the Ashkenazi Jewish population.
Title: Carrier frequency of two BBS2 mutations in the Ashkenazi population.

Novel mutation (c.115+5G>A) in BBS2 found in Tunisian families with Bardet-Biedl syndrome.
Title: Clinical and genetic characterization of Bardet-Biedl syndrome in Tunisia: defining a strategy for molecular diagnosis.

The following BBS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BBS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26277	NM_031885.4 Latest version!	Homo sapiens Bardet-Biedl syndrome 2 (BBS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu49450	XM_005256080.2 Latest version!	Homo sapiens Bardet-Biedl syndrome 2 (BBS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu26277	NM_031885.3	Homo sapiens Bardet-Biedl syndrome 2 (BBS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BBS2 ( NM_031885.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_114091.3 Homo sapiens Bardet-Biedl syndrome 2 (BBS2), mRNA.

Price & Availability↑

CloneID	OHu26277
Clone ID Related Accession (Same CDS sequence)	NM_031885.4 , NM_031885.3
Accession Version	NM_031885.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	Bardet-Biedl syndrome 2 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA437930.1, AF342736.1, DB316257.1 and AC092140.4. On Nov 23, 2018 this sequence version replaced NM_031885.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK027635.1, SRR1803616.91829.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGCTGC CTGTGTTCAC CCTGAAACTG CGCCACAAAA TCAGCCCCCG AATGGTGGCC 
ATAGGGCGCT ACGACGGGAC TCACCCGTGC CTGGCGGCCG CCACCCAAAC GGGCAAGGTT 
TTTATTCATA ATCCTCATAC ACGGAACCAG CATGTCAGTG CATCCAGGGT CTTCCAGAGC 
CCCCTGGAAT CTGATGTTTC TCTTCTCAAC ATTAACCAGG CAGTCAGCTG TCTGACTGCA 
GGCGTATTGA ACCCTGAGCT TGGCTATGAT GCCCTTTTAG TGGGGACACA GACTAATCTT 
TTGGCTTATG ATGTCTACAA TAATTCGGAT TTGTTCTACA GAGAGGTAGC AGATGGGGCA 
AATGCAATTG TGCTGGGGAC ATTGGGAGAC ATTTCTTCCC CTCTTGCGAT TATTGGTGGC 
AATTGTGCTC TGCAAGGTTT CAATCATGAA GGAAGTGATC TCTTTTGGAC GGTTACTGGA 
GACAATGTTA ATTCCTTGGC CTTGTGTGAC TTTGATGGTG ATGGAAAGAA AGAGCTTCTT 
GTTGGATCTG AGGATTTTGA TATCCGAGTT TTTAAGGAAG ATGAGATTGT GGCAGAAATG 
ACAGAAACAG AGATAGTCAC CTCTCTTTGT CCCATGTATG GCAGTCGATT TGGTTATGCC 
