XPO5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	XPO5
Entrez Gene ID	57510
Full Name	exportin 5
Synonyms	exp5
General protein information	Preferred Names exportin 5 Names exportin-5 ran-binding protein 21
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.1
Summary	This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process. [provided by RefSeq, Aug 2011].
Disorder MIM:	607845

mRNA and Protein(s)

mRNA	Protein	Name
NM_020750.2	NP_065801.1	exportin-5
NM_020750.3	NP_065801.1	exportin-5

Pathways from BioSystems

Homologies

Bos taurus (cattle)	XPO5	XP_002697347.1
Rattus norvegicus (Norway rat)	Xpo5	NP_001102259.2
Gallus gallus (chicken)	XPO5	NP_001264581.1
Danio rerio (zebrafish)	xpo5	XP_001921422.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011888	XP_320637.3
Canis lupus familiaris (dog)	XPO5	XP_005627452.1
Mus musculus (house mouse)	Xpo5	NP_082474.1
Oryza sativa (rice)	Os01g0363900	NP_001043034.1
Homo sapiens (human)	XPO5	NP_065801.1
	XPO5	XP_002803804.1
Arabidopsis thaliana (thale cress)	HST	NP_187155.2
Xenopus tropicalis (tropical clawed frog)	xpo5	NP_989112.2
Pan troglodytes (chimpanzee)	XPO5	XP_003311360.1
Drosophila melanogaster (fruit fly)	Ranbp21	NP_608339.2

Gene Ontology
Bibliography

Related articles in PubMed

Association of microRNA-related gene XPO5 rs11077 polymorphism with susceptibility to thyroid cancer.
Wen J, Gao Q, Wang N, Zhang W, Cao K, Zhang Q, Chen S, Shi L
Medicine96(14)e6351(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SNP rs11077 influences the expression of XPO5, and this SNP could also be a potential biomarker for the diagnosis of thyroid cancer, especially in Chinese population
Title: Association of microRNA-related gene XPO5 rs11077 polymorphism with susceptibility to thyroid cancer.

one SNP in XPO5 extron (rs2257082) was significantly associated with lead-poisoning; there were no significant association between the other six SNPs and the blood lead levels; polymorphism rs2257082 could be used to distinguish lead-resistant and lead-susceptible populations
Title: Association between Polymorphism of Exportin-5 and Susceptibility to Lead Poisoning in a Chinese Population.

findings suggest that XPO5 functions as a potential tumor suppressor in the development and progression of HCC as well as a promising molecular target for HCC therapy
Title: Downregulation and tumor-suppressive role of XPO5 in hepatocellular carcinoma.

NUP93 and exportin 5 interact with the signaling protein SMAD4 and that NUP93 mutations abrogated interaction with SMAD4
Title: Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome.

XPO5 role in microRNA biogenesis
Title: Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.

