PTPN14 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PTPN14
Entrez Gene ID	5784
Full Name	protein tyrosine phosphatase, non-receptor type 14
Synonyms	CATLPH,PEZ,PTP36
General protein information	Preferred Names protein tyrosine phosphatase, non-receptor type 14 Names tyrosine-protein phosphatase non-receptor type 14 cytoskeletal-associated protein tyrosine phosphatase protein-tyrosine phosphatase pez
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.3-q41
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010].
Disorder MIM:	603155
Disorder Html:	Choanal atresia and lymphedema, 613611 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024448759.1	XP_024304527.1	tyrosine-protein phosphatase non-receptor type 14 isoform X1
XM_017001941.1	XP_016857430.1	tyrosine-protein phosphatase non-receptor type 14 isoform X1
NM_005401.5	NP_005392.2	tyrosine-protein phosphatase non-receptor type 14
NM_005401.4	NP_005392.2	tyrosine-protein phosphatase non-receptor type 14

Pathways from BioSystems

Homologies

	PTPN14	XP_001106232.1
Homo sapiens (human)	PTPN14	NP_005392.2
Canis lupus familiaris (dog)	PTPN14	XP_849236.2
Bos taurus (cattle)	PTPN14	NP_001179428.1
Pan troglodytes (chimpanzee)	PTPN14	XP_001171366.1
Gallus gallus (chicken)	PTPN14	XP_419419.2
Mus musculus (house mouse)	Ptpn14	NP_033002.2
Xenopus tropicalis (tropical clawed frog)	ptpn14	XP_002934735.2

Gene Ontology
Bibliography

Related articles in PubMed

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD
Cancer cell32(4)460-473.e6(2017 Oct)

The PTPN14 Tumor Suppressor Is a Degradation Target of Human Papillomavirus E7.
Szalm?s A, Tomai? V, Basukala O, Massimi P, Mittal S, K?nya J, Banks L
Journal of virology91(7)(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

p53 deficiency promotes Yap signaling and that PTPN14 and TP53 mutations are mutually exclusive in human cancers.
Title: A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.

PTPN14 is classified as a potential tumor suppressor protein, and is very susceptible to HPV E7-induced proteasome-mediated degradation.
Title: The PTPN14 Tumor Suppressor Is a Degradation Target of Human Papillomavirus E7.

The Hippo signaling pathway was significantly associated with ER-negative breast cancer (pathway level P = 0.02). Gene-based analyses revealed that CDH1 was responsible for the pathway association (P < 0.01),corrected P = 0.02). rs142697907 in PTPN14 was associated with ER-positive breast cancer and rs2456773 in CDK1 with ER-negativity in case-only analysis after gene-level correction
Title: Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium.

study determined that high-risk E7 proteins target the proteolysis of the cellular protein tyrosine phosphatase PTPN14 and find that this activity is correlated with the retinoblastoma-independent transforming activity of E7
Title: High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.

PTPN14, a Pez mammalian homolog, is degraded by overexpressed Su(dx) or Su(dx) homologue WWP1 in mammalian cells.
Title: Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis.

The following PTPN14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTPN14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23231	NM_005401.5 Latest version!	Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu23231	XM_017001941.1 Latest version!	Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu23231	XM_024448759.1 Latest version!	Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
View Old Accession Versions >>
OHu23231	NM_005401.4	Homo sapiens protein tyrosine phosphatase, non-receptor type 14 (PTPN14), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PTPN14 ( NM_005401.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_005392.2 Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), mRNA.

Price & Availability↑

CloneID	OHu23231
Clone ID Related Accession (Same CDS sequence)	XM_024448759.1 , XM_017001941.1 , NM_005401.5 , NM_005401.4
Accession Version	NM_005401.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	tyrosine-protein phosphatase non-receptor type 14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA738908.1, AK291641.1, AL445305.11, AL603838.6 and AL929236.4. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_005401.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291641.1, X82676.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000366956.10/ ENSP00000355923.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005392.2
CDS	575..4138
Translation	MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI

Target ORF information:

RefSeq Version	NM_005401.5
Organism	Homo sapiens(human)
Definition	Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005401.5

ORF Insert Sequence:

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTPN14 ( NM_005401.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005392.2 Homo sapiens protein tyrosine phosphatase, non-receptor type 14 (PTPN14), mRNA.