CTTTCCAATG GCACAGTTGG AGTTTATGAC AAAACATCCC GATACTGGAG AATTAAATCG 
AAAAATCATG CCATGAGCAT TCATGCTTTT GACCTTAATT CTGATGGAGT GAATGAACTG 
ATAACTGGTT GGTCCAATGG GAAGGTTGAT GCTCGAAGTG ACCGAACTGG GGAGGTCATC 
TTTAAGGACA ATTTTTCTTC TGCAATTGCC GGTGTGGTAG AGGGAGATTA CCGGATGGAT 
GGCCACATAC AGTTAATCTG CTGCTCAGTG GATGGGGAAA TCCGGGGCTA CCTGCCTGGC 
ACGGCTGAGA TGAGGGGCAA CCTCATGGAC ACCAGTGCAG AGCAGGACCT GATCCGAGAG 
CTGAGTCAGA AGAAGCAGAA TCTGTTGCTG GAACTCCGTA ACTATGAGGA AAATGCCAAG 
GCTGAATTGG CCAGTCCACT GAACGAGGCT GATGGGCATC GGGGCATAAT CCCAGCCAAT 
ACCAGGCTCC ACACCACGCT CTCAGTCAGC CTGGGGAATG AGACCCAAAC TGCTCATACA 
GAATTACGCA TTTCCACTTC TAATGACACC ATCATCCGAG CAGTATTGAT TTTTGCAGAA 
GGAATTTTTA CAGGTGAAAG CCACGTGGTA CATCCCAGCA TTCACAACCT CTCCAGTTCC 
ATCTGCATCC CTATTGTGCC TCCCAAAGAT GTCCCTGTGG ATCTGCACTT GAAGGCATTC 
GTGGGTTACA GAAGCAGCAC CCAGTTTCAT GTATTTGAAT CGACAAGACA GCTCCCTCGA 
TTCTCCATGT ATGCGCTGAC CAGCCTGGAC CCTGCCAGTG AGCCAATCAG TTATGTTAAC 
TTTACCATTG CAGAACGGGC ACAGAGGGTT GTTGTATGGC TCGGTCAGAA CTTTCTGTTA 
CCAGAAGACA CTCACATTCA GAATGCTCCA TTTCAAGTGT GTTTCACATC TTTACGGAAT 
GGCGGCCACC TGCATATAAA AATAAAACTT AGTGGAGAGA TCACTATAAA TACTGATGAT 
ATTGATTTGG CTGGTGATAT CATCCAGTCA ATGGCATCAT TTTTTGCTAT TGAAGACCTT 
CAAGTAGAAG CGGATTTTCC TGTCTATTTT GAGGAATTAC GAAAGGTGCT AGTTAAGGTG 
GATGAATATC ATTCAGTGCA TCAGAAGCTC AGTGCTGATA TGGCTGATCA TTCTAATTTG 
ATCCGAAGTT TGCTGGTCGG AGCTGAGGAT GCTCGTCTGA TGAGGGACAT GAAAACAATG 
AAGAGTCGTT ATATGGAACT CTATGACCTT AATAGAGACT TGCTAAATGG ATATAAAATT 
CGCTGTAACA ATCACACAGA GCTGTTGGGA AACCTCAAAG CAGTAAATCA AGCAATTCAA 
AGAGCAGGTC GTCTGCGGGT TGGAAAACCA AAGAACCAGG TGATCACTGC TTGTCGGGAT 
GCAATTCGAA GCAATAACAT CAACACACTG TTCAAAATCA TGCGAGTGGG GACAGCTTCT 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114091.3
CDS	163..2328
Translation	MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQSPLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGANAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKSKNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMDGHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAEGIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPRFSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTASS

Target ORF information:

RefSeq Version	NM_031885.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Bardet-Biedl syndrome 2 (BBS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031885.4

ORF Insert Sequence:

ATGCTGCTGC CTGTGTTCAC CCTGAAACTG CGCCACAAAA TCAGCCCCCG AATGGTGGCC 
ATAGGGCGCT ACGACGGGAC TCACCCGTGC CTGGCGGCCG CCACCCAAAC GGGCAAGGTT 
TTTATTCATA ATCCTCATAC ACGGAACCAG CATGTCAGTG CATCCAGGGT CTTCCAGAGC 
CCCCTGGAAT CTGATGTTTC TCTTCTCAAC ATTAACCAGG CAGTCAGCTG TCTGACTGCA 
GGCGTATTGA ACCCTGAGCT TGGCTATGAT GCCCTTTTAG TGGGGACACA GACTAATCTT 
TTGGCTTATG ATGTCTACAA TAATTCGGAT TTGTTCTACA GAGAGGTAGC AGATGGGGCA 
AATGCAATTG TGCTGGGGAC ATTGGGAGAC ATTTCTTCCC CTCTTGCGAT TATTGGTGGC 
AATTGTGCTC TGCAAGGTTT CAATCATGAA GGAAGTGATC TCTTTTGGAC GGTTACTGGA 
GACAATGTTA ATTCCTTGGC CTTGTGTGAC TTTGATGGTG ATGGAAAGAA AGAGCTTCTT 
GTTGGATCTG AGGATTTTGA TATCCGAGTT TTTAAGGAAG ATGAGATTGT GGCAGAAATG 
ACAGAAACAG AGATAGTCAC CTCTCTTTGT CCCATGTATG GCAGTCGATT TGGTTATGCC 
CTTTCCAATG GCACAGTTGG AGTTTATGAC AAAACATCCC GATACTGGAG AATTAAATCG 
AAAAATCATG CCATGAGCAT TCATGCTTTT GACCTTAATT CTGATGGAGT GAATGAACTG 
ATAACTGGTT GGTCCAATGG GAAGGTTGAT GCTCGAAGTG ACCGAACTGG GGAGGTCATC 
TTTAAGGACA ATTTTTCTTC TGCAATTGCC GGTGTGGTAG AGGGAGATTA CCGGATGGAT 
GGCCACATAC AGTTAATCTG CTGCTCAGTG GATGGGGAAA TCCGGGGCTA CCTGCCTGGC 
ACGGCTGAGA TGAGGGGCAA CCTCATGGAC ACCAGTGCAG AGCAGGACCT GATCCGAGAG 
CTGAGTCAGA AGAAGCAGAA TCTGTTGCTG GAACTCCGTA ACTATGAGGA AAATGCCAAG 
GCTGAATTGG CCAGTCCACT GAACGAGGCT GATGGGCATC GGGGCATAAT CCCAGCCAAT 
ACCAGGCTCC ACACCACGCT CTCAGTCAGC CTGGGGAATG AGACCCAAAC TGCTCATACA 
GAATTACGCA TTTCCACTTC TAATGACACC ATCATCCGAG CAGTATTGAT TTTTGCAGAA 
GGAATTTTTA CAGGTGAAAG CCACGTGGTA CATCCCAGCA TTCACAACCT CTCCAGTTCC 
ATCTGCATCC CTATTGTGCC TCCCAAAGAT GTCCCTGTGG ATCTGCACTT GAAGGCATTC 
GTGGGTTACA GAAGCAGCAC CCAGTTTCAT GTATTTGAAT CGACAAGACA GCTCCCTCGA 
TTCTCCATGT ATGCGCTGAC CAGCCTGGAC CCTGCCAGTG AGCCAATCAG TTATGTTAAC 
TTTACCATTG CAGAACGGGC ACAGAGGGTT GTTGTATGGC TCGGTCAGAA CTTTCTGTTA 
CCAGAAGACA CTCACATTCA GAATGCTCCA TTTCAAGTGT GTTTCACATC TTTACGGAAT 
GGCGGCCACC TGCATATAAA AATAAAACTT AGTGGAGAGA TCACTATAAA TACTGATGAT 
ATTGATTTGG CTGGTGATAT CATCCAGTCA ATGGCATCAT TTTTTGCTAT TGAAGACCTT 
CAAGTAGAAG CGGATTTTCC TGTCTATTTT GAGGAATTAC GAAAGGTGCT AGTTAAGGTG 
GATGAATATC ATTCAGTGCA TCAGAAGCTC AGTGCTGATA TGGCTGATCA TTCTAATTTG 
ATCCGAAGTT TGCTGGTCGG AGCTGAGGAT GCTCGTCTGA TGAGGGACAT GAAAACAATG 
AAGAGTCGTT ATATGGAACT CTATGACCTT AATAGAGACT TGCTAAATGG ATATAAAATT 
CGCTGTAACA ATCACACAGA GCTGTTGGGA AACCTCAAAG CAGTAAATCA AGCAATTCAA 
AGAGCAGGTC GTCTGCGGGT TGGAAAACCA AAGAACCAGG TGATCACTGC TTGTCGGGAT 
GCAATTCGAA GCAATAACAT CAACACACTG TTCAAAATCA TGCGAGTGGG GACAGCTTCT 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BBS2 ( NM_031885.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_114091.3 Homo sapiens Bardet-Biedl syndrome 2 (BBS2), mRNA.