The following XPO5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XPO5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17570	NM_020750.3 Latest version!	Homo sapiens exportin 5 (XPO5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
View Old Accession Versions >>
OHu17570	NM_020750.2	Homo sapiens exportin 5 (XPO5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XPO5 ( NM_020750.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_065801.1 Homo sapiens exportin 5 (XPO5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17570
Clone ID Related Accession (Same CDS sequence)	NM_020750.2 , NM_020750.3
Accession Version	NM_020750.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	exportin-5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB068849.1, AF298880.1, AB033117.2 and BF108994.1. This sequence is a reference standard in the RefSeqGene project. On Jan 22, 2009 this sequence version replaced NM_020750.1. Transcript Variant: This variant (1) represents the protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.105282.1, AB033117.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGATGG ATCAAGTAAA CGCGCTGTGC GAGCAGCTGG TGAAAGCGGT GACGGTCATG 
ATGGACCCCA ACTCCACCCA GCGCTACCGG CTGGAAGCCC TCAAGTTTTG TGAGGAGTTT 
AAAGAAAAGT GTCCTATCTG TGTCCCCTGT GGCTTGAGGT TGGCTGAGAA AACACAAGTT 
GCCATCGTCA GACATTTTGG CCTTCAGATC CTGGAACACG TTGTCAAGTT TCGGTGGAAC 
GGCATGTCTC GATTGGAGAA GGTGTATCTG AAGAACAGTG TCATGGAGCT GATTGCAAAT 
GGAACATTGA ACATTTTGGA AGAGGAGAAC CATATTAAAG ATGCTCTGTC TCGAATTGTA 
GTGGAAATGA TCAAGCGAGA GTGGCCACAG CATTGGCCTG ACATGCTAAT AGAATTGGAC 
ACTCTTTCCA AACAAGGGGA AACACAGACA GAATTGGTGA TGTTTATCCT TTTGCGACTG 
GCAGAGGATG TAGTGACTTT TCAGACACTT CCCCCTCAAA GAAGAAGGGA CATCCAGCAA 
ACATTAACCC AGAACATGGA AAGGATCTTC AGTTTTCTGC TTAACACACT TCAAGAAAAT 
GTAAACAAGT ATCAGCAAGT GAAGACAGAT ACTTCTCAGG AGTCAAAGGC GCAAGCAAAC 
TGTCGAGTAG GAGTTGCAGC ACTGAATACT CTAGCAGGCT ATATTGACTG GGTGTCTATG 
AGTCACATCA CTGCTGAAAA CTGTAAACTC CTGGAGATAC TGTGTTTGCT GTTGAATGAA 
CAGGAACTTC AGTTGGGAGC CGCTGAGTGT CTTCTCATTG CAGTCAGCAG AAAAGGCAAG 
TTGGAAGACC GGAAGCCCTT GATGGTCTTA TTTGGAGATG TTGCCATGCA TTATATACTC 
TCCGCCGCAC AGACTGCTGA TGGAGGAGGT TTGGTAGAAA AACACTACGT CTTTCTGAAG 
AGGCTCTGTC AGGTGTTGTG TGCGCTGGGC AATCAGCTGT GTGCATTGCT GGGTGCAGAT 
TCTGATGTAG AAACACCATC AAACTTTGGA AAATACCTGG AATCTTTTCT TGCTTTCACA 
ACCCATCCAA GTCAGTTTCT ACGCTCTTCA ACTCAGATGA CTTGGGGAGC CCTCTTCAGG 
CATGAAATCC TGTCCCGTGA TCCTTTGCTA TTAGCAATAA TACCAAAATA TCTTCGTGCT 
TCCATGACTA ACTTGGTCAA GATGGGCTTT CCTTCTAAAA CAGACAGCCC TAGCTGTGAA 
TATTCTCGGT TTGATTTTGA TAGCGATGAG GACTTCAATG CTTTCTTCAA CTCCTCCCGA 
GCACAACAAG GAGAGGTGAT GAGGTTGGCA TGTCGTTTGG ATCCCAAAAC TAGCTTCCAG 
ATGGCTGGGG AGTGGCTAAA GTATCAACTA TCAACTTTTC TTGATGCTGG TTCTGTGAAT 
TCTTGTTCTG CAGTTGGAAC TGGAGAAGGA AGCCTCTGTT CCGTCTTCTC ACCTTCATTC 
GTGCAGTGGG AAGCCATGAC TCTTTTTTTG GAAAGTGTTA TCACCCAGAT GTTTCGAACA 
