NLGN2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NLGN2
Entrez Gene ID	57555
Full Name	neuroligin 2
General protein information	Preferred Names neuroligin 2 Names neuroligin-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.1
Summary	This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008].
Disorder MIM:	606479

mRNA and Protein(s)

mRNA	Protein	Name
NM_020795.4	NP_065846.1	neuroligin-2 precursor
XM_005256744.4	XP_005256801.1	neuroligin-2 isoform X1
NM_020795.3	NP_065846.1	neuroligin-2 precursor
XM_017024897.1	XP_016880386.1	neuroligin-2 isoform X2
XM_005256744.3	XP_005256801.1	neuroligin-2 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NLGN2	XP_849499.2
Mus musculus (house mouse)	Nlgn2	NP_942562.2
Homo sapiens (human)	NLGN2	NP_065846.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003568	XP_562412.4
Pan troglodytes (chimpanzee)	NLGN2	XP_523830.3
	NLGN2	XP_001108431.2
Bos taurus (cattle)	NLGN2	NP_001178171.1
Rattus norvegicus (Norway rat)	Nlgn2	NP_446444.1
Danio rerio (zebrafish)	nlgn2a	NP_001159808.1
Danio rerio (zebrafish)	nlgn2b	NP_001159801.1
Drosophila melanogaster (fruit fly)	CG34127	NP_001036685.2
Xenopus tropicalis (tropical clawed frog)	nlgn2	XP_002944465.2

Gene Ontology
Bibliography

Related articles in PubMed

Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility.
Heshmati M, Aleyasin H, Menard C, Christoffel DJ, Flanigan ME, Pfau ML, Hodes GE, Lepack AE, Bicks LK, Takahashi A, Chandra R, Turecki G, Lobo MK, Maze I, Golden SA, Russo SJ
Proceedings of the National Academy of Sciences of the United States of America(2018 Jan)

Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges.
Gangwar SP, Zhong X, Seshadrinathan S, Chen H, Machius M, Rudenko G
Neuron94(6)1132-1141.e4(2017 Jun)

Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity.
Parente DJ, Garriga C, Baskin B, Douglas G, Cho MT, Araujo GC, Shinawi M
American journal of medical genetics. Part A173(1)213-216(2017 Jan)

Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses.
Nguyen QA, Horn ME, Nicoll RA
eLife5(2016 11)

The down-regulation of neuroligin-2 and the correlative clinical significance of serum GABA over-expression in Hirschsprung's disease.
Yang H, Niu J, Wang J, Zhang F, Zhang Q, Zhang W, Li A
Neurochemical research39(8)1451-7(2014 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MDGAs regulate the formation of neuroligin-neurexin trans-synaptic bridges by sterically blocking access of neurexins to neuroligins.
Title: Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges.

This is the first report of an NLGN2 nonsense variant in humans, adding to the accumulating evidence that links synaptic proteins with a spectrum of neurodevelopmental phenotypes.
Title: Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity.

e found that NLGN3 function at inhibitory synapses in rat CA1 depends on the presence of NLGN2 and identified a domain in the extracellular region that accounted for this functional difference between NLGN2 and 3 specifically at inhibitory synapses.
Title: Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses.

Neuroligin-2 was down-regulated in aganglionic colonic segments from Hirschsprung's disease patients.
Title: The down-regulation of neuroligin-2 and the correlative clinical significance of serum GABA over-expression in Hirschsprung's disease.

Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic beta cell function
Title: Transcellular neuroligin-2 interactions enhance insulin secretion and are integral to pancreatic ? cell function.

The following NLGN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NLGN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00814	NM_020795.4 Latest version!	Homo sapiens neuroligin 2 (NLGN2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$587.30 $839.00
OHu49908	XM_005256744.4 Latest version!	Homo sapiens neuroligin 2 (NLGN2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu87004	XM_017024897.1 Latest version!	Homo sapiens neuroligin 2 (NLGN2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu00814	NM_020795.3	Homo sapiens neuroligin 2 (NLGN2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$587.30 $839.00
OHu49908	XM_005256744.3	Homo sapiens neuroligin 2 (NLGN2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NLGN2 ( NM_020795.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065846.1 Homo sapiens neuroligin 2 (NLGN2), mRNA.

Price & Availability↑

CloneID	OHu00814
Clone ID Related Accession (Same CDS sequence)	NM_020795.4 , NM_020795.3
Accession Version	NM_020795.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2508bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	neuroligin-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC113189.11, AF376802.1, BM800364.1, DR763679.1, EL949788.1, AA447769.1 and AI613237.1. On Nov 22, 2018 this sequence version replaced NM_020795.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF376802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000302926.7/ ENSP00000305288.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGGTC CGCTCACAAA AAAACGTGAC 
GAGGCGACGC TCAATCCGCC AGACACAGAT ATCCGTGACC CTGGGAAGAA GCCTGTGATG 
CTGTTTCTCC ATGGCGGCTC CTACATGGAG GGGACCGGAA ACATGTTCGA TGGCTCAGTC 
CTGGCTGCCT ATGGCAACGT CATTGTAGCC ACGCTCAACT ACCGTCTTGG GGTGCTCGGT 
TTTCTCAGCA CCGGGGACCA GGCTGCAAAA GGCAACTATG GGCTCCTGGA CCAGATCCAG 
GCCCTGCGCT GGCTCAGTGA AAACATCGCC CACTTTGGGG GCGACCCCGA GCGTATCACC 
ATCTTTGGTT CCGGGGCAGG GGCCTCCTGC GTCAACCTTC TGATCCTCTC CCACCATTCA 
GAAGGGCTGT TCCAGAAGGC CATCGCCCAG AGTGGCACCG CCATTTCCAG CTGGTCTGTC 
AACTACCAGC CGCTCAAGTA CACGCGGCTG CTGGCAGCCA AGGTGGGCTG TGACCGAGAG 
GACAGCGCTG AAGCTGTGGA GTGTCTGCGC CGGAAGCCCT CCCGGGAGCT GGTGGACCAG 
GACGTGCAGC CTGCCCGCTA CCACATCGCC TTTGGGCCCG TGGTGGATGG CGACGTGGTC 
CCCGATGACC CTGAGATCCT CATGCAGCAG GGAGAATTCC TCAACTACGA CATGCTCATC 
GGCGTCAACC AGGGAGAGGG CCTCAAGTTC GTGGAGGACT CTGCAGAGAG CGAGGACGGT 
GTGTCTGCCA GCGCCTTTGA CTTCACTGTC TCCAACTTTG TGGACAACCT GTATGGCTAC 
CCGGAAGGCA AGGATGTGCT TCGGGAGACC ATCAAGTTTA TGTACACAGA CTGGGCCGAC 
CGGGACAATG GCGAAATGCG CCGCAAAACC CTGCTGGCGC TCTTTACTGA CCACCAATGG 
GTGGCACCAG CTGTGGCCAC TGCCAAGCTG CACGCCGACT ACCAGTCTCC CGTCTACTTT 
TACACCTTCT ACCACCACTG CCAGGCGGAG GGCCGGCCTG AGTGGGCAGA TGCGGCGCAC 
GGGGATGAAC TGCCCTATGT CTTTGGCGTG CCCATGGTGG GTGCCACCGA CCTCTTCCCC 
TGTAACTTCT CCAAGAATGA CGTCATGCTC AGTGCCGTGG TCATGACCTA CTGGACCAAC 
TTCGCCAAGA CTGGGGACCC CAACCAGCCG GTGCCGCAGG ATACCAAGTT CATCCACACC 
AAGCCCAATC GCTTCGAGGA GGTGGTGTGG AGCAAATTCA ACAGCAAGGA GAAGCAGTAT 
CTGCACATAG GCCTGAAGCC ACGCGTGCGT GACAACTACC GCGCCAACAA GGTGGCCTTC 
TGGCTGGAGC TCGTGCCCCA CCTGCACAAC CTGCACACGG AGCTCTTCAC CACCACCACG 
CGCCTGCCTC CCTACGCCAC GCGCTGGCCG CCTCGTCCCC CCGCTGGCGC CCCGGGCACA 
CGCCGGCCCC CGCCGCCTGC CACCCTGCCT CCCGAGCCCG AGCCCGAGCC CGGCCCAAGG 
GCCTATGACC GCTTCCCCGG GGACTCACGG GACTACTCCA CGGAGCTGAG CGTCACCGTG 
GCCGTGGGTG CCTCCCTCCT CTTCCTCAAC ATCCTGGCCT TTGCTGCCCT CTACTACAAG 
CGGGACCGGC GGCAGGAGCT GCGGTGCAGG CGGCTTAGCC CACCTGGCGG CTCAGGCTCT 
GGCGTGCCTG GTGGGGGCCC CCTGCTCCCC GCCGCGGGCC GTGAGCTGCC ACCAGAGGAG 
GAGCTGGTGT CACTGCAGCT GAAGCGGGGT GGTGGCGTCG GGGCGGACCC TGCCGAGGCT 
CTGCGCCCTG CCTGCCCGCC CGACTACACC CTGGCCCTGC GCCGGGCACC GGACGATGTG 
CCTCTCTTGG CCCCCGGGGC CCTGACCCTG CTGCCCAGTG GCCTGGGGCC ACCGCCACCC 
CCACCGCCCC CCTCCCTTCA TCCCTTCGGG CCCTTCCCCC CGCCCCCTCC CACCGCCACC 
AGCCACAACA ACACGCTACC CCACCCCCAC TCCACCACTC GGGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065846.1
CDS	412..2919
Translation	MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV

Target ORF information:

RefSeq Version	NM_020795.4
Organism	Homo sapiens(human)
Definition	Homo sapiens neuroligin 2 (NLGN2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020795.4

ORF Insert Sequence:

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGGTC CGCTCACAAA AAAACGTGAC 
GAGGCGACGC TCAATCCGCC AGACACAGAT ATCCGTGACC CTGGGAAGAA GCCTGTGATG 
CTGTTTCTCC ATGGCGGCTC CTACATGGAG GGGACCGGAA ACATGTTCGA TGGCTCAGTC 
CTGGCTGCCT ATGGCAACGT CATTGTAGCC ACGCTCAACT ACCGTCTTGG GGTGCTCGGT 
TTTCTCAGCA CCGGGGACCA GGCTGCAAAA GGCAACTATG GGCTCCTGGA CCAGATCCAG 
GCCCTGCGCT GGCTCAGTGA AAACATCGCC CACTTTGGGG GCGACCCCGA GCGTATCACC 
ATCTTTGGTT CCGGGGCAGG GGCCTCCTGC GTCAACCTTC TGATCCTCTC CCACCATTCA 
GAAGGGCTGT TCCAGAAGGC CATCGCCCAG AGTGGCACCG CCATTTCCAG CTGGTCTGTC 
AACTACCAGC CGCTCAAGTA CACGCGGCTG CTGGCAGCCA AGGTGGGCTG TGACCGAGAG 
GACAGCGCTG AAGCTGTGGA GTGTCTGCGC CGGAAGCCCT CCCGGGAGCT GGTGGACCAG 
GACGTGCAGC CTGCCCGCTA CCACATCGCC TTTGGGCCCG TGGTGGATGG CGACGTGGTC 
CCCGATGACC CTGAGATCCT CATGCAGCAG GGAGAATTCC TCAACTACGA CATGCTCATC 
GGCGTCAACC AGGGAGAGGG CCTCAAGTTC GTGGAGGACT CTGCAGAGAG CGAGGACGGT 
GTGTCTGCCA GCGCCTTTGA CTTCACTGTC TCCAACTTTG TGGACAACCT GTATGGCTAC 
CCGGAAGGCA AGGATGTGCT TCGGGAGACC ATCAAGTTTA TGTACACAGA CTGGGCCGAC 
CGGGACAATG GCGAAATGCG CCGCAAAACC CTGCTGGCGC TCTTTACTGA CCACCAATGG 
GTGGCACCAG CTGTGGCCAC TGCCAAGCTG CACGCCGACT ACCAGTCTCC CGTCTACTTT 
TACACCTTCT ACCACCACTG CCAGGCGGAG GGCCGGCCTG AGTGGGCAGA TGCGGCGCAC 
GGGGATGAAC TGCCCTATGT CTTTGGCGTG CCCATGGTGG GTGCCACCGA CCTCTTCCCC 
TGTAACTTCT CCAAGAATGA CGTCATGCTC AGTGCCGTGG TCATGACCTA CTGGACCAAC 
TTCGCCAAGA CTGGGGACCC CAACCAGCCG GTGCCGCAGG ATACCAAGTT CATCCACACC 
AAGCCCAATC GCTTCGAGGA GGTGGTGTGG AGCAAATTCA ACAGCAAGGA GAAGCAGTAT 
CTGCACATAG GCCTGAAGCC ACGCGTGCGT GACAACTACC GCGCCAACAA GGTGGCCTTC 
TGGCTGGAGC TCGTGCCCCA CCTGCACAAC CTGCACACGG AGCTCTTCAC CACCACCACG 
CGCCTGCCTC CCTACGCCAC GCGCTGGCCG CCTCGTCCCC CCGCTGGCGC CCCGGGCACA 
CGCCGGCCCC CGCCGCCTGC CACCCTGCCT CCCGAGCCCG AGCCCGAGCC CGGCCCAAGG 
GCCTATGACC GCTTCCCCGG GGACTCACGG GACTACTCCA CGGAGCTGAG CGTCACCGTG 
GCCGTGGGTG CCTCCCTCCT CTTCCTCAAC ATCCTGGCCT TTGCTGCCCT CTACTACAAG 
CGGGACCGGC GGCAGGAGCT GCGGTGCAGG CGGCTTAGCC CACCTGGCGG CTCAGGCTCT 
GGCGTGCCTG GTGGGGGCCC CCTGCTCCCC GCCGCGGGCC GTGAGCTGCC ACCAGAGGAG 
GAGCTGGTGT CACTGCAGCT GAAGCGGGGT GGTGGCGTCG GGGCGGACCC TGCCGAGGCT 
CTGCGCCCTG CCTGCCCGCC CGACTACACC CTGGCCCTGC GCCGGGCACC GGACGATGTG 
CCTCTCTTGG CCCCCGGGGC CCTGACCCTG CTGCCCAGTG GCCTGGGGCC ACCGCCACCC 
CCACCGCCCC CCTCCCTTCA TCCCTTCGGG CCCTTCCCCC CGCCCCCTCC CACCGCCACC 
AGCCACAACA ACACGCTACC CCACCCCCAC TCCACCACTC GGGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLGN2 ( NM_020795.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065846.1 Homo sapiens neuroligin 2 (NLGN2), mRNA.