Price & Availability↑

CloneID	OHu26277
Clone ID Related Accession (Same CDS sequence)	NM_031885.4 , NM_031885.3
Accession Version	NM_031885.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	Bardet-Biedl syndrome 2 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA437930.1, AF342736.1 and DB316257.1. This sequence is a reference standard in the RefSeqGene project. On Jan 9, 2009 this sequence version replaced NM_031885.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.107811.1, SRR1803616.91829.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGCTGC CTGTGTTCAC CCTGAAACTG CGCCACAAAA TCAGCCCCCG AATGGTGGCC 
ATAGGGCGCT ACGACGGGAC TCACCCGTGC CTGGCGGCCG CCACCCAAAC GGGCAAGGTT 
TTTATTCATA ATCCTCATAC ACGGAACCAG CATGTCAGTG CATCCAGGGT CTTCCAGAGC 
CCCCTGGAAT CTGATGTTTC TCTTCTCAAC ATTAACCAGG CAGTCAGCTG TCTGACTGCA 
GGCGTATTGA ACCCTGAGCT TGGCTATGAT GCCCTTTTAG TGGGGACACA GACTAATCTT 
TTGGCTTATG ATGTCTACAA TAATTCGGAT TTGTTCTACA GAGAGGTAGC AGATGGGGCA 
AATGCAATTG TGCTGGGGAC ATTGGGAGAC ATTTCTTCCC CTCTTGCGAT TATTGGTGGC 
AATTGTGCTC TGCAAGGTTT CAATCATGAA GGAAGTGATC TCTTTTGGAC GGTTACTGGA 
GACAATGTTA ATTCCTTGGC CTTGTGTGAC TTTGATGGTG ATGGAAAGAA AGAGCTTCTT 
GTTGGATCTG AGGATTTTGA TATCCGAGTT TTTAAGGAAG ATGAGATTGT GGCAGAAATG 
ACAGAAACAG AGATAGTCAC CTCTCTTTGT CCCATGTATG GCAGTCGATT TGGTTATGCC 
CTTTCCAATG GCACAGTTGG AGTTTATGAC AAAACATCCC GATACTGGAG AATTAAATCG 
AAAAATCATG CCATGAGCAT TCATGCTTTT GACCTTAATT CTGATGGAGT GAATGAACTG 
ATAACTGGTT GGTCCAATGG GAAGGTTGAT GCTCGAAGTG ACCGAACTGG GGAGGTCATC 
TTTAAGGACA ATTTTTCTTC TGCAATTGCC GGTGTGGTAG AGGGAGATTA CCGGATGGAT 
GGCCACATAC AGTTAATCTG CTGCTCAGTG GATGGGGAAA TCCGGGGCTA CCTGCCTGGC 
ACGGCTGAGA TGAGGGGCAA CCTCATGGAC ACCAGTGCAG AGCAGGACCT GATCCGAGAG 
CTGAGTCAGA AGAAGCAGAA TCTGTTGCTG GAACTCCGTA ACTATGAGGA AAATGCCAAG 
GCTGAATTGG CCAGTCCACT GAACGAGGCT GATGGGCATC GGGGCATAAT CCCAGCCAAT 
ACCAGGCTCC ACACCACGCT CTCAGTCAGC CTGGGGAATG AGACCCAAAC TGCTCATACA 
GAATTACGCA TTTCCACTTC TAATGACACC ATCATCCGAG CAGTATTGAT TTTTGCAGAA 
GGAATTTTTA CAGGTGAAAG CCACGTGGTA CATCCCAGCA TTCACAACCT CTCCAGTTCC 
ATCTGCATCC CTATTGTGCC TCCCAAAGAT GTCCCTGTGG ATCTGCACTT GAAGGCATTC 
GTGGGTTACA GAAGCAGCAC CCAGTTTCAT GTATTTGAAT CGACAAGACA GCTCCCTCGA 
TTCTCCATGT ATGCGCTGAC CAGCCTGGAC CCTGCCAGTG AGCCAATCAG TTATGTTAAC 
TTTACCATTG CAGAACGGGC ACAGAGGGTT GTTGTATGGC TCGGTCAGAA CTTTCTGTTA 
CCAGAAGACA CTCACATTCA GAATGCTCCA TTTCAAGTGT GTTTCACATC TTTACGGAAT 
GGCGGCCACC TGCATATAAA AATAAAACTT AGTGGAGAGA TCACTATAAA TACTGATGAT 
ATTGATTTGG CTGGTGATAT CATCCAGTCA ATGGCATCAT TTTTTGCTAT TGAAGACCTT 
CAAGTAGAAG CGGATTTTCC TGTCTATTTT GAGGAATTAC GAAAGGTGCT AGTTAAGGTG 
GATGAATATC ATTCAGTGCA TCAGAAGCTC AGTGCTGATA TGGCTGATCA TTCTAATTTG 
ATCCGAAGTT TGCTGGTCGG AGCTGAGGAT GCTCGTCTGA TGAGGGACAT GAAAACAATG 
AAGAGTCGTT ATATGGAACT CTATGACCTT AATAGAGACT TGCTAAATGG ATATAAAATT 
CGCTGTAACA ATCACACAGA GCTGTTGGGA AACCTCAAAG CAGTAAATCA AGCAATTCAA 
AGAGCAGGTC GTCTGCGGGT TGGAAAACCA AAGAACCAGG TGATCACTGC TTGTCGGGAT 
GCAATTCGAA GCAATAACAT CAACACACTG TTCAAAATCA TGCGAGTGGG GACAGCTTCT 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114091.3
CDS	235..2400
Translation	MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQSPLESDVSLLNINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGANAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKSKNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMDGHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAEGIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPRFSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTASS

Target ORF information:

RefSeq Version	NM_031885.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Bardet-Biedl syndrome 2 (BBS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031885.3

ORF Insert Sequence:

ATGCTGCTGC CTGTGTTCAC CCTGAAACTG CGCCACAAAA TCAGCCCCCG AATGGTGGCC 
ATAGGGCGCT ACGACGGGAC TCACCCGTGC CTGGCGGCCG CCACCCAAAC GGGCAAGGTT 
TTTATTCATA ATCCTCATAC ACGGAACCAG CATGTCAGTG CATCCAGGGT CTTCCAGAGC 
CCCCTGGAAT CTGATGTTTC TCTTCTCAAC ATTAACCAGG CAGTCAGCTG TCTGACTGCA 
GGCGTATTGA ACCCTGAGCT TGGCTATGAT GCCCTTTTAG TGGGGACACA GACTAATCTT 
TTGGCTTATG ATGTCTACAA TAATTCGGAT TTGTTCTACA GAGAGGTAGC AGATGGGGCA 
AATGCAATTG TGCTGGGGAC ATTGGGAGAC ATTTCTTCCC CTCTTGCGAT TATTGGTGGC 
AATTGTGCTC TGCAAGGTTT CAATCATGAA GGAAGTGATC TCTTTTGGAC GGTTACTGGA 
GACAATGTTA ATTCCTTGGC CTTGTGTGAC TTTGATGGTG ATGGAAAGAA AGAGCTTCTT 
GTTGGATCTG AGGATTTTGA TATCCGAGTT TTTAAGGAAG ATGAGATTGT GGCAGAAATG 
ACAGAAACAG AGATAGTCAC CTCTCTTTGT CCCATGTATG GCAGTCGATT TGGTTATGCC 
CTTTCCAATG GCACAGTTGG AGTTTATGAC AAAACATCCC GATACTGGAG AATTAAATCG 
AAAAATCATG CCATGAGCAT TCATGCTTTT GACCTTAATT CTGATGGAGT GAATGAACTG 
ATAACTGGTT GGTCCAATGG GAAGGTTGAT GCTCGAAGTG ACCGAACTGG GGAGGTCATC 
TTTAAGGACA ATTTTTCTTC TGCAATTGCC GGTGTGGTAG AGGGAGATTA CCGGATGGAT 
GGCCACATAC AGTTAATCTG CTGCTCAGTG GATGGGGAAA TCCGGGGCTA CCTGCCTGGC 
ACGGCTGAGA TGAGGGGCAA CCTCATGGAC ACCAGTGCAG AGCAGGACCT GATCCGAGAG 
CTGAGTCAGA AGAAGCAGAA TCTGTTGCTG GAACTCCGTA ACTATGAGGA AAATGCCAAG 
GCTGAATTGG CCAGTCCACT GAACGAGGCT GATGGGCATC GGGGCATAAT CCCAGCCAAT 
ACCAGGCTCC ACACCACGCT CTCAGTCAGC CTGGGGAATG AGACCCAAAC TGCTCATACA 
GAATTACGCA TTTCCACTTC TAATGACACC ATCATCCGAG CAGTATTGAT TTTTGCAGAA 
GGAATTTTTA CAGGTGAAAG CCACGTGGTA CATCCCAGCA TTCACAACCT CTCCAGTTCC 
ATCTGCATCC CTATTGTGCC TCCCAAAGAT GTCCCTGTGG ATCTGCACTT GAAGGCATTC 
GTGGGTTACA GAAGCAGCAC CCAGTTTCAT GTATTTGAAT CGACAAGACA GCTCCCTCGA 
TTCTCCATGT ATGCGCTGAC CAGCCTGGAC CCTGCCAGTG AGCCAATCAG TTATGTTAAC 
TTTACCATTG CAGAACGGGC ACAGAGGGTT GTTGTATGGC TCGGTCAGAA CTTTCTGTTA 
CCAGAAGACA CTCACATTCA GAATGCTCCA TTTCAAGTGT GTTTCACATC TTTACGGAAT 
GGCGGCCACC TGCATATAAA AATAAAACTT AGTGGAGAGA TCACTATAAA TACTGATGAT 
ATTGATTTGG CTGGTGATAT CATCCAGTCA ATGGCATCAT TTTTTGCTAT TGAAGACCTT 
CAAGTAGAAG CGGATTTTCC TGTCTATTTT GAGGAATTAC GAAAGGTGCT AGTTAAGGTG 
GATGAATATC ATTCAGTGCA TCAGAAGCTC AGTGCTGATA TGGCTGATCA TTCTAATTTG 
ATCCGAAGTT TGCTGGTCGG AGCTGAGGAT GCTCGTCTGA TGAGGGACAT GAAAACAATG 
AAGAGTCGTT ATATGGAACT CTATGACCTT AATAGAGACT TGCTAAATGG ATATAAAATT 
CGCTGTAACA ATCACACAGA GCTGTTGGGA AACCTCAAAG CAGTAAATCA AGCAATTCAA 
AGAGCAGGTC GTCTGCGGGT TGGAAAACCA AAGAACCAGG TGATCACTGC TTGTCGGGAT 
GCAATTCGAA GCAATAACAT CAACACACTG TTCAAAATCA TGCGAGTGGG GACAGCTTCT 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BBS2 ( XM_005256080.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256137.1 Homo sapiens Bardet-Biedl syndrome 2 (BBS2), transcript variant X1, mRNA.