Price & Availability↑

CloneID	OHu23231
Clone ID Related Accession (Same CDS sequence)	XM_024448759.1 , XM_017001941.1 , NM_005401.5 , NM_005401.4
Accession Version	NM_005401.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	tyrosine-protein phosphatase non-receptor type 14
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA738908.1, AK291641.1, AL445305.11, AL603838.6 and AL929236.4. This sequence is a reference standard in the RefSeqGene project. On Apr 20, 2010 this sequence version replaced NM_005401.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291641.1, X82676.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005392.2
CDS	654..4217
Translation	MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI

Target ORF information:

RefSeq Version	NM_005401.4
Organism	Homo sapiens(human)
Definition	Homo sapiens protein tyrosine phosphatase, non-receptor type 14 (PTPN14), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005401.4

ORF Insert Sequence:

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTPN14 ( XM_024448759.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304527.1 Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), transcript variant X1, mRNA.

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CloneID	OHu23231
Clone ID Related Accession (Same CDS sequence)	XM_024448759.1 , XM_017001941.1 , NM_005401.5 , NM_005401.4
Accession Version	XM_024448759.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tyrosine-protein phosphatase non-receptor type 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304527.1
CDS	804..4367
Translation	MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI

Target ORF information:

RefSeq Version	XM_024448759.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448759.1

ORF Insert Sequence:

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTPN14 ( XM_017001941.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857430.1 Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), transcript variant X2, mRNA.

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CloneID	OHu23231
Clone ID Related Accession (Same CDS sequence)	XM_024448759.1 , XM_017001941.1 , NM_005401.5 , NM_005401.4
Accession Version	XM_017001941.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	tyrosine-protein phosphatase non-receptor type 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857430.1
CDS	741..4304
Translation	MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRETHYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQYYLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAVLEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMGIFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATRHKFYKQNKICTEQSNSPPPIRRQPTWSRSSLPRQQPYILPPVHVQCGEHYSETHTSQDSIFHGNEEALYCNSHNSLDLNYLNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSNLSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNIINTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVYSNKLVSPSDQRNPKNNVVPSKPGASAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYVSGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMVRGMEAMTLKSLHLPMARRNTLREQGPPEEGSGSHEVPQLPQYHHKKTFSDATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVSNGALRQDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLTSVKERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQKRPLMLAALNGLSVARVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKKANGIFSTAALPENAERSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHPPIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQNSRLI

Target ORF information:

RefSeq Version	XM_017001941.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein tyrosine phosphatase non-receptor type 14 (PTPN14), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001941.1

ORF Insert Sequence:

ATGCCTTTTG GTCTGAAGCT CCGCCGGACA CGGCGCTACA ACGTCCTGAG CAAGAACTGC 
TTTGTCACAC GGATTCGCCT GCTGGACAGC AATGTTATCG AGTGCACGCT GTCGGTGGAA 
AGCACAGGGC AAGAATGCCT GGAGGCTGTG GCCCAGAGGC TGGAGCTGCG AGAGACGCAC 
TACTTTGGCC TTTGGTTTCT CAGCAAGAGC CAGCAAGCAC GATGGGTGGA GCTGGAGAAA 
CCTCTGAAGA AACATCTGGA CAAATTCGCT AATGAGCCTT TGCTTTTCTT TGGAGTCATG 
TTCTATGTGC CAAATGTGTC ATGGCTTCAG CAAGAGGCCA CAAGATATCA GTATTACCTG 
CAAGTCAAAA AAGATGTGCT TGAAGGGCGA TTACGATGTA CATTGGACCA GGTGATTCGG 
CTAGCCGGCC TAGCTGTGCA AGCTGATTTT GGAGACTATA ATCAGTTTGA TTCTCAAGAT 
TTCCTCAGAG AGTATGTGCT ATTTCCTATG GATTTGGCCC TGGAAGAGGC TGTTCTGGAG 
GAGCTGACCC AGAAGGTAGC CCAAGAACAC AAAGCCCACA GTGGAATCCT GCCAGCAGAA 
GCTGAACTGA TGTACATCAA TGAAGTTGAA CGTTTGGATG GATTTGGACA GGAAATCTTC 
CCTGTAAAGG ACAATCATGG AAACTGTGTA CACCTTGGCA TTTTCTTTAT GGGGATTTTC 
GTGAGGAACA GAATTGGAAG ACAAGCGGTA ATATACAGGT GGAATGACAT GGGGAATATC 
ACTCATAACA AGTCGACCAT TCTAGTGGAG CTCATCAACA AAGAAGAGAC TGCCCTCTTT 
CACACGGATG ATATCGAAAA TGCCAAGTAT ATTTCTCGGT TGTTTGCCAC ACGACACAAG 
TTTTACAAAC AAAACAAAAT CTGCACTGAA CAGTCAAATT CTCCACCCCC CATCAGACGC 
CAGCCCACCT GGAGCCGATC CTCTCTGCCC AGGCAGCAGC CGTACATCCT GCCTCCCGTT 
CACGTCCAGT GTGGTGAGCA CTACTCGGAA ACGCACACCT CGCAAGACAG CATTTTTCAT 
GGGAATGAAG AAGCCTTGTA TTGCAACTCT CACAACAGCC TGGACTTAAA TTATTTAAAT 
GGCACTGTCA CCAATGGCAG CGTGTGTAGC GTTCACAGCG TCAACTCCCT CAACTGCTCG 
CAAAGTTTCA TCCAGGCCTC CCCTGTATCC TCCAACCTCA GTATCCCTGG GAGTGACATC 
ATGCGGGCCG ACTACATCCC GAGCCACCGG CACAGCGCGA TCATCGTGCC CTCGTACAGG 
CCAACCCCCG ATTATGAGAC AGTCATGCGC CAGATGAAGA GGGGGATCCT GCATACAGAC 
AGCCAGAGCC AGTCTCTGAG AAACCTCAAC ATTATCAACA CCCATGCCTA CAACCAGCCA 
GAGGATCTGG TGTACAGCCA ACCGGAGATG CGGGAGAGGC ACCCCTACAC TGTCCCTTAT 
GGGCCACAGG GGGTCTACAG CAACAAACTT GTCAGTCCAT CTGACCAGAG GAACCCAAAG 
AATAATGTGG TACCAAGCAA GCCGGGGGCA AGCGCCATCT CGCACACGGT GAGCACCCCA 
GAGCTGGCCA ACATGCAGCT GCAGGGCAGC CATAACTACA GCACGGCCCA CATGCTTAAG 
AACTATCTCT TCAGGCCACC GCCCCCCTAC CCACGGCCAC GACCTGCCAC CAGCACCCCA 
GACCTGGCCA GCCACCGCCA CAAGTACGTC AGCGGCAGCA GCCCGGACCT GGTGACCCGG 
AAGGTGCAGC TCTCGGTGAA GACCTTCCAA GAGGACAGCT CTCCGGTGGT TCATCAGTCT 
CTCCAGGAGG TGAGCGAGCC CCTCACGGCC ACCAAGCACC ACGGCACTGT GAACAAGCGC 
CACAGCCTGG AGGTGATGAA CAGCATGGTG CGGGGCATGG AGGCCATGAC GCTCAAGTCG 
CTCCACCTCC CCATGGCTCG CCGCAACACG CTCCGGGAGC AGGGACCGCC CGAGGAGGGG 