Price & Availability↑

CloneID	OHu00814
Clone ID Related Accession (Same CDS sequence)	NM_020795.4 , NM_020795.3
Accession Version	NM_020795.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2508bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	neuroligin-2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF376802.1, AC113189.11, BM800364.1, DR763679.1, EL949788.1, AA447769.1, AI613237.1 and BI868885.1. On Jul 26, 2013 this sequence version replaced NM_020795.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF376802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGGTC CGCTCACAAA AAAACGTGAC 
GAGGCGACGC TCAATCCGCC AGACACAGAT ATCCGTGACC CTGGGAAGAA GCCTGTGATG 
CTGTTTCTCC ATGGCGGCTC CTACATGGAG GGGACCGGAA ACATGTTCGA TGGCTCAGTC 
CTGGCTGCCT ATGGCAACGT CATTGTAGCC ACGCTCAACT ACCGTCTTGG GGTGCTCGGT 
TTTCTCAGCA CCGGGGACCA GGCTGCAAAA GGCAACTATG GGCTCCTGGA CCAGATCCAG 
GCCCTGCGCT GGCTCAGTGA AAACATCGCC CACTTTGGGG GCGACCCCGA GCGTATCACC 
ATCTTTGGTT CCGGGGCAGG GGCCTCCTGC GTCAACCTTC TGATCCTCTC CCACCATTCA 
GAAGGGCTGT TCCAGAAGGC CATCGCCCAG AGTGGCACCG CCATTTCCAG CTGGTCTGTC 
AACTACCAGC CGCTCAAGTA CACGCGGCTG CTGGCAGCCA AGGTGGGCTG TGACCGAGAG 
GACAGCGCTG AAGCTGTGGA GTGTCTGCGC CGGAAGCCCT CCCGGGAGCT GGTGGACCAG 
GACGTGCAGC CTGCCCGCTA CCACATCGCC TTTGGGCCCG TGGTGGATGG CGACGTGGTC 
CCCGATGACC CTGAGATCCT CATGCAGCAG GGAGAATTCC TCAACTACGA CATGCTCATC 
GGCGTCAACC AGGGAGAGGG CCTCAAGTTC GTGGAGGACT CTGCAGAGAG CGAGGACGGT 
GTGTCTGCCA GCGCCTTTGA CTTCACTGTC TCCAACTTTG TGGACAACCT GTATGGCTAC 
CCGGAAGGCA AGGATGTGCT TCGGGAGACC ATCAAGTTTA TGTACACAGA CTGGGCCGAC 
CGGGACAATG GCGAAATGCG CCGCAAAACC CTGCTGGCGC TCTTTACTGA CCACCAATGG 
GTGGCACCAG CTGTGGCCAC TGCCAAGCTG CACGCCGACT ACCAGTCTCC CGTCTACTTT 
TACACCTTCT ACCACCACTG CCAGGCGGAG GGCCGGCCTG AGTGGGCAGA TGCGGCGCAC 
GGGGATGAAC TGCCCTATGT CTTTGGCGTG CCCATGGTGG GTGCCACCGA CCTCTTCCCC 
TGTAACTTCT CCAAGAATGA CGTCATGCTC AGTGCCGTGG TCATGACCTA CTGGACCAAC 
TTCGCCAAGA CTGGGGACCC CAACCAGCCG GTGCCGCAGG ATACCAAGTT CATCCACACC 
AAGCCCAATC GCTTCGAGGA GGTGGTGTGG AGCAAATTCA ACAGCAAGGA GAAGCAGTAT 
CTGCACATAG GCCTGAAGCC ACGCGTGCGT GACAACTACC GCGCCAACAA GGTGGCCTTC 
TGGCTGGAGC TCGTGCCCCA CCTGCACAAC CTGCACACGG AGCTCTTCAC CACCACCACG 
CGCCTGCCTC CCTACGCCAC GCGCTGGCCG CCTCGTCCCC CCGCTGGCGC CCCGGGCACA 
CGCCGGCCCC CGCCGCCTGC CACCCTGCCT CCCGAGCCCG AGCCCGAGCC CGGCCCAAGG 
GCCTATGACC GCTTCCCCGG GGACTCACGG GACTACTCCA CGGAGCTGAG CGTCACCGTG 
GCCGTGGGTG CCTCCCTCCT CTTCCTCAAC ATCCTGGCCT TTGCTGCCCT CTACTACAAG 
CGGGACCGGC GGCAGGAGCT GCGGTGCAGG CGGCTTAGCC CACCTGGCGG CTCAGGCTCT 
GGCGTGCCTG GTGGGGGCCC CCTGCTCCCC GCCGCGGGCC GTGAGCTGCC ACCAGAGGAG 
GAGCTGGTGT CACTGCAGCT GAAGCGGGGT GGTGGCGTCG GGGCGGACCC TGCCGAGGCT 
CTGCGCCCTG CCTGCCCGCC CGACTACACC CTGGCCCTGC GCCGGGCACC GGACGATGTG 
CCTCTCTTGG CCCCCGGGGC CCTGACCCTG CTGCCCAGTG GCCTGGGGCC ACCGCCACCC 
CCACCGCCCC CCTCCCTTCA TCCCTTCGGG CCCTTCCCCC CGCCCCCTCC CACCGCCACC 
AGCCACAACA ACACGCTACC CCACCCCCAC TCCACCACTC GGGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065846.1
CDS	74..2581
Translation	MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV

Target ORF information:

RefSeq Version	NM_020795.3
Organism	Homo sapiens(human)
Definition	Homo sapiens neuroligin 2 (NLGN2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020795.3

ORF Insert Sequence:

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGGTC CGCTCACAAA AAAACGTGAC 
GAGGCGACGC TCAATCCGCC AGACACAGAT ATCCGTGACC CTGGGAAGAA GCCTGTGATG 
CTGTTTCTCC ATGGCGGCTC CTACATGGAG GGGACCGGAA ACATGTTCGA TGGCTCAGTC 
CTGGCTGCCT ATGGCAACGT CATTGTAGCC ACGCTCAACT ACCGTCTTGG GGTGCTCGGT 
TTTCTCAGCA CCGGGGACCA GGCTGCAAAA GGCAACTATG GGCTCCTGGA CCAGATCCAG 
GCCCTGCGCT GGCTCAGTGA AAACATCGCC CACTTTGGGG GCGACCCCGA GCGTATCACC 
ATCTTTGGTT CCGGGGCAGG GGCCTCCTGC GTCAACCTTC TGATCCTCTC CCACCATTCA 
GAAGGGCTGT TCCAGAAGGC CATCGCCCAG AGTGGCACCG CCATTTCCAG CTGGTCTGTC 
AACTACCAGC CGCTCAAGTA CACGCGGCTG CTGGCAGCCA AGGTGGGCTG TGACCGAGAG 
GACAGCGCTG AAGCTGTGGA GTGTCTGCGC CGGAAGCCCT CCCGGGAGCT GGTGGACCAG 
GACGTGCAGC CTGCCCGCTA CCACATCGCC TTTGGGCCCG TGGTGGATGG CGACGTGGTC 
CCCGATGACC CTGAGATCCT CATGCAGCAG GGAGAATTCC TCAACTACGA CATGCTCATC 
GGCGTCAACC AGGGAGAGGG CCTCAAGTTC GTGGAGGACT CTGCAGAGAG CGAGGACGGT 
GTGTCTGCCA GCGCCTTTGA CTTCACTGTC TCCAACTTTG TGGACAACCT GTATGGCTAC 
CCGGAAGGCA AGGATGTGCT TCGGGAGACC ATCAAGTTTA TGTACACAGA CTGGGCCGAC 
CGGGACAATG GCGAAATGCG CCGCAAAACC CTGCTGGCGC TCTTTACTGA CCACCAATGG 
GTGGCACCAG CTGTGGCCAC TGCCAAGCTG CACGCCGACT ACCAGTCTCC CGTCTACTTT 
TACACCTTCT ACCACCACTG CCAGGCGGAG GGCCGGCCTG AGTGGGCAGA TGCGGCGCAC 
GGGGATGAAC TGCCCTATGT CTTTGGCGTG CCCATGGTGG GTGCCACCGA CCTCTTCCCC 
TGTAACTTCT CCAAGAATGA CGTCATGCTC AGTGCCGTGG TCATGACCTA CTGGACCAAC 
TTCGCCAAGA CTGGGGACCC CAACCAGCCG GTGCCGCAGG ATACCAAGTT CATCCACACC 
AAGCCCAATC GCTTCGAGGA GGTGGTGTGG AGCAAATTCA ACAGCAAGGA GAAGCAGTAT 
CTGCACATAG GCCTGAAGCC ACGCGTGCGT GACAACTACC GCGCCAACAA GGTGGCCTTC 
TGGCTGGAGC TCGTGCCCCA CCTGCACAAC CTGCACACGG AGCTCTTCAC CACCACCACG 
CGCCTGCCTC CCTACGCCAC GCGCTGGCCG CCTCGTCCCC CCGCTGGCGC CCCGGGCACA 
CGCCGGCCCC CGCCGCCTGC CACCCTGCCT CCCGAGCCCG AGCCCGAGCC CGGCCCAAGG 
GCCTATGACC GCTTCCCCGG GGACTCACGG GACTACTCCA CGGAGCTGAG CGTCACCGTG 
GCCGTGGGTG CCTCCCTCCT CTTCCTCAAC ATCCTGGCCT TTGCTGCCCT CTACTACAAG 
CGGGACCGGC GGCAGGAGCT GCGGTGCAGG CGGCTTAGCC CACCTGGCGG CTCAGGCTCT 
GGCGTGCCTG GTGGGGGCCC CCTGCTCCCC GCCGCGGGCC GTGAGCTGCC ACCAGAGGAG 
GAGCTGGTGT CACTGCAGCT GAAGCGGGGT GGTGGCGTCG GGGCGGACCC TGCCGAGGCT 
CTGCGCCCTG CCTGCCCGCC CGACTACACC CTGGCCCTGC GCCGGGCACC GGACGATGTG 
CCTCTCTTGG CCCCCGGGGC CCTGACCCTG CTGCCCAGTG GCCTGGGGCC ACCGCCACCC 
CCACCGCCCC CCTCCCTTCA TCCCTTCGGG CCCTTCCCCC CGCCCCCTCC CACCGCCACC 
AGCCACAACA ACACGCTACC CCACCCCCAC TCCACCACTC GGGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLGN2 ( XM_005256744.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256801.1 Homo sapiens neuroligin 2 (NLGN2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49908
Clone ID Related Accession (Same CDS sequence)	XM_005256744.4 , XM_005256744.3
Accession Version	XM_005256744.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2457bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	neuroligin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005256744.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGATA TCCGTGACCC TGGGAAGAAG 
CCTGTGATGC TGTTTCTCCA TGGCGGCTCC TACATGGAGG GGACCGGAAA CATGTTCGAT 
GGCTCAGTCC TGGCTGCCTA TGGCAACGTC ATTGTAGCCA CGCTCAACTA CCGTCTTGGG 
GTGCTCGGTT TTCTCAGCAC CGGGGACCAG GCTGCAAAAG GCAACTATGG GCTCCTGGAC 
CAGATCCAGG CCCTGCGCTG GCTCAGTGAA AACATCGCCC ACTTTGGGGG CGACCCCGAG 
CGTATCACCA TCTTTGGTTC CGGGGCAGGG GCCTCCTGCG TCAACCTTCT GATCCTCTCC 
CACCATTCAG AAGGGCTGTT CCAGAAGGCC ATCGCCCAGA GTGGCACCGC CATTTCCAGC 
TGGTCTGTCA ACTACCAGCC GCTCAAGTAC ACGCGGCTGC TGGCAGCCAA GGTGGGCTGT 
GACCGAGAGG ACAGCGCTGA AGCTGTGGAG TGTCTGCGCC GGAAGCCCTC CCGGGAGCTG 
GTGGACCAGG ACGTGCAGCC TGCCCGCTAC CACATCGCCT TTGGGCCCGT GGTGGATGGC 
GACGTGGTCC CCGATGACCC TGAGATCCTC ATGCAGCAGG GAGAATTCCT CAACTACGAC 
ATGCTCATCG GCGTCAACCA GGGAGAGGGC CTCAAGTTCG TGGAGGACTC TGCAGAGAGC 
GAGGACGGTG TGTCTGCCAG CGCCTTTGAC TTCACTGTCT CCAACTTTGT GGACAACCTG 
TATGGCTACC CGGAAGGCAA GGATGTGCTT CGGGAGACCA TCAAGTTTAT GTACACAGAC 
TGGGCCGACC GGGACAATGG CGAAATGCGC CGCAAAACCC TGCTGGCGCT CTTTACTGAC 
CACCAATGGG TGGCACCAGC TGTGGCCACT GCCAAGCTGC ACGCCGACTA CCAGTCTCCC 
GTCTACTTTT ACACCTTCTA CCACCACTGC CAGGCGGAGG GCCGGCCTGA GTGGGCAGAT 
GCGGCGCACG GGGATGAACT GCCCTATGTC TTTGGCGTGC CCATGGTGGG TGCCACCGAC 
CTCTTCCCCT GTAACTTCTC CAAGAATGAC GTCATGCTCA GTGCCGTGGT CATGACCTAC 
TGGACCAACT TCGCCAAGAC TGGGGACCCC AACCAGCCGG TGCCGCAGGA TACCAAGTTC 
ATCCACACCA AGCCCAATCG CTTCGAGGAG GTGGTGTGGA GCAAATTCAA CAGCAAGGAG 
AAGCAGTATC TGCACATAGG CCTGAAGCCA CGCGTGCGTG ACAACTACCG CGCCAACAAG 
GTGGCCTTCT GGCTGGAGCT CGTGCCCCAC CTGCACAACC TGCACACGGA GCTCTTCACC 
ACCACCACGC GCCTGCCTCC CTACGCCACG CGCTGGCCGC CTCGTCCCCC CGCTGGCGCC 
CCGGGCACAC GCCGGCCCCC GCCGCCTGCC ACCCTGCCTC CCGAGCCCGA GCCCGAGCCC 
GGCCCAAGGG CCTATGACCG CTTCCCCGGG GACTCACGGG ACTACTCCAC GGAGCTGAGC 
GTCACCGTGG CCGTGGGTGC CTCCCTCCTC TTCCTCAACA TCCTGGCCTT TGCTGCCCTC 
TACTACAAGC GGGACCGGCG GCAGGAGCTG CGGTGCAGGC GGCTTAGCCC ACCTGGCGGC 
TCAGGCTCTG GCGTGCCTGG TGGGGGCCCC CTGCTCCCCG CCGCGGGCCG TGAGCTGCCA 
CCAGAGGAGG AGCTGGTGTC ACTGCAGCTG AAGCGGGGTG GTGGCGTCGG GGCGGACCCT 
GCCGAGGCTC TGCGCCCTGC CTGCCCGCCC GACTACACCC TGGCCCTGCG CCGGGCACCG 
GACGATGTGC CTCTCTTGGC CCCCGGGGCC CTGACCCTGC TGCCCAGTGG CCTGGGGCCA 
CCGCCACCCC CACCGCCCCC CTCCCTTCAT CCCTTCGGGC CCTTCCCCCC GCCCCCTCCC 
ACCGCCACCA GCCACAACAA CACGCTACCC CACCCCCACT CCACCACTCG GGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256801.1
CDS	76..2532
Translation	MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV

Target ORF information:

RefSeq Version	XM_005256744.4
Organism	Homo sapiens(human)
Definition	Homo sapiens neuroligin 2 (NLGN2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256744.4

ORF Insert Sequence:

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGATA TCCGTGACCC TGGGAAGAAG 
CCTGTGATGC TGTTTCTCCA TGGCGGCTCC TACATGGAGG GGACCGGAAA CATGTTCGAT 
GGCTCAGTCC TGGCTGCCTA TGGCAACGTC ATTGTAGCCA CGCTCAACTA CCGTCTTGGG 
GTGCTCGGTT TTCTCAGCAC CGGGGACCAG GCTGCAAAAG GCAACTATGG GCTCCTGGAC 
CAGATCCAGG CCCTGCGCTG GCTCAGTGAA AACATCGCCC ACTTTGGGGG CGACCCCGAG 
CGTATCACCA TCTTTGGTTC CGGGGCAGGG GCCTCCTGCG TCAACCTTCT GATCCTCTCC 
CACCATTCAG AAGGGCTGTT CCAGAAGGCC ATCGCCCAGA GTGGCACCGC CATTTCCAGC 
TGGTCTGTCA ACTACCAGCC GCTCAAGTAC ACGCGGCTGC TGGCAGCCAA GGTGGGCTGT 
GACCGAGAGG ACAGCGCTGA AGCTGTGGAG TGTCTGCGCC GGAAGCCCTC CCGGGAGCTG 
GTGGACCAGG ACGTGCAGCC TGCCCGCTAC CACATCGCCT TTGGGCCCGT GGTGGATGGC 
GACGTGGTCC CCGATGACCC TGAGATCCTC ATGCAGCAGG GAGAATTCCT CAACTACGAC 
ATGCTCATCG GCGTCAACCA GGGAGAGGGC CTCAAGTTCG TGGAGGACTC TGCAGAGAGC 
GAGGACGGTG TGTCTGCCAG CGCCTTTGAC TTCACTGTCT CCAACTTTGT GGACAACCTG 
TATGGCTACC CGGAAGGCAA GGATGTGCTT CGGGAGACCA TCAAGTTTAT GTACACAGAC 
TGGGCCGACC GGGACAATGG CGAAATGCGC CGCAAAACCC TGCTGGCGCT CTTTACTGAC 
CACCAATGGG TGGCACCAGC TGTGGCCACT GCCAAGCTGC ACGCCGACTA CCAGTCTCCC 
GTCTACTTTT ACACCTTCTA CCACCACTGC CAGGCGGAGG GCCGGCCTGA GTGGGCAGAT 
GCGGCGCACG GGGATGAACT GCCCTATGTC TTTGGCGTGC CCATGGTGGG TGCCACCGAC 
CTCTTCCCCT GTAACTTCTC CAAGAATGAC GTCATGCTCA GTGCCGTGGT CATGACCTAC 
TGGACCAACT TCGCCAAGAC TGGGGACCCC AACCAGCCGG TGCCGCAGGA TACCAAGTTC 
ATCCACACCA AGCCCAATCG CTTCGAGGAG GTGGTGTGGA GCAAATTCAA CAGCAAGGAG 
AAGCAGTATC TGCACATAGG CCTGAAGCCA CGCGTGCGTG ACAACTACCG CGCCAACAAG 
GTGGCCTTCT GGCTGGAGCT CGTGCCCCAC CTGCACAACC TGCACACGGA GCTCTTCACC 
ACCACCACGC GCCTGCCTCC CTACGCCACG CGCTGGCCGC CTCGTCCCCC CGCTGGCGCC 
CCGGGCACAC GCCGGCCCCC GCCGCCTGCC ACCCTGCCTC CCGAGCCCGA GCCCGAGCCC 
GGCCCAAGGG CCTATGACCG CTTCCCCGGG GACTCACGGG ACTACTCCAC GGAGCTGAGC 
GTCACCGTGG CCGTGGGTGC CTCCCTCCTC TTCCTCAACA TCCTGGCCTT TGCTGCCCTC 
TACTACAAGC GGGACCGGCG GCAGGAGCTG CGGTGCAGGC GGCTTAGCCC ACCTGGCGGC 
TCAGGCTCTG GCGTGCCTGG TGGGGGCCCC CTGCTCCCCG CCGCGGGCCG TGAGCTGCCA 
CCAGAGGAGG AGCTGGTGTC ACTGCAGCTG AAGCGGGGTG GTGGCGTCGG GGCGGACCCT 
GCCGAGGCTC TGCGCCCTGC CTGCCCGCCC GACTACACCC TGGCCCTGCG CCGGGCACCG 
GACGATGTGC CTCTCTTGGC CCCCGGGGCC CTGACCCTGC TGCCCAGTGG CCTGGGGCCA 
CCGCCACCCC CACCGCCCCC CTCCCTTCAT CCCTTCGGGC CCTTCCCCCC GCCCCCTCCC 
ACCGCCACCA GCCACAACAA CACGCTACCC CACCCCCACT CCACCACTCG GGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLGN2 ( XM_005256744.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256801.1 Homo sapiens neuroligin 2 (NLGN2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49908
Clone ID Related Accession (Same CDS sequence)	XM_005256744.4 , XM_005256744.3
Accession Version	XM_005256744.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2457bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	neuroligin-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005256744.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGATA TCCGTGACCC TGGGAAGAAG 
CCTGTGATGC TGTTTCTCCA TGGCGGCTCC TACATGGAGG GGACCGGAAA CATGTTCGAT 
GGCTCAGTCC TGGCTGCCTA TGGCAACGTC ATTGTAGCCA CGCTCAACTA CCGTCTTGGG 
GTGCTCGGTT TTCTCAGCAC CGGGGACCAG GCTGCAAAAG GCAACTATGG GCTCCTGGAC 
CAGATCCAGG CCCTGCGCTG GCTCAGTGAA AACATCGCCC ACTTTGGGGG CGACCCCGAG 
CGTATCACCA TCTTTGGTTC CGGGGCAGGG GCCTCCTGCG TCAACCTTCT GATCCTCTCC 
CACCATTCAG AAGGGCTGTT CCAGAAGGCC ATCGCCCAGA GTGGCACCGC CATTTCCAGC 
TGGTCTGTCA ACTACCAGCC GCTCAAGTAC ACGCGGCTGC TGGCAGCCAA GGTGGGCTGT 
GACCGAGAGG ACAGCGCTGA AGCTGTGGAG TGTCTGCGCC GGAAGCCCTC CCGGGAGCTG 
GTGGACCAGG ACGTGCAGCC TGCCCGCTAC CACATCGCCT TTGGGCCCGT GGTGGATGGC 
GACGTGGTCC CCGATGACCC TGAGATCCTC ATGCAGCAGG GAGAATTCCT CAACTACGAC 
ATGCTCATCG GCGTCAACCA GGGAGAGGGC CTCAAGTTCG TGGAGGACTC TGCAGAGAGC 
GAGGACGGTG TGTCTGCCAG CGCCTTTGAC TTCACTGTCT CCAACTTTGT GGACAACCTG 
TATGGCTACC CGGAAGGCAA GGATGTGCTT CGGGAGACCA TCAAGTTTAT GTACACAGAC 
TGGGCCGACC GGGACAATGG CGAAATGCGC CGCAAAACCC TGCTGGCGCT CTTTACTGAC 
CACCAATGGG TGGCACCAGC TGTGGCCACT GCCAAGCTGC ACGCCGACTA CCAGTCTCCC 
GTCTACTTTT ACACCTTCTA CCACCACTGC CAGGCGGAGG GCCGGCCTGA GTGGGCAGAT 
GCGGCGCACG GGGATGAACT GCCCTATGTC TTTGGCGTGC CCATGGTGGG TGCCACCGAC 
CTCTTCCCCT GTAACTTCTC CAAGAATGAC GTCATGCTCA GTGCCGTGGT CATGACCTAC 
TGGACCAACT TCGCCAAGAC TGGGGACCCC AACCAGCCGG TGCCGCAGGA TACCAAGTTC 
ATCCACACCA AGCCCAATCG CTTCGAGGAG GTGGTGTGGA GCAAATTCAA CAGCAAGGAG 
AAGCAGTATC TGCACATAGG CCTGAAGCCA CGCGTGCGTG ACAACTACCG CGCCAACAAG 
GTGGCCTTCT GGCTGGAGCT CGTGCCCCAC CTGCACAACC TGCACACGGA GCTCTTCACC 
ACCACCACGC GCCTGCCTCC CTACGCCACG CGCTGGCCGC CTCGTCCCCC CGCTGGCGCC 
CCGGGCACAC GCCGGCCCCC GCCGCCTGCC ACCCTGCCTC CCGAGCCCGA GCCCGAGCCC 
GGCCCAAGGG CCTATGACCG CTTCCCCGGG GACTCACGGG ACTACTCCAC GGAGCTGAGC 
GTCACCGTGG CCGTGGGTGC CTCCCTCCTC TTCCTCAACA TCCTGGCCTT TGCTGCCCTC 
TACTACAAGC GGGACCGGCG GCAGGAGCTG CGGTGCAGGC GGCTTAGCCC ACCTGGCGGC 
TCAGGCTCTG GCGTGCCTGG TGGGGGCCCC CTGCTCCCCG CCGCGGGCCG TGAGCTGCCA 
CCAGAGGAGG AGCTGGTGTC ACTGCAGCTG AAGCGGGGTG GTGGCGTCGG GGCGGACCCT 
GCCGAGGCTC TGCGCCCTGC CTGCCCGCCC GACTACACCC TGGCCCTGCG CCGGGCACCG 
GACGATGTGC CTCTCTTGGC CCCCGGGGCC CTGACCCTGC TGCCCAGTGG CCTGGGGCCA 
CCGCCACCCC CACCGCCCCC CTCCCTTCAT CCCTTCGGGC CCTTCCCCCC GCCCCCTCCC 
ACCGCCACCA GCCACAACAA CACGCTACCC CACCCCCACT CCACCACTCG GGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256801.1
CDS	75..2531
Translation	MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV

Target ORF information:

RefSeq Version	XM_005256744.3
Organism	Homo sapiens(human)
Definition	Homo sapiens neuroligin 2 (NLGN2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256744.3

ORF Insert Sequence:

ATGTGGCTCC TGGCGCTGTG TCTGGTGGGG CTGGCGGGGG CTCAACGCGG GGGAGGGGGT 
CCCGGCGGCG GCGCCCCGGG CGGCCCCGGC CTGGGCCTCG GCAGCCTCGG CGAGGAGCGC 
TTCCCGGTGG TGAACACGGC CTACGGGCGA GTGCGCGGTG TGCGGCGCGA GCTCAACAAC 
GAGATCCTGG GCCCCGTCGT GCAGTTCTTG GGCGTGCCCT ACGCCACGCC GCCCCTGGGC 
GCCCGCCGCT TCCAGCCGCC TGAGGCGCCC GCCTCGTGGC CCGGCGTGCG CAACGCCACC 
ACCCTGCCGC CCGCCTGCCC GCAGAACCTG CACGGGGCGC TGCCCGCCAT CATGCTGCCT 
GTGTGGTTCA CCGACAACTT GGAGGCGGCC GCCACCTACG TGCAGAACCA GAGCGAGGAC 
TGCCTGTACC TCAACCTCTA CGTGCCCACC GAGGACGATA TCCGTGACCC TGGGAAGAAG 
CCTGTGATGC TGTTTCTCCA TGGCGGCTCC TACATGGAGG GGACCGGAAA CATGTTCGAT 
GGCTCAGTCC TGGCTGCCTA TGGCAACGTC ATTGTAGCCA CGCTCAACTA CCGTCTTGGG 
GTGCTCGGTT TTCTCAGCAC CGGGGACCAG GCTGCAAAAG GCAACTATGG GCTCCTGGAC 
CAGATCCAGG CCCTGCGCTG GCTCAGTGAA AACATCGCCC ACTTTGGGGG CGACCCCGAG 
CGTATCACCA TCTTTGGTTC CGGGGCAGGG GCCTCCTGCG TCAACCTTCT GATCCTCTCC 
CACCATTCAG AAGGGCTGTT CCAGAAGGCC ATCGCCCAGA GTGGCACCGC CATTTCCAGC 
TGGTCTGTCA ACTACCAGCC GCTCAAGTAC ACGCGGCTGC TGGCAGCCAA GGTGGGCTGT 
GACCGAGAGG ACAGCGCTGA AGCTGTGGAG TGTCTGCGCC GGAAGCCCTC CCGGGAGCTG 
GTGGACCAGG ACGTGCAGCC TGCCCGCTAC CACATCGCCT TTGGGCCCGT GGTGGATGGC 
GACGTGGTCC CCGATGACCC TGAGATCCTC ATGCAGCAGG GAGAATTCCT CAACTACGAC 
ATGCTCATCG GCGTCAACCA GGGAGAGGGC CTCAAGTTCG TGGAGGACTC TGCAGAGAGC 
GAGGACGGTG TGTCTGCCAG CGCCTTTGAC TTCACTGTCT CCAACTTTGT GGACAACCTG 
TATGGCTACC CGGAAGGCAA GGATGTGCTT CGGGAGACCA TCAAGTTTAT GTACACAGAC 
TGGGCCGACC GGGACAATGG CGAAATGCGC CGCAAAACCC TGCTGGCGCT CTTTACTGAC 
CACCAATGGG TGGCACCAGC TGTGGCCACT GCCAAGCTGC ACGCCGACTA CCAGTCTCCC 
GTCTACTTTT ACACCTTCTA CCACCACTGC CAGGCGGAGG GCCGGCCTGA GTGGGCAGAT 
GCGGCGCACG GGGATGAACT GCCCTATGTC TTTGGCGTGC CCATGGTGGG TGCCACCGAC 
CTCTTCCCCT GTAACTTCTC CAAGAATGAC GTCATGCTCA GTGCCGTGGT CATGACCTAC 
TGGACCAACT TCGCCAAGAC TGGGGACCCC AACCAGCCGG TGCCGCAGGA TACCAAGTTC 
ATCCACACCA AGCCCAATCG CTTCGAGGAG GTGGTGTGGA GCAAATTCAA CAGCAAGGAG 
AAGCAGTATC TGCACATAGG CCTGAAGCCA CGCGTGCGTG ACAACTACCG CGCCAACAAG 
GTGGCCTTCT GGCTGGAGCT CGTGCCCCAC CTGCACAACC TGCACACGGA GCTCTTCACC 
ACCACCACGC GCCTGCCTCC CTACGCCACG CGCTGGCCGC CTCGTCCCCC CGCTGGCGCC 
CCGGGCACAC GCCGGCCCCC GCCGCCTGCC ACCCTGCCTC CCGAGCCCGA GCCCGAGCCC 
GGCCCAAGGG CCTATGACCG CTTCCCCGGG GACTCACGGG ACTACTCCAC GGAGCTGAGC 
GTCACCGTGG CCGTGGGTGC CTCCCTCCTC TTCCTCAACA TCCTGGCCTT TGCTGCCCTC 
TACTACAAGC GGGACCGGCG GCAGGAGCTG CGGTGCAGGC GGCTTAGCCC ACCTGGCGGC 
TCAGGCTCTG GCGTGCCTGG TGGGGGCCCC CTGCTCCCCG CCGCGGGCCG TGAGCTGCCA 
CCAGAGGAGG AGCTGGTGTC ACTGCAGCTG AAGCGGGGTG GTGGCGTCGG GGCGGACCCT 
GCCGAGGCTC TGCGCCCTGC CTGCCCGCCC GACTACACCC TGGCCCTGCG CCGGGCACCG 
GACGATGTGC CTCTCTTGGC CCCCGGGGCC CTGACCCTGC TGCCCAGTGG CCTGGGGCCA 
CCGCCACCCC CACCGCCCCC CTCCCTTCAT CCCTTCGGGC CCTTCCCCCC GCCCCCTCCC 