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CloneID	OHu49450
Clone ID Related Accession (Same CDS sequence)	XM_005256080.2
Accession Version	XM_005256080.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2166bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Bardet-Biedl syndrome 2 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005256080.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCTGC CTGTGTTCAC CCTGAAACTG CGCCACAAAA TCAGCCCCCG AATGGTGGCC 
ATAGGGCGCT ACGACGGGAC TCACCCGTGC CTGGCGGCCG CCACCCAAAC GGGCAAGGTT 
TTTATTCATA ATCCTCATAC ACGGAACCAG CATGTCAGTG CATCCAGGGT CTTCCAGAGC 
CCCCTGGAAT CTGATGTTTC TCTTCTCAGC ATTAACCAGG CAGTCAGCTG TCTGACTGCA 
GGCGTATTGA ACCCTGAGCT TGGCTATGAT GCCCTTTTAG TGGGGACACA GACTAATCTT 
TTGGCTTATG ATGTCTACAA TAATTCGGAT TTGTTCTACA GAGAGGTAGC AGATGGGGCA 
AATGCAATTG TGCTGGGGAC ATTGGGAGAC ATTTCTTCCC CTCTTGCGAT TATTGGTGGC 
AATTGTGCTC TGCAAGGTTT CAATCATGAA GGAAGTGATC TCTTTTGGAC GGTTACTGGA 
GACAATGTTA ATTCCTTGGC CTTGTGTGAC TTTGATGGTG ATGGAAAGAA AGAGCTTCTT 
GTTGGATCTG AGGATTTTGA TATCCGAGTT TTTAAGGAAG ATGAGATTGT GGCAGAAATG 
ACAGAAACAG AGATAGTCAC CTCTCTTTGT CCCATGTATG GCAGTCGATT TGGTTATGCC 
CTTTCCAATG GCACAGTTGG AGTTTATGAC AAAACATCCC GATACTGGAG AATTAAATCG 
AAAAATCATG CCATGAGCAT TCATGCTTTT GACCTTAATT CTGATGGAGT GAATGAACTG 
ATAACTGGTT GGTCCAATGG GAAGGTTGAT GCTCGAAGTG ACCGAACTGG GGAGGTCATC 
TTTAAGGACA ATTTTTCTTC TGCAATTGCC GGTGTGGTAG AGGGAGATTA CCGGATGGAT 
GGCCACATAC AGTTAATCTG CTGCTCAGTG GATGGGGAAA TCCGGGGCTA CCTGCCTGGC 
ACGGCTGAGA TGAGGGGCAA CCTCATGGAC ACCAGTGCAG AGCAGGACCT GATCCGAGAG 
CTGAGTCAGA AGAAGCAGAA TCTGTTGCTG GAACTCCGTA ACTATGAGGA AAATGCCAAG 
GCTGAATTGG CCAGTCCACT GAACGAGGCT GATGGGCATC GGGGCATAAT CCCAGCCAAT 
ACCAGGCTCC ACACCACGCT CTCAGTCAGC CTGGGGAATG AGACCCAAAC TGCTCATACA 
GAATTACGCA TTTCCACTTC TAATGACACC ATCATCCGAG CAGTATTGAT TTTTGCAGAA 