CTAAATAGAG AAGAAATTCC TGTTAATGAT GGAATAGAGC TATTGCAGAT GGTTCTGAAC 
TTTGATACCA AGGATCCCCT CATCCTGTCC TGCGTCCTTA CTAATGTCTC TGCACTCTTT 
CCATTTGTCA CCTACAGACC AGAGTTCCTG CCCCAGGTCT TCTCTAAGCT ATTTTCATCT 
GTCACTTTTG AAACTGTTGA AGAAAGTAAG GCCCCCAGAA CCCGGGCAGT GAGGAATGTG 
AGGAGGCATG CTTGTTCCTC CATCATCAAG ATGTGTCGTG ACTACCCCCA GCTTGTGCTG 
CCCAATTTTG ACATGCTTTA TAACCATGTG AAGCAACTCC TCTCCAATGA GCTACTCCTG 
ACACAAATGG AGAAGTGTGC CCTCATGGAA GCCCTGGTTC TCATTAGCAA CCAATTTAAG 
AACTACGAGC GTCAGAAGGT GTTCCTAGAG GAGCTGATGG CACCAGTGGC CAGCATCTGG 
CTTTCTCAAG ACATGCACAG AGTGCTGTCA GATGTTGATG CTTTCATTGC GTATGTGGGT 
ACAGATCAGA AGAGCTGTGA CCCAGGCCTG GAGGATCCGT GTGGCTTAAA CCGTGCACGA 
ATGAGCTTTT GTGTATACAG CATTCTGGGT GTGGTGAAAC GAACTTGCTG GCCCACTGAC 
CTAGAAGAGG CCAAAGCTGG GGGATTTGTG GTGGGTTATA CATCCAGTGG AAATCCAATC 
TTCCGTAACC CCTGCACAGA GCAGATTCTG AAACTTCTTG ACAATTTGCT TGCGCTTATA 
AGAACCCACA ATACATTATA TGCACCAGAA ATGCTAGCCA AAATGGCAGA GCCTTTCACC 
AAGGCTCTGG ATATGCTTGA CGCGGAAAAA TCTGCTATAT TAGGATTACC TCAACCTCTC 
TTGGAACTCA ATGACTCTCC TGTCTTCAAA ACCGTCTTGG AAAGAATGCA GCGTTTCTTC 
TCTACCCTCT ATGAAAACTG TTTTCATATC CTAGGGAAGG CAGGCCCTTC CATGCAGCAA 
GACTTCTATA CTGTGGAGGA CCTTGCTACC CAGCTTCTCA GCTCAGCCTT TGTCAACTTG 
AACAATATTC CTGACTACCG ACTCAGACCC ATGCTTCGTG TCTTTGTAAA GCCTCTGGTG 
CTCTTCTGTC CCCCAGAGCA CTATGAAGCC CTGGTATCCC CCATCCTCGG ACCTCTTTTC 
ACCTACCTCC ATATGAGGCT TTCTCAGAAA TGGCAAGTTA TCAACCAAAG GAGCCTGCTG 
TGTGGAGAAG ATGAGGCTGC AGATGAAAAC CCAGAGTCTC AAGAGATGCT GGAGGAGCAA 
CTGGTGAGGA TGTTAACCCG AGAAGTCATG GACCTAATCA CGGTTTGCTG TGTTTCAAAG 
AAGGGTGCTG ACCACAGTAG TGCTCCCCCA GCAGATGGAG ACGATGAAGA AATGATGGCC 
ACAGAGGTCA CCCCCTCAGC TATGGCAGAG CTTACAGACC TGGGCAAATG TCTGATGAAG 
CATGAGGATG TTTGTACAGC GCTATTAATT ACAGCCTTCA ATTCCCTGGC CTGGAAAGAT 
ACTCTGTCCT GCCAGAGGAC AACCTCACAG CTCTGCTGGC CTCTCCTCAA ACAAGTGCTG 
TCAGGGACAC TGCTCGCAGA TGCAGTTACG TGGCTTTTCA CCAGTGTGCT GAAAGGCTTA 
CAGATGCACG GGCAGCACGA CGGGTGCATG GCTTCCCTGG TCCATCTGGC CTTCCAGATA 
TACGAGGCAC TGCGCCCCAG GTACCTGGAG ATAAGAGCTG TAATGGAGCA AATCCCTGAA 
ATACAGAAGG ACTCACTGGA CCAGTTTGAC TGCAAGCTTT TAAACCCCTC CCTGCAGAAA 
GTGGCTGACA AGCGCCGAAA GGACCAATTC AAACGCCTCA TTGCTGGTTG CATTGGGAAA 
CCCTTGGGAG AGCAGTTCCG AAAAGAAGTT CACATTAAGA ATCTTCCCTC ACTTTTCAAA 
AAAACAAAGC CAATGCTGGA GACGGAGGTG CTGGACAATG ATGGGGGTGG CCTGGCCACC 
ATCTTTGAAC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065801.1
CDS	212..3826
Translation	MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFTTHPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLNFDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRARMSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFFSTLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLVLFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDLITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMKHEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQKVADKRRKDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLATIFEP

Target ORF information:

RefSeq Version	NM_020750.2
Organism	Homo sapiens(human)
Definition	Homo sapiens exportin 5 (XPO5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020750.2

ORF Insert Sequence:

ATGGCGATGG ATCAAGTAAA CGCGCTGTGC GAGCAGCTGG TGAAAGCGGT GACGGTCATG 
ATGGACCCCA ACTCCACCCA GCGCTACCGG CTGGAAGCCC TCAAGTTTTG TGAGGAGTTT 
AAAGAAAAGT GTCCTATCTG TGTCCCCTGT GGCTTGAGGT TGGCTGAGAA AACACAAGTT 
GCCATCGTCA GACATTTTGG CCTTCAGATC CTGGAACACG TTGTCAAGTT TCGGTGGAAC 
GGCATGTCTC GATTGGAGAA GGTGTATCTG AAGAACAGTG TCATGGAGCT GATTGCAAAT 
GGAACATTGA ACATTTTGGA AGAGGAGAAC CATATTAAAG ATGCTCTGTC TCGAATTGTA 
GTGGAAATGA TCAAGCGAGA GTGGCCACAG CATTGGCCTG ACATGCTAAT AGAATTGGAC 
ACTCTTTCCA AACAAGGGGA AACACAGACA GAATTGGTGA TGTTTATCCT TTTGCGACTG 
GCAGAGGATG TAGTGACTTT TCAGACACTT CCCCCTCAAA GAAGAAGGGA CATCCAGCAA 
ACATTAACCC AGAACATGGA AAGGATCTTC AGTTTTCTGC TTAACACACT TCAAGAAAAT 
GTAAACAAGT ATCAGCAAGT GAAGACAGAT ACTTCTCAGG AGTCAAAGGC GCAAGCAAAC 
TGTCGAGTAG GAGTTGCAGC ACTGAATACT CTAGCAGGCT ATATTGACTG GGTGTCTATG 
AGTCACATCA CTGCTGAAAA CTGTAAACTC CTGGAGATAC TGTGTTTGCT GTTGAATGAA 
CAGGAACTTC AGTTGGGAGC CGCTGAGTGT CTTCTCATTG CAGTCAGCAG AAAAGGCAAG 
TTGGAAGACC GGAAGCCCTT GATGGTCTTA TTTGGAGATG TTGCCATGCA TTATATACTC 
TCCGCCGCAC AGACTGCTGA TGGAGGAGGT TTGGTAGAAA AACACTACGT CTTTCTGAAG 
AGGCTCTGTC AGGTGTTGTG TGCGCTGGGC AATCAGCTGT GTGCATTGCT GGGTGCAGAT 
TCTGATGTAG AAACACCATC AAACTTTGGA AAATACCTGG AATCTTTTCT TGCTTTCACA 
ACCCATCCAA GTCAGTTTCT ACGCTCTTCA ACTCAGATGA CTTGGGGAGC CCTCTTCAGG 
CATGAAATCC TGTCCCGTGA TCCTTTGCTA TTAGCAATAA TACCAAAATA TCTTCGTGCT 
TCCATGACTA ACTTGGTCAA GATGGGCTTT CCTTCTAAAA CAGACAGCCC TAGCTGTGAA 
TATTCTCGGT TTGATTTTGA TAGCGATGAG GACTTCAATG CTTTCTTCAA CTCCTCCCGA 
GCACAACAAG GAGAGGTGAT GAGGTTGGCA TGTCGTTTGG ATCCCAAAAC TAGCTTCCAG 
ATGGCTGGGG AGTGGCTAAA GTATCAACTA TCAACTTTTC TTGATGCTGG TTCTGTGAAT 
TCTTGTTCTG CAGTTGGAAC TGGAGAAGGA AGCCTCTGTT CCGTCTTCTC ACCTTCATTC 
GTGCAGTGGG AAGCCATGAC TCTTTTTTTG GAAAGTGTTA TCACCCAGAT GTTTCGAACA 
CTAAATAGAG AAGAAATTCC TGTTAATGAT GGAATAGAGC TATTGCAGAT GGTTCTGAAC 
TTTGATACCA AGGATCCCCT CATCCTGTCC TGCGTCCTTA CTAATGTCTC TGCACTCTTT 
CCATTTGTCA CCTACAGACC AGAGTTCCTG CCCCAGGTCT TCTCTAAGCT ATTTTCATCT 
GTCACTTTTG AAACTGTTGA AGAAAGTAAG GCCCCCAGAA CCCGGGCAGT GAGGAATGTG 
AGGAGGCATG CTTGTTCCTC CATCATCAAG ATGTGTCGTG ACTACCCCCA GCTTGTGCTG 
CCCAATTTTG ACATGCTTTA TAACCATGTG AAGCAACTCC TCTCCAATGA GCTACTCCTG 
ACACAAATGG AGAAGTGTGC CCTCATGGAA GCCCTGGTTC TCATTAGCAA CCAATTTAAG 
AACTACGAGC GTCAGAAGGT GTTCCTAGAG GAGCTGATGG CACCAGTGGC CAGCATCTGG 
CTTTCTCAAG ACATGCACAG AGTGCTGTCA GATGTTGATG CTTTCATTGC GTATGTGGGT 
ACAGATCAGA AGAGCTGTGA CCCAGGCCTG GAGGATCCGT GTGGCTTAAA CCGTGCACGA 