ACCGCCACCA GCCACAACAA CACGCTACCC CACCCCCACT CCACCACTCG GGTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLGN2 ( XM_017024897.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880386.1 Homo sapiens neuroligin 2 (NLGN2), transcript variant X2, mRNA.

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CloneID	OHu87004
Clone ID Related Accession (Same CDS sequence)	XM_017024897.1
Accession Version	XM_017024897.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1971bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	neuroligin-2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTTTC TCCATGGCGG CTCCTACATG GAGGGGACCG GAAACATGTT CGATGGCTCA 
GTCCTGGCTG CCTATGGCAA CGTCATTGTA GCCACGCTCA ACTACCGTCT TGGGGTGCTC 
GGTTTTCTCA GCACCGGGGA CCAGGCTGCA AAAGGCAACT ATGGGCTCCT GGACCAGATC 
CAGGCCCTGC GCTGGCTCAG TGAAAACATC GCCCACTTTG GGGGCGACCC CGAGCGTATC 
ACCATCTTTG GTTCCGGGGC AGGGGCCTCC TGCGTCAACC TTCTGATCCT CTCCCACCAT 
TCAGAAGGGC TGTTCCAGAA GGCCATCGCC CAGAGTGGCA CCGCCATTTC CAGCTGGTCT 
GTCAACTACC AGCCGCTCAA GTACACGCGG CTGCTGGCAG CCAAGGTGGG CTGTGACCGA 
GAGGACAGCG CTGAAGCTGT GGAGTGTCTG CGCCGGAAGC CCTCCCGGGA GCTGGTGGAC 
CAGGACGTGC AGCCTGCCCG CTACCACATC GCCTTTGGGC CCGTGGTGGA TGGCGACGTG 
GTCCCCGATG ACCCTGAGAT CCTCATGCAG CAGGGAGAAT TCCTCAACTA CGACATGCTC 
ATCGGCGTCA ACCAGGGAGA GGGCCTCAAG TTCGTGGAGG ACTCTGCAGA GAGCGAGGAC 
GGTGTGTCTG CCAGCGCCTT TGACTTCACT GTCTCCAACT TTGTGGACAA CCTGTATGGC 
TACCCGGAAG GCAAGGATGT GCTTCGGGAG ACCATCAAGT TTATGTACAC AGACTGGGCC 
GACCGGGACA ATGGCGAAAT GCGCCGCAAA ACCCTGCTGG CGCTCTTTAC TGACCACCAA 
TGGGTGGCAC CAGCTGTGGC CACTGCCAAG CTGCACGCCG ACTACCAGTC TCCCGTCTAC 
TTTTACACCT TCTACCACCA CTGCCAGGCG GAGGGCCGGC CTGAGTGGGC AGATGCGGCG 
CACGGGGATG AACTGCCCTA TGTCTTTGGC GTGCCCATGG TGGGTGCCAC CGACCTCTTC 
CCCTGTAACT TCTCCAAGAA TGACGTCATG CTCAGTGCCG TGGTCATGAC CTACTGGACC 
AACTTCGCCA AGACTGGGGA CCCCAACCAG CCGGTGCCGC AGGATACCAA GTTCATCCAC 
ACCAAGCCCA ATCGCTTCGA GGAGGTGGTG TGGAGCAAAT TCAACAGCAA GGAGAAGCAG 
TATCTGCACA TAGGCCTGAA GCCACGCGTG CGTGACAACT ACCGCGCCAA CAAGGTGGCC 
TTCTGGCTGG AGCTCGTGCC CCACCTGCAC AACCTGCACA CGGAGCTCTT CACCACCACC 
ACGCGCCTGC CTCCCTACGC CACGCGCTGG CCGCCTCGTC CCCCCGCTGG CGCCCCGGGC 
ACACGCCGGC CCCCGCCGCC TGCCACCCTG CCTCCCGAGC CCGAGCCCGA GCCCGGCCCA 
AGGGCCTATG ACCGCTTCCC CGGGGACTCA CGGGACTACT CCACGGAGCT GAGCGTCACC 
GTGGCCGTGG GTGCCTCCCT CCTCTTCCTC AACATCCTGG CCTTTGCTGC CCTCTACTAC 
AAGCGGGACC GGCGGCAGGA GCTGCGGTGC AGGCGGCTTA GCCCACCTGG CGGCTCAGGC 
TCTGGCGTGC CTGGTGGGGG CCCCCTGCTC CCCGCCGCGG GCCGTGAGCT GCCACCAGAG 
GAGGAGCTGG TGTCACTGCA GCTGAAGCGG GGTGGTGGCG TCGGGGCGGA CCCTGCCGAG 
GCTCTGCGCC CTGCCTGCCC GCCCGACTAC ACCCTGGCCC TGCGCCGGGC ACCGGACGAT 
GTGCCTCTCT TGGCCCCCGG GGCCCTGACC CTGCTGCCCA GTGGCCTGGG GCCACCGCCA 
CCCCCACCGC CCCCCTCCCT TCATCCCTTC GGGCCCTTCC CCCCGCCCCC TCCCACCGCC 
ACCAGCCACA ACAACACGCT ACCCCACCCC CACTCCACCA CTCGGGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880386.1
CDS	200..2170
Translation	MLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELFTTTTRLPPYATRWPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLKRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPPPSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV

Target ORF information:

RefSeq Version	XM_017024897.1
Organism	Homo sapiens(human)
Definition	Homo sapiens neuroligin 2 (NLGN2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017024897.1

ORF Insert Sequence:

ATGCTGTTTC TCCATGGCGG CTCCTACATG GAGGGGACCG GAAACATGTT CGATGGCTCA 
GTCCTGGCTG CCTATGGCAA CGTCATTGTA GCCACGCTCA ACTACCGTCT TGGGGTGCTC 
GGTTTTCTCA GCACCGGGGA CCAGGCTGCA AAAGGCAACT ATGGGCTCCT GGACCAGATC 
CAGGCCCTGC GCTGGCTCAG TGAAAACATC GCCCACTTTG GGGGCGACCC CGAGCGTATC 
ACCATCTTTG GTTCCGGGGC AGGGGCCTCC TGCGTCAACC TTCTGATCCT CTCCCACCAT 
TCAGAAGGGC TGTTCCAGAA GGCCATCGCC CAGAGTGGCA CCGCCATTTC CAGCTGGTCT 
GTCAACTACC AGCCGCTCAA GTACACGCGG CTGCTGGCAG CCAAGGTGGG CTGTGACCGA 
GAGGACAGCG CTGAAGCTGT GGAGTGTCTG CGCCGGAAGC CCTCCCGGGA GCTGGTGGAC 
CAGGACGTGC AGCCTGCCCG CTACCACATC GCCTTTGGGC CCGTGGTGGA TGGCGACGTG 
GTCCCCGATG ACCCTGAGAT CCTCATGCAG CAGGGAGAAT TCCTCAACTA CGACATGCTC 
ATCGGCGTCA ACCAGGGAGA GGGCCTCAAG TTCGTGGAGG ACTCTGCAGA GAGCGAGGAC 
GGTGTGTCTG CCAGCGCCTT TGACTTCACT GTCTCCAACT TTGTGGACAA CCTGTATGGC 
TACCCGGAAG GCAAGGATGT GCTTCGGGAG ACCATCAAGT TTATGTACAC AGACTGGGCC 
GACCGGGACA ATGGCGAAAT GCGCCGCAAA ACCCTGCTGG CGCTCTTTAC TGACCACCAA 
TGGGTGGCAC CAGCTGTGGC CACTGCCAAG CTGCACGCCG ACTACCAGTC TCCCGTCTAC 
TTTTACACCT TCTACCACCA CTGCCAGGCG GAGGGCCGGC CTGAGTGGGC AGATGCGGCG 
CACGGGGATG AACTGCCCTA TGTCTTTGGC GTGCCCATGG TGGGTGCCAC CGACCTCTTC 
CCCTGTAACT TCTCCAAGAA TGACGTCATG CTCAGTGCCG TGGTCATGAC CTACTGGACC 
AACTTCGCCA AGACTGGGGA CCCCAACCAG CCGGTGCCGC AGGATACCAA GTTCATCCAC 
ACCAAGCCCA ATCGCTTCGA GGAGGTGGTG TGGAGCAAAT TCAACAGCAA GGAGAAGCAG 
TATCTGCACA TAGGCCTGAA GCCACGCGTG CGTGACAACT ACCGCGCCAA CAAGGTGGCC 
TTCTGGCTGG AGCTCGTGCC CCACCTGCAC AACCTGCACA CGGAGCTCTT CACCACCACC 
ACGCGCCTGC CTCCCTACGC CACGCGCTGG CCGCCTCGTC CCCCCGCTGG CGCCCCGGGC 
ACACGCCGGC CCCCGCCGCC TGCCACCCTG CCTCCCGAGC CCGAGCCCGA GCCCGGCCCA 
AGGGCCTATG ACCGCTTCCC CGGGGACTCA CGGGACTACT CCACGGAGCT GAGCGTCACC 
GTGGCCGTGG GTGCCTCCCT CCTCTTCCTC AACATCCTGG CCTTTGCTGC CCTCTACTAC 
AAGCGGGACC GGCGGCAGGA GCTGCGGTGC AGGCGGCTTA GCCCACCTGG CGGCTCAGGC 
TCTGGCGTGC CTGGTGGGGG CCCCCTGCTC CCCGCCGCGG GCCGTGAGCT GCCACCAGAG 
GAGGAGCTGG TGTCACTGCA GCTGAAGCGG GGTGGTGGCG TCGGGGCGGA CCCTGCCGAG 
GCTCTGCGCC CTGCCTGCCC GCCCGACTAC ACCCTGGCCC TGCGCCGGGC ACCGGACGAT 
GTGCCTCTCT TGGCCCCCGG GGCCCTGACC CTGCTGCCCA GTGGCCTGGG GCCACCGCCA 
CCCCCACCGC CCCCCTCCCT TCATCCCTTC GGGCCCTTCC CCCCGCCCCC TCCCACCGCC 
ACCAGCCACA ACAACACGCT ACCCCACCCC CACTCCACCA CTCGGGTATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility.
Proceedings of the National Academy of Sciences of the United States of America(2018 Jan)
Heshmati M,Aleyasin H,Menard C,Christoffel DJ,Flanigan ME,Pfau ML,Hodes GE,Lepack AE,Bicks LK,Takahashi A,Chandra R,Turecki G,Lobo MK,Maze I,Golden SA,Russo SJ

Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges.
Neuron94(6)1132-1141.e4(2017 Jun)
Gangwar SP,Zhong X,Seshadrinathan S,Chen H,Machius M,Rudenko G

Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity.
American journal of medical genetics. Part A173(1)213-216(2017 Jan)
Parente DJ,Garriga C,Baskin B,Douglas G,Cho MT,Araujo GC,Shinawi M

Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses.
eLife5(2016 11)
Nguyen QA,Horn ME,Nicoll RA

The down-regulation of neuroligin-2 and the correlative clinical significance of serum GABA over-expression in Hirschsprung's disease.
Neurochemical research39(8)1451-7(2014 Aug)
Yang H,Niu J,Wang J,Zhang F,Zhang Q,Zhang W,Li A

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NLGN2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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