GGAATTTTTA CAGGTGAAAG CCACGTGGTA CATCCCAGCA TTCACAACCT CTCCAGTTCC 
ATCTGCATCC CTATTGTGCC TCCCAAAGAT GTCCCTGTGG ATCTGCACTT GAAGGCATTC 
GTGGGTTACA GAAGCAGCAC CCAGTTTCAT GTATTTGAAT CGACAAGACA GCTCCCTCGA 
TTCTCCATGT ATGCGCTGAC CAGCCTGGAC CCTGCCAGTG AGCCAATCAG TTATGTTAAC 
TTTACCATTG CAGAACGGGC ACAGAGGGTT GTTGTATGGC TCGGTCAGAA CTTTCTGTTA 
CCAGAAGACA CTCACATTCA GAATGCTCCA TTTCAAGTGT GTTTCACATC TTTACGGAAT 
GGCGGCCACC TGCATATAAA AATAAAACTT AGTGGAGAGA TCACTATAAA TACTGATGAT 
ATTGATTTGG CTGGTGATAT CATCCAGTCA ATGGCATCAT TTTTTGCTAT TGAAGACCTT 
CAAGTAGAAG CGGATTTTCC TGTCTATTTT GAGGAATTAC GAAAGGTGCT AGTTAAGGTG 
GATGAATATC ATTCAGTGCA TCAGAAGCTC AGTGCTGATA TGGCTGATCA TTCTAATTTG 
ATCCGAAGTT TGCTGGTCGG AGCTGAGGAT GCTCGTCTGA TGAGGGACAT GAAAACAATG 
AAGAGTCGTT ATATGGAACT CTATGACCTT AATAGAGACT TGCTAAATGG ATATAAAATT 
CGCTGTAACA ATCACACAGA GCTGTTGGGA AACCTCAAAG CAGTAAATCA AGCAATTCAA 
AGAGCAGGTC GTCTGCGGGT TGGAAAACCA AAGAACCAGG TGATCACTGC TTGTCGGGAT 
GCAATTCGAA GCAATAACAT CAACACACTG TTCAAAATCA TGCGAGTGGG GACAGCTTCT 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256137.1
CDS	234..2399
Translation	MLLPVFTLKLRHKISPRMVAIGRYDGTHPCLAAATQTGKVFIHNPHTRNQHVSASRVFQSPLESDVSLLSINQAVSCLTAGVLNPELGYDALLVGTQTNLLAYDVYNNSDLFYREVADGANAIVLGTLGDISSPLAIIGGNCALQGFNHEGSDLFWTVTGDNVNSLALCDFDGDGKKELLVGSEDFDIRVFKEDEIVAEMTETEIVTSLCPMYGSRFGYALSNGTVGVYDKTSRYWRIKSKNHAMSIHAFDLNSDGVNELITGWSNGKVDARSDRTGEVIFKDNFSSAIAGVVEGDYRMDGHIQLICCSVDGEIRGYLPGTAEMRGNLMDTSAEQDLIRELSQKKQNLLLELRNYEENAKAELASPLNEADGHRGIIPANTRLHTTLSVSLGNETQTAHTELRISTSNDTIIRAVLIFAEGIFTGESHVVHPSIHNLSSSICIPIVPPKDVPVDLHLKAFVGYRSSTQFHVFESTRQLPRFSMYALTSLDPASEPISYVNFTIAERAQRVVVWLGQNFLLPEDTHIQNAPFQVCFTSLRNGGHLHIKIKLSGEITINTDDIDLAGDIIQSMASFFAIEDLQVEADFPVYFEELRKVLVKVDEYHSVHQKLSADMADHSNLIRSLLVGAEDARLMRDMKTMKSRYMELYDLNRDLLNGYKIRCNNHTELLGNLKAVNQAIQRAGRLRVGKPKNQVITACRDAIRSNNINTLFKIMRVGTASS