ATGAGCTTTT GTGTATACAG CATTCTGGGT GTGGTGAAAC GAACTTGCTG GCCCACTGAC 
CTAGAAGAGG CCAAAGCTGG GGGATTTGTG GTGGGTTATA CATCCAGTGG AAATCCAATC 
TTCCGTAACC CCTGCACAGA GCAGATTCTG AAACTTCTTG ACAATTTGCT TGCGCTTATA 
AGAACCCACA ATACATTATA TGCACCAGAA ATGCTAGCCA AAATGGCAGA GCCTTTCACC 
AAGGCTCTGG ATATGCTTGA CGCGGAAAAA TCTGCTATAT TAGGATTACC TCAACCTCTC 
TTGGAACTCA ATGACTCTCC TGTCTTCAAA ACCGTCTTGG AAAGAATGCA GCGTTTCTTC 
TCTACCCTCT ATGAAAACTG TTTTCATATC CTAGGGAAGG CAGGCCCTTC CATGCAGCAA 
GACTTCTATA CTGTGGAGGA CCTTGCTACC CAGCTTCTCA GCTCAGCCTT TGTCAACTTG 
AACAATATTC CTGACTACCG ACTCAGACCC ATGCTTCGTG TCTTTGTAAA GCCTCTGGTG 
CTCTTCTGTC CCCCAGAGCA CTATGAAGCC CTGGTATCCC CCATCCTCGG ACCTCTTTTC 
ACCTACCTCC ATATGAGGCT TTCTCAGAAA TGGCAAGTTA TCAACCAAAG GAGCCTGCTG 
TGTGGAGAAG ATGAGGCTGC AGATGAAAAC CCAGAGTCTC AAGAGATGCT GGAGGAGCAA 
CTGGTGAGGA TGTTAACCCG AGAAGTCATG GACCTAATCA CGGTTTGCTG TGTTTCAAAG 
AAGGGTGCTG ACCACAGTAG TGCTCCCCCA GCAGATGGAG ACGATGAAGA AATGATGGCC 
ACAGAGGTCA CCCCCTCAGC TATGGCAGAG CTTACAGACC TGGGCAAATG TCTGATGAAG 
CATGAGGATG TTTGTACAGC GCTATTAATT ACAGCCTTCA ATTCCCTGGC CTGGAAAGAT 
ACTCTGTCCT GCCAGAGGAC AACCTCACAG CTCTGCTGGC CTCTCCTCAA ACAAGTGCTG 
TCAGGGACAC TGCTCGCAGA TGCAGTTACG TGGCTTTTCA CCAGTGTGCT GAAAGGCTTA 
CAGATGCACG GGCAGCACGA CGGGTGCATG GCTTCCCTGG TCCATCTGGC CTTCCAGATA 
TACGAGGCAC TGCGCCCCAG GTACCTGGAG ATAAGAGCTG TAATGGAGCA AATCCCTGAA 
ATACAGAAGG ACTCACTGGA CCAGTTTGAC TGCAAGCTTT TAAACCCCTC CCTGCAGAAA 
GTGGCTGACA AGCGCCGAAA GGACCAATTC AAACGCCTCA TTGCTGGTTG CATTGGGAAA 
CCCTTGGGAG AGCAGTTCCG AAAAGAAGTT CACATTAAGA ATCTTCCCTC ACTTTTCAAA 
AAAACAAAGC CAATGCTGGA GACGGAGGTG CTGGACAATG ATGGGGGTGG CCTGGCCACC 
ATCTTTGAAC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XPO5 ( NM_020750.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065801.1 Homo sapiens exportin 5 (XPO5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17570
Clone ID Related Accession (Same CDS sequence)	NM_020750.2 , NM_020750.3
Accession Version	NM_020750.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3615bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	exportin-5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB068849.1, AF298880.1, AB033117.2 and BF108994.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_020750.2. Transcript Variant: This variant (1) represents the protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF298880.1, SRR1803612.105282.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265351.12/ ENSP00000265351.7 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGATGG ATCAAGTAAA CGCGCTGTGC GAGCAGCTGG TGAAAGCGGT GACGGTCATG 
ATGGACCCCA ACTCCACCCA GCGCTACCGG CTGGAAGCCC TCAAGTTTTG TGAGGAGTTT 
