Gene Symbol | ARID1B |
Entrez Gene ID | 57492 |
Full Name | AT-rich interaction domain 1B |
Synonyms | 6A3-5,BAF250B,BRIGHT,CSS1,DAN15,ELD/OSA1,MRD12,OSA2,P250R |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]. |
Disorder MIM: | |
Disorder Html: | Coffin-Siris syndrome 1, 135900 (3) |