Target ORF information:

RefSeq Version	XM_005256080.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Bardet-Biedl syndrome 2 (BBS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256080.2

ORF Insert Sequence:

ATGCTGCTGC CTGTGTTCAC CCTGAAACTG CGCCACAAAA TCAGCCCCCG AATGGTGGCC 
ATAGGGCGCT ACGACGGGAC TCACCCGTGC CTGGCGGCCG CCACCCAAAC GGGCAAGGTT 
TTTATTCATA ATCCTCATAC ACGGAACCAG CATGTCAGTG CATCCAGGGT CTTCCAGAGC 
CCCCTGGAAT CTGATGTTTC TCTTCTCAGC ATTAACCAGG CAGTCAGCTG TCTGACTGCA 
GGCGTATTGA ACCCTGAGCT TGGCTATGAT GCCCTTTTAG TGGGGACACA GACTAATCTT 
TTGGCTTATG ATGTCTACAA TAATTCGGAT TTGTTCTACA GAGAGGTAGC AGATGGGGCA 
AATGCAATTG TGCTGGGGAC ATTGGGAGAC ATTTCTTCCC CTCTTGCGAT TATTGGTGGC 
AATTGTGCTC TGCAAGGTTT CAATCATGAA GGAAGTGATC TCTTTTGGAC GGTTACTGGA 
GACAATGTTA ATTCCTTGGC CTTGTGTGAC TTTGATGGTG ATGGAAAGAA AGAGCTTCTT 
GTTGGATCTG AGGATTTTGA TATCCGAGTT TTTAAGGAAG ATGAGATTGT GGCAGAAATG 
ACAGAAACAG AGATAGTCAC CTCTCTTTGT CCCATGTATG GCAGTCGATT TGGTTATGCC 
CTTTCCAATG GCACAGTTGG AGTTTATGAC AAAACATCCC GATACTGGAG AATTAAATCG 
AAAAATCATG CCATGAGCAT TCATGCTTTT GACCTTAATT CTGATGGAGT GAATGAACTG 
ATAACTGGTT GGTCCAATGG GAAGGTTGAT GCTCGAAGTG ACCGAACTGG GGAGGTCATC 
TTTAAGGACA ATTTTTCTTC TGCAATTGCC GGTGTGGTAG AGGGAGATTA CCGGATGGAT 
GGCCACATAC AGTTAATCTG CTGCTCAGTG GATGGGGAAA TCCGGGGCTA CCTGCCTGGC 
ACGGCTGAGA TGAGGGGCAA CCTCATGGAC ACCAGTGCAG AGCAGGACCT GATCCGAGAG 
CTGAGTCAGA AGAAGCAGAA TCTGTTGCTG GAACTCCGTA ACTATGAGGA AAATGCCAAG 
GCTGAATTGG CCAGTCCACT GAACGAGGCT GATGGGCATC GGGGCATAAT CCCAGCCAAT 
ACCAGGCTCC ACACCACGCT CTCAGTCAGC CTGGGGAATG AGACCCAAAC TGCTCATACA 
GAATTACGCA TTTCCACTTC TAATGACACC ATCATCCGAG CAGTATTGAT TTTTGCAGAA 
GGAATTTTTA CAGGTGAAAG CCACGTGGTA CATCCCAGCA TTCACAACCT CTCCAGTTCC 
ATCTGCATCC CTATTGTGCC TCCCAAAGAT GTCCCTGTGG ATCTGCACTT GAAGGCATTC 
GTGGGTTACA GAAGCAGCAC CCAGTTTCAT GTATTTGAAT CGACAAGACA GCTCCCTCGA 
TTCTCCATGT ATGCGCTGAC CAGCCTGGAC CCTGCCAGTG AGCCAATCAG TTATGTTAAC 
TTTACCATTG CAGAACGGGC ACAGAGGGTT GTTGTATGGC TCGGTCAGAA CTTTCTGTTA 
CCAGAAGACA CTCACATTCA GAATGCTCCA TTTCAAGTGT GTTTCACATC TTTACGGAAT 
GGCGGCCACC TGCATATAAA AATAAAACTT AGTGGAGAGA TCACTATAAA TACTGATGAT 
ATTGATTTGG CTGGTGATAT CATCCAGTCA ATGGCATCAT TTTTTGCTAT TGAAGACCTT 
CAAGTAGAAG CGGATTTTCC TGTCTATTTT GAGGAATTAC GAAAGGTGCT AGTTAAGGTG 
GATGAATATC ATTCAGTGCA TCAGAAGCTC AGTGCTGATA TGGCTGATCA TTCTAATTTG 
ATCCGAAGTT TGCTGGTCGG AGCTGAGGAT GCTCGTCTGA TGAGGGACAT GAAAACAATG 
AAGAGTCGTT ATATGGAACT CTATGACCTT AATAGAGACT TGCTAAATGG ATATAAAATT 
CGCTGTAACA ATCACACAGA GCTGTTGGGA AACCTCAAAG CAGTAAATCA AGCAATTCAA 
AGAGCAGGTC GTCTGCGGGT TGGAAAACCA AAGAACCAGG TGATCACTGC TTGTCGGGAT 
GCAATTCGAA GCAATAACAT CAACACACTG TTCAAAATCA TGCGAGTGGG GACAGCTTCT 
TCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Protein interaction perturbation profiling at amino-acid resolution.
Nature methods14(12)1213-1221(2017 Dec)
Woodsmith J,Apelt L,Casado-Medrano V,?zkan Z,Timmermann B,Stelzl U

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.
Human molecular genetics24(8)2185-200(2015 Apr)
Barbelanne M,Hossain D,Chan DP,Per?nen J,Tsang WY

Whole Exome Sequencing Identifies a Novel and a Recurrent Mutation in BBS2 Gene in a Family with Bardet-Biedl Syndrome.
BioMed research international2015524754(2015)
Bee YM,Chawla M,Zhao Y

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BBS2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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