AAAGAAAAGT GTCCTATCTG TGTCCCCTGT GGCTTGAGGT TGGCTGAGAA AACACAAGTT 
GCCATCGTCA GACATTTTGG CCTTCAGATC CTGGAACACG TTGTCAAGTT TCGGTGGAAC 
GGCATGTCTC GATTGGAGAA GGTGTATCTG AAGAACAGTG TCATGGAGCT GATTGCAAAT 
GGAACATTGA ACATTTTGGA AGAGGAGAAC CATATTAAAG ATGCTCTGTC TCGAATTGTA 
GTGGAAATGA TCAAGCGAGA GTGGCCACAG CATTGGCCTG ACATGCTAAT AGAATTGGAC 
ACTCTTTCCA AACAAGGGGA AACACAGACA GAATTGGTGA TGTTTATCCT TTTGCGACTG 
GCAGAGGATG TAGTGACTTT TCAGACACTT CCCCCTCAAA GAAGAAGGGA CATCCAGCAA 
ACATTAACCC AGAACATGGA AAGGATCTTC AGTTTTCTGC TTAACACACT TCAAGAAAAT 
GTAAACAAGT ATCAGCAAGT GAAGACAGAT ACTTCTCAGG AGTCAAAGGC GCAAGCAAAC 
TGTCGAGTAG GAGTTGCAGC ACTGAATACT CTAGCAGGCT ATATTGACTG GGTGTCTATG 
AGTCACATCA CTGCTGAAAA CTGTAAACTC CTGGAGATAC TGTGTTTGCT GTTGAATGAA 
CAGGAACTTC AGTTGGGAGC CGCTGAGTGT CTTCTCATTG CAGTCAGCAG AAAAGGCAAG 
TTGGAAGACC GGAAGCCCTT GATGGTCTTA TTTGGAGATG TTGCCATGCA TTATATACTC 
TCCGCCGCAC AGACTGCTGA TGGAGGAGGT TTGGTAGAAA AACACTACGT CTTTCTGAAG 
AGGCTCTGTC AGGTGTTGTG TGCGCTGGGC AATCAGCTGT GTGCATTGCT GGGTGCAGAT 
TCTGATGTAG AAACACCATC AAACTTTGGA AAATACCTGG AATCTTTTCT TGCTTTCACA 
ACCCATCCAA GTCAGTTTCT ACGCTCTTCA ACTCAGATGA CTTGGGGAGC CCTCTTCAGG 
CATGAAATCC TGTCCCGTGA TCCTTTGCTA TTAGCAATAA TACCAAAATA TCTTCGTGCT 
TCCATGACTA ACTTGGTCAA GATGGGCTTT CCTTCTAAAA CAGACAGCCC TAGCTGTGAA 
TATTCTCGGT TTGATTTTGA TAGCGATGAG GACTTCAATG CTTTCTTCAA CTCCTCCCGA 
GCACAACAAG GAGAGGTGAT GAGGTTGGCA TGTCGTTTGG ATCCCAAAAC TAGCTTCCAG 
ATGGCTGGGG AGTGGCTAAA GTATCAACTA TCAACTTTTC TTGATGCTGG TTCTGTGAAT 
TCTTGTTCTG CAGTTGGAAC TGGAGAAGGA AGCCTCTGTT CCGTCTTCTC ACCTTCATTC 
GTGCAGTGGG AAGCCATGAC TCTTTTTTTG GAAAGTGTTA TCACCCAGAT GTTTCGAACA 
CTAAATAGAG AAGAAATTCC TGTTAATGAT GGAATAGAGC TATTGCAGAT GGTTCTGAAC 
TTTGATACCA AGGATCCCCT CATCCTGTCC TGCGTCCTTA CTAATGTCTC TGCACTCTTT 
CCATTTGTCA CCTACAGACC AGAGTTCCTG CCCCAGGTCT TCTCTAAGCT ATTTTCATCT 
GTCACTTTTG AAACTGTTGA AGAAAGTAAG GCCCCCAGAA CCCGGGCAGT GAGGAATGTG 
AGGAGGCATG CTTGTTCCTC CATCATCAAG ATGTGTCGTG ACTACCCCCA GCTTGTGCTG 
CCCAATTTTG ACATGCTTTA TAACCATGTG AAGCAACTCC TCTCCAATGA GCTACTCCTG 
ACACAAATGG AGAAGTGTGC CCTCATGGAA GCCCTGGTTC TCATTAGCAA CCAATTTAAG 
AACTACGAGC GTCAGAAGGT GTTCCTAGAG GAGCTGATGG CACCAGTGGC CAGCATCTGG 
CTTTCTCAAG ACATGCACAG AGTGCTGTCA GATGTTGATG CTTTCATTGC GTATGTGGGT 
ACAGATCAGA AGAGCTGTGA CCCAGGCCTG GAGGATCCGT GTGGCTTAAA CCGTGCACGA 
ATGAGCTTTT GTGTATACAG CATTCTGGGT GTGGTGAAAC GAACTTGCTG GCCCACTGAC 
CTAGAAGAGG CCAAAGCTGG GGGATTTGTG GTGGGTTATA CATCCAGTGG AAATCCAATC 
TTCCGTAACC CCTGCACAGA GCAGATTCTG AAACTTCTTG ACAATTTGCT TGCGCTTATA 
AGAACCCACA ATACATTATA TGCACCAGAA ATGCTAGCCA AAATGGCAGA GCCTTTCACC 
AAGGCTCTGG ATATGCTTGA CGCGGAAAAA TCTGCTATAT TAGGATTACC TCAACCTCTC 