TCAGGCAGCC ACGAGGTCCC CCAGCTCCCT CAGTATCACC ACAAGAAGAC CTTCTCTGAT 
GCCACTATGC TAATCCACAG CAGCGAGAGT GAGGAGGAGG AGGAGGAGGC TCCAGAATCG 
GTGCCCCAGA TCCCCATGCT CCGGGAGAAG ATGGAGTACA GTGCCCAGCT GCAGGCGGCC 
CTGGCCCGCA TCCCCAACAA GCCCCCGCCT GAGTACCCCG GTCCAAGGAA GAGTGTGAGC 
AATGGGGCTC TGAGGCAGGA CCAAGCCAGC CTTCCTCCCG CCATGGCCAG AGCCAGGGTG 
CTGAGGCATG GGCCAGCCAA GGCCATCAGC ATGTCTCGGA CTGACCCGCC GGCTGTCAAC 
GGGGCCTCTC TCGGCCCATC CATCTCGGAA CCCGACCTGA CTAGTGTGAA GGAGCGGGTC 
AAAAAAGAGC CTGTGAAGGA GAGACCTGTG TCTGAAATGT TTTCCCTGGA AGACAGCATT 
ATAGAGAGAG AGATGATGAT CAGGAATCTA GAGAAGCAGA AGATGGCAGG CCTGGAGGCA 
CAGAAGAGGC CGCTGATGTT GGCAGCATTG AATGGGCTCT CGGTGGCTCG AGTCTCAGGG 
CGGGAAGAGA ATCGAGTTGA TGCCACCCGG GTTCCCATGG ACGAGAGGTT CAGAACCCTG 
AAGAAGAAAC TAGAAGAGGG AATGGTGTTC ACAGAATATG AGCAAATTCC AAAGAAAAAG 
GCGAATGGCA TTTTCAGCAC AGCAGCTCTG CCAGAAAACG CCGAGCGCAG CCGAATCCGT 
GAAGTTGTCC CCTATGAGGA GAATCGAGTA GAGCTGATAC CAACCAAAGA AAATAACACA 
GGATACATTA ATGCCTCCCA CATCAAGGTG GTGGTTGGCG GGGCAGAATG GCACTACATA 
GCCACCCAGG GGCCCCTGCC ACACACGTGC CACGACTTCT GGCAGATGGT GTGGGAGCAG 
GGAGTGAATG TGATTGCCAT GGTCACTGCA GAGGAGGAGG GTGGACGAAC CAAAAGCCAC 
CGATACTGGC CCAAACTAGG TTCAAAGCAC AGCTCAGCCA CCTATGGCAA GTTCAAGGTC 
ACCACGAAGT TTCGAACGGA TTCTGTTTGC TATGCAACCA CGGGCTTGAA GGTCAAGCAC 
CTTTTGTCTG GGCAAGAAAG GACGGTGTGG CATTTACAAT ATACTGACTG GCCAGATCAC 
GGCTGTCCAG AAGATGTCCA AGGATTTTTA TCCTACTTGG AGGAGATCCA GTCGGTCCGT 
CGCCATACCA ACAGCATGCT GGAAGGCACC AAGAACCGGC ACCCGCCCAT CGTGGTCCAC 
TGTAGTGCTG GGGTGGGAAG GACCGGCGTG CTCATTCTTT CTGAGCTGAT GATCTACTGC 
TTGGAACATA ACGAAAAGGT GGAAGTGCCC ATGATGCTGA GGCTCCTCAG GGAGCAGAGG 
ATGTTCATGA TCCAGACTAT CGCTCAGTAC AAGTTTGTCT ACCAAGTCCT CATCCAGTTC 
CTCCAAAACT CCAGACTCAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Cancer cell32(4)460-473.e6(2017 Oct)
Mello SS,Valente LJ,Raj N,Seoane JA,Flowers BM,McClendon J,Bieging-Rolett KT,Lee J,Ivanochko D,Kozak MM,Chang DT,Longacre TA,Koong AC,Arrowsmith CH,Kim SK,Vogel H,Wood LD,Hruban RH,Curtis C,Attardi LD

The PTPN14 Tumor Suppressor Is a Degradation Target of Human Papillomavirus E7.
Journal of virology91(7)(2017 Apr)
Szalm?s A,Tomai? V,Basukala O,Massimi P,Mittal S,K?nya J,Banks L

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PTPN14 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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