TTGGAACTCA ATGACTCTCC TGTCTTCAAA ACCGTCTTGG AAAGAATGCA GCGTTTCTTC 
TCTACCCTCT ATGAAAACTG TTTTCATATC CTAGGGAAGG CAGGCCCTTC CATGCAGCAA 
GACTTCTATA CTGTGGAGGA CCTTGCTACC CAGCTTCTCA GCTCAGCCTT TGTCAACTTG 
AACAATATTC CTGACTACCG ACTCAGACCC ATGCTTCGTG TCTTTGTAAA GCCTCTGGTG 
CTCTTCTGTC CCCCAGAGCA CTATGAAGCC CTGGTATCCC CCATCCTCGG ACCTCTTTTC 
ACCTACCTCC ATATGAGGCT TTCTCAGAAA TGGCAAGTTA TCAACCAAAG GAGCCTGCTG 
TGTGGAGAAG ATGAGGCTGC AGATGAAAAC CCAGAGTCTC AAGAGATGCT GGAGGAGCAA 
CTGGTGAGGA TGTTAACCCG AGAAGTCATG GACCTAATCA CGGTTTGCTG TGTTTCAAAG 
AAGGGTGCTG ACCACAGTAG TGCTCCCCCA GCAGATGGAG ACGATGAAGA AATGATGGCC 
ACAGAGGTCA CCCCCTCAGC TATGGCAGAG CTTACAGACC TGGGCAAATG TCTGATGAAG 
CATGAGGATG TTTGTACAGC GCTATTAATT ACAGCCTTCA ATTCCCTGGC CTGGAAAGAT 
ACTCTGTCCT GCCAGAGGAC AACCTCACAG CTCTGCTGGC CTCTCCTCAA ACAAGTGCTG 
TCAGGGACAC TGCTCGCAGA TGCAGTTACG TGGCTTTTCA CCAGTGTGCT GAAAGGCTTA 
CAGATGCACG GGCAGCACGA CGGGTGCATG GCTTCCCTGG TCCATCTGGC CTTCCAGATA 
TACGAGGCAC TGCGCCCCAG GTACCTGGAG ATAAGAGCTG TAATGGAGCA AATCCCTGAA 
ATACAGAAGG ACTCACTGGA CCAGTTTGAC TGCAAGCTTT TAAACCCCTC CCTGCAGAAA 
GTGGCTGACA AGCGCCGAAA GGACCAATTC AAACGCCTCA TTGCTGGTTG CATTGGGAAA 
CCCTTGGGAG AGCAGTTCCG AAAAGAAGTT CACATTAAGA ATCTTCCCTC ACTTTTCAAA 
AAAACAAAGC CAATGCTGGA GACGGAGGTG CTGGACAATG ATGGGGGTGG CCTGGCCACC 
ATCTTTGAAC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065801.1
CDS	175..3789
Translation	MAMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAIVRHFGLQILEHVVKFRWNGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDALSRIVVEMIKREWPQHWPDMLIELDTLSKQGETQTELVMFILLRLAEDVVTFQTLPPQRRRDIQQTLTQNMERIFSFLLNTLQENVNKYQQVKTDTSQESKAQANCRVGVAALNTLAGYIDWVSMSHITAENCKLLEILCLLLNEQELQLGAAECLLIAVSRKGKLEDRKPLMVLFGDVAMHYILSAAQTADGGGLVEKHYVFLKRLCQVLCALGNQLCALLGADSDVETPSNFGKYLESFLAFTTHPSQFLRSSTQMTWGALFRHEILSRDPLLLAIIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQQGEVMRLACRLDPKTSFQMAGEWLKYQLSTFLDAGSVNSCSAVGTGEGSLCSVFSPSFVQWEAMTLFLESVITQMFRTLNREEIPVNDGIELLQMVLNFDTKDPLILSCVLTNVSALFPFVTYRPEFLPQVFSKLFSSVTFETVEESKAPRTRAVRNVRRHACSSIIKMCRDYPQLVLPNFDMLYNHVKQLLSNELLLTQMEKCALMEALVLISNQFKNYERQKVFLEELMAPVASIWLSQDMHRVLSDVDAFIAYVGTDQKSCDPGLEDPCGLNRARMSFCVYSILGVVKRTCWPTDLEEAKAGGFVVGYTSSGNPIFRNPCTEQILKLLDNLLALIRTHNTLYAPEMLAKMAEPFTKALDMLDAEKSAILGLPQPLLELNDSPVFKTVLERMQRFFSTLYENCFHILGKAGPSMQQDFYTVEDLATQLLSSAFVNLNNIPDYRLRPMLRVFVKPLVLFCPPEHYEALVSPILGPLFTYLHMRLSQKWQVINQRSLLCGEDEAADENPESQEMLEEQLVRMLTREVMDLITVCCVSKKGADHSSAPPADGDDEEMMATEVTPSAMAELTDLGKCLMKHEDVCTALLITAFNSLAWKDTLSCQRTTSQLCWPLLKQVLSGTLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEIQKDSLDQFDCKLLNPSLQKVADKRRKDQFKRLIAGCIGKPLGEQFRKEVHIKNLPSLFKKTKPMLETEVLDNDGGGLATIFEP

Target ORF information:

RefSeq Version	NM_020750.3
Organism	Homo sapiens(human)
Definition	Homo sapiens exportin 5 (XPO5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020750.3

ORF Insert Sequence:

ATGGCGATGG ATCAAGTAAA CGCGCTGTGC GAGCAGCTGG TGAAAGCGGT GACGGTCATG 
ATGGACCCCA ACTCCACCCA GCGCTACCGG CTGGAAGCCC TCAAGTTTTG TGAGGAGTTT 
AAAGAAAAGT GTCCTATCTG TGTCCCCTGT GGCTTGAGGT TGGCTGAGAA AACACAAGTT 
GCCATCGTCA GACATTTTGG CCTTCAGATC CTGGAACACG TTGTCAAGTT TCGGTGGAAC 
GGCATGTCTC GATTGGAGAA GGTGTATCTG AAGAACAGTG TCATGGAGCT GATTGCAAAT 
GGAACATTGA ACATTTTGGA AGAGGAGAAC CATATTAAAG ATGCTCTGTC TCGAATTGTA 
GTGGAAATGA TCAAGCGAGA GTGGCCACAG CATTGGCCTG ACATGCTAAT AGAATTGGAC 
ACTCTTTCCA AACAAGGGGA AACACAGACA GAATTGGTGA TGTTTATCCT TTTGCGACTG 
GCAGAGGATG TAGTGACTTT TCAGACACTT CCCCCTCAAA GAAGAAGGGA CATCCAGCAA 
ACATTAACCC AGAACATGGA AAGGATCTTC AGTTTTCTGC TTAACACACT TCAAGAAAAT 
GTAAACAAGT ATCAGCAAGT GAAGACAGAT ACTTCTCAGG AGTCAAAGGC GCAAGCAAAC 
TGTCGAGTAG GAGTTGCAGC ACTGAATACT CTAGCAGGCT ATATTGACTG GGTGTCTATG 
AGTCACATCA CTGCTGAAAA CTGTAAACTC CTGGAGATAC TGTGTTTGCT GTTGAATGAA 
CAGGAACTTC AGTTGGGAGC CGCTGAGTGT CTTCTCATTG CAGTCAGCAG AAAAGGCAAG 
TTGGAAGACC GGAAGCCCTT GATGGTCTTA TTTGGAGATG TTGCCATGCA TTATATACTC 
TCCGCCGCAC AGACTGCTGA TGGAGGAGGT TTGGTAGAAA AACACTACGT CTTTCTGAAG 
AGGCTCTGTC AGGTGTTGTG TGCGCTGGGC AATCAGCTGT GTGCATTGCT GGGTGCAGAT 
TCTGATGTAG AAACACCATC AAACTTTGGA AAATACCTGG AATCTTTTCT TGCTTTCACA 
ACCCATCCAA GTCAGTTTCT ACGCTCTTCA ACTCAGATGA CTTGGGGAGC CCTCTTCAGG 
CATGAAATCC TGTCCCGTGA TCCTTTGCTA TTAGCAATAA TACCAAAATA TCTTCGTGCT 
TCCATGACTA ACTTGGTCAA GATGGGCTTT CCTTCTAAAA CAGACAGCCC TAGCTGTGAA 
TATTCTCGGT TTGATTTTGA TAGCGATGAG GACTTCAATG CTTTCTTCAA CTCCTCCCGA 
GCACAACAAG GAGAGGTGAT GAGGTTGGCA TGTCGTTTGG ATCCCAAAAC TAGCTTCCAG 
ATGGCTGGGG AGTGGCTAAA GTATCAACTA TCAACTTTTC TTGATGCTGG TTCTGTGAAT 
TCTTGTTCTG CAGTTGGAAC TGGAGAAGGA AGCCTCTGTT CCGTCTTCTC ACCTTCATTC 
GTGCAGTGGG AAGCCATGAC TCTTTTTTTG GAAAGTGTTA TCACCCAGAT GTTTCGAACA 
CTAAATAGAG AAGAAATTCC TGTTAATGAT GGAATAGAGC TATTGCAGAT GGTTCTGAAC 
TTTGATACCA AGGATCCCCT CATCCTGTCC TGCGTCCTTA CTAATGTCTC TGCACTCTTT 
CCATTTGTCA CCTACAGACC AGAGTTCCTG CCCCAGGTCT TCTCTAAGCT ATTTTCATCT 
GTCACTTTTG AAACTGTTGA AGAAAGTAAG GCCCCCAGAA CCCGGGCAGT GAGGAATGTG 
AGGAGGCATG CTTGTTCCTC CATCATCAAG ATGTGTCGTG ACTACCCCCA GCTTGTGCTG 
CCCAATTTTG ACATGCTTTA TAACCATGTG AAGCAACTCC TCTCCAATGA GCTACTCCTG 
ACACAAATGG AGAAGTGTGC CCTCATGGAA GCCCTGGTTC TCATTAGCAA CCAATTTAAG 
AACTACGAGC GTCAGAAGGT GTTCCTAGAG GAGCTGATGG CACCAGTGGC CAGCATCTGG 
CTTTCTCAAG ACATGCACAG AGTGCTGTCA GATGTTGATG CTTTCATTGC GTATGTGGGT 
ACAGATCAGA AGAGCTGTGA CCCAGGCCTG GAGGATCCGT GTGGCTTAAA CCGTGCACGA 
ATGAGCTTTT GTGTATACAG CATTCTGGGT GTGGTGAAAC GAACTTGCTG GCCCACTGAC 
CTAGAAGAGG CCAAAGCTGG GGGATTTGTG GTGGGTTATA CATCCAGTGG AAATCCAATC 
TTCCGTAACC CCTGCACAGA GCAGATTCTG AAACTTCTTG ACAATTTGCT TGCGCTTATA 
AGAACCCACA ATACATTATA TGCACCAGAA ATGCTAGCCA AAATGGCAGA GCCTTTCACC 
AAGGCTCTGG ATATGCTTGA CGCGGAAAAA TCTGCTATAT TAGGATTACC TCAACCTCTC 
TTGGAACTCA ATGACTCTCC TGTCTTCAAA ACCGTCTTGG AAAGAATGCA GCGTTTCTTC 
TCTACCCTCT ATGAAAACTG TTTTCATATC CTAGGGAAGG CAGGCCCTTC CATGCAGCAA 
GACTTCTATA CTGTGGAGGA CCTTGCTACC CAGCTTCTCA GCTCAGCCTT TGTCAACTTG 
AACAATATTC CTGACTACCG ACTCAGACCC ATGCTTCGTG TCTTTGTAAA GCCTCTGGTG 
CTCTTCTGTC CCCCAGAGCA CTATGAAGCC CTGGTATCCC CCATCCTCGG ACCTCTTTTC 
ACCTACCTCC ATATGAGGCT TTCTCAGAAA TGGCAAGTTA TCAACCAAAG GAGCCTGCTG 
TGTGGAGAAG ATGAGGCTGC AGATGAAAAC CCAGAGTCTC AAGAGATGCT GGAGGAGCAA 
CTGGTGAGGA TGTTAACCCG AGAAGTCATG GACCTAATCA CGGTTTGCTG TGTTTCAAAG 
AAGGGTGCTG ACCACAGTAG TGCTCCCCCA GCAGATGGAG ACGATGAAGA AATGATGGCC 
ACAGAGGTCA CCCCCTCAGC TATGGCAGAG CTTACAGACC TGGGCAAATG TCTGATGAAG 
CATGAGGATG TTTGTACAGC GCTATTAATT ACAGCCTTCA ATTCCCTGGC CTGGAAAGAT 
ACTCTGTCCT GCCAGAGGAC AACCTCACAG CTCTGCTGGC CTCTCCTCAA ACAAGTGCTG 
TCAGGGACAC TGCTCGCAGA TGCAGTTACG TGGCTTTTCA CCAGTGTGCT GAAAGGCTTA 
CAGATGCACG GGCAGCACGA CGGGTGCATG GCTTCCCTGG TCCATCTGGC CTTCCAGATA 
TACGAGGCAC TGCGCCCCAG GTACCTGGAG ATAAGAGCTG TAATGGAGCA AATCCCTGAA 
ATACAGAAGG ACTCACTGGA CCAGTTTGAC TGCAAGCTTT TAAACCCCTC CCTGCAGAAA 
GTGGCTGACA AGCGCCGAAA GGACCAATTC AAACGCCTCA TTGCTGGTTG CATTGGGAAA 
CCCTTGGGAG AGCAGTTCCG AAAAGAAGTT CACATTAAGA ATCTTCCCTC ACTTTTCAAA 
AAAACAAAGC CAATGCTGGA GACGGAGGTG CTGGACAATG ATGGGGGTGG CCTGGCCACC 
ATCTTTGAAC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association of microRNA-related gene XPO5 rs11077 polymorphism with susceptibility to thyroid cancer.
Medicine96(14)e6351(2017 Apr)
Wen J,Gao Q,Wang N,Zhang W,Cao K,Zhang Q,Chen S,Shi L

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XPO5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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